Abstract：
:The opioid epidemic is a significant public health concern linked to chronic pain. Despite efforts to change opioid prescribing practices for chronic pain, opioid-involved overdoses remain at an all-time high. Research focused on identifying individual difference factors for problematic opioid misuse in the context of chronic pain have identified certain psychological variables that may confer heightened risk for opioid-related problems. Anxiety sensitivity, or fear of anxiety-related physical sensations, has been linked to opioid-related problems among adults with chronic pain. Yet, it is possible that these relations may not be distributed equally in society, and sex differences may be one avenue by which these relations differ. Therefore, the current study examined the moderating role of sex on the relation between anxiety sensitivity, current opioid misuse, and severity of opioid dependence among 428 adults (74.9% female, Mage = 38.28 years, SD = 11.06) with chronic pain. Results indicated that the relation between anxiety sensitivity and current opioid misuse (ΔR2 = 0.005, B = 0.12, SE = 0.06, p = 0.04), and opioid dependence (ΔR2 = 0.01, B = 0.04, SE = 0.02, p = 0.007) was stronger for males compared to females. These results suggest that anxiety sensitivity may be associated with opioid-related problems to a greater extent for males than females. Continued research is needed to examine how these sex differences may impact clinical treatment for opioid-related problems.
journal_name
Addict Behavjournal_title
Addictive behaviorsauthors
Rogers AH,Manning K,Garey L,Smit T,Zvolensky MJdoi
10.1016/j.addbeh.2019.106156subject
Has Abstractpub_date
2020-03-01 00:00:00pages
106156eissn
0306-4603issn
1873-6327pii
S0306-4603(19)30857-3journal_volume
102pub_type
杂志文章abstract：:It is common in addictions research for statistical analyses to include interaction effects to test moderation hypotheses. Far less commonly do researchers consider the possibility that a given predictor may exert a nonlinear effect on the outcome. This lack of attention to the possible nonlinear effects of individual...
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journal_title：Addictive behaviors
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doi：10.1016/j.addbeh.2008.07.002
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journal_title：Addictive behaviors
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