Abstract:
:Breast cancer is the most common cancer in women with rising incidence worldwide. F-FDG PET/CT imaging has already established itself as a pivotal modality for staging, restating and response assessment in patients with carcinoma breast. The complex biology of this cancer is increasingly being decoded and various molecular targets have been identified and exploited for guiding the treatment at various time points during the course of the disease. We here depict a series of various metabolic and receptor targeting PET radiotracers in breast cancer patients which may help us understand the in vivo biology of this tumor.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Vatsa R,Singh SS,Ashwathanarayana AG,Kumar R,Rana N,Shukla J,Mittal BRdoi
10.1097/RLU.0000000000002783subject
Has Abstractpub_date
2020-02-01 00:00:00pages
e72-e76issue
2eissn
0363-9762issn
1536-0229journal_volume
45pub_type
杂志文章abstract::A 75-year-old woman with a history of sarcoidosis presenting with low cardiac output and complete right bundle-branch block underwent 4'-[methyl-C]-thiothymidine (4DST) PET/CT after cardiac MRI and FDG PET/CT for the evaluation of suspected cardiac sarcoidosis (CS) before treatment. Cardiac MRI revealed late gadoliniu...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002059
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Mammographic screening has led to the identification of more women with nonpalpable breast cancer, many of them to be treated with breast-preserving surgery. To accomplish radical tumor excision, adequate localization techniques such as radioactive seed localization (RSL) are required. For RSL, a radioactive...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001081
更新日期:2016-05-01 00:00:00
abstract::Glomus tumors are tumors that arise from the glomus bodies, which can be found in sites of arteriovenous anastomosis. Glomus tumors can occur in all parts of the body but rarely occur in the trachea. The PET/CT findings of these tumors are similar to those of malignant tracheal tumors. We reported the PET/CT findings ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002897
更新日期:2020-02-01 00:00:00
abstract::Extramedullary involvement in multiple myeloma is rare, but carries poor prognosis. We describe the FDG PET-CT findings of rare adrenal involvement in a case of multiple myeloma. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002195
更新日期:2018-09-01 00:00:00
abstract::Tc-99m galactosyl-neoglycoalbumin (NGA) is a new liver imaging agent that specifically binds to a hepatocyte specific membrane receptor, the hepatic binding protein. Scintigraphy with Tc-99m NGA is a noninvasive method that provides functional images of the liver. This report deals with one case of fulminant hepatic f...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199504000-00009
更新日期:1995-04-01 00:00:00
abstract::An intraparenchymal lung tumor exhibiting the histopathologic and immunophenotypic characteristics of an intracranial meningioma is described. The tumor presented as a solitary asymptomatic pulmonary nodule with increased fluorodeoxyglucose uptake on positron emission tomography. After right upper lobectomy, benign ps...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.RLU.0000027744.41282.A9
更新日期:2002-10-01 00:00:00
abstract:: A 50-year-old-man with abdominal pain, who had undergone aortic aneurysm reconstructive surgery (aortic graft) 3 years before, was admitted to the hospital. A CT scan showed findings suggestive of perigraft infection. Scintigraphy with 99mTc-hexamethylpropylene amine oxime (HMPAO)-labeled leukocytes confirmed the dia...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3182639bd9
更新日期:2012-11-01 00:00:00
abstract::Single-photon emission computed tomography has been proven to detect more abnormalities than planar bone scintigraphy in patients with low back pain (LBP). Both 180 degrees and 360 degrees acquisitions were performed in 24 patients with LBP to determine whether the shorter 180 degrees posterior SPECT is as accurate fo...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199306000-00004
更新日期:1993-06-01 00:00:00
abstract::A 36-year-old woman presented with a calcium level of 15.7 mg/dL (normal, 8.5-11.0 mg/dL) and an extremely elevated parathyroid hormone level of 1549.6 pg/mL (normal, 10.0-65.0 pg/ mL). She subsequently underwent a parathyroid scan and ultrasound evaluation, which suggested parathyroid carcinoma. Biopsy of a lytic les...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000500
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:Tumor-induced osteomalacia (TIO) is rare paraneoplastic disorder generally caused by small benign neoplasm. Somatostatin receptor imaging has emerged as imaging of the choice in the localization of the causative tumors in new patients with clinical diagnosis of TIO. An accurate localization of the causative tum...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002458
更新日期:2019-03-01 00:00:00
abstract::Whereas benign leiomyoma of the uterus (fibroid) is very common, malignant degeneration of such fibroids to leiomyosarcoma is rare. Anatomical imaging with CT or MRI cannot differentiate between larger leiomyoma and leiomyosarcoma. Imaging with F-FDG PET/CT can be helpful in differentiating the two. High-grade F-FDG u...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001330
更新日期:2016-10-01 00:00:00
abstract::A variety of congenital and acquired etiologies can give rise to the radiographic finding of a unilateral hyperlucent lung. An unusual case of congenital lobar emphysema diagnosed in a young adult following the initial discovery of a hyperexpanded, hyperlucent lung is reported. Although subsequent bronchoscopy and rad...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:
更新日期:1990-10-01 00:00:00
abstract::The purpose of this study was to directly compare the efficacy of Tc-99m MIBI with TI-201/Tc-99m pertechnetate scintigraphy for localizing parathyroid adenomas in patients with primary hyperparathyroidism. Of 21 patients suspected of having primary hyperparathyroidism who had undergone both studies, 14 had subsequent ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199608000-00002
更新日期:1996-08-01 00:00:00
abstract::In order to evaluate the renal excretion quantitatively, the authors analyzed the Tc-99m DTPA renogram using mean transit time (MTT) with deconvolution analysis and compared it to the perfusion index. One hundred thirteen studies consisting of 25 normal, 11 obstruction, 35 transplant-norm, 12 transplant-obstruction, a...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198901000-00003
更新日期:1989-01-01 00:00:00
abstract::Single photon emission computed tomography of the brain with Tc-99m labeled hexamethylpropyleneamine oxime was used to evaluate a patient who suffered hypoxic cerebral injury. Hypoperfusion in the right parieto-occipital and left occipital regions was demonstrated on the SPECT images, while both the cranial CT and EEG...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198907000-00003
更新日期:1989-07-01 00:00:00
abstract::A 52-year-old man with metastatic poorly differentiated bronchogenic carcinoma and serum calcium levels as high as 14.6 had intense Tc-99m MDP uptake found throughout the stomach wall on SPECT imaging. FDG uptake assessed by PET imaging was not elevated in the stomach, whereas multiple hyper-metabolic tumor foci could...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199509000-00002
更新日期:1995-09-01 00:00:00
abstract::A 67-year-old woman underwent F-FDG PET/CT after developing a fever of unknown origin. PET/CT revealed intensive FDG uptake at the nasal and lung lesions. On the laboratory data, serum myeloperoxidase antineutrophil cytoplasmic antibodies (ANCA) titer was elevated, although serum directed against proteinase 3 (PR3) AN...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3182817a95
更新日期:2014-01-01 00:00:00
abstract::We present an F-18 FDG PET scan which demonstrates 3 synchronous primary malignancies. The patient is a 61-year-old man who presented with weight loss and dysphagia. He was initially diagnosed with squamous cell carcinoma of the midesophagus, and was then found to have an adenocarcinoma in the right lung. A staging PE...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3180a1ad48
更新日期:2007-08-01 00:00:00
abstract::A 52-year-old woman with right breast cancer was referred for 18F-fluoride whole-body PET/CT for the assessment of bone metastases. The peripheral i.v. access was not obtained after multiple attempts. The radiopharmaceutical was administered by oral route. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000250
更新日期:2013-12-01 00:00:00
abstract::Fifteen patients who had bilateral mediofrontal hypoactivity and 30 control subjects without this SPECT anomaly underwent Tc-99m HMPAO brain SPECT imaging. Bilateral mediofrontal hypoactivity was found in various neurologic disorders, including subcortical arteriosclerotic encephalopathy, lacunar state, chronic alcoho...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199410000-00006
更新日期:1994-10-01 00:00:00
abstract::A 15-year-old boy underwent hepatobiliary scintigraphy for suspected acute cholecystitis. The initial images revealed an activity in the neighborhood of normal gallbladder fossa, suggestive of possible activity in the gallbladder, which would be inconsistent with a diagnosis of acute cholecystitis. However, after drin...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002165
更新日期:2018-08-01 00:00:00
abstract::Ga-prostate-specific membrane antigen (Ga-PSMA) PET/CT has shown excellent results in imaging of prostate cancer. Some nonprostatic malignancies can also demonstrate Ga-PSMA uptake, including primary lung adenocarcinoma. However, no such data are present for small cell lung cancer. We present the case of a 59-year-old...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003270
更新日期:2020-12-01 00:00:00
abstract::An 85-year-old man with a 2-year history of prostate cancer, treated with radiotherapy and hormonal therapy, presented increased prostatic-specific antigen levels. F-choline PET/CT showed focal prostatic uptake consistent with known local recurrence, increased uptake of 2 hypodense thyroid nodules and of 2 left cervic...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002374
更新日期:2019-02-01 00:00:00
abstract::Tc-99m labeled RBC imaging was used to conclusively demonstrate continuing intrathoracic hemorrhage from the anastomotic site of a coronary artery bypass graft. Demonstration of continuing hemorrhage and localization of the most likely site of bleeding resulted in timely and appropriate surgical intervention, which re...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198611000-00006
更新日期:1986-11-01 00:00:00
abstract::A ureteroinguinal hernia was demonstrated on both a Tc-99m mercaptoacetyltriglycine (MAG3) renal scan and a computed tomographic scan in an 81-year-old man with suspected urinary tract infection and a prior history of transurethral resection of the prostate. Ureteral hernias are relatively rare, although the ureteroin...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.rlu.0000079396.43884.f1
更新日期:2003-08-01 00:00:00
abstract::Although the incidence of an organic cause is low and most of the detected genitourinary anomalies are not responsible for enuresis, a simple, noninvasive screening test is preferable in the analysis of children with enuresis. Extension of standard radionuclide renography as a method of screening the upper as well as ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199203000-00010
更新日期:1992-03-01 00:00:00
abstract::A prospective study of eight patients with recent transmural myocardial infarction was performed using 99mTc-Sn-pyrophosphate and 99mTc-Sn-methylene diphosphonate in each patient. All pyrophosphate scans were strongly positive whereas the diphosphonate scan was strongly positive in only one case. We conclude that 99mT...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-197903000-00001
更新日期:1979-03-01 00:00:00
abstract::Hepatobiliary imaging in a patient with an amebic abscess showed an early cold defect that later showed rim enhancement. A Tc-99m SC scan did not show prominent flow (making hepatoma unlikely) and showed the previously noted defect to appear larger and without rim enhancement. The differential damage to Kupffer cells ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198802000-00011
更新日期:1988-02-01 00:00:00
abstract::Thirty gallium scans, using currently acceptable dosage levels (5-6 mCi) and a conventional rotating gamma camera, were performed on 20 patients with lymphoma or infection. Compared to planar scans, SPECT increased sensitivity and lesion detection from 48% to 89% in lymphoma, and from 50% to 80% in infection. The pred...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198709000-00003
更新日期:1987-09-01 00:00:00
abstract::Metastatic calcifications according to histopathologic and scintigraphic findings have been well-defined. The authors report a postoperative case of hyperparathyroidism with multiple metastatic calcifications in the lung, kidney, stomach, heart, and vessels that were primarily detected by bone scintigraphy and demonst...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199202000-00010
更新日期:1992-02-01 00:00:00