Quantitative evaluation of renal excretion on the dynamic DTPA renal scan.


:In order to evaluate the renal excretion quantitatively, the authors analyzed the Tc-99m DTPA renogram using mean transit time (MTT) with deconvolution analysis and compared it to the perfusion index. One hundred thirteen studies consisting of 25 normal, 11 obstruction, 35 transplant-norm, 12 transplant-obstruction, and 30 transplant-rejection were evaluated. In the non-transplant obstruction, MTT is significantly long (3.40 +/- 0.85 minutes vs 2.02 +/- 0.42 minutes) and has high sensitivity (100%) and specificity (93%, 23/25) for the diagnosis of obstruction. In the transplant-obstruction, if the field of view includes both transplant and liver or spleen as a blood pool image, MTT has high sensitivity for the diagnosis (10/11) and for the follow up of obstruction (12/12), with the same specificity, but low sensitivity for rejection (25%). Perfusion index is of value in the diagnosis of rejection (73% specificity, 77% sensitivity) but is useless for the detection of obstruction (25% specificity, 75% sensitivity). The authors conclude that MTT is a useful marker for diagnosis and serial quantitative evaluation of renal obstruction. Also, they suggest the use of multiple techniques based on different principles for the complete evaluation of the renal scan.


Clin Nucl Med


Kubota K,Atkins HL,Anaise D,Oster ZH,Pollack W




Has Abstract


1989-01-01 00:00:00












  • Impact of Time-of-Flight Reconstruction on Cardiac PET Images of Obese Patients.

    abstract:PURPOSE:The benefit of time-of-flight (TOF) information in PET oncology studies is well established, demonstrating improved signal-to-noise ratio and enhanced lesion detection. In cardiac PET studies, tracer distribution and study interpretation differ substantially from oncology PET, and the benefit of TOF is less est...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: DiFilippo FP,Brunken RC

    更新日期:2017-02-01 00:00:00

  • Transureteroureterostomy obstruction mimicking acute tubular necrosis.

    abstract::A patient receiving nephrotoxic chemotherapy for metastatic cervical cancer was examined for acute renal failure. A Tc-99m MAG3 scan showed symmetric function, bilateral increasing parenchymal activity, and no tracer excretion in either collecting system. The differential diagnosis included cisplatin-induced nephrotox...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Esteves FP,Halkar RK,Taylor A Jr

    更新日期:2002-02-01 00:00:00

  • Liver cysts associated with polycystic kidney disease: role of Tc-99m hepatobiliary imaging.

    abstract::A 42-year-old woman with multiple hepatic cysts associated with autosomal polycystic kidney disease was evaluated for abdominal discomfort and new liver test abnormalities following blind aspirations of her liver cysts. Tc-99m mebrofenin hepatobiliary imaging revealed a markedly enlarged liver with multiple photon def...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Salam M,Keeffe EB

    更新日期:1989-11-01 00:00:00

  • Sacral Fatigue Fracture in a Military Recruit.

    abstract::A 19-year-old male military recruit presented with 3 weeks of persistent left hip and groin pain after abnormally twisting his hip during a hike. Initial radiographs were interpreted as negative. He subsequently underwent a bone scan which revealed linear left sacral uptake along or paralleling the sacroiliac joint. D...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Burgess MD,Johnston MJ,Silverman ED

    更新日期:2017-06-01 00:00:00

  • Successful Repeated Peptide Receptor Radionuclide Therapies in Renal Neuroendocrine Tumor With Osseous Metastasis.

    abstract::Renal neuroendocrine tumor (NET) is an extremely rarely occurring disease. The sporadic reports in the literature are mostly case reports, or less commonly small studies. In cases of metastatic disease from renal NET, there are no established therapies. We are reporting our experience with a patient with extensive oss...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Yordanova A,Mayer K,Essler M,Ahmadzadehfar H

    更新日期:2016-12-01 00:00:00

  • A Case of Nasal Merkel Cell Carcinoma Draining to a Buccinator Sentinel Lymph Node.

    abstract::A 73-year-old man diagnosed with Merkel cell carcinoma of the left nasal ala was referred for preoperative scintigraphic sentinel lymph node mapping. In three separate foci around the lesion, 0.2 mCi of Tc-sulfur colloid was intradermally administered. Planar images demonstrated accumulation of tracer midway between t...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Bermo MS,Leung A,Behnia F

    更新日期:2016-11-01 00:00:00

  • Radiocolloid liver imaging in tuberculous hepatitis.

    abstract::Twenty of 22 patients with tuberculous hepatitis had abnormal Tc-99m tin colloid liver scans. However, in the majority of the patients the changes were mild and nonspecific. The most frequent scintigraphic picture was a decreased uptake of the radiocolloid by the liver, with shunting to the spleen and bone marrow. The...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Essop AR,Posen JA,Savitch I,Levin J,Kew MC

    更新日期:1984-02-01 00:00:00

  • Primary Spinal Poorly Differentiated Neuroendocrine Tumor Displayed on FDG PET/CT.

    abstract::F-FDG PET/CT imaging provides valuable information in the evaluation and staging of spinal tumors. Herein, we report the case of a 57-year-old man who presented with a sudden paraplegia below the fifth thoracic vertebra due to cord compression of a spinal lesion. After spinal canal decompression and spinal lesion biop...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Shen G,Ma H,Pan L,Su M,Kuang A

    更新日期:2019-10-01 00:00:00

  • False-positive results obtained with stress myocardial SPECT in patients with right bundle branch block.

    abstract:PURPOSE:Right bundle branch block (RBBB) is a conduction defect that often is accompanied by nonspecific patient symptoms. The objective of this study was to evaluate the false-positive results obtained with TI-201 myocardial SPECT in patients with RBBB. METHODS:Thirty-one patients (24 men, 7 women; age range, 35 to 7...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Küçük NO,Arican P,Ibiş E,Aras G,Berkalp B,Oral D,Kir KM

    更新日期:2000-08-01 00:00:00

  • Increased FDG activity in a dermatofibroma in esophageal cancer patient.

    abstract::PET using the radiotracer (18)F-FDG is used for staging patients with esophageal cancer. Nonmalignant conditions, mainly inflammation and some benign tumors, however, can cloud the clinical picture by taking up FDG and producing a false-positive result. We report the case of a 46 year-old man with squamous cell carcin...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Bingham BA,Hatef DA,Chevez-Barrios P,Blackmon SH,Kim MP

    更新日期:2013-03-01 00:00:00

  • Quantitative lung scans for prediction of post-radiotherapy pulmonary function.

    abstract::Quantitative perfusion scans were used to predict the proportion of pulmonary function lost by inclusion of lung in radiotherapy fields. Nineteen patients receiving radiotherapy for carcinoma of the lung had pulmonary function evaluated by forced expiratory volume at 1 second (FEV1) prior to and following radiotherapy...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Moldofsky PJ,Rubenstein JH,Richter MP,Solin LJ,Gatenby RA,Broder GJ

    更新日期:1988-09-01 00:00:00

  • FDG PET-CT in Adrenal Multiple Myeloma.

    abstract::Extramedullary involvement in multiple myeloma is rare, but carries poor prognosis. We describe the FDG PET-CT findings of rare adrenal involvement in a case of multiple myeloma. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Choudhury S,Purandare N,Agrawal A,Shah S,Rangarajan V

    更新日期:2018-09-01 00:00:00

  • Radionuclide evaluation of doxorubicin cardiotoxicity: the need for cautious interpretation.

    abstract::Serial radionuclide angiography is a sensitive technique for the identification of asymptomatic cardiac dysfunction secondary to doxorubicin hydrochloride chemotherapy. However, the results of serial studies must be interpreted with caution in order to avoid labeling variations in the left ventricular ejection fractio...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Dey HM,Kassamali H

    更新日期:1988-08-01 00:00:00

  • The role of 99mTc-bound phosphates and grey scale echography in the differentiation of pelvic tumors.

    abstract::99mTc-pyrophosphate and 99mTc-diphosphonate have successfully been employed in the diagnosis of neoplastic pelvic disease in women. In our ongoing study, 48 women with pelvic masses, underwent dynamic pelvic scintigraphy, correlative ultrasonography and exploratory laparotomy. Dynamic scintigraphy and region of intere...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Manfredi OL,Aruny JE

    更新日期:1979-03-01 00:00:00

  • 99mTc-DISIDA uptake in liver lesion and pulmonary metastases shown on SPECT/CT in a patient with hepatocellular carcinoma.

    abstract::A 43-year-old man, previously submitted to right hepatectomy, right hepatic artery chemoembolization, and surgical resection of liver lesions, with well-differentiated and moderately differentiated hepatocellular carcinoma (HCC) confirmed by histopathology, underwent cholescintigraphy with Tc diisopropyliminodiacetic ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Ueda CE,Ichiki WA,Ruiz MF,Santos AO,Etchebehere EC

    更新日期:2014-01-01 00:00:00

  • Epstein-Barr Virus-negative posttransplant lymphoproliferative disorder with coexisting native renal cell carcinoma: PET/CT demonstration.

    abstract::Compared with the general population, solid organ transplant recipients, including renal transplant patients, who are under long-term immunosuppression, present with up to a 120-fold increased risk of developing skin cancer and non-Hodgkin lymphoma. For the renal transplant population with prior long-term dialysis, th...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Nguyen BD,Ram PC,Roarke MC

    更新日期:2006-04-01 00:00:00

  • 18F-FDG PET/CT and MRI of a Mediastinal Malignant Granular Cell Tumor With Associated Recurrent Pericarditis.

    abstract::We report a rare case of a mediastinal malignant granular cell tumor in a 41-year-old man presenting with dyspnea, retrosternal chest pain, and recurrent pericardial effusion under treatment with corticosteroids. Because of recurrent episodes, further investigations with chest MRI and F-FDG PET/CT revealed a large inf...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: D'hulst L,Deroose C,Strybol D,Coolen J,Gheysens O

    更新日期:2018-08-01 00:00:00

  • Differences in Uptake of 18F-FDG and 11C-Choline in a Case of Acute Myeloid Leukemia.

    abstract::A 26-year-old man had unilateral facial numbness. A brain MRI suggested possible brain metastases. F-FDG and C-choline PET/CT revealed multiple sites of abnormal activity in the body. However, C-choline PET/CT was more impressive than FDG PET/CT. Especially, the brain lesions revealed by MRI had only elevated C-cholin...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Qin C,Wu Z,Li J,Sun X,Lan X

    更新日期:2016-10-01 00:00:00

  • In-111 octreotide imaging in staging of small cell lung cancer.

    abstract:BACKGROUND:Small cell lung cancer (SCLC) tumors have neuroendocrine features. In vitro and in vivo studies have demonstrated that 50%-75% of SCLC tumors express receptors for somatostatin. This might enable in vivo localization of the primary tumor and its metastases by using scintigraphy with a radiolabeled somatostat...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Hochstenbag MM,Heidendal GA,Wouters EF,ten Velde GP

    更新日期:1997-12-01 00:00:00

  • Assessing Cutaneous Psoriasis Activity Using FDG-PET: Nonattenuation Corrected Versus Attenuation Corrected PET Images.

    abstract::Psoriasis is a chronic inflammatory skin condition characterized by well-circumscribed erythematous plaques with thick silvery scale. Infiltration of inflammatory cells such as lymphocytes, neutrophils, and macrophages and epidermal cell proliferation within psoriatic lesions may result in selective FDG accumulation. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Bakshi A,Gholami S,Alavi A,Gelfand JM,Takeshita J

    更新日期:2015-09-01 00:00:00

  • A study comparing SPECT and MRI in patients with anosmia after traumatic brain injury.

    abstract:PURPOSE:The initial or first clinical presentation of altered sensation of smell is directly linked to the degree of impaired sensitivity. We took the opportunity to examine normal and nonspecific MRI findings in 6 patients with known anosmia after traumatic brain injury with perfusion SPECT brain imaging. MATERIAL AN...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Mann NM,Vento JA

    更新日期:2006-08-01 00:00:00

  • Benign fibrous histiocytoma of a rib.

    abstract::Rib benign fibrous histiocytoma (BFH) is an uncommon entity. We came across a 20-year-old Chinese man who complained of right chest pain for 2 weeks. All laboratory examination results were normal. CT of the thorax revealed an expansible bone lesion in the right sixth anterior rib. Whole-body bone scan demonstrated in...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Li X,Meng Z,Li D,Tan J,Song X

    更新日期:2014-09-01 00:00:00

  • Radionuclide detection of abnormal ventricular filling patterns in rejecting human allografts.

    abstract::Parameters of systolic and diastolic function obtained from radionuclide ventriculography (RNV) were evaluated in nine cardiac allograft recipients. In 25 examinations, left end-diastolic volume (LEDV), cardiac output (CO), left ejection fraction (LEF), right ejection fraction (REF), heart rate (HR), peak filling rate...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Tatum JL,Thompson JA,Prasad U,Burke TS,Quint RI

    更新日期:1989-03-01 00:00:00

  • Conjunctival MALT lymphoma: utility of FDG PET/CT for diagnosis, staging, and evaluation of treatment response.

    abstract::A 67-year-old woman was referred for staging of a mucosa-associated lymphoid tumor lymphoma involving the left conjunctiva. CT scan had shown paravertebral and pelvic masses, and a breast nodule. FDG PET/CT demonstrated moderately increased uptake in the left ocular conjunctiva and confirmed the paravertebral and pelv...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Sallak A,Besson FL,Pomoni A,Christinat A,Adler M,Aegerter JP,Nguyen C,de Leval L,Frossard V,Prior JO

    更新日期:2014-03-01 00:00:00

  • Neonatal hypothyroid disease: absent salivary gland evident on technetium-99m pertechnetate scan.

    abstract:PURPOSE:Technetium-99m pertechnetate scintigraphy is a well-established technique for diagnosing congenital hypothyroid disease. However, the biodistribution of pertechnetate (TcO4-) in neonates and young infants is not well documented. The purpose of this study was to analyze and document the biodistribution of TcO4- ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Kiratli PO,Gordon I,Nagaraj N

    更新日期:2001-04-01 00:00:00

  • Incidental Uptake in Benign Gynecomastia on 68Ga-DOTATATE PET/CT.

    abstract::A 54-year-old man with mesenteric carcinoid tumor metastatic to the liver completed staging Ga-DOTATATE PET/CT demonstrating uptake in multiple hepatic lesions consistent with liver metastases with additional asymmetric increased uptake in the right greater than the left breast. Subsequent bilateral diagnostic mammogr...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Pandika V,Covington MF

    更新日期:2019-10-01 00:00:00

  • Diagnostic value of SPECT in a case of lower neck uptake on bone scan.

    abstract::Lower neck uptake in bone scan is hard to interpret because of superposition of several structures. Single photon emission computerized tomography can be beneficial, as illustrated in this patient with a laryngeal tumor. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Mortelmans LA,DeRoo MJ

    更新日期:1983-12-01 00:00:00

  • Gallium-positive Lyme disease myocarditis.

    abstract::In the course of a work-up for fever of unknown origin associated with intermittent arrhythmias, a gallium scan was performed which revealed diffuse myocardial uptake. The diagnosis of Lyme disease myocarditis subsequently was confirmed by serologic titers. One month following recovery from the acute illness, the abno...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Alpert LI,Welch P,Fisher N

    更新日期:1985-09-01 00:00:00

  • Quality and Safety in Health Care, Part XV: Preventing Infections Associated With Health Care.

    abstract::Infections that are associated with health care are a major problem that results in many deaths, suffering, and a great deal of extra monetary costs. Fortunately, there is much that can be done to prevent these infections. This article is a brief introduction to prevention of some of the common hospital acquired infec...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章,评审


    authors: Harolds JA

    更新日期:2016-10-01 00:00:00

  • Metastatic follicular carcinoma associated with hyperthyroidism.

    abstract:PURPOSE:A 68-year-old man with metastatic follicular thyroid carcinoma had T3 hyperthyroidism. MATERIAL AND METHODS:A bone scan showed intense uptake in the thyroid and multiple areas of increased uptake in the skeleton. Hyperthyroidism persisted after total thyroidectomy. Treatment with I-131 induced a transient stat...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Rosário F,Marques AR,Roque L,Rodrigues R,Ferreira TC,Limbert E,Sobrinho L,Leite V

    更新日期:2005-02-01 00:00:00