Quantitative evaluation of renal excretion on the dynamic DTPA renal scan.


:In order to evaluate the renal excretion quantitatively, the authors analyzed the Tc-99m DTPA renogram using mean transit time (MTT) with deconvolution analysis and compared it to the perfusion index. One hundred thirteen studies consisting of 25 normal, 11 obstruction, 35 transplant-norm, 12 transplant-obstruction, and 30 transplant-rejection were evaluated. In the non-transplant obstruction, MTT is significantly long (3.40 +/- 0.85 minutes vs 2.02 +/- 0.42 minutes) and has high sensitivity (100%) and specificity (93%, 23/25) for the diagnosis of obstruction. In the transplant-obstruction, if the field of view includes both transplant and liver or spleen as a blood pool image, MTT has high sensitivity for the diagnosis (10/11) and for the follow up of obstruction (12/12), with the same specificity, but low sensitivity for rejection (25%). Perfusion index is of value in the diagnosis of rejection (73% specificity, 77% sensitivity) but is useless for the detection of obstruction (25% specificity, 75% sensitivity). The authors conclude that MTT is a useful marker for diagnosis and serial quantitative evaluation of renal obstruction. Also, they suggest the use of multiple techniques based on different principles for the complete evaluation of the renal scan.


Clin Nucl Med


Kubota K,Atkins HL,Anaise D,Oster ZH,Pollack W




Has Abstract


1989-01-01 00:00:00












  • Painful knee joint prostheses: evaluation for loosening by combined radionuclide arthrography and transmission imaging.

    abstract:UNLABELLED:Interpretation of radionuclide arthrograms (RNA) of the knee after total knee joint replacement (TKR) may be difficult because of the lack of sufficient anatomic reference information. Additional transmission images may provide the necessary reference information required for correct interpretation of RNA of...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Hayes AA,Cardaci G,Bower GD

    更新日期:1997-10-01 00:00:00

  • Significance of solitary spine abnormalities on technetium-99m bone imaging.

    abstract::Solitary abnormalities located within the spine from 75 bone images with Tc-99m MDP were reviewed. For the sake of convenience, patients were grouped in three classes of age: 15-50, 51-65, and 66-90 years. In 67 cases, the diagnosis was apparent from clinical studies, x-ray examinations, or biopsies. In eight cases, n...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Thivolle P,Mathieu L,Mathieu P,Raynal M,Bouyoucef SE,Damideaux J,Vignon E,Berger M

    更新日期:1988-07-01 00:00:00

  • Radionuclide study of functional resolution of unilateral renal vein thrombosis.

    abstract::The diagnosis of unilateral renal vein thrombosis was established in a 50-year-old woman. A functional evaluation, by means of Tc-99m DTPA, was performed almost immediately, and at intervals up to nearly eight months later. Functional return of the involved kidney could be documented by plotting the ratio of affected ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Chapman CN,Sziklas JJ,Spencer RP,Rosenberg RJ

    更新日期:1983-11-01 00:00:00

  • Tc-99m HMPAO diffuse pulmonary uptake demonstrated in cigarette smokers.

    abstract::Tc-99m HMPAO, a lipophilic radiotracer used as a brain SPECT imaging agent in the diagnosis of strokes and dementias, is normally localized in the brain and the heart and is excreted through the kidneys (50%) and the hepatobiliary system (14% to 30%). There is no pulmonary localization except in the lungs of smokers. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Shih WJ,Gruenwald F,Biersack HJ,Berger R,Brandenburg S,Coupal J,Ryo UY

    更新日期:1991-09-01 00:00:00

  • Use of Tc-99m sestamibi infusion for detection of hibernating myocardium. A preliminary report.

    abstract::To evaluate whether a prolonged infusion of Tc-99m sestamibi allows for visualization of viable myocardium in areas of hypoperfused myocardium, 25 patients were prospectively studied. Each patient was imaged four times in two consecutive days in the following manner: day 1:1) immediately after injection of Tl-201 at r...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Miron SD,Finkelhor R,Bahler R,Sodee DB,Bellon EM

    更新日期:1995-05-01 00:00:00

  • Prognostic Value of Volumetric Parameters of Pretreatment 18F-FDG PET/CT in Esophageal Cancer: A Systematic Review and Meta-analysis.

    abstract:PURPOSE:We performed a systematic review and meta-analysis on the prognostic value of metabolic tumor volume (MTV) and total lesion glycolysis (TLG) derived from pretreatment F-FDG PET/CT in patients with esophageal cancer. METHODS:PubMed and EMBASE databases were searched until April 12, 2018, for studies that evalua...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章,meta分析


    authors: Han S,Kim YJ,Woo S,Suh CH,Lee JJ

    更新日期:2018-12-01 00:00:00

  • Outcome and toxicity associated with maximum safe dose radioiodine treatment of metastatic thyroid cancer.

    abstract:PURPOSE:This study was designed to determine the outcomes of patients referred to the authors' nuclear medicine service for dosimetric evaluation and treatment of metastatic thyroid cancer with radioiodine I-131. In addition, the incidence and severity of hematologic toxicity associated with treatment were determined. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Robeson WR,Ellwood JE,Margulies P,Margouleff D

    更新日期:2002-08-01 00:00:00

  • 18F-NaF PET/CT Findings in Fibrous Dysplasia.

    abstract::A 43-year-old woman with breast cancer underwent Tc-hydroxymethylene diphosphonate bone scintigraphy for preoperative workup. An abnormal lesion with increased uptake was found in the right humeral shaft, and F-NaF bone PET/CT was performed for clarification. There was high uptake of F-NaF without cortical bone disrup...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Lee H,Lee KS,Lee WW

    更新日期:2015-11-01 00:00:00

  • Intertumoral Heterogeneity of 18F-FDG and 68Ga-PSMA Uptake in Prostate Cancer Pulmonary Metastases.

    abstract::We present a case of a 61-year-old man with history of prostate cancer and rising PSA levels referred for restaging. Ga-PSMA-11 PET/CT identified 2 lung nodules with low and moderate PSMA uptake. Subsequent F-FDG PET/CT showed high hypermetabolism in the nodule with low PSMA uptake, and low hypermetabolism in the nodu...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Perez PM,Hope TA,Behr SC,van Zante A,Small EJ,Flavell RR

    更新日期:2019-01-01 00:00:00

  • Parathyroid Carcinoma With Marked Uptake of 99mTcO4.

    abstract:ABSTRACT:A 51-year-old man with a palpable neck mass and elevated parathyroid hormone was referred to our department for parathyroid scintigraphy. After injection of 740 MBq 99mTc-MIBI, a dual-phase scan was obtained, which revealed a persistent and intense focal hyperactivity in the left side of the neck (compatible w...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Pirayesh E,Tavakoli M

    更新日期:2021-02-01 00:00:00

  • Unusual lymph node metastases of prostate cancer detected by 18F-fluorocholine PET/CT.

    abstract::A 65-year-old patient with prostate adenocarcinoma was explored by 18F-fluorocholine (FCH) PET/CT for pretreatment staging because of a high risk of prostate cancer. Images showed multiple foci with increased uptake of 18F-FCH within some pelvic and retroperitoneal lymph nodes, osseous foci (iliac bones and sacrum), a...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Pinaquy JB,Allard JB,Cornelis F,Pasticier G,De Clermont H

    更新日期:2015-04-01 00:00:00

  • Tracheobronchomalacia incidentally detected on Tc-99m ventilation/perfusion SPECT.

    abstract::A Tc-99m Technegas MAA-SPECT was performed on an 81-year-old woman to exclude pulmonary embolism. It showed hypoperfusion and practically absent ventilation of the entire left lung, suggesting a left-sided centrally localized airway obstruction or compression with secondary hypoxic vasoconstriction. Subsequent broncho...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Deryk S,Nieboer K,Ceulemans G,Bossuyt A,Vanhove C,Everaert H

    更新日期:2009-09-01 00:00:00

  • Pelioid-type hepatocellular carcinoma masquerading as a hepatic hemangioma on technetium-99m red blood cell scintigraphy.

    abstract::Technetium-99m red blood cell (RBC) scintigraphy is a very specific method to differentiate a hemangioma from other hepatic masses. The authors report a case of hepatocellular carcinoma that showed a focal area of increased uptake on Tc-99m RBC SPECT in a 60-year-old man. Dynamic computed tomography and angiography re...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Ji EK,Ryu JS,Kang GH,Moon DH,Auh YH,Lee HK

    更新日期:2001-01-01 00:00:00

  • Combined C-11 methionine and F-18 FDG PET imaging in a case of neurosarcoidosis.

    abstract:PURPOSE:PET scanning of the brain with F-18 FDG and C-11 methionine (MET) is useful for characterizing brain lesions discovered at MRI or CT. Most positive PET scans indicate malignancy. However, this case report demonstrates positive F-18 FDG and C-11 MET PET scans in a patient with a nonmalignant condition, neurosarc...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Ng D,Jacobs M,Mantil J

    更新日期:2006-07-01 00:00:00

  • Value and Efficacy of Sentinel Lymph Node Diagnostics in Patients With Penile Carcinoma With Nonpalpable Inguinal Lymph Nodes: Five-Year Follow-up.

    abstract:PURPOSE:Sentinel lymph node biopsy (SLNB) has been described as a minimally invasive method for lymph node staging in patients with a penile carcinoma and nonpalpable inguinal nodes in national and international guidelines of involved professional societies. However, this method is rarely used. The aim of this study wa...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Lützen U,Zuhayra M,Marx M,Zhao Y,Knüpfer S,Colberg C,Jünemann KP,Naumann CM

    更新日期:2016-08-01 00:00:00

  • Pericardial mucinous adenocarcinoma on 18F-FDG PET/CT.

    abstract::A 56-year-old woman presented a history of left chest discomfort for 6 months. A prior CT revealed pericardial thickening, and malignancy cannot be excluded. For this reason, an FDG PET/CT scan was performed, which revealed abnormal activity inside the pericardium. The pathologic examination results after surgery demo...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Zhang G,Wang X,Yuan H,Zhang T

    更新日期:2014-04-01 00:00:00

  • Assessing Cutaneous Psoriasis Activity Using FDG-PET: Nonattenuation Corrected Versus Attenuation Corrected PET Images.

    abstract::Psoriasis is a chronic inflammatory skin condition characterized by well-circumscribed erythematous plaques with thick silvery scale. Infiltration of inflammatory cells such as lymphocytes, neutrophils, and macrophages and epidermal cell proliferation within psoriatic lesions may result in selective FDG accumulation. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Bakshi A,Gholami S,Alavi A,Gelfand JM,Takeshita J

    更新日期:2015-09-01 00:00:00

  • A rare case of sebaceous carcinoma with very malignant characteristics.

    abstract::A case of a sebaceous carcinoma is presented. This carcinoma of the skin appendages requires diagnosis by histopathology because the clinical appearance is often atypical. Because of the frequency of metastases to local lymph nodes and bone, a careful physical examination and appropriate radiologic/scintigraphic exami...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Verlooy H,Mortelmans L,Schiepers C,De Roo M

    更新日期:1993-05-01 00:00:00

  • Pituitary 18F-FDG Uptake Correlates With Serum TSH Levels in Subjects With Diffuse Thyroid 18F-FDG Uptake.

    abstract:PURPOSE:This study was to evaluate the relationship among FDG uptake in the pituitary gland (FDGp), FDG uptake in the thyroid gland (FDGt), and serum thyroid-stimulating hormone (TSH) levels in patients with diffuse FDGt incidentally noted on positron emission tomography/computed tomography (PET/CT). PATIENTS AND METH...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Jeong YH,Kim D,Lee JW,Rhee Y,Nam KH,Yun M,Kim CK

    更新日期:2015-08-01 00:00:00

  • Ureteral Metastasis From Prostate Cancer: A PSMA PET Pitfall.

    abstract::A 72-year-old man with a history of prostate adenocarcinoma initially managed by radical prostatectomy and salvage radiation therapy underwent resection of a left vas deferens recurrence identified on PSMA PET. Despite an initial response, PSA failed to fall below 3.5 ng/L, prompting re-evaluation with PSMA PET/CT: a ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Chaussé G,Skinnider B,Crook J,Black P,Abikhzer G,Probst S

    更新日期:2020-09-01 00:00:00

  • Synchronous pure epithelioid angiomyolipoma of the kidney and retroperitoneal schwannoma in the same patient on 18F-FDG PET/CT imaging.

    abstract::A 21-year-old woman was admitted to our hospital after incidental detection of a left renal lesion on ultrasound scan. Abdominal contrast-enhanced CT scan revealed a moderately enhanced lesion in the left kidney and a round mass with slight enhancement in the retroperitoneum. FDG PET/CT imaging was performed for whole...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Dong A,Wang Y,Zuo C

    更新日期:2013-02-01 00:00:00

  • FDG PET/CT Findings of Recurrent Respiratory Papillomatosis With Malignant Degeneration in the Lung.

    abstract::Recurrent respiratory papillomatosis is a rare benign disease caused by HPV-6 or HPV-11. The tumors may rarely undergo malignant degeneration. We performed FDG PET/CT in a patient experiencing recurrent respiratory papillomatosis who had pulmonary involvement. Although squamous cell carcinoma was detected in one of th...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Tatci E,Gokcek A,Unsal E,Cimen F,Demirag F,Yazici S,Ozmen O

    更新日期:2015-10-01 00:00:00

  • Parathyroid adenomas and hyperplasia. Dual radionuclide scintigraphy and bone densitometry studies.

    abstract::Dual radionuclide imaging of the neck (Tc-99m pertechnetate and TI-201 thallous chloride) was performed in 22 patients with chemical evidence of hyperparathyroidism (elevated blood calcium and parathormone [PTH] levels). Of these, 19 of 22 had localization of a TI-201 "excess" area on radiothallium-radiotechnetium sub...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Gupta SM,Belsky JL,Spencer RP,Frias J,Kotch P,Halpin T,Herrera NE

    更新日期:1985-04-01 00:00:00

  • SPECT in the management of patients with back pain and spondylolysis.

    abstract:PURPOSE:Single photon emission computed tomography (SPECT) bone scans of the lumbar spine were evaluated in the management of patients with low back pain and suspected spondylolysis. MATERIALS AND METHODS:Thirty-three patients (mean age, 30 years) with high clinical suspicion of pars interarticularis defects were incl...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Dutton JA,Hughes SP,Peters AM

    更新日期:2000-02-01 00:00:00

  • Imaging of irradiated liver with Tc-99m-sulfur colloid and Tc-99m-IDA.

    abstract::In three cases, irradiated regions of liver failed to concentrate Tc-99m-sulfur colloid. In two of these three, imaging with Tc-99m-acetanilide iminodiacetic acid (IDA) agents within five days showed near normal hepatic uptake of this hepatobiliary imaging agent. The hepatic parenchymal cells may be imaged with Tc-99m...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Gelfand MJ,Saha S,Aron BS

    更新日期:1981-09-01 00:00:00

  • Difficulty of diagnosing infected hypertrophic pseudarthrosis by radionuclide imaging.

    abstract::Hypertrophic pseudarthrosis was studied with Tc-99m MDP and Ga-67 citrate in 11 patients. Two of the 11 pseudarthroses were complicated by infection. A high concentration of both radiopharmaceuticals was obtained at all 11 sites and their distribution patterns were identical. It was therefore impossible to distinguish...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Hadjipavlou A,Lisbona R,Rosenthall L

    更新日期:1983-02-01 00:00:00

  • Successful Repeated Peptide Receptor Radionuclide Therapies in Renal Neuroendocrine Tumor With Osseous Metastasis.

    abstract::Renal neuroendocrine tumor (NET) is an extremely rarely occurring disease. The sporadic reports in the literature are mostly case reports, or less commonly small studies. In cases of metastatic disease from renal NET, there are no established therapies. We are reporting our experience with a patient with extensive oss...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Yordanova A,Mayer K,Essler M,Ahmadzadehfar H

    更新日期:2016-12-01 00:00:00

  • Organized urachal abscess mimicking urachal carcinoma on FDG PET/CT.

    abstract::Urachal inflammation is rarely seen in adults. Two patients with suspected abdominal tumor underwent FDG PET/CT. One patient showed an irregular hypermetabolic mass anterosuperior to the bladder. The other patient showed a thick-walled cystic mass with strong FDG uptake extending from the bladder dome to the anterior ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Dong A,Zuo C,Wang Y,Lu J,Zhu H

    更新日期:2014-01-01 00:00:00

  • Hepatitis C-related primary effusion lymphoma of the pleura and peritoneum, imaged with F-18 FDG PET/CT.

    abstract::Primary Effusion Lymphoma (PEL) is a rare form of Non-Hodgkin lymphoma that involves serous body cavities (pleural, pericardial, or peritoneal) with lymphomatous effusions in the absence of lymphadenopathy or organomegaly. Although it was seen mostly in HIV-positive patients, it has recently been reported in HIV-negat...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Makis W,Stern J

    更新日期:2010-10-01 00:00:00

  • Dual isotope F-18 FDG and Tc-99m RBC imaging for lung cancer.

    abstract:PURPOSE:To produce fluorodeoxyglucose (FDG) images with markers for normal organs and large blood vessels in patients with suspected lung cancer. METHODS:Dual isotope SPECT images were made using F-18 FDG- and Tc-99m-labeled autologous red cells. RESULTS:FDG-positive lesions are localized in relation to major structu...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章


    authors: Burt R

    更新日期:1998-12-01 00:00:00