Abstract:
PURPOSE:Tumor-induced osteomalacia (TIO) is rare paraneoplastic disorder generally caused by small benign neoplasm. Somatostatin receptor imaging has emerged as imaging of the choice in the localization of the causative tumors in new patients with clinical diagnosis of TIO. An accurate localization of the causative tumor using somatostatin receptor imaging followed by successful surgical removal offers cure of the disease. In small percentage of the patients, however, there can be recurrent disease after the surgery. In this retrospective investigation, we tried to assess whether somatostatin receptor imaging using Tc-HYNIC-TOC (Tc-hydrazinonicotinyl-Tyr3-octreotide) is also useful in patients with recurrent TIO after initial successful surgery. METHODS:The images of Tc-HYNIC-TOC images and clinical charts of total 18 patients with suspected recurrent TIO were retrospectively reviewed. The image findings were compared with the clinical chart, which include clinical follow-up and subsequent imaging and surgery. RESULTS:Among all 18 patients, Tc-HYNIC-TOC imaging results were negative in 5 of them. Among these 5 patients with negative imaging study, the causes of recurrent symptoms and hypophosphatemia in 3 patients were eventually found unrelated to TIO. Tc-HYNIC-TOC successfully identified either recurrent causative tumors in the same location (n = 10) or different causative tumor in other locations (n = 3) in 13 patients, which rendered a sensitivity of 86.7% (13 of 15). CONCLUSIONS:The efficacy of Tc-HYNIC-TOC imaging in the evaluation of patients with potential recurrent TIO is compatible to that with new patients who never received surgical resection for the culprit tumors. It can play an important role in known TIO patients who were suspected to have recurrent disease.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Shi X,Jing H,Li F,Zhao Y,Wang Z,Huo Ldoi
10.1097/RLU.0000000000002458subject
Has Abstractpub_date
2019-03-01 00:00:00pages
209-213issue
3eissn
0363-9762issn
1536-0229journal_volume
44pub_type
杂志文章abstract::Tc-99m pertechnetate radionuclide scrotal scanning was performed on nine hospitalized boys with anaphylactoid purpura and acute scrotal tenderness. Scrotal involvement in anaphylactoid purpura is generally a part of the basic pathological process (i.e., vasculitis). Sometimes testicular torsion could not be excluded b...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199304000-00006
更新日期:1993-04-01 00:00:00
abstract::While performing lymphoscintigraphy to define draining lymph node groups and sentinel nodes in patients with melanoma, the authors have discovered a new lymphatic channel in two patients with tumors in the peri-umbilical area. This channel passes over the right costal margin to an interval node before passing toward t...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199503000-00013
更新日期:1995-03-01 00:00:00
abstract:BACKGROUND:The present study aimed to better define the usefulness of F-FDG PET/CT in predicting pathological tumor response (PTR) and survival in patients with noncardia gastric cancer treated with preoperative chemotherapy. METHODS:Seventy-one patients were recruited in 6 Italian centers. The SUV of F-FDG PET/CT was...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002911
更新日期:2020-03-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31821a2a96
更新日期:2011-11-01 00:00:00
abstract:PURPOSE:To analyze the biodistribution of Ga-DOTA-TATE in the normal tissues and uptake in benign, indeterminate, and malignant lesions in a population of patients with known neuroendocrine tumors (NET) using semiquantitative standardized uptake values (SUV) measurements. METHODS:One hundred four consecutively scanned...
journal_title:Clinical nuclear medicine
pub_type: 临床试验,杂志文章
doi:10.1097/RLU.0000000000001100
更新日期:2016-06-01 00:00:00
abstract::Recurrent respiratory papillomatosis is a rare benign disease caused by HPV-6 or HPV-11. The tumors may rarely undergo malignant degeneration. We performed FDG PET/CT in a patient experiencing recurrent respiratory papillomatosis who had pulmonary involvement. Although squamous cell carcinoma was detected in one of th...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000895
更新日期:2015-10-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003237
更新日期:2020-10-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001054
更新日期:2016-03-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003180
更新日期:2020-09-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002036
更新日期:2018-05-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198309000-00006
更新日期:1983-09-01 00:00:00
abstract::In addition to imaging in the conventional positions, TI-201 myocardial imaging was also performed in a 25 degree cephalad projection. This resulted in improved imaging, especially of the inferior wall. Myocardial images are presented in five patients in whom areas of absent activity were most sharply delineated in th...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198105000-00009
更新日期:1981-05-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 临床试验,杂志文章
doi:10.1097/RLU.0b013e3181f48403
更新日期:2010-11-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章,meta分析
doi:10.1097/RLU.0000000000002291
更新日期:2018-12-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199408000-00002
更新日期:1994-08-01 00:00:00
abstract::Bone imaging using Tc-99m MDP was performed on a 68-year-old man with a newly diagnosed adenocarcinoma of the lung. The image unexpectedly showed increased activity in the heart area. Emergent echocardiography demonstrated impending pericardial tamponade. A malignant pericardial effusion was verified by pericardiocent...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198907000-00002
更新日期:1989-07-01 00:00:00
abstract:OBJECTIVE:Fibrosing alveolitis is a prominent feature of systemic sclerosis (SSc), and accounts for much of the morbidity and mortality of this disease. Sensitive techniques for the detection and monitoring of fibrosing alveolitis could target patients for early therapeutic intervention. The objective of this small pil...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199801000-00007
更新日期:1998-01-01 00:00:00
abstract::Serial radionuclide angiography is a sensitive technique for the identification of asymptomatic cardiac dysfunction secondary to doxorubicin hydrochloride chemotherapy. However, the results of serial studies must be interpreted with caution in order to avoid labeling variations in the left ventricular ejection fractio...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198808000-00002
更新日期:1988-08-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198410000-00002
更新日期:1984-10-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:
更新日期:1986-03-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001527
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200004000-00001
更新日期:2000-04-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
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更新日期:2015-09-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章,评审
doi:10.1097/00003072-200006000-00008
更新日期:2000-06-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/rlu.0b013e3182a200df
更新日期:2014-01-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-197809000-00009
更新日期:1978-09-01 00:00:00
abstract::Infantile hemangioendothelioma of the liver is benign mesenchymal tumor composed of anastomosing vascular channels lined with plump endothelial cells. It is a congenital lesion noted at birth or during the first 6 months of life. The authors report a large infantile hemangioendothelioma that was imaged with anatomical...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199604000-00006
更新日期:1996-04-01 00:00:00
abstract::A patient with bilateral adrenal hyperplasia, due to the ectopic adrenocorticotrophic hormone (ACTH) syndrome, received a 3-month course of treatment with 1,1 dichloro-2(o-chlorophenyl)-2-(p-chlorophenyl)ethane (o,p' DDD), which caused adrenal hypofunction requiring steroid therapy. Eleven months later, Cushing's synd...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198805000-00011
更新日期:1988-05-01 00:00:00
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journal_title:Clinical nuclear medicine
pub_type: 杂志文章
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更新日期:2016-12-01 00:00:00
abstract::A 74-year-old woman underwent Tl myocardial perfusion scan for cardiac symptoms; increased radiotracer accumulation in the left shoulder was found in the redistribution images only, and the shoulder was normal in the stress images. Suspecting septic arthritis subsequent investigations were performed, and peripheral T-...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000834
更新日期:2015-10-01 00:00:00