The Pharmacoepidemiology of Psychotropic Medication Use in Canadian Children from 2012 to 2016.

abstract：OBJECTIVE:Concerns about serious cardiovascular (CV) events among stimulant-treated youth have led to clinical and policy debates. Accordingly, several population-based empirical studies have assessed the risk of CV events in children and adolescents treated with stimulants. The main objective of this review was to sum...

journal_title：Journal of child and adolescent psychopharmacology

authors： Zito JM,Burcu M

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVES:The aim of this study is to identify predictors of pill placebo response and to characterize the temporal course of pill placebo response in anxious youth. METHODS:Data from placebo-treated patients (N = 76) in the Child/Adolescent Anxiety Multimodal Study (CAMS), a multisite, randomized controlled trial th...

journal_title：Journal of child and adolescent psychopharmacology

authors： Strawn JR,Dobson ET,Mills JA,Cornwall GJ,Sakolsky D,Birmaher B,Compton SN,Piacentini J,McCracken JT,Ginsburg GS,Kendall PC,Walkup JT,Albano AM,Rynn MA

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:The glutamatergic prefrontal-striatal pathway has been implicated previously in the neurobiology of attention-deficit/hyperactivity disorder (ADHD). We used short echo proton magnetic resonance spectroscopy (1H-MRS) to examine glutamate in the prefrontal cortex, left striatum, and, as a control area, the occi...

journal_title：Journal of child and adolescent psychopharmacology

authors： Carrey NJ,MacMaster FP,Gaudet L,Schmidt MH

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Weight gain due to the use of second-generation antipsychotics is a major health care issue for adult and paediatric psychiatric patients. Little is known about long-term weight gain effects of aripiprazole compared to risperidone in children and adolescents. OBJECTIVE:The primary aim of this study is to as...

journal_title：Journal of child and adolescent psychopharmacology

authors： Schoemakers RJ,van Kesteren C,van Rosmalen J,Eussen MLJM,Dieleman HG,Beex-Oosterhuis MM

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVES:To evaluate the 52-week safety/tolerability of oral olanzapine for adolescents with schizophrenia or bipolar mania and compare effectiveness of a standard versus intense behavioral weight intervention in mitigating risk of weight gain. METHODS:Patients 13-17 years old with schizophrenia (Brief Psychiatric R...

journal_title：Journal of child and adolescent psychopharmacology

authors： Detke HC,DelBello MP,Landry J,Hoffmann VP,Heinloth A,Dittmann RW

更新日期：2016-12-01 00:00:00

abstract：:This single case reports an open trial of lamotrigine in the treatment of self-injurious behavior (SIB) and epilepsy in an 18-year-old female diagnosed with generalized seizure disorder, stereotypic movement disorder, and compulsive SIB in the context of profound mental retardation. Animal models of SIB suggest that t...

journal_title：Journal of child and adolescent psychopharmacology

authors： Davanzo PA,King BH

更新日期：1996-01-01 00:00:00

abstract：:Self-report instruments commonly used to assess depression in adolescents have limited or unknown reliability and validity in this age group. We describe a new self-report scale, the Kutcher Adolescent Depression Scale (KADS), designed specifically to diagnose and assess the severity of adolescent depression. This rep...

journal_title：Journal of child and adolescent psychopharmacology

authors： LeBlanc JC,Almudevar A,Brooks SJ,Kutcher S

更新日期：2002-07-01 00:00:00

abstract：:This open-label study examined the potential efficacy of paroxetine in the treatment of children and adolescents diagnosed with dysthymia over a period of 3 months. Seven subjects were evaluated by the Hamilton Depression Rating Scale (HAM-D), by the Clinical Global Impression Severity of Illness Scale (CGI-S), and th...

journal_title：Journal of child and adolescent psychopharmacology

authors： Nobile M,Bellotti B,Marino C,Molteni M,Battaglia M

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:To assess the effect of Osmotic-Release Oral System (OROS) methylphenidate (MPH) on a variety of measures evaluating academic performance, cognition, and social behavior in children with attention-deficit/hyperactivity disorder (ADHD). METHODS:This double-blind, randomized, placebo-controlled, crossover labo...

journal_title：Journal of child and adolescent psychopharmacology

authors： Wigal SB,Wigal T,Schuck S,Brams M,Williamson D,Armstrong RB,Starr HL

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to investigate the preliminary effectiveness and safety of lamotrigine for the treatment of depressive episodes in adolescents. METHODS:This was a 12 week retrospective chart review of lamotrigine treatment among 37 adolescents (mean age 16.3±1.3 years) with depressive episodes ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Shon SH,Joo Y,Lee JS,Kim HW

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:Co-occurrence of substance use and bipolar disorders is both common and associated with poor treatment response and greater functional impairment than either disorder alone. The neurophysiological correlates of this co-morbidity however, remain unclear. In this pilot study, we compared brain morphometry betwe...

journal_title：Journal of child and adolescent psychopharmacology

authors： Jarvis K,DelBello MP,Mills N,Elman I,Strakowski SM,Adler CM

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Still little is known about neuropsychological differences between boys and girls with attention-deficit/hyperactivity disorder (ADHD) and whether there are sex-specific differences in the modulation of attentional performance by methylphenidate (MPH). METHOD:In this study, 27 males and 27 females between 8...

journal_title：Journal of child and adolescent psychopharmacology

authors： Günther T,Herpertz-Dahlmann B,Konrad K

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:To evaluate measures of sleep (exploratory endpoints) in two pivotal studies of a multilayer bead extended-release methylphenidate (MPH-MLR) treatment of attention-deficit/hyperactivity disorder in children. METHODS:Study 1 evaluated the time course of response to MPH-MLR (n = 26) patients in an analog class...

journal_title：Journal of child and adolescent psychopharmacology

authors： Owens J,Weiss M,Nordbrock E,Mattingly G,Wigal S,Greenhill LL,Chang WW,Childress A,Kupper RJ,Adjei A

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:Different methylphenidate (MPH) formulations, immediate release (IR) or extended release (ER), have been developed to treat Attention-Deficit/Hyperactivity Disorder (ADHD). A better use of these formulations, with a proper choice of their timing, dosage, and combination, can help to attain optimal therapeutic...

journal_title：Journal of child and adolescent psychopharmacology

authors： Soufsaf S,Robaey P,Bonnefois G,Nekka F,Li J

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:The purpose of this trial was to investigate the short-term safety and efficacy of quetiapine fumarate in the treatment of children and adolescents with autistic disorder (AD). METHOD:This was a 16-week, open-label trial that included 6 male subjects with a mean age of 10.9 +/- 3.3 years. All subjects met th...

journal_title：Journal of child and adolescent psychopharmacology

authors： Martin A,Koenig K,Scahill L,Bregman J

更新日期：1999-01-01 00:00:00

abstract：:The neuroanatomical model involved in the pathophysiology of obsessive-compulsive disorder (OCD) postulates a hyperactivation of orbitofrontal, limbic, and basal ganglia circuits. We report a case of OCD secondary to brain dysgerminoma affecting this circuit in an adolescent who responded to citalopram. The patient is...

journal_title：Journal of child and adolescent psychopharmacology

authors： Gamazo-Garrán P,Soutullo CA,Ortuño F

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate the link between the use of specific types of substances and suicidality in adolescent inpatients with schizophrenia and schizoaffective disorder. METHODS:We performed a 10-year naturalistic retrospective study of 178 adolescent inpatients diagnosed as suffering from ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Shoval G,Sever J,Sher L,Diller R,Apter A,Weizman A,Zalsman G

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:Although recent studies and meta-analyses confirm the efficacy of antidepressants in the acute phase of treatment for adolescent depression, there are few data available to allow assessment of the value of continued use of antidepressants in depressed adolescents after acute response. This study examines the ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Cheung A,Kusumakar V,Kutcher S,Dubo E,Garland J,Weiss M,Kiss A,Levitt A

更新日期：2008-08-01 00:00:00

abstract：OBJECTIVE:This functional magnetic resonance imaging (fMRI) study investigated the effects of pharmacotherapy on brain function underlying affect dysregulation and cognitive function in pediatric bipolar disorder (PBD). METHOD:Healthy controls (HC) (n=14; mean age =14.1 ± 2.4 years) and unmedicated PBD patients with m...

journal_title：Journal of child and adolescent psychopharmacology

authors： Pavuluri MN,Passarotti AM,Parnes SA,Fitzgerald JM,Sweeney JA

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:The present study examined the course of ADHD over 24 months in a preschool population. METHOD:n=48 preschoolers with ADHD, aged 3.0-5.11 years, subjects included in a larger sample of preschoolers with depression and other disorders (n=306) were comprehensively assessed at 3 annual time points over 24 month...

journal_title：Journal of child and adolescent psychopharmacology

authors： Tandon M,Si X,Luby J

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVES:The characterization and prediction of placebo response in clinical trials of youth with anxiety disorders have received little attention, despite the critical effects of placebo response rate on the success or failure of clinical trials. With this in mind, we sought to examine the factors that predict or in...

journal_title：Journal of child and adolescent psychopharmacology

authors： Dobson ET,Strawn JR

更新日期：2016-10-01 00:00:00

abstract：:The selective serotonin reuptake inhibitors (SSRIs) are becoming widely used in children and adolescents, with possible unexpected side effects being observed over time. SSRIs have been associated with bleeding in adults who have unremarkable routine hematologic laboratory results except abnormal bleeding time or plat...

journal_title：Journal of child and adolescent psychopharmacology

authors： Lake MB,Birmaher B,Wassick S,Mathos K,Yelovich AK

更新日期：2000-04-01 00:00:00

abstract：: Objectives: The objective of this research was to understand physician, patient, and parent perspectives on barriers to second-generation antipsychotic (SGA) medication adherence in youth with bipolar spectrum disorders, and attitudes toward treatment of SGA-related weight...

journal_title：Journal of child and adolescent psychopharmacology

authors： Klein CC,Topalian AG,Starr B,Welge J,Blom T,Starr C,Deetz I,Turner H,Sage J,Utecht J,Fornari V,Patino Duran L,Higdon C,Sutton JJ,Sorter MT,Correll CU,DelBello MP

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to demonstrate the superior efficacy of atomoxetine with respect to placebo and to compare parent and child perceptions of health-related quality of life (HRQoL). METHOD:This randomized, placebo-controlled, 12-week parallel clinical trial included 151 untreated children/adolescents ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Escobar R,Montoya A,Polavieja P,Cardo E,Artigas J,Hervas A,Fuentes J

更新日期：2009-06-01 00:00:00

abstract：:ABSTRACT The pertinent literature was reviewed on cardiovascular changes induced by psychostimulant medication treatment of hyperactive children. An assessment of 15 controlled studies using test doses of methylphenidate revealed a significant elevation of the resting heart rate in previously unmedicated children (mea...

journal_title：Journal of child and adolescent psychopharmacology

authors： Safer DJ

更新日期：1992-01-01 00:00:00

abstract：:Low concentrations of the neurotransmitter serotonin and its 5-hydroxyindoleacetic acid metabolite in the central nervous system have been associated with increased aggressive behavior in animals and humans. Controlled clinical trials of serotonin agonists in depressed adults have suggested that aggressive behavior is...

journal_title：Journal of child and adolescent psychopharmacology

authors： Constantino JN,Liberman M,Kincaid M

更新日期：1997-04-01 00:00:00

abstract：: Objective: Pediatric autoimmune neuropsychiatric disorder associated with Streptococcus pyogenes infection (PANDAS) and pediatric acute-onset neuropsychiatric syndrome (PANS) are emerging immune-mediated encephalopathies characterized by sudden onset of seemingly inexplica...

journal_title：Journal of child and adolescent psychopharmacology

authors： Lepri G,Rigante D,Bellando Randone S,Meini A,Ferrari A,Tarantino G,Cunningham MW,Falcini F

更新日期：2019-10-01 00:00:00

abstract：:ABSTRACT Clinical trials with a treatment duration of at least 3 months were reviewed to determine the effect of psychostimulants on the core symptoms of attention-deficit hyperactivity disorder (ADHD) and on its commonly associated features. Eighteen studies were identified: 17 were studies of methylphenidate, 1 was ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Schachar R,Tannock R

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVE:To compare fast versus slow switching from stimulants to atomoxetine (ATX) in children and adolescents with attention-deficit/hyperactivity disorder (ADHD). METHODS:This was a randomized, controlled, open-label study in 6-16-year-old ADHD patients, previously treated with stimulants and cross-titrated (fast ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Cardo E,Porsdal V,Quail D,Fuentes J,Steer C,Montoya A,Anand E,Escobar R

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to compare the efficacy and tolerability of quetiapine and divalproex for the treatment of impulsivity and reactive aggression in adolescents with co-occurring bipolar disorder and disruptive behavior disorders. METHOD:Patients were included in this post hoc analysis if they scored ...

journal_title：Journal of child and adolescent psychopharmacology

authors： Barzman DH,DelBello MP,Adler CM,Stanford KE,Strakowski SM

更新日期：2006-12-01 00:00:00