当前位置： SCI文献检索 > JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY期刊下所有文献 > Neuroanatomic comparison of bipolar adolescents with and without cannabis use disorders.

Neuroanatomic comparison of bipolar adolescents with and without cannabis use disorders.

Abstract：

OBJECTIVE:Co-occurrence of substance use and bipolar disorders is both common and associated with poor treatment response and greater functional impairment than either disorder alone. The neurophysiological correlates of this co-morbidity however, remain unclear. In this pilot study, we compared brain morphometry between bipolar adolescents with co-occurring cannabis use disorders (CUD) and bipolar adolescents without any substance use disorder. METHODS:Whole-brain structural magnetic resonance imaging (MRI) scans were obtained from 14 bipolar adolescents. Seven study participants were diagnosed with CUD before and/or shortly after their MR scan was obtained, and 7 subjects were free of any substance use disorder at the time of their MR scan as well as during longitudinal follow up. Morphologic differences were calculated using voxel-based morphometry implemented using statistical parametric mapping software (SPM2). RESULTS:Bipolar adolescents with co-occurring CUD demonstrated decreased gray matter volume (GMV) in the left fusiform gyrus and increased GMV in the right caudate and precentral gyrus, as well as increased gray matter density in the right middle occipital and fusiform gyri and cerebellar vermis. CONCLUSIONS:Bipolar adolescents with CUD demonstrate evidence of greater structural abnormalities than adolescents with bipolar disorder alone in frontal and temporal cortical regions, as well as in subcortical areas linked with emotion and motivational regulation. Although the limited prescan exposure to marijuana in these adolescents tentatively suggests that these findings may reflect underlying differences, the direct effect of cannabis exposure may also be involved.

journal_name

J Child Adolesc Psychopharmacol

journal_title

Journal of child and adolescent psychopharmacology

authors

Jarvis K,DelBello MP,Mills N,Elman I,Strakowski SM,Adler CM

doi

10.1089/cap.2008.033

subject

Has Abstract

pub_date

2008-12-01 00:00:00

pages

557-63

issue

6

eissn

1044-5463

issn

1557-8992

journal_volume

18

pub_type

杂志文章

相关文献

JOURNAL OF CHILD AND ADOLESCENT PSYCHOPHARMACOLOGY文献大全
  • Ziprasidone in adolescents with autism: an open-label pilot study.

    abstract：INTRODUCTION:The antipsychotic drugs are the best-studied agents shown to reduce symptoms in autism, including hyperactivity, aggression, self-abusive behavior, temper tantrums, lability, irritability, social withdrawal, and stereotypical behaviors. However, significant weight gain has been associated with use of many ...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章

    doi：10.1089/cap.2006.0126

    authors： Malone RP,Delaney MA,Hyman SB,Cater JR

    更新日期：2007-12-01 00:00:00

  • A pilot study of methylphenidate preference assessment in children diagnosed with attention-deficit/hyperactivity disorder.

    abstract：OBJECTIVE:The use of methylphenidate (MPH) in the treatment of attention-deficit/hyperactivity disorder (ADHD) is widely accepted; however, there is increased concern regarding its abuse potential. Few studies have examined the reinforcing effects of drugs in individuals receiving them for clinical purposes. This study...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 临床试验,杂志文章

    doi：10.1089/cap.2005.15.729

    authors： MacDonald Fredericks E,Kollins SH

    更新日期：2005-10-01 00:00:00

  • Drug-metabolizing enzyme genotypes and aggressive behavior treatment response in hospitalized pediatric psychiatric patients.

    abstract：OBJECTIVE:The aim of this study was to examine the association between the CYP2D6 and CYP2C19 genotype-predicted combined phenotypes and short-term measures of psychotropic efficacy and toxicity. METHODS:A rater-blinded, retrospective genotype association design examined a cohort of hospitalized pediatric psychiatric ...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章

    doi：10.1089/cap.2008.0103

    authors： Prows CA,Nick TG,Saldaña SN,Pathak S,Liu C,Zhang K,Daniels ZS,Vinks AA,Glauser TA

    更新日期：2009-08-01 00:00:00

  • Clinical-Serological Characterization and Treatment Outcome of a Large Cohort of Italian Children with Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infection and Pediatric Acute Neuropsychiatric Syndrome.

    abstract：: Objective: Pediatric autoimmune neuropsychiatric disorder associated with Streptococcus pyogenes infection (PANDAS) and pediatric acute-onset neuropsychiatric syndrome (PANS) are emerging immune-mediated encephalopathies characterized by sudden onset of seemingly inexplica...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章

    doi：10.1089/cap.2018.0151

    authors： Lepri G,Rigante D,Bellando Randone S,Meini A,Ferrari A,Tarantino G,Cunningham MW,Falcini F

    更新日期：2019-10-01 00:00:00

  • Switching, cycling, and antidepressant-induced effects on cycle frequency and course of illness in adult bipolar disorder: a brief review and commentary.

    abstract：:The potential for the induction of mania, increased cycle frequency, and other behavioral adverse events associated with antidepressant exposure in patients with bipolar disorder is becoming an increasingly important area of research study, as this diagnosis receives wider recognition in youth. While the majority of s...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章,评审

    doi：10.1089/104454603322163880

    authors： Papolos DF

    更新日期：2003-07-01 00:00:00

  • Effects of serotonin reuptake inhibitors on aggressive behavior in psychiatrically hospitalized adolescents: results of an open trial.

    abstract：:Low concentrations of the neurotransmitter serotonin and its 5-hydroxyindoleacetic acid metabolite in the central nervous system have been associated with increased aggressive behavior in animals and humans. Controlled clinical trials of serotonin agonists in depressed adults have suggested that aggressive behavior is...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 临床试验,杂志文章

    doi：10.1089/cap.1997.7.31

    authors： Constantino JN,Liberman M,Kincaid M

    更新日期：1997-04-01 00:00:00

  • No Differences in Weight Gain Between Risperidone and Aripiprazole in Children and Adolescents After 12 Months.

    abstract：BACKGROUND:Weight gain due to the use of second-generation antipsychotics is a major health care issue for adult and paediatric psychiatric patients. Little is known about long-term weight gain effects of aripiprazole compared to risperidone in children and adolescents. OBJECTIVE:The primary aim of this study is to as...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章

    doi：10.1089/cap.2018.0111

    authors： Schoemakers RJ,van Kesteren C,van Rosmalen J,Eussen MLJM,Dieleman HG,Beex-Oosterhuis MM

    更新日期：2019-04-01 00:00:00

  • Comorbid anxiety and social avoidance in treatment of severe childhood aggression: response to adding risperidone to stimulant and parent training; mediation of disruptive symptom response.

    abstract：OBJECTIVE:In the four-site Treatment of Severe Childhood Aggression (TOSCA) study, addition of risperidone to stimulant and parent training moderately improved parent-rated disruptive behavior disorder (DBD) symptoms. This secondary study explores outcomes other than DBD and attention-deficit/hyperactivity disorder (AD...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章,随机对照试验

    doi：10.1089/cap.2014.0104

    authors： Arnold LE,Gadow KD,Farmer CA,Findling RL,Bukstein O,Molina BS,Brown NV,Li X,Rundberg-Rivera EV,Bangalore S,Buchan-Page K,Hurt EA,Rice R,McNamara NK,Aman MG

    更新日期：2015-04-01 00:00:00

  • Decreasing Trend in the Use and Long-Term Use of Benzodiazepines Among Young Adults.

    abstract：OBJECTIVE:Patterns of benzodiazepine (BZD) use and long-term use among young adults are not well known. Our aim was to study trends in BZD use and long-term use among 18-25-year-old young adults by gender and active substance in a nationwide retrospective longitudinal register-based setting. METHODS:All Finns aged 18-...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章

    doi：10.1089/cap.2017.0140

    authors： Tähkäpää SM,Saastamoinen L,Airaksinen M,Tuulio-Henriksson A,Aalto-Setälä T,Kurko T

    更新日期：2018-05-01 00:00:00

  • A 52-Week Study of Olanzapine with a Randomized Behavioral Weight Counseling Intervention in Adolescents with Schizophrenia or Bipolar I Disorder.

    abstract：OBJECTIVES:To evaluate the 52-week safety/tolerability of oral olanzapine for adolescents with schizophrenia or bipolar mania and compare effectiveness of a standard versus intense behavioral weight intervention in mitigating risk of weight gain. METHODS:Patients 13-17 years old with schizophrenia (Brief Psychiatric R...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1089/cap.2016.0010

    authors： Detke HC,DelBello MP,Landry J,Hoffmann VP,Heinloth A,Dittmann RW

    更新日期：2016-12-01 00:00:00

  • Efficacy, long-term safety, and tolerability of ziprasidone in children and adolescents with bipolar disorder.

    abstract：OBJECTIVE:The purpose of this study was to evaluate the short- and long-term efficacy and safety of ziprasidone in children and adolescents with bipolar I disorder. METHODS:Subjects 10-17 years of age with a manic or mixed episode associated with bipolar I disorder participated in a 4 week, randomized, double-blind, p...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1089/cap.2012.0029

    authors： Findling RL,Cavuş I,Pappadopulos E,Vanderburg DG,Schwartz JH,Gundapaneni BK,DelBello MP

    更新日期：2013-10-01 00:00:00

  • Does pharmacotherapy for attention-deficit/hyperactivity disorder predict risk of later major depression?

    abstract：OBJECTIVE:This study's goal was to determine among youths with attention-deficit/hyperactivity disorder (ADHD) how the history of ADHD pharmacotherapy influenced the risk of developing major depressive disorder (MDD), compared to other commonly reported predictors. METHOD:Diagnostic and treatment history data were ana...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章

    doi：10.1089/cap.2007.0100

    authors： Daviss WB,Birmaher B,Diler RS,Mintz J

    更新日期：2008-06-01 00:00:00

  • A systematic review of combination therapy with stimulants and atomoxetine for attention-deficit/hyperactivity disorder, including patient characteristics, treatment strategies, effectiveness, and tolerability.

    abstract：OBJECTIVE:The purpose of this article was to systematically review the literature on stimulant and atomoxetine combination therapy, in particular: 1) Characteristics of patients with attention-deficit/hyperactivity disorder (ADHD) given combination therapy, 2) treatment strategies used, 3) efficacy and effectiveness, a...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章,评审

    doi：10.1089/cap.2012.0093

    authors： Treuer T,Gau SS,Méndez L,Montgomery W,Monk JA,Altin M,Wu S,Lin CC,Dueñas HJ

    更新日期：2013-04-01 00:00:00

  • Pharmacokinetics of methylphenidate in preschoolers with attention-deficit/hyperactivity disorder.

    abstract：OBJECTIVE:The aim of this study was to compare the pharmacokinetics of immediate-release methylphenidate (MPH) in preschool and school-aged children with attention-deficit/hyperactivity disorder (ADHD). METHODS:Preschool children 4-5 years (n = 14) and school-aged children 6-8 years (n = 9) with diagnoses of ADHD were...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 临床试验,杂志文章

    doi：10.1089/cap.2007.0043

    authors： Wigal SB,Gupta S,Greenhill L,Posner K,Lerner M,Steinhoff K,Wigal T,Kapelinski A,Martinez J,Modi NB,Stehli A,Swanson J

    更新日期：2007-04-01 00:00:00

  • Effectiveness of methylphenidate in the 10-month continuation phase of the Preschoolers with Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS).

    abstract：OBJECTIVE:The aim of this study was to examine immediate-release methylphenidate effectiveness during the 10-month open-label continuation phase of the Preschoolers with Attention-Deficit/Hyperactivity Disorder (ADHD) Treatment Study (PATS). METHODS:One hundred and forty preschoolers with ADHD, who had improved with a...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章

    doi：10.1089/cap.2007.0058

    authors： Vitiello B,Abikoff HB,Chuang SZ,Kollins SH,McCracken JT,Riddle MA,Swanson JM,Wigal T,McGough JJ,Ghuman JK,Wigal SB,Skrobala AM,Davies M,Posner K,Cunningham C,Greenhill LL

    更新日期：2007-10-01 00:00:00

  • Developing Rapport and Therapeutic Alliance During Telemental Health Sessions with Children and Adolescents.

    abstract：OBJECTIVE:The purpose of this study was to describe the special considerations for building rapport and establishing a therapeutic alliance when conducting mental health evaluations for children and adolescents via videoconferencing. METHODS:The authors review the literature and describe their experience in conducting...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章

    doi：10.1089/cap.2015.0022

    authors： Goldstein F,Glueck D

    更新日期：2016-04-01 00:00:00

  • Methodological issues in designing a multisite trial of risperidone in children and adolescents with autism.

    abstract：OBJECTIVE:To describe the methodological challenges and decisions made in developing a multisite, controlled study of risperidone in children and adolescents with autism. METHODS:Review the design considerations for clinical trials in children with autistic disorder accompanied by severe tantrums, aggressive and/or se...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1089/104454601317261555

    authors： Scahill L,McCracken J,McDougle CJ,Aman M,Arnold LE,Tierney E,Cronin P,Davies M,Ghuman J,Gonzalez N,Koenig K,Lindsay R,Martin A,McGough J,Posey DJ,Swiezy N,Volkmar F,Ritz L,Vitiello B

    更新日期：2001-01-01 00:00:00

  • Risperidone-related improvement of irritability in children with autism is not associated with changes in serum of epidermal growth factor and interleukin-13.

    abstract：:Risperidone has been shown to improve serious behavioral problems in children with autism. Here we asked whether risperidone-associated improvement was related to changes in concentrations of inflammatory molecules in the serum of these subjects. Seven molecules were identified as worthy of further assessment by perfo...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章

    doi：10.1089/cap.2010.0134

    authors： Tobiasova Z,van der Lingen KH,Scahill L,Leckman JF,Zhang Y,Chae W,McCracken JT,McDougle CJ,Vitiello B,Tierney E,Aman MG,Arnold LE,Katsovich L,Hoekstra PJ,Volkmar F,Bothwell AL,Kawikova I

    更新日期：2011-12-01 00:00:00

  • Aripiprazole in children and adolescents with Tourette's disorder: an open-label safety and tolerability study.

    abstract：OBJECTIVE:The aim of this study was to conduct a prospective safety and tolerability study of aripiprazole for the treatment of tics in children and adolescents with Tourette's disorder (TD). METHOD:Eleven subjects (10 males) with TD (age 9-19 years, mean 13.36, standard deviation [SD] 3.33) who did not respond or wer...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 临床试验,杂志文章

    doi：10.1089/cap.2009.0035

    authors： Lyon GJ,Samar S,Jummani R,Hirsch S,Spirgel A,Goldman R,Coffey BJ

    更新日期：2009-12-01 00:00:00

  • Antidepressant use in children and adolescents in Germany.

    abstract：OBJECTIVE:The expanded use of antidepressants in youth has been the subject of numerous studies and some concerns in recent years. This study describes prescription patterns of antidepressants (ATD) for youths in Germany for the years 2000-2003 and includes prescription use of St. John's Wort. METHODS:Prescription dat...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章

    doi：10.1089/cap.2006.16.197

    authors： Fegert JM,Kölch M,Zito JM,Glaeske G,Janhsen K

    更新日期：2006-02-01 00:00:00

  • Screening for adolescent depression: comparison of the Kutcher Adolescent Depression Scale with the Beck depression inventory.

    abstract：:Self-report instruments commonly used to assess depression in adolescents have limited or unknown reliability and validity in this age group. We describe a new self-report scale, the Kutcher Adolescent Depression Scale (KADS), designed specifically to diagnose and assess the severity of adolescent depression. This rep...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章

    doi：10.1089/104454602760219153

    authors： LeBlanc JC,Almudevar A,Brooks SJ,Kutcher S

    更新日期：2002-07-01 00:00:00

  • Persistence of stimulants in children and adolescents with attention-deficit/hyperactivity disorder.

    abstract：OBJECTIVE:To examine the persistence of three newly initiated stimulant preparations among Medicaid children and adolescents with attention-deficit/hyperactivity disorder (ADHD) diagnosis. METHODS:A retrospective longitudinal claims analysis was conducted by using Medicaid analytical eXtract data of four states. The s...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章

    doi：10.1089/cap.2011.0028

    authors： Palli SR,Kamble PS,Chen H,Aparasu RR

    更新日期：2012-04-01 00:00:00

  • Quetiapine monotherapy in adolescents with bipolar disorder comorbid with conduct disorder.

    abstract：:Bipolar Disorders (BD) are often comorbid with disruptive behaviour disorders (DBDs) (oppositional-defiant disorder or conduct disorder), with negative implications on treatment strategy and outcome. The aim of this study was to assess the efficacy of quetiapine monotherapy in adolescents with BD comorbid with conduct...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章

    doi：10.1089/cap.2013.0063

    authors： Masi G,Pisano S,Pfanner C,Milone A,Manfredi A

    更新日期：2013-10-01 00:00:00

  • Efficacy and safety of quetiapine in adolescents with schizophrenia investigated in a 6-week, double-blind, placebo-controlled trial.

    abstract：OBJECTIVE:The purpose of this study was to evaluate the efficacy and safety of acute quetiapine monotherapy in adolescents with schizophrenia. METHODS:Patients ages 13-17 years with an American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders, 4th ed., Text Revision (DSM-IV-TR) diagnosis ...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章,随机对照试验

    doi：10.1089/cap.2011.0092

    authors： Findling RL,McKenna K,Earley WR,Stankowski J,Pathak S

    更新日期：2012-10-01 00:00:00

  • Successful Use of Sertindole for Severe Behavioral Dyscontrol in a Pediatric Case of Syndromic Autism Spectrum Disorder.

    abstract：:Autism spectrum disorder (ASD) is commonly associated with a host of challenging behaviors. Pharmacotherapy is indicated if psychosocial and educational interventions fail. Atypical antipsychotics have the strongest evidence base so far, with both risperidone and aripiprazole being FDA approved. Unfortunately, their u...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章

    doi：10.1089/cap.2016.0182

    authors： Naguy A

    更新日期：2017-06-01 00:00:00

  • The efficacy and tolerability of quetiapine versus divalproex for the treatment of impulsivity and reactive aggression in adolescents with co-occurring bipolar disorder and disruptive behavior disorder(s).

    abstract：OBJECTIVE:The aim of this study was to compare the efficacy and tolerability of quetiapine and divalproex for the treatment of impulsivity and reactive aggression in adolescents with co-occurring bipolar disorder and disruptive behavior disorders. METHOD:Patients were included in this post hoc analysis if they scored ...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章,随机对照试验

    doi：10.1089/cap.2006.16.665

    authors： Barzman DH,DelBello MP,Adler CM,Stanford KE,Strakowski SM

    更新日期：2006-12-01 00:00:00

  • Adjunctive Amantadine Treatment for Aggressive Behavior in Children: A Series of Eight Cases.

    abstract：PURPOSE:Amantadine has a growing body of evidence for the treatment of aggressive behavior in patients with traumatic brain injury, autism spectrum disorder, and developmental disability. We describe our experience with adjunctive amantadine treatment for aggressive behavior in eight hospitalized children. METHODS:We ...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章

    doi：10.1089/cap.2016.0042

    authors： McGrane IR,Loveland JG,Zaluski HJ

    更新日期：2016-12-01 00:00:00

  • The effect of fluvoxamine and behavior therapy on children and adolescents with obsessive-compulsive disorder.

    abstract：OBJECTIVE:The efficacy of medications, consisting of serotonin partial and specific reuptake blockers, and behavior therapy, consisting of exposure and response prevention in addition to social skills training, cognitive therapy, and habit reversal, in the treatment of obsessive-compulsive disorder are well documented....

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1089/cap.2000.10.295

    authors： Neziroglu F,Yaryura-Tobias JA,Walz J,McKay D

    更新日期：2000-01-01 00:00:00

  • Treatment receipt and outcomes from a clinic employing the attention-deficit/hyperactivity disorder treatment guideline of the children's medication algorithm project.

    abstract：OBJECTIVE:Little is known about the pattern of service receipt and outcomes from clinics implementing best practice guidelines in child mental health. This study aimed to determine these variables for a clinic that implemented an attention-deficit/hyperactivity disorder (ADHD) treatment guideline proposed by the Childr...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 杂志文章

    doi：10.1089/cap.2014.0014

    authors： Wagner DJ,Vallerand IA,McLennan JD

    更新日期：2014-11-01 00:00:00

  • Risperidone treatment of children with autistic disorder: effectiveness, tolerability, and pharmacokinetic implications.

    abstract：BACKGROUND:Recent evidence indicates that atypical antipsychotics represent a promising option for the treatment of autistic disorder. In particular, risperidone appears to be effective in treating aggressiveness, hyperactivity, irritability, stereotypies, social withdrawal, and lack of interests. OBJECTIVE:The aim of...

    journal_title：Journal of child and adolescent psychopharmacology

    pub_type： 临床试验,杂志文章

    doi：10.1089/104454604773840472

    authors： Gagliano A,Germanò E,Pustorino G,Impallomeni C,D'Arrigo C,Calamoneri F,Spina E

    更新日期：2004-04-01 00:00:00