Abstract:
Background:To evaluate the influence of tumor depth on preoperative computed tomography (CT) image, and resection margin length on local recurrence after pulmonary metastasectomy of colorectal cancer. Methods:Patients undergoing thoracoscopic pulmonary wedge resection for single pulmonary metastasis of colorectal cancer origin from 2007 to 2017 were analyzed. Factors such as resection margin, tumor size and depth were analyzed. The local recurrences of two subgroups based on the pulmonary resection margin (Group 1: resection margin 1-10 mm or shorter than the tumor size, Group 2: resection margin >10 mm or at least greater than the tumor size) were analyzed. Results:Sixty-five patients were included in this study. The local recurrence rate was 12/65 (18.5%). Median follow up period was 33 months. Median tumor size and depth on preoperative CT were 1.1 and 1.6 cm. Median length of resection margin was 0.5 cm (group 1: 0.4 cm, group 2: 1.0 cm, P<0.001). No difference was noted in 3-year local recurrence-free survival (80.8% vs. 76.7%, P=0.756) between the two subgroups. No significant correlation was noted between the length of resection margin and the tumor size and depth. However, tumor depth was an independent factor related to higher local recurrence on multivariate analysis. Conclusions:Extent of resection margin in pulmonary metastasectomy does not seem to affect significantly on the local recurrence if complete resection is accomplished. However, preoperative tumor depth on CT image and postoperative distant metastasis seem to affect on local recurrence after pulmonary metastasectomy.
journal_name
J Thorac Disjournal_title
Journal of thoracic diseaseauthors
Chung JH,Lee SH,Yi E,Lim JY,Jung JS,Son HS,Sun Kdoi
10.21037/jtd.2019.05.12subject
Has Abstractpub_date
2019-05-01 00:00:00pages
1879-1887issue
5eissn
2072-1439issn
2077-6624pii
jtd-11-05-1879journal_volume
11pub_type
杂志文章abstract::Interstitial lung diseases (ILDs) form one of the most fascinating fields in pulmonary medicine. They also pose one of the greatest challenges for accurate diagnosis and proper treatment. Even within the recommended and warranted multidisciplinary approach, differentiating between one disease and another may lead to f...
journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
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journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
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journal_title:Journal of thoracic disease
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journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
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journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
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更新日期:2014-04-01 00:00:00
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pub_type: 杂志文章
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
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journal_title:Journal of thoracic disease
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2018.08.68
更新日期:2018-09-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
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journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
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journal_title:Journal of thoracic disease
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
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journal_title:Journal of thoracic disease
pub_type:
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journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
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journal_title:Journal of thoracic disease
pub_type:
doi:10.3978/j.issn.2072-1439.2014.02.04
更新日期:2014-02-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.3978/j.issn.2072-1439.2014.09.17
更新日期:2014-10-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
doi:10.21037/jtd.2020.03.85
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
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更新日期:2014-12-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type: 杂志文章,评审
doi:10.3978/j.issn.2072-1439.2014.08.43
更新日期:2014-09-01 00:00:00
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journal_title:Journal of thoracic disease
pub_type: 杂志文章
doi:10.21037/jtd.2019.01.07
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