Hyperprogressive disease in patients with non-small cell lung cancer on immunotherapy.

abstract：BACKGROUND:Glucose-insulin-potassium (GIK) demonstrates a cardioprotective effect by providing metabolic support and anti-inflammatory action, and may be useful in septic myocardial depression. The aim of this study was to examine the relationship between GIK and hemodynamic outcomes in septic shock patients with myoca...

journal_title：Journal of thoracic disease

authors： Kim WY,Baek MS,Kim YS,Seo J,Huh JW,Lim CM,Koh Y,Hong SB

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:Epidermal growth factor receptor (EGFR) mutation mostly occurred in lung adenocarcinoma, rarely in squamous cell carcinoma (SQCC). EGFR mutation rate in SQCC varied in previous reports, and the efficacy of EGFR tyrosine kinase inhibitors (TKIs) in SQCC harboring EGFR mutation has not yet been fully evaluated....

journal_title：Journal of thoracic disease

authors： Fang W,Zhang J,Liang W,Huang Y,Yan Y,Wu X,Hu Z,Ma Y,Zhao H,Zhao Y,Yang Y,Xue C,Zhang J,Zhang L

更新日期：2013-10-01 00:00:00

abstract：:Liquid biopsy provides the opportunity of detecting and analyzing cancer in various body fluids. In peripheral blood, apart from circulating cell free DNA, circulating cancer cells and other tumor-associated compounds such as extracellular vesicles are also emerging candidates for detection. Compared to conventional t...

journal_title：Journal of thoracic disease

authors： Cheung AH,Chow C,To KF

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Subxiphoid thoracoscopic surgery has been used in various thoracic surgical procedures. The aim of this study is to compare the physiological and inflammatory responses between subxiphoid thoracoscopic surgery and standard transthoracic thoracoscopic surgery for anatomic pulmonary lobectomy in a canine model...

journal_title：Journal of thoracic disease

authors： Wen CT,Chu Y,Wu YC,Hsieh MJ,Liu CY,Liu CC,Ko PJ,Liu YH,Liu HP

更新日期：2015-11-01 00:00:00

abstract：Background:Outcome of patients with advanced non-small cell lung cancer (NSCLC) treated with platinum-based doublet chemotherapy is usually poor, with overall survival ranges from 8-13 months. However, the overall survival is improved to 21-28 months in the era of epidermal growth factor receptor (EGFR) tyrosine kinase...

journal_title：Journal of thoracic disease

authors： Huang CY,Chen BH,Chou WC,Yang CT,Chang JW

更新日期：2018-04-01 00:00:00

abstract：Background:Although robot-assisted minimally-invasive esophagectomy (RAMIE) surgeries are expanding clinically, few studies have reported patients with locally-advanced esophageal cancer who underwent neoadjuvant chemoradiation therapy (nCRT). Methods:From 2013 to 2017, 219 patients with esophageal squamous cell carci...

journal_title：Journal of thoracic disease

authors： Yun JK,Lee IS,Gong CS,Kim BS,Kim HR,Kim DK,Park SI,Kim YH

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:Recurrence of pectus excavatum (PE) is not an uncommon problem after open repair using the Ravitch technique. The optimal approach for redo surgery is still under debate, especially in adults with less chest wall pliability. Aim of this study was to investigate the usefulness and efficacy of the minimally in...

journal_title：Journal of thoracic disease

authors： Kocher GJ,Gstrein N,Jaroszewski DE,Ewais MM,Schmid RA

更新日期：2016-08-01 00:00:00

abstract：Background:Allergic asthma is a complex genetic disorder that involves interactions between genetic and environmental factors. Usage of PTEN may be a good therapeutic strategy for the management of allergic inflammation. Thus, the present study aims to explore the effects of phosphatase and tensin homolog (PTEN) gene s...

journal_title：Journal of thoracic disease

authors： Wen X,Yan J,Han XR,Zheng GH,Tang R,Liu LF,Wu DM,Lu J,Zheng YL

更新日期：2018-01-01 00:00:00

abstract：:We have entered an open access publishing era. The impact and significance of open access is still under debate after two decades of evolution. Open access journals benefit researchers and the general public by promoting visibility, sharing and communicating. Non-mainstream journals should turn the challenge of open a...

journal_title：Journal of thoracic disease

authors： Dai N,Xu D,Zhong X,Li L,Ling Q,Bu Z

更新日期：2014-05-01 00:00:00

abstract：Background:CirRNA Circ_0058063 has been proven as an oncogene in bladder cancer, while its involvement in esophageal squamous-cell carcinomas (ESCC) is unknown. This study aimed to investigate the role of Circ_0058063 in ESCC. Methods:Paired ESCC and non-tumor tissues were collected from ESCC patients and gene express...

journal_title：Journal of thoracic disease

authors： Zheng Y,Chen Y,Jiang H,Zhang H,Wang H,Xu J,Yu Z

更新日期：2020-03-01 00:00:00

abstract：:Peripheral lung nodule evaluation represents a clinical challenge. Given that many nodules will be incidentally found with lung cancer screening following the publication of the National Lung Screening Trial (NLST), the goal is to find an accurate, safe and minimally-invasive diagnostic modality to biopsy the concerni...

journal_title：Journal of thoracic disease

authors： Arias S,Yarmus L,Argento AC

更新日期：2015-12-01 00:00:00

abstract：:The medical management of bronchiectasis includes confirming the diagnosis of the disease, evaluating the patient for possible underlying etiologies and then properly assessing the patient for appropriate therapies. Patients with bronchiectasis are heterogeneous and a personalized approach to each patient is needed in...

journal_title：Journal of thoracic disease

authors： O'Donnell AE

更新日期：2018-10-01 00:00:00

abstract：:This case report illustrates a patient who underwent supra-annular mechanical aortic valve replacement then suffered from prosthesis dysfunction, increasing pressure gradient with aortic valve. She was successfully underwent aortic valve re-replacement, sub-annular pannus removing and aortic annulus enlargement proced...

journal_title：Journal of thoracic disease

authors： Xu Y,Ye X,Li Z,Zhao Q

更新日期：2018-04-01 00:00:00

abstract：:Emphysema causes significant morbidity and mortality, incurring both financial and psychosocial costs. Alternatives to medical therapy and surgical lung volume reduction surgery (LVRS) have increased interest in bronchoscopic techniques. Bronchoscopic lung volume reduction (BLVR) is still in its infancy and additional...

journal_title：Journal of thoracic disease

authors： Ramaswamy A,Puchalski J

更新日期：2018-04-01 00:00:00

abstract：Background:Bronchiolitis obliterans syndrome (BOS) is a rare, progressive and irreversible airway disease associated with significant mortality after allogeneic hematopoietic stem-cell transplantation (HSCT). In this study, we investigated the therapeutic effect of high-dose budesonide/formoterol (320/9 µg bid) in pati...

journal_title：Journal of thoracic disease

authors： Kim KH,Lee J,Kim HJ,Lee S,Kim YJ,Lee JH,Rhee CK

更新日期：2020-08-01 00:00:00

abstract：Background:The bibliometric analysis has been performed on several topics in critical care medicine (CCM) focusing on top 100 cited articles, but the analysis on CCM literature as a whole is missing. The present study aimed to perform a complete bibliometric analysis in the field of CCM. Methods:An electronic search o...

journal_title：Journal of thoracic disease

authors： Zhang Z,Van Poucke S,Goyal H,Rowley DD,Zhong M,Liu N

更新日期：2018-04-01 00:00:00

abstract：:Lung transplantation is the gold standard therapy for patients with end-stage lung disease. The use of the lung allocation score (LAS) has permitted improved allocation of scarce pulmonary allografts. Recently, Crawford et al. examined the experience in the United States in lung transplantation in candidates with the ...

journal_title：Journal of thoracic disease

authors： Mulvihill MS,Hartwig MG,Daneshmand MA

更新日期：2017-09-01 00:00:00

abstract：:Optimal exposure of the mitral valve is paramount in minimally invasive surgery (MIS) and a prerequisite for successful mitral valve repair or replacement. We report the concept of a new left atrial retractor (Karl Storz GmbH, Tuttlingen, Germany) dedicated to MIS. The effectiveness of the device was evaluated in a pr...

journal_title：Journal of thoracic disease

authors： Greco E,Rose D,Irace F,Frati G

更新日期：2016-12-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) associates with several extra-pulmonary effects. Muscle dysfunction and wasting is one of the most prominent extra-pulmonary effects and contributes to exercise limitation and health related quality of life (HRQoL), morbidity as well as mortality. The loss of muscle mass is...

journal_title：Journal of thoracic disease

authors： Lakhdar R,Rabinovich RA

更新日期：2018-05-01 00:00:00

abstract：Background:Esophageal squamous cell carcinoma (ESCC) as the main subtype of esophageal cancer (EC) is a leading cause of cancer-related death worldwide. Despite advances in early diagnosis and clinical management, the long-term survival of ESCC patients remains disappointing, due to a lack of full understanding of the ...

journal_title：Journal of thoracic disease

authors： Hu J,Li R,Miao H,Wen Z

更新日期：2020-06-01 00:00:00

abstract：:This video demonstrated a performance of uniportal video-assisted thoracoscopic surgery (VATS) right upper lobectomy with systemic lymphadenectomy. The patient had a malignant mass in his right upper lobe. The operator took a posterior to anterior approach to dissection the right upper lobe, the adjacent structures we...

journal_title：Journal of thoracic disease

authors： Han DP,Xiang J,Li HC,Hang JB

更新日期：2016-08-01 00:00:00

abstract：Background:Assessment of serum extracellular matrix (ECM) metalloproteinase MMP-2 and tissue inhibitor of matrix metalloproteinase TIMP-2 concentrations in non-small cell lung carcinoma (NSCLC) patients considering TNM staging. Assessment of the prognostic value of MMP-2 and TIMP-2 concentrations in NSCLC patients. Me...

journal_title：Journal of thoracic disease

authors： Drzewiecka-Jędrzejczyk M,Wlazeł R,Terlecka M,Jabłoński S

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:For patients diagnosed with locally advanced esophageal cancer, neoadjuvant therapy followed by surgery is the most common approach. However, randomized trials resulted in inconsistent conclusions. We conducted this retrospective study to evaluate the influence of neoadjuvant therapy on postoperative events ...

journal_title：Journal of thoracic disease

authors： Lin D,Ma L,Ye T,Pan Y,Shao L,Song Z,Jiang S,Chen H,Xiang J

更新日期：2017-02-01 00:00:00

abstract：Background:Endoscopic thoracic sympathectomy (ETS) has not been widely adopted for treating craniofacial hyperhidrosis (CFH) due to its known postoperative complication, compensatory hyperhidrosis (CH). In this study, we evaluated whether the autonomic nerve analysis data via pre-ETS heart rate variability (HRV) test c...

journal_title：Journal of thoracic disease

authors： Moon DH,Kang DY,Lee HS,Lee JW,Lee YJ,Lee S

更新日期：2020-05-01 00:00:00

abstract：Background:In 2006, the Global Alliance against Chronic Respiratory Diseases (GARD) was established. The GARD strategy is based mainly on activities aimed at implementing preventive tasks at a local and global level. In Poland, the National Health Program (NHP) is the strategic document describing the tasks of governme...

journal_title：Journal of thoracic disease

authors： Raciborski F,Samoliński B,Krzych-Fałta E,Grąbczewska A,Furman F,Bieszczad M,Morkisz P,Witkowska P,Bousquet J,Gujski M

更新日期：2018-09-01 00:00:00

abstract：Background:Postoperative air leaks are the most common complication after a pulmonary resection. There is no data in the literature comparing the traditional and digital chest drainage system after a robotic-assisted pulmonary lobectomy. Methods:This was a retrospective, correlational study. Medical records from 182 e...

journal_title：Journal of thoracic disease

authors： Jacobsen K,Talbert S,Boyer JH

更新日期：2019-12-01 00:00:00

abstract：:Accurate determination of the diagnosis and the stage of lung cancer play a critical role to ensure that patients are provided the optimal treatment. However, the process is usually beyond complex. Early studies have suggested lymph nodes (LNs) >1.0 cm in size on computed tomography (CT) are considered as metastatic n...

journal_title：Journal of thoracic disease

authors： Xia Y,Zhang B,Zhang H,Li W,Wang KP,Shen H

更新日期：2015-12-01 00:00:00

abstract：Backgrounds:Invasive adenocarcinoma subtypes are known to be associated with prognosis; however, the underlying reason remains unclear. To find out the reason, we investigated the possible influence of lymph node (LN) involvement by the constituent histologic subtypes in the tumor and clarified the different prognosis ...

journal_title：Journal of thoracic disease

authors： Park JK,Kim JJ,Moon SW,Lee KY

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:The axillary vein is an easily accessible vessel that can be used for ultrasound-guided central vascular access and offers an alternative to the internal jugular and subclavian veins. The objective of this study was to identify which transducer orientation, longitudinal or transverse, is better for imaging t...

journal_title：Journal of thoracic disease

authors： He YZ,Zhong M,Wu W,Song JQ,Zhu DM

更新日期：2017-04-01 00:00:00

abstract：:Navigation bronchoscopy has reached a new horizon in its evolution. Combining with real-time imaging modalities, such as cone-beam computed tomography (CBCT) and augmented fluoroscopy (AF), navigation success can finally be confirmed with high degree of accuracy in real-time. With utilization of this modality, additio...

journal_title：Journal of thoracic disease

authors： Cheng GZ,Liu L,Nobari M,Miller R,Wahidi M

更新日期：2020-06-01 00:00:00