The role of PET/CT in the modern treatment of Hodgkin lymphoma.

Abstract:

:Classical Hodgkin Lymphoma is distinguished from other lymphomas by its peculiar biology and heterogeneous chemosensitivity. Most of the patients respond to the standard first-line treatment and are cured, however, in selected cases, the disease relapses or remains primarily refractory. Among predictive/prognostic factors 18FDG positron emission tomography (PET), fully integrated with computed tomography (PET/CT) proved to be extremely useful in identifying patients with poor prognosis at the time of diagnosis, during and at the end of treatment. The aim of this review is to present the current role of PET/CT in cHL at staging, interim and end of therapy assessment and its ability to guide treatment with a response- and risk-adapted strategy in clinical practice. Finally, quantitative PET measurement and the concurrent use of PET with selected biomarkers are discussed.

journal_name

Cancer Treat Rev

journal_title

Cancer treatment reviews

authors

Zaucha JM,Chauvie S,Zaucha R,Biggii A,Gallamini A

doi

10.1016/j.ctrv.2019.06.002

subject

Has Abstract

pub_date

2019-07-01 00:00:00

pages

44-56

eissn

0305-7372

issn

1532-1967

pii

S0305-7372(19)30080-5

journal_volume

77

pub_type

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