Sex ratios at birth vary with environmental harshness but not maternal condition.

abstract：:Rheumatoid arthritis (RA) is an autoimmune disease characterized by progressive immune-mediated joint deterioration. Current treatments are not antigen specific and are associated with various adverse. We have previously demonstrated that tolerogenic dendritic cells (Tol-DC) are potent antigen-specific immune regulato...

journal_title：Scientific reports

authors： Li R,Zhang Y,Zheng X,Peng S,Yuan K,Zhang X,Min W

更新日期：2017-02-23 00:00:00

abstract：:Although cisplatin plays a central role in cancer chemotherapy, the mechanisms of cell response to this drug have been unexplored. The present study demonstrates the relationships between the intracellular pH (pHi), cell bioenergetics and the response of cervical cancer to cisplatin. pHi was measured using genetically...

journal_title：Scientific reports

authors： Shirmanova MV,Druzhkova IN,Lukina MM,Dudenkova VV,Ignatova NI,Snopova LB,Shcheslavskiy VI,Belousov VV,Zagaynova EV

更新日期：2017-08-21 00:00:00

abstract：:Mathematical models of metabolism from bacterial systems biology have proven their utility across multiple fields, for example metabolic engineering, growth phenotype simulation, and biological discovery. The usefulness of the models stems from their ability to compute a link between genotype and phenotype, but their ...

journal_title：Scientific reports

authors： Aziz RK,Monk JM,Lewis RM,In Loh S,Mishra A,Abhay Nagle A,Satyanarayana C,Dhakshinamoorthy S,Luche M,Kitchen DB,Andrews KA,Fong NL,Li HJ,Palsson BO,Charusanti P

更新日期：2015-11-04 00:00:00

abstract：:In community ecology, it is important to understand the distribution of communities along environmental and spatial gradients. However, it is common for the residuals of models investigating those relationships to be very high (> 50%). It is believed that species' intrinsic characteristics such as rarity can contribut...

journal_title：Scientific reports

authors： Brasil LS,Vieira TB,Andrade AFA,Bastos RC,Montag LFA,Juen L

更新日期：2020-11-13 00:00:00

abstract：:Leaf traces are important structures in higher plants that connect leaves and the stem vascular system. The anatomy and emission pattern of leaf traces are well studied in extant vascular plants, but remain poorly understood in fossil lineages. We quantitatively analysed the leaf traces in the late Permian conifer Nin...

journal_title：Scientific reports

authors： Wei HB,Feng Z,Yang JY,Chen YX,Shen JJ,He XY

更新日期：2015-07-22 00:00:00

abstract：:A novel eco-friendly procedure was developed to produce safer, stable and highly pure zinc oxide nanoparticles (ZnO NPs) using microalgae Chlorella extract. The ZnO NPs were synthesized simply using zinc nitrate and microalgae Chlorella extract which conducted at ambient conditions. In this recipe, microalgae Chlorell...

journal_title：Scientific reports

authors： Khalafi T,Buazar F,Ghanemi K

更新日期：2019-05-03 00:00:00

abstract：:The precision prediction of peptide retention time (RT) plays an increasingly important role in liquid chromatography-tandem mass spectrometry (LC-MS/MS) based proteomics. Owing to the high reproducibility of liquid chromatography, RT prediction provides promising information for both identification and quantification...

journal_title：Scientific reports

authors： Lu W,Liu X,Liu S,Cao W,Zhang Y,Yang P

更新日期：2017-03-17 00:00:00

abstract：:Copper complexes with potent anti-tumor effect have been extensively developed. Most investigations of their modes of action focused on the biomolecular targets but not the signal transduction between target binding and cell death. We have previously shown that the cytotoxic complex pyridine(2,4-dihydroxybenzaldehyde ...

journal_title：Scientific reports

authors： Goh YY,Yan YK,Tan NS,Goh SA,Li S,Teoh YC,Lee PP

更新日期：2016-11-14 00:00:00

abstract：:Biomass waste products from green algae have recently been given new life, as these polysaccharides have potential applications in industry, agriculture, and medicine. One such polysaccharide group called ulvans displays many different, potentially useful properties that arise from their structural versatility. Hence,...

journal_title：Scientific reports

authors： Melcher RL,Neumann M,Fuenzalida Werner JP,Gröhn F,Moerschbacher BM

更新日期：2017-03-22 00:00:00

abstract：:Marine sponges are early-branching, filter-feeding metazoans that usually host complex microbiomes comprised of several, currently uncultivatable symbiotic lineages. Here, we use a low-carbon based strategy to cultivate low-abundance bacteria from Spongia officinalis. This approach favoured the growth of Alphaproteoba...

journal_title：Scientific reports

authors： Karimi E,Keller-Costa T,Slaby BM,Cox CJ,da Rocha UN,Hentschel U,Costa R

更新日期：2019-02-13 00:00:00

abstract：:The spine flexibility creates one of the most significant challenges to proper positioning in radiation therapy of head and neck cancers. Even though existing immobilization techniques can reduce the positioning uncertainty, residual errors (2-3 mm along the cervical spine) cannot be mitigated by single translation-ba...

journal_title：Scientific reports

authors： Ostyn M,Wang S,Kim YS,Kim S,Yeo WH

更新日期：2019-10-07 00:00:00

abstract：:A fundamental strategy to enhance optical transmission through a continuous metallic film based on strong interference dominated by interface phase shift is developed. In a metallic film coated with a thin semiconductor film, both transmission and absorption are simultaneously enhanced as a result of dramatically redu...

journal_title：Scientific reports

authors： Li Q,Du K,Mao K,Fang X,Zhao D,Ye H,Qiu M

更新日期：2016-07-12 00:00:00

abstract：:Anatase TiO2 has been suggested as a potential sodium anode material, but the low electrical conductivity of TiO2 often limits the rate capability, resulting in poor electrochemical properties. To address this limitation, we propose graphene-wrapped anatase TiO2 nanofibers (rGO@TiO2 NFs) through an effective wrapping ...

journal_title：Scientific reports

authors： Yeo Y,Jung JW,Park K,Kim ID

更新日期：2015-09-10 00:00:00

abstract：:We analyze the symmetry and topological features of a family of materials closely related to penta-graphene, derived from it by adsorption or substitution of different atoms. Our description is based on a novel approach, called topological quantum chemistry, that allows to characterize the topology of the electronic b...

journal_title：Scientific reports

authors： Bravo S,Correa J,Chico L,Pacheco M

更新日期：2019-09-04 00:00:00

abstract：:The serum macrophage inhibitory cytokine-1 (MIC-1) levels are elevated in some inflammatory conditions and cancers. We thus compared the levels of biliary and serum MIC-1 and conventional tumour markers between 23 biliary tract cancer (BTC) patients (malignant group) and 29 benign biliary disease patients (benign grou...

journal_title：Scientific reports

authors： Sugimoto M,Takagi T,Konno N,Suzuki R,Asama H,Watanabe K,Nakamura J,Waragai Y,Kikuchi H,Takasumi M,Sato Y,Hikichi T,Ohira H

更新日期：2017-08-23 00:00:00

abstract：:The natural alkaloid berberine has several pharmacological properties and recently received attention as a potential anticancer agent. In this work, we investigated the molecular mechanisms underlying the anti-tumor effect of berberine on glioblastoma U343 and pancreatic carcinoma MIA PaCa-2 cells. Human dermal fibrob...

journal_title：Scientific reports

authors： Agnarelli A,Natali M,Garcia-Gil M,Pesi R,Tozzi MG,Ippolito C,Bernardini N,Vignali R,Batistoni R,Bianucci AM,Marracci S

更新日期：2018-07-13 00:00:00

abstract：:Polymersome nanoparticles (PMs) are attractive candidates for spatio-temporal controlled delivery of therapeutic agents. Although many studies have addressed cellular uptake of solid nanoparticles, there is very little data available on intracellular release of molecules encapsulated in membranous carriers, such as po...

journal_title：Scientific reports

authors： Scarpa E,Bailey JL,Janeczek AA,Stumpf PS,Johnston AH,Oreffo RO,Woo YL,Cheong YC,Evans ND,Newman TA

更新日期：2016-07-11 00:00:00

abstract：:Sepsis is an infection-induced systemic inflammatory syndrome and a major cause of death for critically ill patients. Here, we examined whether the absence of Sprouty-related EVH1-domain-containing protein 2 (Spred2), a negative regulator of the Ras/Raf/ERK/MAPK pathway, influences host defense against polymicrobial s...

journal_title：Scientific reports

authors： Itakura J,Sato M,Ito T,Mino M,Fushimi S,Takahashi S,Yoshimura T,Matsukawa A

更新日期：2017-10-09 00:00:00

abstract：:Acute kidney disease (AKD) is a state between acute kidney injury (AKI) and chronic kidney disease (CKD), but the prognosis of AKD is unclear and there are no risk-prediction tools to identify high-risk patients. 2,556 AKI patients were selected from 277,898 inpatients of three affiliated hospitals of Central South Un...

journal_title：Scientific reports

authors： Xiao YQ,Cheng W,Wu X,Yan P,Feng LX,Zhang NY,Li XW,Duan XJ,Wang HS,Peng JC,Liu Q,Zhao F,Deng YH,Yang SK,Feng S,Duan SB

更新日期：2020-09-24 00:00:00

abstract：:WRINKLED1 (WRI1), an APETALA2 (AP2)-type transcription factor, has been shown to be required for the regulation of carbon partitioning into fatty acid (FA) synthesis in plant seeds. To our knowledge, the regulatory network of WRI1 remains unknown in Prunus sibirica kernel (PSK), a novel woody biodiesel feedstock in Ch...

journal_title：Scientific reports

authors： Deng S,Mai Y,Shui L,Niu J

更新日期：2019-02-25 00:00:00

abstract：:Osteogenesis is categorized into two groups based on developmental histology, intramembranous and endochondral ossification. The role of blood vessels during endochondral ossification is well known, while their role in intramembranous ossification, especially the intertissue pathway, is poorly understood. Here, we dem...

journal_title：Scientific reports

authors： Uemura M,Nagasawa A,Terai K

更新日期：2016-06-07 00:00:00

abstract：:Bimetallic Pd1-x Pt x solid-solution nanoparticles (NPs) display charging/discharging of hydrogen gas, which has relevance for fuel cell technologies; however, the constituent elements are immiscible in the bulk phase. We examined these material systems using high-energy synchrotron X-ray diffraction, X-ray absorption...

journal_title：Scientific reports

authors： Kumara LSR,Sakata O,Kobayashi H,Song C,Kohara S,Ina T,Yoshimoto T,Yoshioka S,Matsumura S,Kitagawa H

更新日期：2017-11-06 00:00:00

abstract：:Fully elucidating the molecular mechanisms of non-coding RNAs (ncRNAs), including micro RNAs (miRNAs) and long non-coding RNAs (lncRNAs), underlying hepatocarcinogenesis is challenging. We characterized the expression profiles of ncRNAs and constructed a regulatory mRNA-lncRNA-miRNA (MLMI) network based on transcripto...

journal_title：Scientific reports

authors： Tang X,Feng D,Li M,Zhou J,Li X,Zhao D,Hao B,Li D,Ding K

更新日期：2019-11-06 00:00:00

abstract：:Our study aimed to compare the ability of anthropometric obesity indices to predict MetS and to determine the sex-specific optimal cut-off values for MetS among Malaysian vegetarians. Body weight, height, waist circumference (WC), blood pressure (BP), fasting venous blood sample were collected from 273 vegetarians in ...

journal_title：Scientific reports

authors： Ching YK,Chin YS,Appukutty M,Gan WY,Chan YM

更新日期：2020-11-30 00:00:00

abstract：:Pediatric obstructive sleep-disordered breathing is associated with growth retardation, but also with obesity that has a tendency to persist following treatment. We investigated the effect of upper airways obstruction (AO) and of obstruction removal (OR) in juvenile rats on gut-derived ghrelin and related hypothalamic...

journal_title：Scientific reports

authors： Assadi MH,Shknevsky E,Segev Y,Tarasiuk A

更新日期：2017-06-02 00:00:00

abstract：:We report, for the first time, that the energy of femtosecond optical laser pulses, E, with relativistic intensities I > 10(21)  W/cm(2) is efficiently converted to X-ray radiation, which is emitted by "hot" electron component in collision-less processes and heats the solid density plasma periphery. As shown by direct...

journal_title：Scientific reports

authors： Faenov AY,Colgan J,Hansen SB,Zhidkov A,Pikuz TA,Nishiuchi M,Pikuz SA,Skobelev IY,Abdallah J,Sakaki H,Sagisaka A,Pirozhkov AS,Ogura K,Fukuda Y,Kanasaki M,Hasegawa N,Nishikino M,Kando M,Watanabe Y,Kawachi T,Masuda S

更新日期：2015-09-02 00:00:00

abstract：:Periodontal ligament stem cells (PDLSCs) are a major source of mesenchymal stem cells (MSCs) in adults and are effective for tissue engineering, like promoting angiogenesis and bone regeneration. CXCL12 has been reported to be involved in the recruitment and engraftment of MSCs in wound sites. However, whether CXCL12 ...

journal_title：Scientific reports

authors： Zhang L,Zhou Y,Sun X,Zhou J,Yang P

更新日期：2017-08-31 00:00:00

abstract：:Secondary ion mass spectrometry is an excellent technique of analytical chemistry, where primary ions sputter a solid sample generating the secondary ions which are determined. Although the ion yield is inherently low, it can be enhanced by using a post-ionization of sputtered neutral species. Our novel approach integ...

journal_title：Scientific reports

authors： Lorenc D,Jerigova M,Stupavska M,Velic D

更新日期：2017-07-20 00:00:00

abstract：:The mitochondrial genome (mt genome) provides important information for understanding molecular evolution and phylogenetics. As such, the two complete mt genomes of Ampelophaga rubiginosa and Rondotia menciana were sequenced and annotated. The two circular genomes of A. rubiginosa and R. menciana are 15,282 and 15,636...

journal_title：Scientific reports

authors： Xin ZZ,Yu Liu,Zhu XY,Wang Y,Zhang HB,Zhang DZ,Zhou CL,Tang BP,Liu QN

更新日期：2017-07-26 00:00:00

abstract：:Speaking involves coordination of multiple neuromotor systems, including respiration, phonation and articulation. Developing non-invasive imaging methods to study how the brain controls these systems is critical for understanding the neurobiology of speech production. Recent models and animal research suggest that reg...

journal_title：Scientific reports

authors： Correia JM,Caballero-Gaudes C,Guediche S,Carreiras M

更新日期：2020-03-11 00:00:00