Abstract:
OBJECTIVES:To evaluate the effect of bovine colostrum (BC) on the treatment of children with acute diarrhea attending the outpatient clinic. METHODS:This double-blind randomized controlled trial was conducted on 160 children with diarrhea; 80 cases were randomly treated with BC group and 80 cases randomly received placebo (placebo group). All cases were investigated for bacterial causes of diarrhea (Salmonella spp, Shigella spp, diarrheagenic E. coli (DEC), Campylobacter spp., and Vibrio cholerae) as well as for Rotavirus antigen in stool. RESULTS:After 48 h, the BC group had a significantly lower frequency of vomiting, diarrhea and Vesikari scoring compared with the placebo group (p = 0.000, p = 0.000, p = 0.000, respectively), whether it was due to Rotavirus or E. coli infection. CONCLUSIONS:BC is effective in the treatment of acute diarrhea and can be considered as adjuvant therapy in both viral and bacterial diarrhea to prevent diarrhea-related complications.
journal_name
J Trop Pediatrjournal_title
Journal of tropical pediatricsauthors
Barakat SH,Meheissen MA,Omar OM,Elbana DAdoi
10.1093/tropej/fmz029subject
Has Abstractpub_date
2020-02-01 00:00:00pages
46-55issue
1eissn
0142-6338issn
1465-3664pii
5511643journal_volume
66pub_type
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