Abstract:
:In a previous study of rachitic children in Jos, Nigeria we concluded that inadequate dietary intake of calcium was the primary contributing factor to the development of their rickets. The objective of the present study was to determine the effect of calcium supplementation in 10 children with radiographically and biochemically proven rickets from the same geographical area. Rachitic children were provided with calcium supplements of 1000 mg/day for a period of 3 months. Serum and urine samples were obtained at baseline and at 24 hours, 1 week, 4 weeks, and 12 weeks after initiation of supplementation. Serum calcium, phosphorus, alkaline phosphatase, intact parathyroid hormone, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D were measured at each time point. Dietary recalls obtained at two separate times were used to estimate usual daily intakes of calcium and phosphorus. Ten non-rachitic age-matched controls from the same geographical area were recruited for comparison. Nine of 10 rachitic subjects had radiographic evidence of healing after 3 months of calcium therapy. Although serum calcium concentrations returned to control levels, other biochemical data indicated that the rickets of these subjects may have been multifactorial in aetiology, pointing to a possible defect in the synthesis of 25-hydroxyvitamin D.
journal_name
J Trop Pediatrjournal_title
Journal of tropical pediatricsauthors
Thacher T,Glew RH,Isichei C,Lawson JO,Scariano JK,Hollis BW,VanderJagt DJdoi
10.1093/tropej/45.4.202keywords:
subject
Has Abstractpub_date
1999-08-01 00:00:00pages
202-7issue
4eissn
0142-6338issn
1465-3664journal_volume
45pub_type
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journal_title:Journal of tropical pediatrics
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abstract::This study, which was carried out in the Jos Plateau in Nigeria, analysed the changes in growth and body composition that occurred among 17 male and 13 female Fulani children (aged 4-13 years) in the 7-month period which followed their displacement from their homes into a temporary camp due to ethnic/religious violenc...
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abstract::A total of 220 enteroadherent Escherichia coli were identified from 729 Egyptian children with diarrhea using the HEp-2 adherence assay. Enteropathogenic E.coli (EPEC = 38) was common among children <6 months old and provoked vomiting, while diffuse-adhering E.coli (DAEC = 109) induced diarrheal episodes of short dura...
journal_title:Journal of tropical pediatrics
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journal_title:Journal of tropical pediatrics
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abstract:BACKGROUND:Early data regarding the outcome of human immunodeficiency virus (HIV)-infected children in paediatric intensive care units (PICU) suggested mortality as high as 100%. Recent studies report mortality of 38%. Survival depends on the indication for admission. OBJECTIVES:To describe the prevalence, duration of...
journal_title:Journal of tropical pediatrics
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journal_title:Journal of tropical pediatrics
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journal_title:Journal of tropical pediatrics
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journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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journal_title:Journal of tropical pediatrics
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journal_title:Journal of tropical pediatrics
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更新日期:2001-10-01 00:00:00
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journal_title:Journal of tropical pediatrics
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更新日期:2014-08-01 00:00:00
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journal_title:Journal of tropical pediatrics
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更新日期:1992-02-01 00:00:00
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journal_title:Journal of tropical pediatrics
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journal_title:Journal of tropical pediatrics
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journal_title:Journal of tropical pediatrics
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journal_title:Journal of tropical pediatrics
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journal_title:Journal of tropical pediatrics
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journal_title:Journal of tropical pediatrics
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abstract::Of 511 young (1-19 years of age) Jamaicans sampled for IgG antibodies to Toxoplasma by the ELISA method, there was an overall prevalence of 45 per cent. Seropositivity ranged from 24-26 per cent in the 2-year-olds, up to 54 per cent in the 5-9-year-olds. There was no significant difference in prevalence between the se...
journal_title:Journal of tropical pediatrics
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abstract::The composition (total solids, total protein, casein, coagulable proteins, lactose, fat, and ash) and mineral content (calcium, phosphorus, sodium, potassium, magnesium, zinc, and copper) of human milk was estimated longitudinally for the first year of lactation. Concentration of various nutrients, except zinc and cop...
journal_title:Journal of tropical pediatrics
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更新日期:1989-06-01 00:00:00
abstract:Objectives:To evaluate pediatric intensive care unit (PICU) needs, outcome and predictors of mortality in post-neonatal tetanus. Materials and methods:Review of 30 consecutive post-neonatal tetanus cases aged 1 months to 12 years admitted to a PICU in north India over a period of 10 years (January 2006 to December 201...
journal_title:Journal of tropical pediatrics
pub_type: 杂志文章
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abstract::Serum immunoglobulin E (IgE) and absolute eosinophil count (AEC) were assayed in 48 children with idiopathic nephrotic syndrome and 20 controls. The mean serum IgE (p < 0.001) and AEC (p < 0.05) were significantly raised in active nephrotic syndrome compared with controls. The mean values of IgE and AEC in nephrotic p...
journal_title:Journal of tropical pediatrics
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