Abstract:
BACKGROUND:Published data indicate that 20-40% of patients undergo breast conservation treatment (BCT) in Asia, which is below an indicative benchmark of 50%. With an increasing body of evidence suggesting that BCT might be associated with improved survival outcomes, it is exigent to increase BCT utilization. This study was therefore undertaken to evaluate BCT rates for women presenting with symptomatic breast cancer and potential for de-escalation of surgical treatment. METHODS:All patients who presented with symptomatic tumours and underwent surgical treatment at the authors' healthcare facility between January 2009 and December 2011 were included in this retrospective study. Standard wide excision was performed to achieve clear margins and reasonable cosmetic outcomes for BCT-eligible patients. Oncoplastic techniques such as therapeutic mammoplasty or volume replacement with flaps were not employed. RESULTS:A total of 116 women presented with symptomatic breast cancer. The majority (92.2%) were Asian. Mean age at diagnosis was 48.3 years and mean tumour size was 23.4 mm. Ninety-five patients (81.9%) underwent BCT. Of the 22 patients, 13 (59%) who underwent neoadjuvant chemotherapy had sufficient tumour size downstaging to successfully undergo BCT instead of mastectomy. CONCLUSION:It is possible for more than 80% of Asian women with symptomatic breast malignancies to undergo BCT, with the appropriate use of neoadjuvant medical therapy and surgical techniques. As increasing data indicate improved survival with BCT, this should be offered as the treatment of choice.
journal_name
ANZ J Surgjournal_title
ANZ journal of surgeryauthors
Tan MPC,Sitoh YYdoi
10.1111/ans.15084subject
Has Abstractpub_date
2019-05-01 00:00:00pages
529-535issue
5eissn
1445-1433issn
1445-2197journal_volume
89pub_type
杂志文章abstract:BACKGROUND:Readability indices have been developed based on sentence length and the use of long words. One such measure is the Reading Ease Scale developed by Rudolf Flesch. Texts that are easy to read have high scores: texts with scores below 30 are similar to legal contracts. This study uses Flesch scores to evaluate...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03651.x
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:Cruciferous vegetable consumption is inversely related to the incidence of prostate cancer. We examined the effect of indole-3-carbinol (I3C) and of sulforaphane (constituents of cruciferous vegetables) on cell proliferation of a PC-3 prostate cancer cell line, in order to observe if an inhibitory effect mig...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-2197.2003.02652.x
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:Surgical decision-making tools may help surgeons achieve better outcomes by providing more personally relevant information to patients. This paper describes approaches to developing statistical tools capable of estimating the probability of morbidity and mortality after cardiovascular surgery. Our aim is to ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/j.1445-2197.2010.05644.x
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:In the present paper we describe the presentation and management of ductal carcinoma in situ (DCIS) of the breast in women in Australia in 1995. This representative, national data set provides a historical comparator for studies examining DCIS management that follow. METHODS:Surgeons identified by populatio...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-2197.2002.02532.x
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:Thoracic Outlet Syndrome (TOS) refers to compression of the neurovascular structures in the region between the scalene muscles and the first rib, or by anatomical abnormalities such as cervical rib, fibrous bands and other variations in the scalene musculature. METHODS:Our experience with 63 consecutive ope...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2004.03016.x
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:Trapidil has various properties including vasodilatation, inhibition of lipid peroxidation and platelet aggregation as well as, and reduction of, the inflammatory response to injury. The aim of the present study was to investigate the effects of trapidil on dexamethasone-impaired colonic anastomotic healing ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-2197.2003.02683.x
更新日期:2003-11-01 00:00:00
abstract:BACKGROUND:This study investigates case cancellations on the intended day of surgery (DOS) at a paediatric hospital in Melbourne, Australia. The hospital in Melbourne treats over 32 000 inpatients annually and handles both elective and emergency cases. METHODS:The data for this paper were collected over a period of 12...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2009.05019.x
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Human facial allotransplantation (FA) is a testament to the impressive progress, which was and is still happening in the field of transplantation medicine and reconstructive surgery. Like every pioneering treatment option, FA faces both the clinicians' and public opinion with a huge amount of medical and psy...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/j.1445-2197.2009.05140.x
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to evaluate the correlation between serum albumin level change (ΔALB) and post-operative complications in patients with normal preoperative serum albumin after gastrectomy of gastric cancer. METHODS:A total of 193 patients undergoing curative (R0) gastrectomy from September 201...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15363
更新日期:2019-07-01 00:00:00
abstract::This article was presented at the conjoint CSSA and RACS (colorectal section) spring meeting Queensland, Australia, September 2004. The adenoma-carcinoma sequence describes a succession of events from polypoid adenoma to colorectal cancer. However, this model only accounts for up to two-thirds of colorectal cancers. T...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/j.1445-2197.2006.03847.x
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Trimodality therapy (TMT; extrapleural pneumonectomy (EPP), chemotherapy and radiation therapy) offers the potential of optimal survival in selected patients with Brigham stage I-II epitheliod mesothelioma based on CT, MRI and PET scanning. We hypothesized that these scanning modalities were inadequate to ac...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2009.05060.x
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:The Consolidated Standards of Reporting Trials (CONSORT) Statement outlines acceptable ways of performing and reporting clinical trials. The objective of the present study was to identify evolving patterns in the methodological standards of surgical trials. METHODS:Compliance with 12 key standards from the ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2005.03554.x
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:In Australia, there has been a shift from the traditional 'on-call' surgical model to the 'acute surgical unit' (ASU) model to improve outcomes in acute general surgery. Using emergency appendicectomy as a standardized procedure, we aimed to identify the different patterns of care between these on-call struc...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.16558
更新日期:2021-01-18 00:00:00
abstract:BACKGROUND:Few studies have investigated the risk factors associated with developing intestinal stoma complications using appropriate multivariable methods. We aimed to determine the prevalence of, and risk factors for, stomal complications. METHODS:A retrospective, case-control methodology was used to investigate 12 ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13397
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Sentinel node biopsy is an accurate method for staging the axilla in early (small) breast cancers. However, data for the role of this technique for large breast cancers remain limited. METHOD:From the Royal Adelaide Hospital Sentinel Node database and the SNAC trial database, 100 subjects were identified wi...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12139
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Acute diverticulitis of the caecum and ascending colon is uncommon. Controversies abound as regards the optimal surgical treatment, ranging from appendectomy, diverticulectomy to right hemicolectomy. The aim of the present paper was to review treatment strategy followed by a critical appraisal. METHODS:The ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-1433.2001.2226.x
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:Open cholecystectomy is still a fairly frequently performed operation worldwide, and is used where laparoscopic surgery has failed or is contraindicated, and where some surgeons do not operate laparoscopically for technical reasons. In developing countries laparoscopic cholecystectomy is costly and is availa...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1440-1622.2001.02046.x
更新日期:2001-02-01 00:00:00
abstract:BACKGROUND:The aim of this study was to assess the value of fine-needle aspiration cytology (FNAC) as a preoperative evaluation for parotid tumours. METHODS:Prospectively collected data on 77 patients, collected on a parotid database, were retrospectively analysed. Preoperative investigations were carried out and cyto...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2008.04651.x
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:Bisphosphonates (BPs) are widely used for the treatment of osteoporosis. Oversuppression of bone turnover with BPs may paradoxically limit the reserve capacity of bone to heal. The aim of this review was to study the predisposition of some patients to delayed/non-union of upper limb fractures associated with...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/ans.12536
更新日期:2014-04-01 00:00:00
abstract::To the ancient Greeks, physical exercise was an essential part of life, especially during adolescence and young adulthood. Long after the end of the Classical Greek era, Roman conquest brought a shift towards martial training, increased professionalism in athletic competition and a weak strand of restorative gymnastic...
journal_title:ANZ journal of surgery
pub_type: 历史文章,杂志文章
doi:10.1111/j.1445-2197.2009.05149.x
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:The aim of this study was to identify factors associated with rupture in elderly patients with acute appendicitis. METHODS:The medical records of 601 consecutive patients >60 years of age with acute appendicitis between 1995 and 2005 were retrospectively reviewed. Historical, clinical and laboratory factors...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2007.04182.x
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:The technical proficiency of a surgeon is intricately linked to training and experience. Reduction in working hours, decreased operating time and ethical imperatives to protect patients have all resulted in a decrease in hands-on experience. The introduction of laparoscopic procedures has also decreased trai...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15258
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:The aim of this study was to review the discrepancies in Gleason scores (GS) of prostate biopsies and radical prostatectomy specimens and the effects of multiple-needle biopsies on scoring accuracy. METHODS:One hundred patients who had undergone consecutive radical prostatectomies (RP) between January 2004 ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2007.04054.x
更新日期:2007-05-01 00:00:00
abstract::Bleeding related to rectal varices associated with portal hypertension is rare but life-threatening, and requires prompt treatment. We reviewed the literature for patients with this complex presentation and current recommendations, and commented on a case at our institution of a 68-year-old man with Child-Pugh B alcoh...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/ans.15982
更新日期:2020-05-14 00:00:00
abstract:BACKGROUND:Improved life-expectancies have seen increased rates of older patients undergoing surgery worldwide. These patients are at increased risk of post-operative complications. Australian evidence is limited regarding the association between age and post-operative outcomes, especially rapid response calls (RRCs) a...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.14433
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Metabolic acidosis is frequently observed in perioperative patients, especially those who undergo major surgery. The aim of this study was to evaluate the factors related to post-operative metabolic acidosis and to attempt to identify the clinical effect of metabolic acidosis following major abdominal surger...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2012.06235.x
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:Previous studies have shown that children with isolated linear skull fractures have excellent clinical outcomes and low risk of surgery. We wish to identify other injury patterns within the spectrum of paediatric mild head injury, which need only conservative management. Children with low risk of evolving ne...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.14175
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Severe tracheal stenosis is a rare life-threatening condition that often requires early surgical intervention. The management of this anomaly has been associated with significant mortality and morbidity. We describe our experience with repair of this condition. METHODS:From 1986 to 2011, 20 patients underwe...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12132
更新日期:2014-10-01 00:00:00
abstract::The gastrocnemius muscle is versatile in flap repair of defects from anterior knee to lower leg. We describe a case of extensor reconstruction using an extended medial gastrocnemius myocutaneous flap. A medial gastrocnemius flap was raised distal to its musculotendinous insertion. At its point of rotation, it was anch...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03951.x
更新日期:2006-12-01 00:00:00
abstract:BACKGROUND:We aimed to document the anatomical variations of pulmonary fissures found during routine forensic autopsies. METHODS:A total of 256 pairs of lungs were investigated. Presence of any variant and accessory fissures was noted. RESULTS:Seventy-seven percent of the lungs had anatomical variations. In about 2/3...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15553
更新日期:2020-04-01 00:00:00