Discrepancies in Gleason scoring of prostate biopsies and radical prostatectomy specimens and the effects of multiple needle biopsies on scoring accuracy. A regional experience in Tamworth, Australia.

Abstract:

BACKGROUND:The aim of this study was to review the discrepancies in Gleason scores (GS) of prostate biopsies and radical prostatectomy specimens and the effects of multiple-needle biopsies on scoring accuracy. METHODS:One hundred patients who had undergone consecutive radical prostatectomies (RP) between January 2004 and May 2006 were reviewed retrospectively. Patient information including age, prebiopsy prostate-specific antigen levels, biopsy GS, RP GS and pathology details were recorded and compared. RESULTS:The concordance rate of biopsy GS and RP GS was found to be at 43%, with 46% of biopsy specimens being undergraded. Eleven per cent of the specimens were overgraded. The accuracy was fairly similar when specimens were reported by the same or different pathologists, at 42 and 44%, respectively. The accuracy of biopsy GS improved with increasing number of biopsies taken. CONCLUSION:There are significant discrepancies in Gleason scoring of biopsy and RP specimens, with a concordance rate of 43% and undergrading rate of 46%. Increasing the number of biopsies helps improve scoring accuracy. Clinicians and patients need to be mindful when deciding cancer treatment options, in view of these discrepancies.

journal_name

ANZ J Surg

journal_title

ANZ journal of surgery

authors

Ooi K,Samali R

doi

10.1111/j.1445-2197.2007.04054.x

subject

Has Abstract

pub_date

2007-05-01 00:00:00

pages

336-8

issue

5

eissn

1445-1433

issn

1445-2197

pii

ANS4054

journal_volume

77

pub_type

杂志文章
  • Functional and proteomic analysis of serum and cerebrospinal fluid derived from patients with traumatic brain injury: a pilot study.

    abstract:BACKGROUND:An enhanced fracture healing response has been reported in patients with traumatic brain injury (TBI). This has been attributed to circulating humoral factors that are thought to be proteins produced and released by the injured brain. However, these factors remain unknown. The aim of this study was to identi...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2010.05268.x

    authors: Cadosch D,Thyer M,Gautschi OP,Lochnit G,Frey SP,Zellweger R,Filgueira L,Skirving AP

    更新日期:2010-07-01 00:00:00

  • Fifteen-year groin hernia trends in Australia: the era of minimally invasive surgeons.

    abstract:BACKGROUND:Groin hernia repairs (GHRs) are among the commonest general surgical procedures in the Western population. The introduction of minimally invasive surgery has prompted the development of laparoscopic totally extraperitoneal and trans-abdominal preperitoneal hernia repairs. We aimed to determine the hernia tre...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.13899

    authors: Kevric J,Papa N,Toshniwal S,Perera M

    更新日期:2018-04-01 00:00:00

  • Appendicectomy at a children's hospital: what has changed over a decade?

    abstract:BACKGROUND:Appendicectomy remains the most common abdominal emergency procedure performed by surgeons. We reviewed appendicectomies for the calendar years 1999 and 2009 to assess any changes in the referral, presentation and management at a tertiary paediatric institution. METHODS:We performed a retrospective chart re...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2012.06168.x

    authors: Wilson BE,Cheney L,Patel B,Holland AJ

    更新日期:2012-09-01 00:00:00

  • Blood management in total hip replacement: an analysis of factors associated with allogenic blood transfusion.

    abstract:BACKGROUND:The aim of this study was to audit the blood transfusion practice throughout the Epworth Healthcare Hospitals for patients undergoing primary total hip replacement (THR). We determined if blood-saving techniques were having an impact on the risk of allogenic blood transfusion and which patients were at risk ...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.13048

    authors: Wong S,Tang H,de Steiger R

    更新日期:2015-06-01 00:00:00

  • Do we need to scan the whole neuraxis for coexistent abnormalities in children with surgically treated occult spinal dysraphism?

    abstract:BACKGROUND:Spina bifida occulta (SBO) is generally known as a benign isolated entity; however, there are ambiguous approaches for neuroaxial screening in cases of symptomatic SBO among institutions. This study aims to demonstrate the infrequency of cranial anomalies associated with symptomatic SBO and inquire the neces...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.15164

    authors: Börcek AÖ,Aslan A,Uçar M

    更新日期:2019-07-01 00:00:00

  • Optimization of perioperative care for colonic surgery: a review of the evidence.

    abstract::Enhanced recovery after surgery (ERAS) care pathways are becoming increasingly common in colonic surgery. ERAS is a combination of individual strategies that have been shown to be effective in improving care. In this article, we review the evidence surrounding core components of enhanced recovery care pathways for pat...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1111/j.1445-2197.2007.04350.x

    authors: Zargar-Shoshtari K,Hill AG

    更新日期:2008-01-01 00:00:00

  • Modified classification for adenocarcinoma of the gastro-oesophageal junction.

    abstract:BACKGROUND:Incidence of the gastro-oesophageal junction adenocarcinoma is increasing. Siewert's classification subdivides junctional adenocarcinomas anatomically. Cytokeratin (CK) 7 and 20 immunophenotypes differentiate Barrett's intestinal metaplasia (IM) from gastric IM. Comparing CK immunostaining with Siewert's cla...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2007.04147.x

    authors: Shearer CJ,Going JJ,Neilson LJ,Stuart RC

    更新日期:2007-07-01 00:00:00

  • Mastectomy flap design: the 'waisted teardrop' and a method to reduce the lateral fold.

    abstract:BACKGROUND:There are various methods to design mastectomy flaps but few are standardized. Lateral skin folds or 'dog ears' are a common, unsightly and uncomfortable consequence following a surgery in overweight patients. METHODS:We describe a simple technique for designing mastectomy flaps and a method to eliminate th...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2012.06046.x

    authors: Thomas R,Mouat C,King B

    更新日期:2012-05-01 00:00:00

  • Surgical procedures for melanoma in public and private New South Wales hospitals, 2001-2002.

    abstract:BACKGROUND:Evidence suggests that there is considerable variation in the types of procedures used to treat cancer. This variation may result in suboptimal or cost-ineffective care. The present study examined the variation in surgical treatment of melanoma before the establishment of a Melanoma Network that could promot...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2006.03717.x

    authors: Barton MB,Gabriel GS,Frommer MS,Holt PE,Thompson JF

    更新日期:2006-05-01 00:00:00

  • Solid pseudopapillary tumour of the pancreas.

    abstract:BACKGROUND:Solid pseudopapillary tumour of the pancreas is a rare pancreatic tumour that occurs predominantly in women, with very few cases reported in men. This is a tumour with low malignancy potential and surgical resection usually results in cure. METHODS:A retrospective review of our experience with solid pseudop...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1046/j.1445-2197.2003.t01-1-02634.x

    authors: Ng KH,Tan PH,Thng CH,Ooi LL

    更新日期:2003-06-01 00:00:00

  • Effects of fatigue on surgeon performance and surgical outcomes: a systematic review.

    abstract:BACKGROUND:Sleep deprivation and disturbances in circadian rhythms generally lead to poor performance, but is there a link in surgery? This review aimed to determine whether fatigue has an impact on surgeon performance or surgical outcomes. METHODS:Studies were identified by searching EMBASE, CINAHL, PubMed, The Cochr...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1111/j.1445-2197.2010.05642.x

    authors: Sturm L,Dawson D,Vaughan R,Hewett P,Hill AG,Graham JC,Maddern GJ

    更新日期:2011-07-01 00:00:00

  • Effects of early antiplatelet therapy after splenectomy with gastro-oesophageal devascularization.

    abstract:BACKGROUND:This study aimed to explore the effects of early antiplatelet therapy (APT) for portal vein thrombosis (PVT) in patients with cirrhotic portal hypertension after splenectomy with gastro-oesophageal devascularization. METHODS:We retrospectively analysed 139 patients who underwent splenectomy with gastro-oeso...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.14395

    authors: Zhou JB,Luo BY,Liu CW,Zhu F

    更新日期:2018-10-01 00:00:00

  • Appendix redux: a stone unturned.

    abstract::Recent advances in understanding of the biology of appendicitis are reviewed. Immunological aspects are discussed in the setting of a changing microbiome. Implications for practice are summarized. ...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1111/ans.16018

    authors: de Costa A

    更新日期:2020-06-08 00:00:00

  • Feasibility of day-care open cholecystectomy: evaluation in an inpatient model.

    abstract:BACKGROUND:Open cholecystectomy is still a fairly frequently performed operation worldwide, and is used where laparoscopic surgery has failed or is contraindicated, and where some surgeons do not operate laparoscopically for technical reasons. In developing countries laparoscopic cholecystectomy is costly and is availa...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1046/j.1440-1622.2001.02046.x

    authors: Thomas S,Singh J,Bishnoi PK,Kumar A

    更新日期:2001-02-01 00:00:00

  • Review of knee arthroscopic practice and coding at a major metropolitan centre.

    abstract:BACKGROUND:Arthroscopic knee surgery has been a topic of significant controversy in recent orthopaedic literature. Multiple studies have used administrative (Victorian Admitted Episodes Dataset and Centre for Health Record Linkage) data to identify trends in practice. This study explored the usage and reporting of arth...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章,评审

    doi:10.1111/ans.13664

    authors: Lisik JP,Dowsey MM,Petterwood J,Choong PFM

    更新日期:2017-05-01 00:00:00

  • Preoperative factors prolonging the length of stay in elective colorectal surgery.

    abstract:BACKGROUND:In elective colorectal resections, the patient's preoperative social situation may play a significant role in delaying their discharge from hospital. The aim of this study was to identify which preoperative factors are associated with non-medical reasons for a delay in discharge and prolonged length of stay ...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2010.05587.x

    authors: Ngui NK,Hitos K,Ctercteko G

    更新日期:2011-09-01 00:00:00

  • Wound tension and 'closability' with keystone flaps, V-Y flaps and primary closure: a study in fresh-frozen cadavers.

    abstract:BACKGROUND:Previous publications have implied that the keystone flap provides mechanical benefits compared to primary closure. This has not been objectively demonstrated. METHODS:Elliptical defects were created in 'fresh-frozen' cadaveric specimens. Two approaches were used to investigate the potential mechanical bene...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.14163

    authors: Donovan LC,Douglas CD,Van Helden D

    更新日期:2018-05-01 00:00:00

  • Can pathological reports of rectal cancer provide national quality indicators?

    abstract:BACKGROUND:Rectal cancer care has become increasingly complex and requires accurate information. The pathology report is a vital tool for accessing information to gauge a patient's prognosis and to guide treatment decisions. The aim of this study was to assess the quality of histopathological reporting and surgery for ...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.14440

    authors: Keane C,Lin AY,Kramer N,Bissett I

    更新日期:2018-09-01 00:00:00

  • Surgical services: shaping future directions.

    abstract:BACKGROUND:Advances in surgical techniques and anaesthetic practise have facilitated a significant change in the way surgery is currently delivered. In particular, short stay surgery including ambulatory surgery has become the norm for the majority of surgical conditions. However, the planning of surgical services has ...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2011.05955.x

    authors: MacLellan DG,Smyth T,Cregan PC,Lizzio J,Watt H

    更新日期:2012-01-01 00:00:00

  • Functional response to total hip arthroplasty in patients with hip dysplasia.

    abstract:BACKGROUND:While recent studies have shown patients with developmental dysplasia of the hip (DDH) undergoing total hip arthroplasty (THA) to achieve comparable post-operative outcomes to patients with primary osteoarthritis (OA), it is unclear whether DDH patients display better or worse preoperative function than the ...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2012.06198.x

    authors: Boyle MJ,Singleton N,Frampton CM,Muir D

    更新日期:2013-07-01 00:00:00

  • Attitudes to evidence-based practice in urology: results of a survey.

    abstract:BACKGROUND:The advantages of promoting evidence-based care through implementation of clinical guidelines are well established. Clinical practice guidelines have been developed for lower urinary tract symptoms (LUTS) and prostate cancer screening. Aspects of the delivery of care by urologists or specialist registrars re...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1046/j.1440-1622.2001.02111.x

    authors: Stapleton AM,Cuncins-Hearn A,Pinnock C

    更新日期:2001-05-01 00:00:00

  • Investigations and time trends in loop ileostomy reversals following anterior resections: a single Australian institution seven-years' experience.

    abstract:BACKGROUND:Currently no consensus exists regarding what pre-reversal investigations are required to assess integrity of the rectal anastomosis. The objective of this study was to compare pre-reversal assessments of anastomotic integrity and to evaluate trends that might have influenced timings for reversal. METHODS:Fr...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.16483

    authors: Taylor D,Besson A,Faragher IG,Chan STF,Yeung JM

    更新日期:2020-12-09 00:00:00

  • Haemorrhagic complications of pancreaticoduodenectomy.

    abstract:BACKGROUND:Haemorrhagic complication occurs in 5-16% of patients following pancreaticoduodenectomy (PD). We report an analysis of patients with post-PD bleed, to identify predictors of bleed, predictors of survival following bleed and the management of post-PD bleed. METHODS:Two hundred and eighteen patients with peri...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-1433.2004.03212.x

    authors: Balachandran P,Sikora SS,Raghavendra Rao RV,Kumar A,Saxena R,Kapoor VK

    更新日期:2004-11-01 00:00:00

  • Does an Acute Surgical Model increase the rate of negative appendicectomy or perforated appendicitis?

    abstract:INTRODUCTION:The clinical outcomes from suspected appendicitis depend on balancing the rate of negative appendicectomy (NA) with perforated appendicitis (PA). An Acute Surgical Model (ASM) was introduced at Geelong Hospital (GH) in 2011 involving a dedicated emergency general surgery theatre list every business day giv...

    journal_title:ANZ journal of surgery

    pub_type: 临床试验,杂志文章

    doi:10.1111/ans.12211

    authors: Brockman SF,Scott S,Guest GD,Stupart DA,Ryan S,Watters DA

    更新日期:2013-10-01 00:00:00

  • Two-year serum metal ion levels in minimally invasive total conservative hip resurfacing: preliminary results of a prospective study.

    abstract:BACKGROUND:Metal-on-metal (MoM) hip resurfacings have been associated with the potential development of metallic debris and its associated pathology. Serum cobalt and chromium levels are a reliable surrogate marker of wear rates in MoM bearings. The aim of the study was to examine the trend in serum metal ion levels in...

    journal_title:ANZ journal of surgery

    pub_type: 临床试验,杂志文章

    doi:10.1111/ans.12868

    authors: Tai SM,Millard N,Munir S,Jenabzadeh AR,Walter LR,Walter WL

    更新日期:2015-03-01 00:00:00

  • Anastomotic leak in colorectal surgery: a single surgeon's experience.

    abstract:BACKGROUND:Anastomotic leakage following colorectal resection and anastomosis has been proposed as a colorectal surgical indicator. Leak rates after elective surgery vary and tend to be higher as anastomoses become lower. The present study audits leak rates and outcomes of patients undergoing colorectal surgery, under ...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1046/j.1440-1622.2001.02189.x

    authors: Isbister WH

    更新日期:2001-09-01 00:00:00

  • Revising the surgical registrar on-call roster.

    abstract:BACKGROUND:The work hours of junior doctors have been in the spotlight since the mid-1980s. Rostering and the structure of surgical units aim to balance quality and continuity of patient care with reasonable working hours. METHODS:Actual hours worked during two 12-week surgical registrar rosters were compared. Complia...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-2197.2010.05374.x

    authors: Wysocki AP,McGowan B

    更新日期:2010-07-01 00:00:00

  • Retrospective survival analysis of stage II-III rectal cancer: tumour regression grade, grading and lymphovascular invasion are the only predictors.

    abstract:BACKGROUND:Tumour regression grade is gaining interest as a prognostic factor of patients undergoing neoadjuvant chemoradiotherapy and surgery for locally advanced rectal cancer. METHODS:A series of 68 consecutive patients with locally advanced rectal cancer treated by neoadjuvant chemoradiotherapy and surgery between...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.16476

    authors: Morini A,Annicchiarico A,Romboli A,Ricco' M,Crafa P,Montali F,Dell'Abate P,Costi R

    更新日期:2020-12-14 00:00:00

  • Dorsal lumbotomy incision in paediatric pyeloplasty.

    abstract:BACKGROUND:The purpose of the present study was to comprehensively assess the results of surgical management of pelvi-ureteric junction (PUJ) obstruction using lumbotomy as the surgical approach. METHODS:Records of 36 consecutive patients with unilateral PUJ obstruction who underwent pyeloplasty in the last 5 years we...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/j.1445-1433.2004.03032.x

    authors: Bajpai M,Kumar A,Tripathi M,Bal CS

    更新日期:2004-06-01 00:00:00

  • Impact of post-haemorrhoidectomy pain relief checklists on pain outcomes: a randomized controlled trial.

    abstract:BACKGROUND:Haemorrhoidectomy is associated with significant post-operative pain which is primarily managed pharmacologically. Whether a non-pharmacological adjunct such as a checklist can improve pain outcomes after an open haemorrhoidectomy has yet to be studied. The purpose of this study was to determine if a patient...

    journal_title:ANZ journal of surgery

    pub_type: 杂志文章

    doi:10.1111/ans.15732

    authors: Huang J,Rickard MJFX,Keshava A,Suen MKL

    更新日期:2020-04-01 00:00:00