Abstract:
BACKGROUND:Tumour regression grade is gaining interest as a prognostic factor of patients undergoing neoadjuvant chemoradiotherapy and surgery for locally advanced rectal cancer. METHODS:A series of 68 consecutive patients with locally advanced rectal cancer treated by neoadjuvant chemoradiotherapy and surgery between 2010 and 2016 was retrospectively studied. The impact on disease-free survival (DFS) and overall survival (OS) of several criteria was analysed. Univariate analysis was performed through Kaplan-Meier statistics. Multivariate analysis was performed through Cox regression model. Using criteria found to be related to long-term outcomes, a predictive model of patient's OS was calculated. RESULTS:Poor tumour regression grade - TRG3 (P = 0.010), poor grading - G3 (P = 0.001) and lymphovascular invasion (LVI; P = 0.030) were associated with short OS at univariate analysis. OS was associated with TRG3 and G3 at multivariate analysis (P = 0.016 and P = 0.027, respectively). DFS was associated with LVI (P = 0.001), G3 tumours (P = 0.046) and TRG3 (P = 0.045) at univariate analysis. At multivariate analysis, only LVI was associated with DFS (P = 0.041). A score, pondering the impact of three parameters (2 points for TRG3, 2 for G3 and 1 for LVI), was created and resulted to predict patient OS (P = 0.008), ranging from 94.5 months (score = 0-1) to 32 months (score = 3-5). CONCLUSION:TRG3 and G3 were associated with poor OS, and LVI was the most significant predictor of DFS. An easy-to-use score may allow for a more accurate prediction of OS.
journal_name
ANZ J Surgjournal_title
ANZ journal of surgeryauthors
Morini A,Annicchiarico A,Romboli A,Ricco' M,Crafa P,Montali F,Dell'Abate P,Costi Rdoi
10.1111/ans.16476subject
Has Abstractpub_date
2020-12-14 00:00:00eissn
1445-1433issn
1445-2197pub_type
杂志文章abstract:BACKGROUND:Anticoagulation treatment in the community is common. This investigation was undertaken to determine the frequency of patient surgical admission with conditions associated with over-anticoagulation in the community and the surgical resource required to effectively and safely manage these patients acutely. M...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.13851
更新日期:2018-04-01 00:00:00
abstract:BACKGROUND:Human facial allotransplantation (FA) is a testament to the impressive progress, which was and is still happening in the field of transplantation medicine and reconstructive surgery. Like every pioneering treatment option, FA faces both the clinicians' and public opinion with a huge amount of medical and psy...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/j.1445-2197.2009.05140.x
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:There is increasing evidence that uncomplicated acute diverticulitis (UAD) can be safely and effectively managed as an outpatient. The aim of the current study was to evaluate if an early computed tomography (CT) scan in the emergency department (ED) can reduce the number of hospital admissions when UAD is d...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.15285
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:The volume of orthopaedic literature is increasing exponentially, becoming more widely scattered among journals. The rate of increase in orthopaedics is greater than other specialties. We aimed to identify the number of different journals an orthopaedic surgeon would need to read to stay up-to-date with curr...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12902
更新日期:2015-06-01 00:00:00
abstract::This article was presented at the conjoint CSSA and RACS (colorectal section) spring meeting Queensland, Australia, September 2004. The adenoma-carcinoma sequence describes a succession of events from polypoid adenoma to colorectal cancer. However, this model only accounts for up to two-thirds of colorectal cancers. T...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/j.1445-2197.2006.03847.x
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Nipple adenoma is a rare and benign type of breast tumour. Because of the lack of proper understanding, it is easily overlooked and misdiagnosed by doctors. The aim of the study is to improve clinicians' awareness of the disease. METHODS:Evaluation of the complaints such as blood discharge or nodules on the...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12744
更新日期:2015-06-01 00:00:00
abstract:BACKGROUND:Rectal cancer care has become increasingly complex and requires accurate information. The pathology report is a vital tool for accessing information to gauge a patient's prognosis and to guide treatment decisions. The aim of this study was to assess the quality of histopathological reporting and surgery for ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.14440
更新日期:2018-09-01 00:00:00
abstract:PURPOSE:The present study was undertaken to assess the degree of myocardial injury, using troponin T (TnT), in off-pump coronary artery surgery (OPCAB) and in a comparable patient group undergoing conventional coronary artery graft surgery (CABG). METHODS:Twenty-seven OPCAB and 27 CABG patients were investigated. Bloo...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1445-2197.2002.02317.x
更新日期:2002-02-01 00:00:00
abstract:BACKGROUND:Debridement and drainage have always been mainstream treatment for infected pancreatic necrosis (IPN), and the application of minimally invasive necrosectomy is becoming increasingly widespread. However, few studies have compared video-assisted retroperitoneal debridement (VARD) and small incision pancreatic...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.16181
更新日期:2020-08-11 00:00:00
abstract::Thirty-eight patients with mammary gland tuberculosis were evaluated over a 5-year period presenting to the surgical unit of our institution. Unilateral involvement of the breast in a woman presenting at an average age of 29 years was the commonest observation. A lump in the breast with or without discharging sinuses ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03692.x
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to investigate the effect of tissue engineering bone composed of bone marrow-derived osteoblasts and demineralized bone in repairing mandible defect. METHODS:Bone marrow-derived osteoblasts of 20 rabbits were cultured and seeded into scaffold of allogeneic demineralized bone...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2005.03586.x
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVE:This study reviews the functional outcome and satisfaction of patients after subtotal or total colectomy (STTC). METHODS:A retrospective review of patients who underwent STTC between June 1999 and September 2003 was performed. A standardized questionnaire was formulated and phone interviews were conducted wi...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2005.03552.x
更新日期:2005-10-01 00:00:00
abstract:BACKGROUND:The role of (18) F-fluorodeoxyglucose positron emission tomography/computed tomography ((18) F-FDG PET/CT) in evaluating pulmonary artery lesions has not yet been established. The purpose of this study is to evaluate the usefulness of (18) F-FDG PET/CT imaging in differentiating malignant from benign pulmona...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2012.06205.x
更新日期:2013-05-01 00:00:00
abstract::Chance meetings in the USA and in France lead to the realization of the potential for cholecystectomy to be performed laparoscopically. Outlined are the steps taken to learn the technique and perform the first such operation in Australia (with unusual circumstances), immediately followed by the introduction of audit a...
journal_title:ANZ journal of surgery
pub_type: 历史文章,杂志文章
doi:10.1111/j.1445-2197.2011.05898.x
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:The aim of this study was to identify factors associated with rupture in elderly patients with acute appendicitis. METHODS:The medical records of 601 consecutive patients >60 years of age with acute appendicitis between 1995 and 2005 were retrospectively reviewed. Historical, clinical and laboratory factors...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2007.04182.x
更新日期:2007-08-01 00:00:00
abstract::Abraham Colles had the good fortune to describe the most common fracture about the wrist but, because its description was published in a provincial journal, it received little attention and was almost never referred to in his lifetime. The same can be said of Claude Pouteau who described the same fracture in another l...
journal_title:ANZ journal of surgery
pub_type: 历史文章,杂志文章
doi:10.1111/j.1445-2197.2005.03414.x
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND:To evaluate the initial results of laparoscopic radical prostatectomy at this institution. METHODS:Between January 2000 and September 2003, 30 patients underwent laparoscopic radical prostatectomy. Peri- and postoperative data were accumulated prospectively and maintained in a database. All patients have a ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-1433.2004.03269.x
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:This study aimed to (i) investigate the factors that influence donor and recipient decision making in adult-to-adult living donor liver transplantation (AALDLT); (ii) quantify the level of risk that would be acceptable to potential donors; and (iii) determine from whom an individual would be willing to recei...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.12839
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:The ability to predict the behaviour of breast cancer from its dimensions allows the clinician to inform a woman about the absolute benefits of adjuvant therapies or further surgery to control her disease. Tumour size and grade are independent predictors of nodal disease. This study aims to generate a tool, ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2006.03918.x
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:Traumatic brain injury is a major cause of mortality and morbidity, particularly among young men. The efficacy and safety of most of the interventions used in the management of patients with traumatic brain injury remain unproven. Examples include the 'cerebral perfusion pressure-targeted' and 'volume-target...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/j.1445-2197.2006.03674.x
更新日期:2006-03-01 00:00:00
abstract:BACKGROUND:We describe a technique of U-shaped bulboprostatic anastomosis for urethral injury after pelvic trauma. METHODS:Sixty-eight male patients were included in our study. Suprapubic cystostomy was carried out initially, followed by U-shaped prostatobulbar anastomosis after 6-12 weeks. Follow ups were carried out...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2008.04584.x
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND:For proven gastro-oesophageal reflux disease, partial fundoplication is considered as effective as Nissen, but with fewer side effects. The aim of this meta-analysis was to compare the effect of laparoscopic partial fundoplication (LPF) with laparoscopic Nissen fundoplication (LNF). METHODS:Extensive medica...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,meta分析
doi:10.1111/j.1445-2197.2010.05637.x
更新日期:2012-01-01 00:00:00
abstract::Chronic constipation is a common condition in both adults and children. Children with chronic constipation frequently have symptoms that continue into adulthood. In the second part of the review we describe advances in the identification of abnormalities in the control of motility. The role of neurotransmitters in bot...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/j.1445-1433.2004.03202.x
更新日期:2004-10-01 00:00:00
abstract:BACKGROUND:The work hours of junior doctors have been in the spotlight since the mid-1980s. Rostering and the structure of surgical units aim to balance quality and continuity of patient care with reasonable working hours. METHODS:Actual hours worked during two 12-week surgical registrar rosters were compared. Complia...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2010.05374.x
更新日期:2010-07-01 00:00:00
abstract:AIM:To establish a proinflammatory cytokine profile of the cerebrospinal fluid (CSF) following trauma. BACKGROUND:Trauma is associated with a postinjury syndrome consisting of loss of weight and nitrogen, pyrexia, anorexia and fatigue. It has been proposed that cytokines are pathophysiologically involved in this syndr...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2005.03530.x
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND:The rates of breast reconstruction in Australian patients of culturally and linguistically diverse (CALD) backgrounds are currently unknown. This retrospective study determined the rate of breast reconstruction in women who had mastectomy as treatment for breast cancer at public hospitals in South Western Sy...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/ans.16298
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Surgical therapy for the thoracic aorta carries a high morbidity and mortality. Endovascular therapy for aneurysms and its adaptation to the thoracic aorta over the past 10 years is an exciting advance. This is a retrospective review of endovascular grafting of the thoracic aorta during the past decade at Ro...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2007.04293.x
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:Colorectal cancers represent a heterogenous group of tumours. While left segmental colectomy is an accepted and oncologically safe practice for left-sided colonic cancer (CC), some authors suggest that limited segmental resection of right-sided cancer should be debated in order to preserve length of the rese...
journal_title:ANZ journal of surgery
pub_type: 杂志文章,评审
doi:10.1111/ans.14276
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Internal pancreatic fistulas are well recognized complications of chronic pancreatitis. METHODS:Six patients with internal pancreatic fistulas were treated over a period of 5 years from 1995 to 1999. Four patients presented with ascites, one patient presented with ascites and bilateral pleural effusion and ...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1046/j.1440-1622.2001.02077.x
更新日期:2001-04-01 00:00:00
abstract::Acquired tracheo-oesophageal fistula is a devastating condition, usually occurring as a late manifestation of oesophageal or other thoracic malignancies. In these cases palliation by placement of an oesophageal stent is the preferred option, but management of a large non-malignant fistula is more complex. In many pati...
journal_title:ANZ journal of surgery
pub_type: 杂志文章
doi:10.1111/j.1445-2197.2007.04036.x
更新日期:2007-04-01 00:00:00