A novel 3' untranslated region mutation in the SLC29A3 gene associated with pigmentary hypertrichosis and non-autoimmune insulin-dependent diabetes mellitus syndrome.

abstract：OBJECTIVE:To describe insulin pump use by youth since introduction of universal funding in Ontario, Canada and to explore the relationship between pump use and pediatric diabetes center characteristics and the relationship between discontinuation and center and patient characteristics. RESEARCH DESIGN AND METHODS:Obse...

journal_title：Pediatric diabetes

authors： Shulman R,Stukel TA,Miller FA,Newman A,Daneman D,Guttmann A

更新日期：2017-02-01 00:00:00

abstract：:Type 1 diabetes is often accompanied with acute hypoinsulinemia that may theoretically inhibit the conversion of essential fatty acids to their longer-chain metabolites. Previously, we found significant reduction in plasma arachidonic (C20:4n-6) and docosahexaenoic (C22:6n-3) acid values in a group of diabetic childre...

journal_title：Pediatric diabetes

authors： Szabó E,Marosvölgyi T,Kozári A,Erhardt E,Soltész G,Decsi T

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Autoantibodies (A) against Neuropeptide Y (NPY), was reported in 9% newly diagnosed type 1 diabetes (T1D) patients. A single nucleotide polymorphism (SNP) at rs16139 (T1128C) within the NPY-gene identified an amino acid substitution from leucine (L) to proline (P) (L7P) associated with both glucose tolerance...

journal_title：Pediatric diabetes

authors： Skärstrand H,Vaziri-Sani F,Delli AJ,Törn C,Elding Larsson H,Ivarsson S,Agardh D,Lernmark Å,Skåne study group.

更新日期：2015-12-01 00:00:00

abstract：:In connection with the article entitled "A randomized trial comparing the rate of hypoglycemia – assessed using continuous glucose monitoring – in 125 preschool children with type 1 diabetes treated with insulin glargine or NPH insulin (the PRESCHOOL study)" which appeared in [1], we wish to bring the following correc...

journal_title：Pediatric diabetes

authors：

更新日期：2015-09-01 00:00:00

abstract：:The SLC29A3 gene, encoding hENT3, a member of the equilibrative nucleoside transporter family, has recently been found mutated in Faisalabad histiocytosis, pigmented hypertrichotic dermatosis with insulin-dependent diabetes, familial sinus histiocytosis with massive lymphadenopathy (SHML), and H syndromes. We here rep...

journal_title：Pediatric diabetes

authors： Elbarbary NS,Tjora E,Molnes J,Lie BA,Habib MA,Salem MA,Njølstad PR

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:The Environmental Determinants of Diabetes in the Young (TEDDY) study seeks to identify environmental triggers of autoimmunity and type 1 diabetes mellitus (T1DM) in children at increased human-leukocyte-antigen conferred genetic risk for this disease. The objective of this study was to identify predictors of...

journal_title：Pediatric diabetes

authors： Johnson SB,Lee HS,Baxter J,Lernmark B,Roth R,Simell T,TEDDY Study Group.

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:Type 2 diabetes mellitus (T2DM) is increasingly common among children and adolescents. However, achievement of good metabolic control has been difficult in this population. The aim of this study was to survey pediatric endocrine and diabetes specialists regarding the issues they consider to be barriers to suc...

journal_title：Pediatric diabetes

authors： Pinhas-Hamiel O,Zeitler P

更新日期：2003-03-01 00:00:00

abstract：:The association of type 1 diabetes mellitus (T1DM) and acute chorea is rare. We report an 8-yr-old boy with T1DM who developed acute hemichorea-hemiballism of the right arm in whom magnetic resonance imaging (MRI) of the brain revealed hyperintense signal in putamen and considerable atrophy and focal area of gliosis i...

journal_title：Pediatric diabetes

authors： Alves C,Sampaio S,Barbosa V,Machado M

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between triglyceride to high-density lipoprotein cholesterol (TG/HDL-C) ratio and carotid intima-medial thickness (CIMT) in Chinese youth and adolescents with newly diagnosed type 2 diabetes mellitus (T2DM). METHODS:Ninety-eight subjects aged 10-24 yr with newly-diagnosed T2DM...

journal_title：Pediatric diabetes

authors： Li X,Deng YP,Yang M,Wu YW,Sun SX,Sun JZ

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The autoimmune destruction of beta cells, resulting in clinical type 1 diabetes, may start early in life and last for several months or years. During this period of time, we have an opportunity to try to prevent or delay further beta-cell destruction and clinical onset of type 1 diabetes. OBJECTIVES:Ongoing...

journal_title：Pediatric diabetes

authors： Elding Larsson H

更新日期：2016-07-01 00:00:00

abstract：:Inadequate treatment adherence impedes achievement of glycemic control targets in type 1 diabetes (T1D). Valid and reliable measurement of treatment adherence is a prerequisite to rigorous evaluation of pertinent interventions. The diabetes self-management profile (DSMP), a structured interview measure of T1D adherenc...

journal_title：Pediatric diabetes

authors： Wysocki T,Buckloh LM,Antal H,Lochrie A,Taylor A

更新日期：2012-08-01 00:00:00

abstract：:The Juvenile Diabetes Research Foundation International (JDRF) was founded in 1970 by parents of children with juvenile diabetes to find a cure for diabetes and its complications through the support of research. The foundation was an early supporter of stem cell research, recognizing the promise of stem cells to quick...

journal_title：Pediatric diabetes

authors： Nierras CR,Stallard J,Goldstein RA,Insel R

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Diabetes ketoacidosis (DKA) is a common presentation and complication of type 1 diabetes (T1D). While intravenous insulin is typically used to treat acute metabolic abnormalities, the transition from intravenous to subcutaneous treatment can present a challenge. We hypothesize that co-administration of glarg...

journal_title：Pediatric diabetes

authors： Harrison VS,Rustico S,Palladino AA,Ferrara C,Hawkes CP

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Faster-acting insulin aspart (faster aspart) is insulin aspart (IAsp) in a new formulation with additional excipients (L-arginine and niacinamide). In adults, faster aspart provides faster onset and greater early exposure and action vs IAsp. AIM:This randomized, double-blind, 2-period crossover trial invest...

journal_title：Pediatric diabetes

authors： Fath M,Danne T,Biester T,Erichsen L,Kordonouri O,Haahr H

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Managing type 1 diabetes can be challenging, especially for youth, so there is a need for effective interventions to help youth live with diabetes. OBJECTIVE:To determine the efficacy of a coping skills training (CST) program for Chinese youth with type 1 diabetes and to explore whether the efficacy of the ...

journal_title：Pediatric diabetes

authors： Guo J,Luo J,Yang J,Huang L,Wiley J,Liu F,Li X,Zhou Z,Whittemore R

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:There are substantial controversies about the clinical utility of adolescent metabolic syndrome (MetS). The current study examined the stability of adolescent MetS by assessing the agreement and discriminative abilities of four different definitions of adolescent MetS and the adult MetS definit...

journal_title：Pediatric diabetes

authors： Asghari G,Eftekharzadeh A,Hosseinpanah F,Ghareh S,Mirmiran P,Azizi F

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Real-time continuous glucose monitoring systems (RT-CGMS) are a recently introduced technology for type 1 diabetes and experience in children is limited. OBJECTIVE:To assess patient and caregiver's perception of benefits and disadvantages of RT-CGMS in children or young adults with type 1 diabetes mellitus ...

journal_title：Pediatric diabetes

authors： Cemeroglu AP,Stone R,Kleis L,Racine MS,Postellon DC,Wood MA

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to investigate the importance of trust in researchers and other reasons that participating parents, former participants, and non-participants had for participating, or not participating, in a longitudinal cohort study on prediction and development of diabetes in children. STUD...

journal_title：Pediatric diabetes

authors： Helgesson G,Hansson MG,Ludvigsson J,Swartling U

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Mild hypoglycemia is commonly observed in children treated for type 1 diabetes mellitus (T1DM). Hypoglycemia disturbs cognition and learning. OBJECTIVE:To describe how and to what extent hypoglycemia in young children with T1DM is detected in everyday life. To learn how parents and caregivers treat hypoglyc...

journal_title：Pediatric diabetes

authors： Sundberg F,Forsander G

更新日期：2014-02-01 00:00:00

abstract：:Type 1 diabetes mellitus (T1DM) is the archetypal example of a T cell-mediated autoimmune disease characterized by selective destruction of pancreatic β cells. The pathogenic equation for T1DM presents a complex interrelation of genetic and environmental factors, most of which have yet to be identified. On the basis o...

journal_title：Pediatric diabetes

authors： Michels A,Zhang L,Khadra A,Kushner JA,Redondo MJ,Pietropaolo M

更新日期：2015-11-01 00:00:00

abstract：:Slow wave sleep (SWS), or deep sleep, is thought to be the most restorative stage of sleep and may be of a particular interest in the pathophysiology of obesity. The aim of this study was to investigate differences in sleep architecture based on body mass index (BMI) among a pediatric population with type 1 diabetes m...

journal_title：Pediatric diabetes

authors： Elrokhsi SH,Bluez GP,Chin CN,Wheeler MD,Silva GE,Perfect MM

更新日期：2020-02-01 00:00:00

abstract：UNLABELLED:Previous studies have shown that vigorous aerobic training programs for obese children result in minimal weight changes, and concluded that they may not be beneficial. Weight change alone may not detect important beneficial changes in body composition associated with vigorous training in these children. Fift...

journal_title：Pediatric diabetes

authors： DeStefano RA,Caprio S,Fahey JT,Tamborlane WV,Goldberg B

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVE:Identify and evaluate current treatment recommendations in Europe for the care of children with diabetes in view of the European Union (EU) recommendations for Reference Centers. METHODS:A questionnaire was sent in 2008 to representatives of all EU countries and Norway, all known to be actively involved in p...

journal_title：Pediatric diabetes

authors： de Beaufort C,Vazeou A,Sumnik Z,Cinek O,Hanas R,Danne T,Aschemeier B,Forsander G,SWEET group.

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Type 1 diabetes (T1D) mellitus and obesity are recognized risk factors for cardiovascular disease (CVD). A common mechanism underlying an increased risk for endothelial dysfunction in these two metabolic diseases is oxidative stress. OBJECTIVE:To evaluate and compare the oxidant/antioxidant defense systems ...

journal_title：Pediatric diabetes

authors： Codoñer-Franch P,Pons-Morales S,Boix-García L,Valls-Bellés V

更新日期：2010-06-01 00:00:00

abstract：OBJECTIVE:Type 1 diabetes (T1D) develops in distinct stages, before and after disease onset. Whether the natural course translates into different immunologic patterns is still uncertain. This study aimed at identifying peripheral immune patterns at key time-points, in T1D children undergoing remission phase. METHODS:C...

journal_title：Pediatric diabetes

authors： Fitas AL,Martins C,Borrego LM,Lopes L,Jörns A,Lenzen S,Limbert C

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The global rise in incidence of type 1 diabetes (T1D) is too rapid to be attributed to susceptible genetic background, pinpointing a significant role for environmental factors. Unlike the theory that the need for genetic susceptibility has lessened over time, we hypothesized that the rise in T1D incidence is...

journal_title：Pediatric diabetes

authors： Zung A,Na'amnih W,Bluednikov Y,Mery N,Blumenfeld O,Israel IDDM Registry Study Group (IRRSG).

更新日期：2018-06-01 00:00:00

abstract：:Type 1 diabetes is the most common form of diabetes in most part of the world, although reliable data are still unavailable in several countries. Wide variations exist between the incidence rates of different populations, incidence is lowest in China and Venezuela (0.1 per 100,000 per year) and highest in Finland and ...

journal_title：Pediatric diabetes

authors： Soltesz G,Patterson CC,Dahlquist G,EURODIAB Study Group.

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Teens with type 1 diabetes (T1D) experience increased sleep disturbances, which have been linked to problems with adherence and glycemic control. As such, sleep represents a novel target to improve outcomes in teens. OBJECTIVE:To evaluate the feasibility, acceptability, and preliminary efficacy of a sleep-p...

journal_title：Pediatric diabetes

authors： Jaser SS,Hamburger ER,Bergner EM,Williams R,Slaughter JC,Simmons JH,Malow BA

更新日期：2020-05-01 00:00:00

abstract：:Glucokinase gene (GCK) mutations comprise approximately 10% of cases of maturity-onset diabetes of the young (MODY). Over 800 different mutations in GCK have been reported in the Human Gene Mutation Database, the vast majority of which result in MODY type 2. The missense mutation p.Leu122Val is listed in that database...

journal_title：Pediatric diabetes

authors： Hunter JD,Staton H,Constantacos C,Walsh ET,Crudo DF

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:The Environmental Determinants of Diabetes in the Young (TEDDY) study is designed to identify environmental exposures triggering islet autoimmunity and type 1 diabetes (T1D) in genetically high-risk children. We describe the first 100 participants diagnosed with T1D, hypothesizing that (i) they are diagnosed ...

journal_title：Pediatric diabetes

authors： Elding Larsson H,Vehik K,Gesualdo P,Akolkar B,Hagopian W,Krischer J,Lernmark Å,Rewers M,Simell O,She JX,Ziegler A,Haller MJ,TEDDY Study Group.

更新日期：2014-03-01 00:00:00