Abstract:
:Sleep-related disorders have been reported to have a higher prevalence in multiple sclerosis (MS) than in the general population. They are often undervalued for the presence of more severe physical problems and the occurrence at night, without a direct observation in common clinical practice, but if not recognized and treated they can negatively affect the quality of life causing daytime drowsiness and worsening fatigue. Sleep related disorders most commonly reported in MS are as follows: insomnia, sleep-related breathing disorders (SRBD), restless legs syndrome (RLS) and periodic limb movement disorders (PLMD). Secondary narcolepsy, REM sleep behavior disorder (RBD) and propriospinal myoclonus have been also described in some case reports or series. The purpose of this review is to correlate the more common sleep disturbances in MS patients to the involvement of specific brain regions, analyzing their relationship with MRI findings. While insomnia is usually secondary to other disabling symptoms such as nocturia or pain, SRBD, RLS, narcolepsy, RBD and propriospinal myoclonus in MS patients can be the consequence of an injury of specific central nervous system (CNS) areas. Lesions in the pontine tegmentum and the dorsal medulla have been associated with SRBD, spinal cord lesions or atrophy with RLS, bilateral lesions in the lateral hypothalamus with narcolepsy-like symptoms, lesions in the dorsal pontine tegmentum with RBD and intramedullary demyelinating plaques in spinal cord with propriospinal myoclonus. MS specialists and general neurologists should be aware of these comorbidities since neuroimaging, which is routinely performed in MS, could provide helpful clinical indications on patients with secondary sleep-related disorders and to categorize symptomatic patients who need to underdo more in-depth sleep studies.
journal_name
Sleep Medjournal_title
Sleep medicineauthors
Foschi M,Rizzo G,Liguori R,Avoni P,Mancinelli L,Lugaresi A,Ferini-Strambi Ldoi
10.1016/j.sleep.2019.01.010subject
Has Abstractpub_date
2019-04-01 00:00:00pages
90-97eissn
1389-9457issn
1878-5506pii
S1389-9457(18)30387-3journal_volume
56pub_type
杂志文章,评审相关文献
SLEEP MEDICINE文献大全abstract:OBJECTIVES:This study aimed to evaluate children's bedtime, wake-up time, total sleep duration (TSD), sleep latency, and daytime napping by age and gender. Its secondary aim was to compare sleep duration among demographic and lifestyle factors. METHODS:We performed a cross-sectional study of 3639 children in Daegu, Ko...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2010.03.011
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Patients with obstructive sleep apnea syndrome (OSAS) are known to have an increased risk for motor vehicle crashes. They suffer from sleep-related respiratory abnormality causing repetitive arousal leading to daytime sleepiness. In turn, it has been demonstrated that sleepiness can impair human psychomotor ...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2008.11.005
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:Sleep-disordered breathing (SDB) is often co-morbid with conductive hearing loss in early childhood due to a shared aetiology of adenotonsillar hypertrophy. Hearing loss is independently associated with impairment of executive function and behavioural difficulties. We hypothesised that these impairments in c...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2017.02.008
更新日期:2017-06-01 00:00:00
abstract::This report describes a patient with iron deficiency in bone marrow examination and iron-responsive restless legs syndrome (RLS), in whom serum ferritin levels were well above the conventional cutoff for considering iron deficiency. The predictive value of serum ferritin for iron deficiency in RLS depends on the cutof...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2004.10.008
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND:Noise in the vicinity of airports is a public health issue. Exposure to aircraft noise has been shown to have adverse effects on health and particularly on sleep. Many studies support the hypothesis that noise at night can affect subjective sleep quality. Fewer studies, however, have performed objective meas...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2018.10.013
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:The purpose of this study is to examine how the sleep duration changes during adolescence across the seventh, eighth, ninth, and 10th grade periods, and to determine whether there is a difference between the cohorts. METHOD:For these purposes, we used the latent growth curve modeling and the multi-group anal...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2019.10.025
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVES:Previous studies comparing objective sleep measures between patients with Parkinson's disease (PD) and control participants were limited by their small sample size. The purpose of this study was to compare objective sleep measures between large-scale cohorts of PD outpatients and community-based older adults...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2019.09.010
更新日期:2020-04-01 00:00:00
abstract:OBJECTIVES:The microbiota-gut-brain axis is an intricate communication network that is emerging as a key modulator of psychological and physiological wellbeing. Recent pioneering work in the field has suggested a possible link between gut microbiome composition with sleep, an evolutionarily conserved behavior demonstra...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2020.04.013
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence and severity of restless legs syndrome (RLS) in a town in China and to explore potential factors correlated with the severity of the disease. METHODS:Face-to-face home interviews were conducted among a random sample of 2101 residents in one town in China, all aged 16 years and above....
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2011.09.008
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:To examine whether snoring and sleepiness are linked in pregnancy and pre-eclampsia. PATIENTS AND METHODS:We recruited 167 healthy and 82 pre-eclamptic women in the third trimester of pregnancy and 160 non-pregnant women. Subjects and their partners completed a sleep questionnaire. Height, weigh...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2004.12.007
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:Sleep-disordered breathing is associated with hypertension and cardiovascular disease. Increased aortic stiffness is one possible linking mechanism. We evaluated the association between sleep-disordered breathing and aortic stiffness in a community-based sample. METHODS:Our community-based cross-sectional ob...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2015.11.009
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVE:Ramelteon, an MT(1)/MT(2) melatonin receptor agonist, was evaluated for its ability to reduce sleep-onset difficulties associated with eastward jet travel. METHODS:Healthy adults (n=110) with a history of jet lag sleep disturbances were flown eastward across five time zones from Hawaii to the east coast of t...
journal_title:Sleep medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.sleep.2010.03.010
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:Although some authors have recently investigated the co-occurrence of posttraumatic stress disorder (PTSD) and obstructive sleep apnea (OSA), the topic remains insufficiently studied. The aim of this meta-analysis was to detect the pooled prevalence of OSA in PTSD and its impact on adherence to continuous pos...
journal_title:Sleep medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.sleep.2017.04.020
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Obstructive sleep apnoea (OSA) has the potential to cause heart failure. We aimed to determine the effects of nasal continuous positive airway pressure (CPAP) therapy on left ventricular structure and myocardial performance index (MPI) in severe OSA patients. METHODS:Sixty-seven subjects without any cardiac...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2006.04.007
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:Obstructive sleep apnea (OSA) is an independent risk factor for cardiovascular disease because of its associated autonomic nervous and vascular regulatory dysfunctions. We tested the hypothesis that the multiscale entropy (MSE) approach to heart rate variability analysis may be used for evaluating OSA severit...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2015.11.021
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:As the relationships of sleep-wake schedule and mealtime with children's behaviors have not often been studied together, we investigated the relationships of these lifestyles variables with preschool children's well-being. METHODS:Using a network survey, we investigated several lifestyle variables of 1000 fa...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2019.03.023
更新日期:2019-09-01 00:00:00
abstract::Circadian clocks are intracellular molecular mechanisms designed to allow the cell, organ, and organism to prepare for an anticipated stimulus prior to its onset. In order for circadian clocks to maintain their selective advantage, they must be entrained to the environment. Light, sound, temperature, physical activity...
journal_title:Sleep medicine
pub_type: 杂志文章,评审
doi:10.1016/j.sleep.2006.12.010
更新日期:2007-09-01 00:00:00
abstract:OBJECTIVE:To provide normative values for sleep macroarchitecture of healthy children aged 1-18 years using the AASM sleep scoring criteria, assessing the effects of gender, age, and Tanner pubertal stage. METHODS:One-night polysomnography was performed at subjects' habitual bedtimes in 16 laboratories on 209 healthy ...
journal_title:Sleep medicine
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.sleep.2010.11.011
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVES:Nightmares are extremely unpleasant and vivid recurring dreams that are accompanied with awakening during sleep. However, earlier studies were mostly conducted with children and adults, with very few studies on nightmares in older adults. This population-based study aims to investigate the prevalence of nigh...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2020.11.039
更新日期:2020-12-04 00:00:00
abstract:OBJECTIVE:The purpose of this study was to examine the association between sleep and subjective quality of life in an elderly Japanese population. METHODS:Elderly people aged 70 years or more (n=1,769) were selected randomly from all areas of Japan. They were visited and interviewed in November 2003. Subjective well-b...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2007.02.007
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Obstructive sleep apnea (OSA) is associated with increased cardiovascular morbidity and mortality which may be mediated by increased arterial stiffness and endothelial dysfunction. Continuous positive airway pressure (CPAP) therapy improves excessive daytime somnolence (EDS), but its effect on vascular funct...
journal_title:Sleep medicine
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.sleep.2013.08.786
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Continuous positive airway pressure (CPAP) is an effective treatment for sleep apnea (SA), although the evidence for improving chronic heart failure (CHF) is inconclusive. Our aim was to evaluate the effect of CPAP treatment on the left ventricle ejection fraction (LVEF) among other cardiological...
journal_title:Sleep medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.sleep.2007.06.018
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVE:A social gradient in sleep has been demonstrated across the life span, but previous studies have been cross-sectional and used self-reported socioeconomic status (SES) indicators. Using registry-based data on family income trajectories, the current study examined the association between relative poverty in ch...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2017.06.005
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND AND PURPOSE:To evaluate the test-to-test variability of the suggested immobilization test (SIT) in patients with restless legs syndrome (RLS). PATIENTS AND METHODS:Twenty patients with primary RLS (12 men and eight women; age: 53.3+/-11.3 years) were selected for the study. We compared the results of two SI...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2006.02.007
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVES:The present study aimed to clarify the prevalence and risk factors of insomnia among public school teachers in Japan by examining the relationships between working hours, commuting time, and insomnia. Time spent on work activities among teachers with insomnia was also investigated. METHODS:This study was a ...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2019.09.017
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:The effects of obstructive sleep apnoea (OSA) on the markers of glucose metabolism and other hormones are of interest, particularly since there is growing evidence that OSA may be a risk factor for disorders such as insulin resistance. However, interpreting these studies depends on the target hormone not havi...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2011.01.020
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Insomnia marked by sleep maintenance difficulty is extremely prevalent. Yet, problems staying asleep have been relatively neglected as a research focus compared to problems falling asleep. Insomnia treatment studies typically have not required participants to have a problem specifically with sleep maintenanc...
journal_title:Sleep medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.sleep.2012.01.010
更新日期:2012-06-01 00:00:00
abstract::Sleep-related eating disorder (SRED) is characterized by nocturnal partial arousals associated with compulsive consumption of food and altered levels of consciousness. Reports of an increased incidence of SRED in relatives of affected individuals suggest a genetic predisposition. We report a woman with SRED whose frat...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/s1389-9457(02)00137-5
更新日期:2002-11-01 00:00:00
abstract:STUDY OBJECTIVES:Early life determinants of sleep problems are mostly unknown. The first 1000 days of life (ie, the time between conception and a child's second birthday) is a period where the foundations for optimum health, growth and neurodevelopment are established. The aim of this explorative study is to identify p...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2019.12.020
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:To investigate clinical and dopaminergic pre-synaptic brain imaging characteristics of subjects with idiopathic rapid eye movement (REM) behavior disorder (iRBD) and mild cognitive impairment (MCI), and to evaluate the combined predictive value of risk factors for short-term conversion to synucleinopathy. ME...
journal_title:Sleep medicine
pub_type: 杂志文章
doi:10.1016/j.sleep.2020.02.011
更新日期:2020-02-29 00:00:00