Current views on tumor mutational burden in patients with non-small cell lung cancer treated by immune checkpoint inhibitors.

abstract：:Since its inception, minimally invasive surgery has made a dramatic impact on all branches of surgery. Video-assisted thoracic surgery (VATS) lobectomy for early-stage non-small cell lung cancer (NSCLC) was first described in the early 1990s and has since become popular in a number of tertiary referral centers. Propon...

journal_title：Journal of thoracic disease

authors： Cao CQ,Stine ML,Yan TD

更新日期：2009-12-01 00:00:00

abstract：:Approximately 6% of women with breast cancer are diagnosed before the age of 40. Young age is an independent predictor of adverse outcome and most young breast cancer patients receive systemic treatment with chemotherapy, hormonal therapy or both. The loss or impairment of fertility is a potential side effect of antin...

journal_title：Journal of thoracic disease

authors： Lambertini M,Anserini P,Levaggi A,Poggio F,Del Mastro L

更新日期：2013-06-01 00:00:00

abstract：:In many areas of the world, concentrations of ambient air pollutants exceed levels associated with increased risk of acute and chronic health problems. While effective policies to reduce emissions at their sources are clearly preferable, some evidence supports the effectiveness of individual actions to reduce exposure...

journal_title：Journal of thoracic disease

authors： Laumbach R,Meng Q,Kipen H

更新日期：2015-01-01 00:00:00

abstract：Background:Interatrial block (IAB) has been previously shown to predict atrial fibrillation (AF) in cardiac populations. This study sought to evaluate the relationship between IAB and new-onset AF in a population of patients undergoing clinically indicated coronary angiography who received carotid ultrasonography. Met...

journal_title：Journal of thoracic disease

authors： Alexander B,Baranchuk A,Haseeb S,van Rooy H,Kuchtaruk A,Hopman W,Çinier G,Hetu MF,Li TY,Johri AM

更新日期：2018-07-01 00:00:00

abstract：Background:Radical resection is the cornerstone for patients with early stage of non-small cell lung cancer (NSCLC). However, fatal disease recurs in about 30-70% of resected cases. The circulating tumor cells (CTCs) is one of the main causes of recurrence of cancer. Circulating tumor DNA (ctDNA) is also a potential pr...

journal_title：Journal of thoracic disease

authors： Liang H,Huang J,Wang B,Liu Z,He J,Liang W

更新日期：2018-04-01 00:00:00

abstract：Background:The purpose of this study is to report the efficacy of the mono antiplatelet plus anticoagulation therapy for prevention of reocclusion in patients with atrial fibrillation (AF) undergoing endovascular treatment for lower extremity ischemia. Methods:From March 2014 to July 2016, 32 (21 males; range, 68-84 y...

journal_title：Journal of thoracic disease

authors： Yuan L,Chen C,Li Z,Zhu G,Bao J,Zhao Z,Lu Q,Jing Z

更新日期：2018-03-01 00:00:00

abstract：Background:Robotic lobectomy is widely used for lung cancer treatment. So far, few studies have been performed to systematically analyze the learning curve. Our purpose is to define the learning curve to provide a training guideline of this technique. Methods:A total of 208 consecutive patients with primary lung cance...

journal_title：Journal of thoracic disease

authors： Song G,Sun X,Miao S,Li S,Zhao Y,Xuan Y,Qiu T,Niu Z,Song J,Jiao W

更新日期：2019-06-01 00:00:00

abstract：Background:To describe a single-institutional experience with an innovative technique using CT-guided injection of autologous blood for localization of nonpleural-based pulmonary nodules prior to thoracoscopic excisional biopsy in pediatric patients. Methods:A retrospective review of all patients under the age of 18 w...

journal_title：Journal of thoracic disease

authors： Sheikh F,Brandt RJ,Tsapakos MJ,Baertschiger RM,Croitoru DP

更新日期：2020-08-01 00:00:00

abstract：:Cerebral oximetry based on near-infrared spectroscopy (NIRS) is increasingly used during the perioperative period of cardiovascular operations. It is a noninvasive technology that can monitor the regional oxygen saturation of the frontal cortex. Current literature indicates that it can stratify patients preoperatively...

journal_title：Journal of thoracic disease

authors： Vretzakis G,Georgopoulou S,Stamoulis K,Stamatiou G,Tsakiridis K,Zarogoulidis P,Katsikogianis N,Kougioumtzi I,Machairiotis N,Tsiouda T,Mpakas A,Beleveslis T,Koletas A,Siminelakis SN,Zarogoulidis K

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND:Metachronous malignancy is also found in the lung cancer population and may be identified before or after diagnosis of lung cancer. No prior studies have documented lung cancer patients with metachronous malignancy and its survival impact in this population. The aim of this study was to try to clarify the su...

journal_title：Journal of thoracic disease

authors： Wen CT,Fu JY,Wu CF,Hsieh MJ,Liu YH,Wu YC,Tsai YH,Wu CY

更新日期：2016-06-01 00:00:00

abstract：Background:The aim of this study was to retrospectively investigate the diagnostic accuracy of ultrasound-guided pleural cutting needle biopsy (US-guided PCNB) and the potential factors influencing diagnostic yield. Methods:From July 2014 to June 2016, a total of 147 percutaneous US-guided PCNBs in 144 patients were r...

journal_title：Journal of thoracic disease

authors： Zhang Y,Tang J,Zhou X,Zhou D,Wang J,Tang Q

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Concurrent chemoradiotherapy (CRT) with 5-fluorouracil (5-FU) and cisplatin (CDDP) are often associated with significant incidence of toxic effects in elderly patients with esophageal cancer. This phase I trial was designed to determine the maximum tolerated dose (MTD) and dose-limiting toxicity (DLT) of S-1...

journal_title：Journal of thoracic disease

authors： Ji Y,Qiu G,Sheng L,Sun X,Zheng Y,Chen M,Du X

更新日期：2016-03-01 00:00:00

abstract：Background:Consolidation durvalumab improved overall survival (OS) in locally advanced non-small cell lung cancer (LA-NSCLC) treated with chemoradiotherapy (CRT) in the PACIFIC trial; however, pneumonitis was increased with durvalumab. We sought to examine real-world outcomes with the PACIFIC paradigm, especially facto...

journal_title：Journal of thoracic disease

authors： Hassanzadeh C,Sita T,Savoor R,Samson PP,Bradley J,Gentile M,Roach M,Mohindra N,Waqar S,Kruser TJ,Robinson C

更新日期：2020-11-01 00:00:00

abstract：Background:Good compliance in chronic obstructive pulmonary disease (COPD) is of 'paramount importance' in reducing the occurrence of acute exacerbations, hospitalisation and mortality and in improving quality of life. However, a number of studies have confirmed that long-term compliance is low and often associated wit...

journal_title：Journal of thoracic disease

authors： O'Hagan P,Dederichs J,Viswanad B,Gasser M,Walda S

更新日期：2018-10-01 00:00:00

abstract：:Idiopathic pulmonary fibrosis (IPF) is the most common cause of interstitial lung disease (ILD) and carries a worse prognosis than many cancers. Until recently, there were no active treatment options available for patients with IPF, meaning palliation or lung transplantation in selected patients were the only options....

journal_title：Journal of thoracic disease

authors： Shaw J,Marshall T,Morris H,Hayton C,Chaudhuri N

更新日期：2017-11-01 00:00:00

abstract：:Arnold's nerve ear-cough reflex is recognised to occur uncommonly in patients with chronic cough. In these patients, mechanical stimulation of the external auditory meatus can activate the auricular branch of the vagus nerve (Arnold's nerve) and evoke reflex cough. This is an example of hypersensitivity of vagal affer...

journal_title：Journal of thoracic disease

authors： Ryan NM,Gibson PG,Birring SS

更新日期：2014-10-01 00:00:00

abstract：:During recent years, continuous technological innovation has provoked an increase of extracorporeal life support (ECLS) use for perioperative cardiopulmonary support in lung transplantation. Initial results were disappointing, due to ECLS-specific complications and high surgical risk of the supported patients. However...

journal_title：Journal of thoracic disease

authors： Ius F,Tudorache I,Warnecke G

更新日期：2018-08-01 00:00:00

abstract：Background:The aim of this study is to evaluate the five-year outcomes after thoracic endovascular aortic repair (TEVAR) of symptomatic Stanford type B penetrating aortic ulcer (PAU) associated with intramural hematoma (IMH) in Chinese patients. Methods:From January 2009 to April 2013, 118 patients with typical severe...

journal_title：Journal of thoracic disease

authors： Liu J,Liu Y,Yang W,Gu J,Xue S

更新日期：2019-01-01 00:00:00

abstract：:Central venous catheters (CVCs) have an important role in the management of critically ill patients. In contrast to the immediate complications after CVC insertion, the late complications were difficult to be noticed without high suspicion despite their life-threatening outcome. We report a rare but fatal delayed vasc...

journal_title：Journal of thoracic disease

authors： Kim YJ,Kim WY

更新日期：2017-09-01 00:00:00

abstract：:Surgical procedures of pleural cavity are crucial to complete the diagnoses or planning treatment of pleural effusions with an unknown aetiology. Traditionally, the transthoracic approach has been the most used procedure to study the pleural cavity. The subxiphoid video-thoracoscopy is becoming an alternative to the t...

journal_title：Journal of thoracic disease

authors： Martínez-Téllez E,Trujillo-Reyes JC,Guarino M,Rami-Porta R,Belda-Sanchis J

更新日期：2018-08-01 00:00:00

abstract：:As "Immunotherapy age" is coming, immune checkpoint inhibitors (CPI) therapies have shown favorable clinical benefits and low toxicity profiles in patients with advanced non-small cell lung cancer (NSCLC). While it is a pity that there is a little clear clinical trials evidence about immunotherapy among Asian populati...

journal_title：Journal of thoracic disease

authors： Peng L,Wu YL

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Rapid on-site evaluation (ROSE) of cytologic specimens is a useful ancillary technique in needle aspiration procedures of pulmonary/mediastinal lesions, but few reports had been carried out to confirm the utility in the diagnosis of peripheral pulmonary lesions (PPLs) by radial probe endobronchial ultrasound...

journal_title：Journal of thoracic disease

authors： Chen CH,Cheng WC,Wu BR,Chen CY,Chen WC,Hsia TC,Liao WC,Tu CY,Shih CM,Hsu WH,Wang KP

更新日期：2015-12-01 00:00:00

abstract：:The scientific world is enriched daily with new knowledge, due to new technologies and continuous discoveries. The mathematical functions explain the statistical concepts particularly those of mean, median and mode along with those of frequency and frequency distribution associated to histograms and graphical represen...

journal_title：Journal of thoracic disease

authors： Divisi D,Di Leonardo G,Zaccagna G,Crisci R

更新日期：2017-06-01 00:00:00

abstract：:We report a case of video-assisted thoracoscopic surgery (VATS) tracheal resection and carinal reconstruction in a patient with tracheal tumor. The patient presented with adenoid cystic carcinoma (ACC) of the distal trachea, extending along the right main bronchus with carinal invasion. The reconstruction procedure wa...

journal_title：Journal of thoracic disease

authors： He J,Wang W,Li J,Yin W,Xu X,Peng G,Chen Y,He P

更新日期：2016-01-01 00:00:00

abstract：Background:Although robot-assisted minimally-invasive esophagectomy (RAMIE) surgeries are expanding clinically, few studies have reported patients with locally-advanced esophageal cancer who underwent neoadjuvant chemoradiation therapy (nCRT). Methods:From 2013 to 2017, 219 patients with esophageal squamous cell carci...

journal_title：Journal of thoracic disease

authors： Yun JK,Lee IS,Gong CS,Kim BS,Kim HR,Kim DK,Park SI,Kim YH

更新日期：2019-07-01 00:00:00

abstract：:Prosthetic valve endocarditis (PVE) after transcatheter aortic valve implantation (TAVI) or surgical aortic valve replacement (SAVR) is a potential life threatening complication. Better understanding of the incidence, predictors, clinical presentation, diagnostic measures, complications and management of PVE may help ...

journal_title：Journal of thoracic disease

authors： Ahmad K,Klaaborg KE,Hjortdal V,Nørgaard BL,Terkelsen CJ,Jensen K,Christiansen EH,Terp KA,Andersen G,Hvitfeldt S,Andersen HR

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Plaques with a large necrotic core or lipid pool and thin-cap fibroatheroma manifest as attenuated plaques on intravascular ultrasound (IVUS). Their impact on TIMI grade flow and clinical outcomes remains undefined. We performed a systematic review and meta-analysis to summarize the association between atten...

journal_title：Journal of thoracic disease

authors： Jia R,Nie X,Li H,Zhu H,Pu L,Li X,Han J,Yang D,Meng S,Jin Z

更新日期：2016-03-01 00:00:00

abstract：Background:Vitamin C has shown several beneficial effects on sepsis in preclinical studies. However, clinical data supporting these reports are scarce. This study aimed to evaluate whether adjunctive intravenous vitamin C therapy could reduce hospital mortality in patients with severe sepsis or septic shock requiring m...

journal_title：Journal of thoracic disease

authors： Ahn JH,Oh DK,Huh JW,Lim CM,Koh Y,Hong SB

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Influenza surveillance is carried out in Guangdong province, southern China. A better understanding of influenza seasonality and predominant Subtypes of influenza virus in Guangdong can help to improve evidence-based prevention and control strategies for influenza in the future. MATERIALS AND METHODS:THERE ...

journal_title：Journal of thoracic disease

authors： Lin J,Kang M,Zhong H,Zhang X,Yang F,Ni H,Huang P,Hong T,Ke C,He J

更新日期：2013-08-01 00:00:00

abstract：Background:Right anterior mini-thoracotomy (MIAVR) is a promising technique for aortic valve replacement. We aimed at comparing its outcomes with those obtained in a propensity-matched group of patients undergoing sternotomy at our two high-volume centers. Methods:Main clinical and operative data of patients undergoin...

journal_title：Journal of thoracic disease

authors： Del Giglio M,Mikus E,Nerla R,Micari A,Calvi S,Tripodi A,Campo G,Maietti E,Castriota F,Cremonesi A

更新日期：2018-03-01 00:00:00