Arnold's nerve cough reflex: evidence for chronic cough as a sensory vagal neuropathy.

Abstract:

:Arnold's nerve ear-cough reflex is recognised to occur uncommonly in patients with chronic cough. In these patients, mechanical stimulation of the external auditory meatus can activate the auricular branch of the vagus nerve (Arnold's nerve) and evoke reflex cough. This is an example of hypersensitivity of vagal afferent nerves, and there is now an increasing recognition that many cases of refractory or idiopathic cough may be due to a sensory neuropathy of the vagus nerve. We present two cases where the cause of refractory chronic cough was due to sensory neuropathy associated with ear-cough reflex hypersensitivity. In both cases, the cough as well as the Arnold's nerve reflex hypersensitivity were successfully treated with gabapentin, a treatment that has previously been shown to be effective in the treatment of cough due to sensory laryngeal neuropathy (SLN).

journal_name

J Thorac Dis

authors

Ryan NM,Gibson PG,Birring SS

doi

10.3978/j.issn.2072-1439.2014.04.22

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

S748-52

issue

Suppl 7

eissn

2072-1439

issn

2077-6624

pii

jtd-06-S7-S748

journal_volume

6

pub_type

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