Noeud Vital and the Respiratory Centers.

Abstract:

:We now recognize that the main breathing generator resides principally in the medulla oblongata. Vivisectionists-specifically, Julien Legallois-discovered "the respiratory center." Cutting through the brainstem stops respiration but not if the medulla remains intact and the brain is sliced in successive portions. Pierre Flourens localized surgical ablation experiments further identified a 1-mm area in the medulla, which he called vital knot or node (noeud vital). Detailed characterization had to wait until the 1920s, when Lumsden carried out more specific transection experiments to improve morphological differentiation of the respiratory center into inspiratory and expiratory divisions.

journal_name

Neurocrit Care

journal_title

Neurocritical care

authors

Wijdicks EFM

doi

10.1007/s12028-019-00686-8

subject

Has Abstract

pub_date

2019-08-01 00:00:00

pages

211-215

issue

1

eissn

1541-6933

issn

1556-0961

pii

10.1007/s12028-019-00686-8

journal_volume

31

pub_type

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