Abstract:
:We now recognize that the main breathing generator resides principally in the medulla oblongata. Vivisectionists-specifically, Julien Legallois-discovered "the respiratory center." Cutting through the brainstem stops respiration but not if the medulla remains intact and the brain is sliced in successive portions. Pierre Flourens localized surgical ablation experiments further identified a 1-mm area in the medulla, which he called vital knot or node (noeud vital). Detailed characterization had to wait until the 1920s, when Lumsden carried out more specific transection experiments to improve morphological differentiation of the respiratory center into inspiratory and expiratory divisions.
journal_name
Neurocrit Carejournal_title
Neurocritical careauthors
Wijdicks EFMdoi
10.1007/s12028-019-00686-8subject
Has Abstractpub_date
2019-08-01 00:00:00pages
211-215issue
1eissn
1541-6933issn
1556-0961pii
10.1007/s12028-019-00686-8journal_volume
31pub_type
历史文章,杂志文章abstract:BACKGROUND:Cerebral edema, which is associated with increased intracranial fluid, is often a complication of many acute neurological conditions. There is currently no accepted method for real-time monitoring of intracranial fluid volume at the bedside. We evaluated a novel noninvasive technique called "Volumetric Integ...
journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-017-0409-4
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Nosocomial pneumonia (NP) is a frequent complication among spontaneous intracerebral hemorrhage (sICH) patients. This study was aimed at identifying in-hospital risk factors that predispose sICH patients to NP. METHODS:We identified 591 consecutive sICH subjects admitted to six tertiary care hospitals betwe...
journal_title:Neurocritical care
pub_type: 杂志文章,多中心研究
doi:10.1007/s12028-014-0065-x
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Hyponatremia may complicate brain injury and exacerbate cerebral edema and intracranial pressure (ICP). Vasopressin-receptor antagonists (such as conivaptan) are promising novel agents to treat hyponatremia that act by inducing aquaresis. It is unclear whether raising serum sodium in this way could also conf...
journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-010-9366-x
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Oral anticoagulants have been associated with greater hematoma expansion in patients with intracerebral hemorrhage (ICH). The purpose of this study was to determine whether the reported use of antiplatelet agents also results in greater hematoma expansion. METHODS:Retrospective review of patients with spont...
journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-009-9290-0
更新日期:2010-02-01 00:00:00
abstract:INTRODUCTION:A case of cefepime-induced nonconvulsive status epilepticus in a 15-year-old child with end stage renal disease on hemodialysis is reported. Clinical symptoms and EEG dramatically improved 48 h after discontinuation of cefepime. METHODS:Twenty-five cases of nonconvulsive status epilepticus associated with...
journal_title:Neurocritical care
pub_type: 杂志文章,评审
doi:10.1007/s12028-008-9166-8
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Early recognition and treatment of autoimmune encephalitis (AE) has become an essential issue in clinical practice. However, little is known about patients with deteriorating conditions and the need for intensive care treatment. Here, we aimed to characterize underlying aetiologies, clinical symptoms, reason...
journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-016-0370-7
更新日期:2017-08-01 00:00:00
abstract::Neuromuscular disorders increasingly are recognized as a complication in patients in the intensive care unit (ICU) and represent a common cause of prolonged ventilator dependency. The distinct syndromes of critical illness myopathy, prolonged neuromuscular blockade, and critical illness polyneuropathy (CIP) may arise ...
journal_title:Neurocritical care
pub_type: 杂志文章,评审
doi:10.1385/NCC:3:3:195
更新日期:2005-01-01 00:00:00
abstract::In this article, we review technologies available for direct monitoring of cerebral oxygenation and metabolic status, including jugular venous oxygen saturation, brain tissue oxygen tension, transcranial cerebral oximetry with near-infrared spectroscopy, Positron emission tomography oxidative metabolism, single-photon...
journal_title:Neurocritical care
pub_type: 杂志文章,评审
doi:10.1385/ncc:4:1:083
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:This prospective consecutive double-blinded randomized study investigated the effect of prostacyclin on pressure reactivity (PR) in severe traumatic brain injured patients. Other aims were to describe PR over time and its relation to outcome. METHODS:Blunt head trauma patients, Glasgow coma scale ≤8, age 15...
journal_title:Neurocritical care
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12028-014-0030-8
更新日期:2015-02-01 00:00:00
abstract:BACKGROUND:Acute hydrocephalus is a common complication of aneurysmal subarachnoid hemorrhage (aSAH); however, attempts to predict shunt-dependent chronic hydrocephalus using clinical parameters have been equivocal. METHODS:Cohort study of aSAH is treated with external ventricular drainage (EVD) placement at our insti...
journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-019-00886-2
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Animal studies suggested that cerebral mitochondrial cardiolipin phospholipids were released after severe traumatic brain injury (TBI), contributing to the pathogenesis of thromboembolism. OBJECTIVES:To determine the incidence of anti-cardiolipin antibodies after severe TBI and whether this was related to t...
journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-020-01026-x
更新日期:2020-06-18 00:00:00
abstract:BACKGROUND:Fever in neurocritical care patients is common and has a negative impact on neurological outcome. The purpose of this prospective observational study was (1) to evaluate the practicability of cooling with newly developed neck pads in the daily setting of neurointensive care unit (NICU) patients and (2) to ev...
journal_title:Neurocritical care
pub_type: 临床试验,杂志文章
doi:10.1007/s12028-010-9451-1
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:Subclinical seizures are common in critically ill children and are best detected by continuous EEG (cEEG) monitoring. Timely detection of seizures requires pediatric intensive care unit (PICU) physicians to identify patients at risk of seizures and request cEEG monitoring. A recent consensus statement from t...
journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-020-01053-8
更新日期:2020-07-21 00:00:00
abstract:INTRODUCTION:Syringohydromyelia associated with supratentorial space-occupying lesion has rarely been reported. We present a 28-year-old woman was admitted to the hospital with head and neck pain. Upon examination, there was only left central facial paralisia, with no evidence of papilledema. METHODS AND RESULTS:Crani...
journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1385/NCC:2:1:051
更新日期:2005-01-01 00:00:00
abstract::Computed tomography (CT) scan of the brain transitioned clinical neurology from the educated-guess world to the real computer-age world. One of the first CT scans-published by the British neuroradiologist James Ambrose-showed an intracranial hemorrhage and also suggested the use of iodine to demonstrate abnormal blood...
journal_title:Neurocritical care
pub_type: 历史文章,杂志文章
doi:10.1007/s12028-017-0495-3
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Global cerebral edema (GCE) is a manifestation of early brain injury (EBI) after subarachnoid hemorrhage (SAH) and is an independent risk factor for poor outcome. The lack of a quantitative method to measure GCE limits the study of its pathophysiology. The goal of this study is to develop a quantitative surr...
journal_title:Neurocritical care
pub_type: 临床试验,杂志文章
doi:10.1007/s12028-015-0229-3
更新日期:2016-08-01 00:00:00
abstract:INTRODUCTION:Over-the-counter herbal and alternative medicines are classified as dietary supplements and, unlike drugs, are not rigorously regulated by the United States Food and Drug Administration. Their potential adverse effects are often poorly characterized. METHOD:Red clover, dong quai, and Siberian ginseng are ...
journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-007-0075-z
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:Patients with acute neurological illness may be hypercatabolic. The Harris-Benedict Equation (HBE) is used to estimate energy needs in acute stroke. A "stress factor" for stroke does not exist, and it is not known if the HBE accurately estimates the energy expenditure needs in acute ischemic or hemorrhagic...
journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1385/NCC:1:3:331
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Impaired cerebrovascular reactivity (CR) has been reported to be associated with adverse outcome in patients with aneurysmal subarachnoid hemorrhage (aSAH). However, CR may be determined using different paradigms and it is unclear, which measurement method most suitable reflects the clinical course or is abl...
journal_title:Neurocritical care
pub_type: 杂志文章,评审
doi:10.1007/s12028-009-9287-8
更新日期:2010-04-01 00:00:00
abstract:BACKGROUND:This prospective study of an innovative non-invasive ultrasonic cerebrovascular autoregulation (CA) monitoring method is based on real-time measurements of intracranial blood volume (IBV) reactions following changes in arterial blood pressure. In this study, we aimed to determine the clinical applicability o...
journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-018-0569-x
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Little data exist regarding the practice of sodium management in acute neurologically injured patients. This study describes the practice variations, thresholds for treatment, and effectiveness of treatment in this population. METHODS:This retrospective, multicenter, observational study identified 400 ICU p...
journal_title:Neurocritical care
pub_type: 杂志文章,多中心研究
doi:10.1007/s12028-016-0343-x
更新日期:2017-10-01 00:00:00
abstract::Recombinant activated factor VII (rFVIIa, NovoSeven, NovoNordisc, Danemark) has been approved for the treatment of patients with hemophilia with inhibitors, further indications, at least in some countries, include the treatment of factor VII deficiency and Glanzmann thrombasthenia refractory to conventional therapy. A...
journal_title:Neurocritical care
pub_type: 杂志文章,评审
doi:10.1007/s12028-007-0006-z
更新日期:2007-01-01 00:00:00
abstract:INTRODUCTION:Bacterial meningitis is associated with a high mortality and a high incidence of neurological sequelae. Parainfectious vasculitis leading to ischemic brain damage is a known complication of bacterial meningitis but its treatment is uncertain. METHODS AND RESULTS:We report the case of a 53-year-old man wit...
journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1385/NCC:4:3:237
更新日期:2006-01-01 00:00:00
abstract::Drug shortages have become all too familiar in the health care environment, with over 200 drugs currently on shortage. In the wake of Hurricane Maria in September 2017, hospitals across the USA had to quickly and creatively adjust medication preparation and administration techniques in light of decreased availability ...
journal_title:Neurocritical care
pub_type: 杂志文章,评审
doi:10.1007/s12028-019-00730-7
更新日期:2020-02-01 00:00:00
abstract::A growing body of clinical literature emphasizes the impact of cerebral edema in early brain injury following aneurysmal subarachnoid hemorrhage (aSAH). Aneurysm rupture itself initiates global cerebral edema in up to two thirds of cases. Although cerebral edema is not a universal feature of aSAH, it portends a poor c...
journal_title:Neurocritical care
pub_type: 杂志文章,评审
doi:10.1007/s12028-016-0354-7
更新日期:2017-04-01 00:00:00
abstract::In the original article, Figure 5 has incorrect EEG images and the corrected version is shown below. ...
journal_title:Neurocritical care
pub_type: 杂志文章,已发布勘误
doi:10.1007/s12028-020-00981-9
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Highly asymmetric clinical signs in a patient suggest the need for caution in making the diagnosis of Guillain-Barré Syndrome (GBS). METHODS:Case report and literature review. We present a case of strictly unilateral left third cranial nerve palsy in a patient with GBS, review other highly asymmetrical cran...
journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1385/NCC:1:4:461
更新日期:2004-01-01 00:00:00
abstract::Sleep is fundamental for everyday functioning, yet it is often negatively impacted in critically ill patients by the intensive care setting. With a focus on the neurological intensive care unit (NeuroICU), this narrative review summarizes methods of measuring sleep and addresses common causes of sleep disturbance in t...
journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-019-00795-4
更新日期:2020-04-01 00:00:00
abstract:INTRODUCTION:Relative adrenal insufficiency has been shown to occur in the settings of critical illness and septic shock, impairing the body's ability to respond to stress. Studies have demonstrated that the treatment of adrenal insufficiency (AI) results in shock reversal, hemodynamic stability, and a subsequent decre...
journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-007-9003-5
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Cerebral edema and raised intracranial pressure are common problems in neurological intensive care. Osmotherapy, typically using mannitol or hypertonic saline (HTS), has become one of the first-line interventions. However, the literature on the use of these agents is heterogeneous and lacking in class I stud...
journal_title:Neurocritical care
pub_type: 杂志文章
doi:10.1007/s12028-010-9477-4
更新日期:2011-04-01 00:00:00