Elimination of Fc receptor binding of human immunoglobulin G in immunofluorescence assays for herpes simplex virus antibodies.

Abstract:

:The binding of human immunoglobulin G by Fc receptors in herpes simplex virus (HSV)-infected cells can cause false-positive interpretations in the immunofluorescence test for HSV antibody. When the infected cell smears were treated with 10% glacial acetic acid for 5 min and rinsed in phosphate-buffered saline before the immunofluorescence test was performed, the Fc receptors were completely inactivated, resulting in a reliable method for HSV antibody detection.

journal_name

J Clin Microbiol

authors

Gallo D

doi

10.1128/JCM.24.4.672-674.1986

subject

Has Abstract

pub_date

1986-10-01 00:00:00

pages

672-4

issue

4

eissn

0095-1137

issn

1098-660X

journal_volume

24

pub_type

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