Receptors on individual neurones.

abstract：:Agonist-induced endocytosis and recycling of G protein-coupled receptors contributes to desensitization and resensitization of the receptors. In this study, we have used fluorescence immunohistochemistry, confocal microscopy and digital image analysis to quantify the proportion of receptor in the cytoplasm and on the ...

journal_title：Neuroscience

authors： Southwell BR,Seybold VS,Woodman HL,Jenkinson KM,Furness JB

更新日期：1998-12-01 00:00:00

abstract：:Recent studies suggest that neurons containing adrenocorticotropin and catecholamines are localized to similar areas of the brain. In this immunocytochemical study, the distributions of neurons and terminals containing adrenocorticotropin and tyrosine hydroxylase, the first enzyme in the catecholamine biosynthetic pat...

journal_title：Neuroscience

authors： Baker H,Ruggiero DA,Alden S,Anwar M,Reis DJ

更新日期：1986-02-01 00:00:00

abstract：:Protection of substantia nigra (SN) dopaminergic (DA) neurons by neurotrophic factors (NTFs) is one of the promising strategies in Parkinson's disease (PD) therapy. A major clinical challenge for NTF-based therapy is that NTFs need to be delivered into the brain via invasive means, which often shows limited delivery e...

journal_title：Neuroscience

authors： Pang Y,Lin S,Wright C,Shen J,Carter K,Bhatt A,Fan LW

更新日期：2016-03-24 00:00:00

abstract：:The synaptic organization of terminals originating either from the spinal cord (spinothalamic) or from the dorsal column nuclei (lemniscal) was investigated in the ventrobasal complex of the rat thalamus. Wheatgerm agglutinin conjugated to horseradish peroxidase was used as an anterogradely transported axonal tracer, ...

journal_title：Neuroscience

authors： Ma W,Peschanski M,Ralston HJ 3rd

更新日期：1987-09-01 00:00:00

abstract：:GABAB receptors affect short-term signalling in various cell types. However, nothing is known about possible long-term effects on transcription. To analyse such effects in the CNS, we studied GABAB receptor-mediated gene regulation in primary cultures of cerebellar granule neurons. Transcription was followed using a c...

journal_title：Neuroscience

authors： Barthel F,Kienlen Campard P,Demeneix BA,Feltz P,Loeffler JP

更新日期：1996-01-01 00:00:00

abstract：:Up-regulation of proBDNF in ischemic brain and the detrimental role of proBDNF on cellular survival has already been established. We propose that the up-regulated proBDNF may trigger the harmful events and evoke a secondary ischemic damage after ischemia. This study aimed to establish the neuroprotective effects of an...

journal_title：Neuroscience

authors： Rahman M,Luo H,Bobrovskaya L,Zhou XF

更新日期：2020-10-15 00:00:00

abstract：:The hemispheric content of dopamine and its metabolites in the frontal cortex, caudatus putamen and nucleus accumbens septi was evaluated in relation to behavioral lateralization assessed by paw preference. Three groups of C3H/He mice were selected on the basis of their performance in the paw preference test (left-han...

journal_title：Neuroscience

authors： Cabib S,D'Amato FR,Neveu PJ,Deleplanque B,Le Moal M,Puglisi-Allegra S

更新日期：1995-01-01 00:00:00

abstract：:Animal studies have revealed that chronic stress shifts cognitive strategies from the flexible goal-directed action to the simple and rigid habit action. In addition, stress-induced atrophy in the prefrontal cortex and dorsomedial striatum which are involved in the goal-directed action and hypertrophy of the dorsolate...

journal_title：Neuroscience

authors： Ohira H,Matsunaga M,Kimura K,Murakami H,Osumi T,Isowa T,Fukuyama S,Shinoda J,Yamada J

更新日期：2011-10-13 00:00:00

abstract：:Neuroglobin (Ngb) is a tissue globin specifically expressed in neurons. Our laboratory and others have shown that Ngb overexpression protects neurons against hypoxia/ischemia, but the underlying mechanisms remain poorly understood. Recent studies demonstrate that hypoxia/ischemia induces a multitude of spatially and t...

journal_title：Neuroscience

authors： Yu Z,Liu J,Guo S,Xing C,Fan X,Ning M,Yuan JC,Lo EH,Wang X

更新日期：2009-08-18 00:00:00

abstract：:Orientation tuning of 271 neurons of the cat visual cortex (area 17) was studied with a light bar flashing in the receptive field. Under different conditions, 27-57% of units were found to have double-orientation tuning: they demonstrated the main preferred orientation and an additional preferred orientation. The stat...

journal_title：Neuroscience

authors： Shevelev IA,Lazareva NA,Novikova BV,Tikhomirov AS,Sharaev GA

更新日期：1994-08-01 00:00:00

abstract：:Monoclonal antibodies SMI-31 and 150 recognize phosphorylation epitopes on microtubule-associated protein 1B that have been shown to be developmentally down-regulated in the nervous system. We have used these antibodies to establish changes in the pattern of expression of their epitopes on microtubule-associated prote...

journal_title：Neuroscience

authors： Bush MS,Tonge DA,Woolf C,Gordon-Weeks PR

更新日期：1996-07-01 00:00:00

abstract：:Converging evidence in schizophrenia suggests prefrontal cortical neuronal deficits that correlate with exaggerated subcortical dopamine (DA) functions: Excitotoxic lesion of the ventral hippocampus (VH) in neonatal rats is widely considered a putative animal model of schizophrenia as they lead to characteristic post-...

journal_title：Neuroscience

authors： Bhardwaj SK,Beaudry G,Quirion R,Levesque D,Srivastava LK

更新日期：2003-01-01 00:00:00

abstract：:We showed that hypothermic preconditioning (HPC) increased survival of Purkinje neurons in rat cerebellar slices after oxygen-glucose deprivation (OGD). HPC also reduced the OGD-increased expression of high mobility group I (Y) proteins, a transcription factor that can enhance inducible nitric oxide synthase (iNOS) ex...

journal_title：Neuroscience

authors： Yuan HB,Huang Y,Zheng S,Zuo Z

更新日期：2006-10-13 00:00:00

abstract：:Similar to kappa-opioids, nociceptin/orphanin FQ (OFQ) exerts anti-mu-opioid actions. This may involve interactions within the circuitry controlling 5-HT neurons in the dorsal raphe nucleus (DRN) that project to the nucleus accumbens (NAcc). To test this hypothesis, we compared the effects of OFQ and kappa-opioids on ...

journal_title：Neuroscience

authors： Tao R,Ma Z,Thakkar MM,McCarley RW,Auerbach SB

更新日期：2007-06-15 00:00:00

abstract：:The midbrain periaqueductal gray (PAG) is the area promoting emotional motor responses, reproductive behaviors and analgesia. Recent studies suggest that neurons in the PAG may be crucial for regulating the micturition reflex in both experimental animals and humans. We examined single neuronal activities in the PAG an...

journal_title：Neuroscience

authors： Liu Z,Sakakibara R,Nakazawa K,Uchiyama T,Yamamoto T,Ito T,Hattori T

更新日期：2004-01-01 00:00:00

abstract：:Alzheimer's disease (AD), the most common form of dementia in the elderly, is characterized by the presence of extracellular plaques composed of amyloid β (Aβ) peptides and intracellular tau aggregates. The plaques are surrounded by microglia, the brain's resident immune cells, which likely participate in the clearanc...

journal_title：Neuroscience

authors： Gyoneva S,Swanger SA,Zhang J,Weinshenker D,Traynelis SF

更新日期：2016-08-25 00:00:00

abstract：:Following intracerebral hemorrhage (ICH), high-mobility group box 1 protein (HMGB1) may promote vascular remodeling. Whether HMGB1 supports angiogenesis after ICH is unclear, as are the receptors and downstream signaling pathway(s) involved. We used the rat model of collagenase-induced ICH to determine whether HMGB1 a...

journal_title：Neuroscience

authors： Lei C,Zhang S,Cao T,Tao W,Liu M,Wu B

更新日期：2015-06-04 00:00:00

abstract：:Current cognitive models suggest that the processing of dynamic facial attributes, including social signals such as gaze direction and facial expression, involves the superior temporal sulcus, whereas the processing of invariant facial structure such as the individuals' identity involves the fusiform face area. Where ...

journal_title：Neuroscience

authors： Iaria G,Fox CJ,Waite CT,Aharon I,Barton JJ

更新日期：2008-08-13 00:00:00

abstract：:Dopamine/cAMP signaling has been reported to mediate behavioral responses related to drug addiction. It also modulates the plasticity and firing properties of medium spiny neurons (MSNs) in the nucleus accumbens (NAc), although the effects of cAMP signaling on the resting membrane potential (RMP) of MSNs has not been ...

journal_title：Neuroscience

authors： Podda MV,Riccardi E,D'Ascenzo M,Azzena GB,Grassi C

更新日期：2010-05-19 00:00:00

abstract：:Agmatine, the decarboxylated metabolite of l-arginine, is considered to be a novel putative neurotransmitter. Recent studies have demonstrated that endogenous agmatine may directly participate in the processes of spatial learning and memory. Agmatine-immunoreactivity has been observed within synaptic terminals of asym...

journal_title：Neuroscience

authors： Seo S,Liu P,Leitch B

更新日期：2011-09-29 00:00:00

abstract：:Adverse environments during early life may lead to different neurophysiological and behavioral consequences, including depression and learning and memory deficits that persist into adulthood. Previously, we demonstrated that exposure to an enriched environment during adolescence mitigates the cognitive impairment obse...

journal_title：Neuroscience

authors： Cordier JM,Aguggia JP,Danelon V,Mir FR,Rivarola MA,Mascó D

更新日期：2021-01-15 00:00:00

abstract：:I have prepared a number of monoclonal antibodies to chromaffin cell membranes. One of these antibodies recognizes a number of antigenically related proteins that are present in all tissues examined. In the adrenal, these proteins are completely excluded from chromaffin granules but are present in other subcellular me...

journal_title：Neuroscience

authors： Pruss RM

更新日期：1987-07-01 00:00:00

abstract：:A qualitative and quantitative immunohistochemical study of cholinergic systems in the human hippocampal formation was performed with an antibody against choline acetyltransferase. Four control subjects and six patients with Alzheimer's disease, matched for age and post-mortem delay, were examined. Immunoreactive nerv...

journal_title：Neuroscience

authors： Ransmayr G,Cervera P,Hirsch E,Ruberg M,Hersh LB,Duyckaerts C,Hauw JJ,Delumeau C,Agid Y

更新日期：1989-01-01 00:00:00

abstract：:In a previous study, it was shown that populations of climbing fibers, derived from the inferior olivary complex (IOC) contain the peptide corticotropin releasing factor (CRF) and that the expression of this peptide in climbing fibers could be modulated by the level of activity in olivary afferents. The intent of this...

journal_title：Neuroscience

authors： Tian JB,King JS,Bishop GA

更新日期：2008-04-22 00:00:00

abstract：:Functional imaging studies have implicated the hippocampus and parahippocampal gyrus in cue-guided spatial navigation, but also many other regions. Furthermore, little is known about de-activations that take place during performance of navigation tasks, something that is of interest given that the hippocampus is a com...

journal_title：Neuroscience

authors： Salgado-Pineda P,Landin-Romero R,Pomes A,Spanlang B,Sarró S,Salvador R,Slater M,McKenna PJ,Pomarol-Clotet E

更新日期：2017-09-01 00:00:00

abstract：:Foetal mouse hippocampal primordia from mice homozygous for the Thy-1.1 allele were transplanted into the hippocampal region of adult histocompatible mice, homozygous for the Thy-1.2 allele. After survival periods of two months to one year the transplants consisted of a discrete tissue mass, well fused with the host, ...

journal_title：Neuroscience

authors： Zhou CF,Raisman G,Morris RJ

更新日期：1985-12-01 00:00:00

abstract：:Flies acquire information about self-rotation via Coriolis forces detected by their moving halteres. Information processing in the haltere system was analysed by exploiting the method of simulating rotational stimuli by vibrating the fly's body and simultaneously observing compensatory head and wing reactions. Althoug...

journal_title：Neuroscience

authors： Nalbach G

更新日期：1994-07-01 00:00:00

abstract：:Increased levels of preproenkephalin mRNA in spinal cord neurons induced by peripheral tissue inflammation were examined using in situ hybridization histochemistry. In addition, in situ hybridization histochemistry was combined with immunocytochemistry to determine whether increases in preproenkephalin mRNA were co-lo...

journal_title：Neuroscience

authors： Noguchi K,Dubner R,Ruda MA

更新日期：1992-01-01 00:00:00

abstract：:Brain responses to discrete short sounds have been studied intensively using the event-related potential (ERP) method, in which the electroencephalogram (EEG) signal is divided into epochs time-locked to stimuli of interest. Here we introduce and apply a novel technique which enables one to isolate ERPs in human elici...

journal_title：Neuroscience

authors： Poikonen H,Alluri V,Brattico E,Lartillot O,Tervaniemi M,Huotilainen M

更新日期：2016-01-15 00:00:00

abstract：:Extensive studies have shown that a sports expert is superior to a sports novice in visually perceptual-cognitive processes of sports scene information, however the attentional and neural basis of it has not been thoroughly explored. The present study examined whether a sport expert has the attentional superiority on ...

journal_title：Neuroscience

authors： He M,Qi C,Lu Y,Song A,Hayat SZ,Xu X

更新日期：2018-05-21 00:00:00