Abstract:
:Hepatocyte-specific contrast media are gadolinium chelates that are taken up by hepatocytes and partially cleared via the biliary tree. The absence of lesional uptake of the contrast media in the hepatobiliary phase is a marker of either the absence of hepatocytes or of poorly functioning, neoplastic hepatocytes. Uptake of the contrast media in the hepatobiliary phase, whether equal to or greater than background liver, reflects the presence of hepatocytes but does not equate to absence of neoplasia. Accurate diagnosis of liver lesions utilizing hepatocyte-specific contrast media requires an understanding of the mechanisms of uptake and clearance of the contrast media to avoid misdiagnosis. In this review we discuss the mechanisms of hepatocellular transport of hepatocyte-specific contrast media and utilize an understanding of those mechanisms to discuss the imaging appearance of a subset of hepatocellular lesions that can be seen in the pediatric and young adult liver. We pay particular attention to lesions that appear iso- to hyperintense in the hepatobiliary phase but have the potential for adverse clinical outcomes. We also discuss strategies for identifying these lesions.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Trout AT,Towbin AJ,Smith EA,Gupta A,Dillman JRdoi
10.1007/s00247-018-4108-xsubject
Has Abstractpub_date
2018-08-01 00:00:00pages
1245-1255issue
9eissn
0301-0449issn
1432-1998pii
10.1007/s00247-018-4108-xjournal_volume
48pub_type
杂志文章,评审abstract::We present an unusual case of severe hydranencephaly in a term infant who presented with the following additional unique features, which were discovered on CT, MRI and MR angiography examinations: (1) occlusion of the bilateral posterior cerebral arteries, (2) absence of the occipital lobes, (3) an ovoid calcified mas...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-010-1894-1
更新日期:2011-02-01 00:00:00
abstract::Malignant metastasis to the breast, rare in adults, has occurred in children from hematologic malignancies and from neuroblastoma and rhabdomyosarcoma. We report a case of bilateral breast metastases in a 14-year-old girl with a prior nephrectomy for renal cell carcinoma; the breast masses were the first sign of recur...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050111
更新日期:1997-03-01 00:00:00
abstract::Isolated, well-differentiated ectopic cerebellar tissue is extremely rare, with only eight cases in the literature. We describe a unique case of histopathologically proven ectopic cerebellar tissue presenting as a discrete extra-axial mass in the posterior cranial fossa. We describe the clinical, CT and MRI findings, ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-012-2411-5
更新日期:2012-11-01 00:00:00
abstract:BACKGROUND:Knowledge of the synovial and tenosynovial appearance of the clinically non-arthritic symptomatic juvenile wrist using contrast-enhanced magnetic resonance imaging (MRI) is sparse. OBJECTIVES:To analyze contrast-enhanced MRI findings of the clinically non-inflamed symptomatic pediatric wrist, focusing on th...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-020-04739-5
更新日期:2020-09-01 00:00:00
abstract::Omental cyst is a rare lesion occurring primarily during childhood and young adulthood. It is closely related to mesenteric and retroperitoneal cysts, all conditions most likely being of congenital or benign neoplastic lymphatic origin. Omental cysts usually present as abdominal distention of long duration, less frequ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01006901
更新日期:1975-06-13 00:00:00
abstract:BACKGROUND:Knowledge of ovarian volume is important for diagnostic evaluations; however, normal ovarian volume studies on children and adolescents are lacking. OBJECTIVE:This study aimed to analyze age-specific ovarian volume and identify the diverse factors that contribute to ovarian diagnoses. MATERIALS AND METHODS...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-019-04469-3
更新日期:2019-09-01 00:00:00
abstract::Intrathoracic rib is a rare congenital anomaly that is usually discovered incidentally. It represents a benign lesion but can mimic intrathoracic pathology, so it is important to recognize it to prevent further unnecessary investigation or intervention. Typically, the classic appearance allows diagnosis with confidenc...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-008-0881-2
更新日期:2008-09-01 00:00:00
abstract::The Computed Tomography (CT) appearance of a pelvic haemangioma involving the rectum in two children, one with the Vater association and one with Klippel-Trenaunay syndrome, is described. Both cases complained of painless rectal bleeding and the diagnosis was suggested by the presence of pelvic phleboliths on the plai...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02387639
更新日期:1989-01-01 00:00:00
abstract::In hypertrophic pyloric stenosis (HPS), prompt pyloromyotomy is, in general, the treatment of choice. There has been no information available as to the natural history of the pyloric tumour. We present four infants with medically treated HPS who were followed by sonography to observe the anatomical changes that occur ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050325
更新日期:1998-03-01 00:00:00
abstract:BACKGROUND:Inferior vena cava (IVC) filter placement in children has been described in literature, but there is variability with regard to their indications. No nationally representative study has been done to compare practice patterns of filter placements at adult and children's hospitals. OBJECTIVE:To perform a nati...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-017-4001-z
更新日期:2018-02-01 00:00:00
abstract::We performed 25 percutaneous fine needle biopsies (PFNB) on pediatric patients during a 3-year period. Of 17 patients with proven malignancies, PFNB was true positive in 16 and false negative in one. In nine patients with benign or inflammatory disorders, there were three true positives and six false negatives. There ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02388363
更新日期:1985-01-01 00:00:00
abstract::A case of the Hajdu-Cheney syndrome in a 15 year old boy is described. The manifestations were: 1. isiopathic progressive acro-osteotions; 2. mutiple cranio-skeletal abnormalities; and 3. polycystic kidneys complicated by a rapidly progressive glomerulonephritis. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF00973535
更新日期:1977-09-01 00:00:00
abstract:OBJECTIVE:The purpose of this paper is to review and categorize the CT appearances of primary and secondary intraperitoneal neoplasms in children. MATERIALS AND METHODS:We retrospectively reviewed the CT images of 14 cases of intraperitoneal neoplasms. They were reviewed for bowel wall thickening, mesenteric nodules, ...
journal_title:Pediatric radiology
pub_type: 杂志文章,多中心研究
doi:10.1007/s002470050363
更新日期:1998-05-01 00:00:00
abstract::Rare earth filters are known to reduce radiation dose in radiological investigations. The present investigation used Er and Sm filters that were selected because of their chemical stability and ability to withstand prolonged exposure to the atmosphere. They were used in a comparison with a conventional aluminium filte...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01601887
更新日期:1984-01-01 00:00:00
abstract::Purpose. To determine the incidence of neurologic complications of cerebral angiography in children with moyamoya syndrome (MMS) as compared to children without MMS. Materials and methods. One-hundred-ninety consecutive cerebral angiograms obtained in 152 children were evaluated. Sixty of these angiograms were obtaine...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050474
更新日期:1998-11-01 00:00:00
abstract::Pseudotumoral cystitis is an unusual lesion and since it may be confused with rhabdomyosarcoma, knowledge of its existence is important. We report eight cases. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::Certain misleading appearances are peculiar to pediatric uroradiology. The most frequently encountered pitfalls are related to the bladder, to vesicoureteral reflux, and to the duplicated collecting system. The bi-chambered nature of the child's bladder, and the rapid settling of contrast material to the most dependen...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01644339
更新日期:1980-09-01 00:00:00
abstract::The human immunodeficiency virus (HIV) epidemic seems largely controlled by anti-retroviral treatment with resultant large numbers of children growing up with the disease on long-term treatment, placing them at higher risk to develop HIV-related brain injury, ongoing cognitive impairment and treatment-related neurolog...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s00247-018-4310-x
更新日期:2019-05-01 00:00:00
abstract::Abstract Papillary thyroid carcinoma is rare in children. Its clinical manifestation may deviate from that observed in adult patients. We present a 14-year-old girl with papillary thyroid carcinoma. We then discuss various distinctive sonographic signs that may aid diagnosis, and we discuss differences in clinical fea...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-011-2189-x
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Air enema under fluoroscopy is a well-accepted procedure for the treatment of childhood intussusception. However, the reported radiation doses of pneumatic reduction with conventional fluoroscopy units have been high in decades past. OBJECTIVE:To compare current radiation doses at our institution to past do...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-014-3218-3
更新日期:2015-04-01 00:00:00
abstract::Gorham's disease may develop in any region of the skeleton, but shows a predilection for the bones of the shoulders and pelvic girdles. Less frequently, the disease may involve the spine, and it is the proximity to the spinal cord which may worsen the patient's outcome. We report the clinical outcomes of two children ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02012113
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:Sonography has been used to predict pneumatic reduction outcome in children with intussusception. OBJECTIVE:To assess the prognostic significance of fluid between the intussusceptum and intussuscepiens with respect to reduction outcome, lead point or necrosis. MATERIALS AND METHODS:Sonograms of children wi...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-010-1931-0
更新日期:2011-06-01 00:00:00
abstract::We report the US and MR appearances in a case of persistent Müllerian duct syndrome, a rare form of inherited male pseudohermaphroditism characterised by the presence of uterus and fallopian tubes in a normally virilised 46XY male. ...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/s002470050484
更新日期:1998-11-01 00:00:00
abstract::One hundred barium meal examinations performed on infants of less than 4 months of age are reviewed. All the infants presented with vomiting as a major symptom and the diagnosis remained in doubt following the initial clinical assessment. Fifty seven per cent of the examinations showed an abnormality of which 45% were...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF01625813
更新日期:1984-01-01 00:00:00
abstract::We report a case of multifocal metachronous giant cell tumor (GCT) that involved the fibula, tibia, and sacrum of a 15-year-old boy. Multifocal GCT of bone presenting in children is an exceedingly rare phenomenon; however, there is evidence that multifocal GCT presents, on average, at a younger age than solitary GCT. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-004-1346-x
更新日期:2005-04-01 00:00:00
abstract::A 4-year-old boy with bilateral optic sheath enlargement and progressive optic atrophy and blindness is presented. Computed tomography demonstrated hydrocephalus and enlargement of the optic nerve sheath complex. The child died during an attempted repair of hypoplastic atrioventricular valves. Autopsy demonstrated a p...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050518
更新日期:1998-12-01 00:00:00
abstract::Clavicle fractures are the most common bony injury that occurs during the delivery process. We present a case of medial clavicular physeal fracture mimicking sternoclavicular dislocation diagnosed by ultrasound (US) in a neonate. The infant presented to our clinic at 12 days old with improving left upper extremity pse...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s00247-019-04583-2
更新日期:2020-04-01 00:00:00
abstract::Dideoxyinosine (ddI) is a widely used antiretroviral agent in treatment of HIV infection. Pancreatitis is a serious side effect. Two cases are reported, one with rapid development of a pseudocyst. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/s002470050099
更新日期:1997-02-01 00:00:00
abstract::Aspergillus is the most common fungal infectious pathogen in immunocompromised individuals, but the diagnosis is hard to obtain. In a patient with spinal cord involvement, MRI proved to be excellent. ...
journal_title:Pediatric radiology
pub_type: 杂志文章
doi:10.1007/BF02013175
更新日期:1990-01-01 00:00:00
abstract::Osteopathia striata with cranial sclerosis (OS-CS) is a specific bone dysplasia manifested by hypertelorism, flat nasal bridge, frontal bossing, large head, hypoplastic maxilla, palate anomalies, chronic otitis media, hearing deficits, nasal obstruction, and neurological changes of deafness, facial palsy, ophthalmople...
journal_title:Pediatric radiology
pub_type: 杂志文章,评审
doi:10.1007/BF02017665
更新日期:1994-01-01 00:00:00