Is Italian population protected from Poliovirus? Results of a seroprevalence survey in Florence, Italy.

abstract：:Rapid production of influenza vaccine antigen is an important challenge when a new pandemic occurs. Production of recombinant antigens in plants is a quick, cost effective and up scalable new strategy for influenza vaccine production. In this study, we have characterized a recombinant influenza haemagglutinin antigen ...

journal_title：Human vaccines & immunotherapeutics

authors： Jul-Larsen Å,Madhun AS,Brokstad KA,Montomoli E,Yusibov V,Cox RJ

更新日期：2012-05-01 00:00:00

abstract：:Hepatitis B vaccine is the most effective strategy to control hepatitis B virus (HBV) infection and disease. It is considered that an anti-HBs (antibodies against HBV surface antigen) titer >10 mIU/ml, measured shortly after a complete vaccination schedule, provides protection against infection. Approximately 4-10% of...

journal_title：Human vaccines & immunotherapeutics

authors： Cassaniti I,Calarota SA,Adzasehoun KM,Chiesa A,Comolli G,Parea M,Baldanti F

更新日期：2016-11-01 00:00:00

abstract：:Meningococcal serogroup B (MenB) is the predominant cause of invasive meningococcal disease in the United States, with older adolescents and young adults attending college at increased risk. Notably, MenB caused all meningococcal disease outbreaks at US colleges between 2011 and 2018. MenB disease is vaccine-preventab...

journal_title：Human vaccines & immunotherapeutics

authors： McDaniel A,Dempsey A,Srivastava A

更新日期：2019-01-01 00:00:00

abstract：:Background: We performed a systematic review to evaluate factors affecting uptake of rotavirus vaccine amongst physicians, parents and health system. Methods: We identified 15 studies that met the inclusion criteria from 790 screened studies published between Jan 2005 to Jan 2016. Results: Perceived severity of rotavi...

journal_title：Human vaccines & immunotherapeutics

authors： Apte A,Roy S,Bavdekar A,Juvekar S,Hirve S

更新日期：2018-01-01 00:00:00

abstract：:The purpose of this study is to mine CAR-T patents and therapies under development, to design a landscape of the sector and to understand key therapy segments and their current trends. The study analyzed the entire market, consisting of 1624 patent families and 509 biologics under development, to depict an overview of...

journal_title：Human vaccines & immunotherapeutics

authors： Picanco-Castro V,Gonçalves Pereira C,Swiech K,Ribeiro Malmegrim KC,Tadeu Covas D,Silveira Porto G

更新日期：2020-06-02 00:00:00

abstract：AIM:Pertussis continues to be a common worldwide infection in pediatric and adult populations. We aimed to study epidemiological and clinical characteristics of infants and children admitted for pertussis to a tertiary-care hospital and to investigate the risk factors for pediatric intensive care unit (PICU) admission....

journal_title：Human vaccines & immunotherapeutics

authors： Di Camillo C,Vittucci AC,Antilici L,Ciarlitto C,Linardos G,Concato C,Lancella L,Villani A

更新日期：2020-08-05 00:00:00

abstract：:In patients undergoing immunotherapy, the quality of the immune response is reduced, which may negatively affect the efficacy of vaccination. This study was conducted in order to evaluate the efficacy of the hepatitis B virus (HBV) vaccine in patients using immunomodulators. Seronegative patients for HBV who were usin...

journal_title：Human vaccines & immunotherapeutics

authors： Haykir Solay A,Eser F

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:The prevalence of occult hepatitis B (HB) infection (OBI) in HB-vaccinated diabetic children has not yet been tested. Here, we aimed to determine the prevalence of OBI among HB-vaccinated children and adolescents with insulin-dependent diabetes mellitus (IDDM). RESULTS:Eighty-seven (51.2%) children had a ti...

journal_title：Human vaccines & immunotherapeutics

authors： Elrashidy H,El-Didamony G,Elbahrawy A,Hashim A,Alashker A,Morsy MH,Elwassief A,Elmestikawy A,Abdallah AM,Mohammad AG,Mostafa M,George NM,Abdelhafeez H

更新日期：2014-01-01 00:00:00

abstract：:Background: To assess the knowledge and attitudes of middle school students toward vaccination, we measured their understanding of vaccine safety and effectiveness, expectations for communication with heath care providers, and their desired role in the vaccination decision-making process. Methods: A cross-sectional, s...

journal_title：Human vaccines & immunotherapeutics

authors： Herman R,McNutt LA,Mehta M,Salmon DA,Bednarczyk RA,Shaw J

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:We studied completeness and timeliness of vaccination and determinants for low and delayed uptake in children born between 2008 and 2009 in Zhejiang province in eastern China. METHODS:We used data from a cross-sectional cluster survey conducted in 2011, which included 1146 children born from 1 Jan 2008 to 3...

journal_title：Human vaccines & immunotherapeutics

authors： Hu Y,Chen Y,Guo J,Tang X,Shen L

更新日期：2014-01-01 00:00:00

abstract：:In Chronic Myeloid Leukemia (CML), standard treatment consists of modern tyrosine-kinase inhibitors (TKI). Nevertheless, there is evidence that immune responses against leukemia-associated antigens (LAA) may play an important role in disease control. Dendritic cell (DC)- based immunotherapy is able to induce T cell re...

journal_title：Human vaccines & immunotherapeutics

authors： Flörcken A,Kopp J,Kölsch U,Meisel C,Dörken B,Pezzutto A,Westermann J

更新日期：2016-05-03 00:00:00

abstract：:Paralytic poliomyelitis is a disease that became a public health issue at the beginning of the twentieth century and was more or less eliminated in developed countries by the early 1970s. The Global Polio Eradication Initiative of WHO has now eradicated endemic polio from all but three countries although re-introducti...

journal_title：Human vaccines & immunotherapeutics

authors： Minor P

更新日期：2014-01-01 00:00:00

abstract：:In order to analyze the effect of EV71 vaccination on the incidence of encephalitis in patients with HFMD, 292 cases were vaccinated, and 2,486 cases were not vaccinated which were collected in 2018 and 2019. It shows that the incidence rate of encephalitis in vaccinated patients was significantly lower than that in n...

journal_title：Human vaccines & immunotherapeutics

authors： Li J,Yin X,Lin A,Nie X,Liu L,Liu S,Li N,Wang P,Song S,Wang S,Xu D

更新日期：2021-01-31 00:00:00

abstract：:Nationally, human papillomavirus (HPV) vaccination rates fall short of the Healthy People 2020 goal of 80% completion. Although strategies to increase these rates exist, low rates persist. We used concept mapping with state-level stakeholders to better understand barriers and facilitators to HPV vaccination. Concept m...

journal_title：Human vaccines & immunotherapeutics

authors： Ryan G,Avdic L,Daly E,Askelson N,Farris PE,Shannon J,McRee AL,Hanson J,Kenyon DB,Seegmiller L

更新日期：2020-12-17 00:00:00

abstract：:Pertussis is one of the most prevalent vaccine-preventable diseases worldwide. The true infection rate is significantly higher than the reported incidence rate. An increased prevalence of pertussis in older populations has been found, mainly caused by waning immunity after vaccination. Vaccine-induced immunity differs...

journal_title：Human vaccines & immunotherapeutics

authors： Chen Z,He Q

更新日期：2017-04-03 00:00:00

abstract：:We conducted a national study of children's hospitals and neighboring general medical-surgical hospitals to examine their employee vaccination policies. Survey questions addressed health care personnel (HCP) influenza vaccination policies for the 2009-2010 (seasonal, H1N1) and 2010-2011 (H1N1 + seasonal = combined) in...

journal_title：Human vaccines & immunotherapeutics

authors： Danziger P,Davis MM

更新日期：2012-06-01 00:00:00

abstract：:Rabies is the most lethal zoonotic, vaccine-preventable viral disease in the world. Its treatment is complicated by insufficient vaccine supply and the requirement for four to five repeated injections, as commercially available inactivated rabies lack adjuvant and have low immunogenicity. In this study, we focused on ...

journal_title：Human vaccines & immunotherapeutics

authors： Ze L,Zonglin L,Ya'Nan W,Shaohui S,Huijuan Y,Wei C,Li W,Liao G

更新日期：2019-01-01 00:00:00

abstract：:Disseminated bacillus Calmette-Guérin (BCG) disease is a rare and serious adverse event following immunization (AEFI) with BCG. Here, we reported two cases of disseminated BCG disease in the same family and reviewed the literature to identify another 35 cases in China. The average age at onset was 3.7 ± 2.1 months amo...

journal_title：Human vaccines & immunotherapeutics

authors： Wang J,Wu QS,Jiang MB,Xu ZH

更新日期：2020-10-20 00:00:00

abstract：:The development of a successful vaccine, which should elicit a combination of humoral and cellular responses to control or prevent infections, is the first step in protecting against infectious diseases. A vaccine may protect against bacterial, fungal, parasitic, or viral infections in animal models, but to be effecti...

journal_title：Human vaccines & immunotherapeutics

authors： Zheng Z,Diaz-Arévalo D,Guan H,Zeng M

更新日期：2018-07-03 00:00:00

abstract：:Variations of post-translational modifications are important for stability and in vivo behavior of therapeutic antibodies. A recombinant humanized anti-cocaine monoclonal antibody (h2E2) was characterized for heterogeneity of N-linked glycosylation and disulfide bonds. In addition, charge heterogeneity, which is parti...

journal_title：Human vaccines & immunotherapeutics

authors： Kirley TL,Norman AB

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:In an era of hesitance to use vaccines, the importance of effective communication for increasing vaccine acceptance is well known. This study aimed to assess the impact of a three-day residential course concerning empathy and counselling abilities on patients' ratings of the level of empathy of physicians an...

journal_title：Human vaccines & immunotherapeutics

authors： Maurici M,Arigliani M,Dugo V,Leo C,Pettinicchio V,Arigliani R,Franco E

更新日期：2019-01-01 00:00:00

abstract：:Raising high titer antibodies in animals is usually performed by protein immunization, which requires the long and sometimes difficult step of production of the recombinant protein. DNA immunization is an alternative to recombinant proteins, only requiring the building of an eukaryotic expression plasmid. Thanks to ef...

journal_title：Human vaccines & immunotherapeutics

authors： Burgain A,Rochard A,Trollet C,Mazuet C,Popoff MR,Escriou V,Scherman D,Bigey P

更新日期：2013-10-01 00:00:00

abstract：:Control programs for emerging influenza are in urgent need of novel therapeutic strategies to mitigate potentially devastating threats from pathogenic strains with pandemic potential. Current vaccines and antivirals have inherent limitations in efficacy, especially with rapid evolutionary changes of influenza viruses....

journal_title：Human vaccines & immunotherapeutics

authors： Berry CM

更新日期：2018-03-04 00:00:00

abstract：:Psoriasis is a chronic, immune skin disease associated with significant morbidity. Development of psoriasis is influenced by numerous genes, one allele is HLA-CW*0602. Other genes and single nucleotide polymorphisms affect immunologic pathways and antimicrobial peptide synthesis. Dendritic cells initiate psoriasis by ...

journal_title：Human vaccines & immunotherapeutics

authors： Kaffenberger BH,Lee GL,Tyler K,Chan DV,Jarjour W,Ariza ME,Williams MV,Wong HK

更新日期：2014-01-01 00:00:00

abstract：:The programmed cell death protein 1 (PD1) is one of the checkpoints that regulates the immune response. Ligation of PD1 with its ligands PDL1 and PDL2 results in transduction of negative signals to T-cells. PD1 expression is an important mechanism contributing to the exhausted effector T-cell phenotype. The expression...

journal_title：Human vaccines & immunotherapeutics

authors： Kwok G,Yau TC,Chiu JW,Tse E,Kwong YL

更新日期：2016-11-01 00:00:00

abstract：:Vaccination directly protects vaccinated individuals, but it also has the potential for indirectly protecting the unvaccinated in a population (herd protection). Unintended negative consequences such as the re-manifestation of infection, mainly expressed as age shifts, result from vaccination programs as well. We disc...

journal_title：Human vaccines & immunotherapeutics

authors： Scarbrough Lefebvre CD,Terlinden A,Standaert B

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Vitamin D is an immunomodulating hormone, which has been associated with susceptibility to infectious diseases. METHODS:Serum vitamin D levels in 135 children ages 3-17 y were measured at baseline and hemagglutinin influenza antibody titers were measured pre- and 21 d post influenza vaccination with live at...

journal_title：Human vaccines & immunotherapeutics

authors： Lin CJ,Martin JM,Cole KS,Zimmerman RK,Susick M,Moehling KK,Levine MZ,Spencer S,Flannery B,Nowalk MP

更新日期：2017-07-03 00:00:00

abstract：INTRODUCTION:The aim of the present study is to review the economic burden of varicella disease and the benefit of universal varicella vaccination in different settings pending its implementation in all Italian regions. MATERIALS AND METHODS:Research was conducted using PubMed, Scopus and ISI databases. Score quality ...

journal_title：Human vaccines & immunotherapeutics

authors： Unim B,Saulle R,Boccalini S,Taddei C,Ceccherini V,Boccia A,Bonanni P,La Torre G

更新日期：2013-09-01 00:00:00

abstract：:Previously, we have shown that DNA prime-protein boost is effective in eliciting neutralizing antibodies (NAb) against randomly selected HIV-1 isolates. Given the genetic diversity of HIV-1 viruses and the unique predominant subtypes in different geographic regions, it is critical to test the DNA prime-protein boost a...

journal_title：Human vaccines & immunotherapeutics

authors： Zhang M,Zhang L,Zhang C,Hong K,Shao Y,Huang Z,Wang S,Lu S

更新日期：2012-11-01 00:00:00

abstract：:Previously we showed that 65-kDa Mycobacterium leprae heat shock protein (Hsp65) is a target for the development of a tuberculosis vaccine. Here we evaluated peripheral blood mononuclear cells (PBMC) from healthy individuals or tuberculosis patients stimulated with two forms of Hsp65 antigen, recombinant DNA that enco...

journal_title：Human vaccines & immunotherapeutics

authors： Wowk PF,Franco LH,Fonseca DMD,Paula MO,Vianna ÉDSO,Wendling AP,Augusto VM,Elói-Santos SM,Teixeira-Carvalho A,Silva FDC,Vinhas SA,Martins-Filho OA,Palaci M,Silva CL,Bonato VLD

更新日期：2017-05-04 00:00:00