Independent Validation of a Self-Report Version of the IBD Disability Index (IBDDI) in a Population-Based Cohort of IBD Patients.

abstract：BACKGROUND:The women's health aspect of inflammatory bowel disease (IBD) is a newer area of study; childbearing issues have received little attention despite the fact that IBD affects women predominantly during their childbearing years. The aim of this study was to better understand patients' considerations about pregn...

journal_title：Inflammatory bowel diseases

authors： Marri SR,Ahn C,Buchman AL

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Crohn's disease (CD) is a chronic and invalidating inflammatory bowel disease of unknown etiology. The coordinated action of the cytochrome metabolizing subfamily CYP3A and the transport protein P-glycoprotein (P-gp) in the enterocyte results in a reduced bioavailability of drugs administered orally...

journal_title：Inflammatory bowel diseases

authors： Fakhoury M,Lecordier J,Medard Y,Peuchmaur M,Jacqz-Agrain E

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Inflammatory bowel disease (IBD) affects people during their prime reproductive years. The thiopurines (6-mercaptopurine and azathioprine), commonly used for induction and maintenance of remission, are U.S. Food and Drug Administration (FDA) pregnancy category D, raising concern for fetal risk. We performed ...

journal_title：Inflammatory bowel diseases

authors： Akbari M,Shah S,Velayos FS,Mahadevan U,Cheifetz AS

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Mucosal healing (MH) as a treatment target for ulcerative colitis is of growing interest because it is associated with improved clinical outcomes. However, the feasibility and probability of reaching MH in clinical practice is unknown. We therefore evaluated the feasibility of "treating to target" according ...

journal_title：Inflammatory bowel diseases

authors： Bouguen G,Levesque BG,Pola S,Evans E,Sandborn WJ

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Evidence supports the role of adherent invasive Escherichia coli (AIEC) in the pathogenesis of inflammatory bowel disease (IBD). However, little is known about the phylogenetic structure and origin of this group of bacteria. Multi-locus sequence typing (MLST), and fimH sequence analysis were performed to elu...

journal_title：Inflammatory bowel diseases

authors： Sepehri S,Kotlowski R,Bernstein CN,Krause DO

更新日期：2009-11-01 00:00:00

abstract：:: Primary nonresponse and primary nonremission are important limitations of tumor necrosis factor (TNF) antagonists, occurring in 10% to 40% and 50% to 80% of patients with inflammatory bowel disease, respectively. The magnitude of primary nonresponse differs between phase III clinical trials and cohort studies, indic...

journal_title：Inflammatory bowel diseases

authors： Papamichael K,Gils A,Rutgeerts P,Levesque BG,Vermeire S,Sandborn WJ,Vande Casteele N

更新日期：2015-01-01 00:00:00

abstract：:Clinical and epidemiological studies have revealed that the incidence of colorectal cancer associated with ulcerative colitis increases with long-term chronic inflammation. Careful endoscopic observation and histological studies to check for dysplasia in the colon are important in detecting neoplasia. Current surveill...

journal_title：Inflammatory bowel diseases

authors： Matsumoto T,Iwao Y,Igarashi M,Watanabe K,Otsuka K,Watanabe T,Iizuka B,Hida N,Sada M,Chiba T,Kudo SE,Oshitani N,Nagawa H,Ajioka Y,Hibi T

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:The unavailability of standardized parameters in bowel ultrasonography (US) commonly used in Crohn's disease (CD) and the shortage of skilled ultrasonographers are 2 limiting factors in the use of this imaging modality around the world. The aim of this study is to evaluate interobserver agreement among exper...

journal_title：Inflammatory bowel diseases

authors： Calabrese E,Kucharzik T,Maaser C,Maconi G,Strobel D,Wilson SR,Zorzi F,Novak KL,Bruining DH,Iacucci M,Watanabe M,Lolli E,Chiaramonte C,Hanauer SB,Panaccione R,Pallone F,Ghosh S,Monteleone G

更新日期：2018-08-16 00:00:00

abstract：:Citrullination is a posttranslational modification of proteins mediated by a specific family of enzymes called peptidylarginine deiminases (PAD). Dysregulation of these enzymes is involved in the etiology of various diseases, from cancer to autoimmune disorders. In inflammatory bowel disease (IBD), data for a role of ...

journal_title：Inflammatory bowel diseases

authors： Dragoni G,De Hertogh G,Vermeire S

更新日期：2021-01-01 00:00:00

abstract：Background:The differentiation between intestinal tuberculosis (ITB) and Crohn's disease (CD) is a challenge. The aim of this study was to investigate a predictive model for differential diagnosis between ITB and CD. Methods:A total of 268 patients who were suspected of having ITB or CD were prospectively recruited be...

journal_title：Inflammatory bowel diseases

authors： Wu X,Huang H,Hou H,Shen G,Yu J,Zhou Y,Bosco MJ,Mao L,Wang F,Sun Z

更新日期：2018-10-12 00:00:00

abstract：:Inflammatory bowel disease (IBD) is a chronic remitting disorder with increasing incidence worldwide. The intestinal epithelial barrier plays a major role in IBD, contributing to its pathogenesis, evolution, and perpetuation over time. Until recently, studies focused on exploring the role of the intestinal epithelium ...

journal_title：Inflammatory bowel diseases

authors： Dotti I,Salas A

更新日期：2018-11-29 00:00:00

abstract：BACKGROUND:Although infliximab is widely accepted as a therapeutic option for inflammatory bowel disease, its therapeutic efficacy for the treatment of intestinal Behçet's disease (BD) is unknown. We investigated the short-term and long-term response rates to infliximab in intestinal BD and predictive factors of sustai...

journal_title：Inflammatory bowel diseases

authors： Lee JH,Cheon JH,Jeon SW,Ye BD,Yang SK,Kim YH,Lee KM,Im JP,Kim JS,Lee CK,Kim HJ,Kim EY,Kim KO,Jang BI,Kim WH

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Inflammatory bowel disease (IBD) patients have a high incidence of wound and overall postoperative complications. A totally laparoscopic approach could potentially reduce these risks. We adopted totally laparoscopic total proctocolectomy (TL-TPC) using the perineal wound for extraction as the procedure of ch...

journal_title：Inflammatory bowel diseases

authors： Holder-Murray J,Zoccali M,Hurst RD,Umanskiy K,Rubin M,Fichera A

更新日期：2012-05-01 00:00:00

abstract：Background:Anastomotic recurrence is frequent in patients with Crohn's disease (CD) following ileocecal resection. The degree of endoscopic recurrence, quantified by the Rutgeerts score (RS), is correlated with the risk of clinical and surgical recurrence. Noninvasive modalities such as capsule endoscopy (CE), magnetic...

journal_title：Inflammatory bowel diseases

authors： Yung DE,Har-Noy O,Tham YS,Ben-Horin S,Eliakim R,Koulaouzidis A,Kopylov U

更新日期：2017-12-19 00:00:00

abstract：BACKGROUND:Clostridium difficile infection (CDI) is common in patients with inflammatory bowel disease (IBD), often leading to diagnostic confusion and delays in IBD therapy escalation. This study sought to assess outcomes after CDI in IBD patients exposed to new or escalated immunosuppressive therapy. METHODS:This mu...

journal_title：Inflammatory bowel diseases

authors： Lukin DJ,Lawlor G,Hudesman DP,Durbin L,Axelrad JE,Passi M,Cavaliere K,Coburn E,Loftus M,Jen H,Feathers A,Rosen MH,Malter LB,Swaminath A,IBD-ReMEdY Study (Research, Mentoring, Education New York).

更新日期：2019-03-14 00:00:00

abstract：:MicroRNAs (miRNAs) are single-stranded RNA molecules, which influence the translation of messenger RNA and hence protein synthesis. The altered expression of miRNAs in disease states in cancer and autoimmune diseases including inflammatory bowel disease is providing new insights into disease pathogenesis. This underst...

journal_title：Inflammatory bowel diseases

authors： Whiteoak SR,Felwick R,Sanchez-Elsner T,Fraser Cummings JR

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Increased strength of red blood cell (RBC) aggregates are present during the acute inflammatory response and contribute to erythrocyte aggregation and may lead to microvascular dysfunction. Inflammatory bowel diseases (IBDs) are characterized by damage to the bowel wall. This damage may be at least partially...

journal_title：Inflammatory bowel diseases

authors： Maharshak N,Arbel Y,Shapira I,Berliner S,Ben-Ami R,Yedgar S,Barshtein G,Dotan I

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:Mesalamine suppositories are first-line therapy in active ulcerative proctitis; the standard regime still recommends multiple doses per day. The primary objective of this study was to show the noninferiority of once-daily administration of a novel 1 g mesalamine suppository versus thrice-daily administration...

journal_title：Inflammatory bowel diseases

authors： Andus T,Kocjan A,Müser M,Baranovsky A,Mikhailova TL,Zvyagintseva TD,Dorofeyev AE,Lozynskyy YS,Cascorbi I,Stolte M,Vieth M,Dilger K,Mohrbacher R,Greinwald R,International Salofalk Suppository OD Study Group.

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Children with inflammatory bowel disease (IBD) undergo imaging using ionizing radiation and may be exposed to high cumulative radiation. We hypothesized that children with IBD have high exposure to radiation from medical imaging. METHODS:An Institutional Review Board (IRB)-approved retrospective chart revie...

journal_title：Inflammatory bowel diseases

authors： Sauer CG,Kugathasan S,Martin DR,Applegate KE

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Current therapy for inflammatory bowel disease (IBD) patients often involves agents that suppress the immune system, placing patients at an increased risk for developing infections, of which several are potentially vaccine preventable. Many IBD patients are not being vaccinated appropriately. The aims of thi...

journal_title：Inflammatory bowel diseases

authors： Wasan SK,Coukos JA,Farraye FA

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:We have previously demonstrated that inhibition of dipeptidyl peptidase (DP) activity partially attenuates dextran sulfate sodium (DSS) colitis in mice. The aim of this study was to further investigate the mechanisms of this protection. MATERIALS AND METHODS:Wildtype (WT) and DPIV(-/-) mice consumed 2% DSS ...

journal_title：Inflammatory bowel diseases

authors： Yazbeck R,Sulda ML,Howarth GS,Bleich A,Raber K,von Hörsten S,Holst JJ,Abbott CA

更新日期：2010-08-01 00:00:00

abstract：:Focal infection theory posits that periodontal pathobionts play a causal role in initiating or exacerbating diseases. Periodontal disease is a common inflammatory, multifactorial disease of the periodontal tissues. The main factor for inflammation is mature dental plaque with the presence of pathogens in the microbial...

journal_title：Inflammatory bowel diseases

authors： Barta Z

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND:Mutations in the nucleotide oligomerization domain-2 (NOD2) gene and positive antibodies to microbial antigens have been found to be associated with the Crohn's disease (CD) phenotype, fibrostenosis. The aim of this study was to confirm these relationships in a large cohort of CD patients and to determine th...

journal_title：Inflammatory bowel diseases

authors： Ippoliti A,Devlin S,Mei L,Yang H,Papadakis KA,Vasiliauskas EA,McGovern DP,Abreu MT,Melmed G,Shaye O,Enayati P,Chen G,Choi J,Taylor K,Landers CJ,Rotter JI,Targan SR

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:The immediate early response gene X-1 (IEX-1) is a stress-inducible gene involved in the regulation of cell growth, apoptosis and inflammation. METHODS:Acute colitis was induced by treatment of IEX-1 knockout (KO) and wild type (WT) control mice with dextran sulfate sodium (DSS), whereas chronic colitis was...

journal_title：Inflammatory bowel diseases

authors： Ustyugova IV,Zhi L,Wu MX

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Current surveillance guidelines for patients with long-standing ulcerative colitis (UC) recommend repeated colonoscopy with random biopsies, which is time-consuming, discomforting, and expensive. A less invasive strategy is to identify neoplasia by analyzing biomarkers from the more accessible rectum to pred...

journal_title：Inflammatory bowel diseases

authors： Bista RK,Brentnall TA,Bronner MP,Langmead CJ,Brand RE,Liu Y

更新日期：2011-12-01 00:00:00

abstract：Background:In Crohn's disease (CD) a small bowel study-in addition to colonoscopy-is considered necessary for diagnosis/staging. In this study we re-examined the role of capsule endoscopy (CE), colonoscopy, imaging tests [magnetic resonance enterography/computed tomographic enterography (MRE/CTE)], and inflammatory mar...

journal_title：Inflammatory bowel diseases

authors： Sorrentino D,Nguyen VQ

更新日期：2018-06-08 00:00:00

abstract：BACKGROUND:There has been a remarkable increase in the incidence of Crohn's disease (CD) among Arabs in recent years. We conducted this study to determine the clinical epidemiology of CD in Kuwait. METHODS:Sociodemographic and clinical information was collected for a continuous series of 206 Arab patients with CD and ...

journal_title：Inflammatory bowel diseases

authors： Siddique I,Alazmi W,Al-Ali J,Al-Fadli A,Alateeqi N,Memon A,Hasan F

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Many chronic illnesses are accompanied by impaired cognitive functioning. In people with Inflammatory Bowel Disease (IBD), there is some research to suggest a decrement in verbal IQ (VIQ), when compared to people with Irritable Bowel Syndrome (IBS) and healthy controls. Although this is an important finding,...

journal_title：Inflammatory bowel diseases

authors： Dancey CP,Attree EA,Stuart G,Wilson C,Sonnet A

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Vitamin D insufficiency has been suggested to be associated with high risk of Crohn's disease (CD). In France, where food fortification is limited, the major source of vitamin D is through sun exposure. The aim of this work was to analyze the relationship between residential sun exposure and the risk of inci...

journal_title：Inflammatory bowel diseases

authors： Jantchou P,Clavel-Chapelon F,Racine A,Kvaskoff M,Carbonnel F,Boutron-Ruault MC

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Our objectives were to assess the differences in perforating disease behavior, disease severity, and extraintestinal manifestations (EIM) in patients with Crohn's disease (CD) by race. MATERIALS AND METHODS:We identified outpatients with CD evaluated at the University of Maryland Gastroenterology Faculty Pr...

journal_title：Inflammatory bowel diseases

authors： Cross RK,Jung C,Wasan S,Joshi G,Sawyer R,Roghmann MC

更新日期：2006-03-01 00:00:00