Abstract:
PURPOSE:Endothelial dysfunction is a risk factor for osteonecrosis of femoral head (ONFH) and venous thromboembolism (VTE) [defined as deep venous thrombosis (DVT) or pulmonary embolism (PE)]. However, the risk of unprovoked VTE in non-traumatic ONFH patients remains unclear. METHODS:We investigated the relationship between ONFH and VTE using Taiwan National Health Insurance Research Database (NHIRD). Between 1997 and 2010, a total of 1514 non-traumatic ONFH patients were identified from 1,000,000 general populations after excluding initially concomitant diagnoses of DVT and PE, and subjects undergoing lower limb surgery within one year since enrollment. The comparison group (n = 15,140) without ONFH was set up by matching study cohort with age, gender, income and urbanization in a 1:10 ratio. Subjects diagnosed with VTE within one year after surgery were also excluded. RESULTS:The patients with non-traumatic ONFH had significantly higher frequency of unprovoked VTE, including DVT, than general population (1.19 vs. 0.5%, p < 0.0007), whereas the frequency of PE was similar between these two groups (p = 0.4922). The cumulative incidence of VTE and DVT was also remarkably higher in the ONFH than non-ONFH group (all p < 0.001). After adjusting for age, gender, medications and comorbidities with multivariate analysis, the ONFH patients had a 2.3-fold increase in risk of DVT compared with non-ONFH counterparts (95% CI 1.28 to 4.13, p = 0.0053). Apart from ONFH, age > 65 years and hypertension were also identified as risk factors for DVT occurrence. CONCLUSIONS:The incidence and risk of unprovoked VTE were significantly increased in the non-traumatic ONFH population.
journal_name
Int Orthopjournal_title
International orthopaedicsauthors
Sung PH,Chiang HJ,Yang YH,Chiang JY,Chen CJ,Yip HK,Lee MSdoi
10.1007/s00264-018-3866-2subject
Has Abstractpub_date
2018-07-01 00:00:00pages
1469-1478issue
7eissn
0341-2695issn
1432-5195pii
10.1007/s00264-018-3866-2journal_volume
42pub_type
杂志文章abstract:PURPOSE:The aim of the present study was to compare the daily activity and functionality in a patient cohort 12 months after total hip arthroplasty (THA) using a direct anterior approach with a healthy non-operated control population. METHODS:Sixty-four patients who underwent THA and 59 healthy individuals (control) w...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-017-3541-z
更新日期:2018-02-01 00:00:00
abstract::This experimental study was undertaken in mice to investigate the procedures for storage of allogenic cancellous bone. Cancellous grafts were were stored at -80 degrees C, -196 degrees C or freeze dried. Grafts were implanted into a defect in the recipient's femur and after one week the cellular kinetic activity was a...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00178753
更新日期:1990-01-01 00:00:00
abstract:INTRODUCTION:The most common reason for removal of well-fixed radial head prostheses is painful loosening. We hypothesised that short-stemmed prostheses, used for radial head arthroplasty, are not associated with an increased risk of implant loosening. METHODS:From 2002 to 2014, 65 patients were enrolled in a retrospe...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-017-3644-6
更新日期:2018-01-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章,评审
doi:10.1007/s00264-014-2281-6
更新日期:2014-06-01 00:00:00
abstract::We treated 25 patients with aggressive and malignant fibular tumours between April 1989 and May 2001. There were 11 osteosarcomas, seven Ewing's sarcoma and five chondrosarcomas. The tumours predominantly involved the upper one third; 16 were of Stage IIB. Neo-adjuvant and adjuvant chemotherapy were given to all patie...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-004-0566-x
更新日期:2004-10-01 00:00:00
abstract:PURPOSE:The failure of total hip systems caused by wear-particle-induced loosening has focused interest on factors potentially affecting wear rate. Remnants of the blasting material were reported on grit-blasted surfaces for cementless fixation. These particles are believed to cause third-body wear and implant loosenin...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-013-2135-7
更新日期:2014-04-01 00:00:00
abstract::The Mennen plate has been used for osteosynthesis of 5 femoral fractures, 4 of which were at the tip of a prosthesis stem. Union was achieved in 2 fractures, and loss of fixation of the plate in three. ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s002640050234
更新日期:1998-01-01 00:00:00
abstract::Extraskeletal osteosarcoma is very rare and is difficult to diagnose histologically. We report a case of a 63 year old women who had such a tumour in her thigh. ...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00182646
更新日期:1990-01-01 00:00:00
abstract:PURPOSE:The aim of the study was to investigate risk factors for metastasis at diagnosis. METHODS:We collected patients diagnosed with conventional chondrosarcoma between 1983 and 2014 from the Surveillance, Epidemiology, and End Results (SEER) database. Each patient was classified as having metastatic or localized di...
journal_title:International orthopaedics
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journal_title:International orthopaedics
pub_type: 杂志文章
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更新日期:2000-01-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-015-2705-y
更新日期:2015-06-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-013-2194-9
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abstract::Bone lengthening is a surgical method which requires meticulous technique, continuous attention, and satisfactory cooperation on the part of the patient. The absence of common criteria makes it difficult both to classify the complications which arise, and to compare them with those of other authors. We report the comp...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00180230
更新日期:1994-10-01 00:00:00
abstract:BACKGROUND:Surgical management of humeral fractures associated with radial nerve palsy remains controversial. Some advocate surgical treatment in emergency while others recommend nonoperative treatment. PURPOSE:The aim of the study was to assess nerve recovery in a series of patients treated with open reduction and in...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-015-2745-3
更新日期:2015-08-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章,评审
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abstract:BACKGROUND:Various types of dressing materials are available for wound care following hip and knee arthroplasty. However, it is unclear if one material is more beneficial than the others in terms of wound complications and fluid handling capacity. RESEARCH QUESTIONS:We performed a meta-analysis of randomized controlle...
journal_title:International orthopaedics
pub_type: 杂志文章,meta分析,评审
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更新日期:2017-07-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-006-0158-z
更新日期:2007-04-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-017-3558-3
更新日期:2018-02-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-013-1900-y
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abstract::Fractures around a femoral prosthesis have been treated with plating and additional cement, but this leads to further reduction of bone stock in the proximal femur. Since February 1992, we have dealt with this problem in 12 patients by revision using a long uncemented stem and distal interlocking combined with homolog...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s002640050112
更新日期:1997-01-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
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更新日期:2016-07-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
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更新日期:2014-03-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
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更新日期:2020-10-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-008-0714-9
更新日期:2009-12-01 00:00:00
abstract::Human immunodeficiency virus (HIV) infection has radically changed African orthopaedic practice within a decade. In Lusaka, a third of adults are infected, but most have no physical signs of the disease. Early experience showed that closed fractures healed normally, the risk of sepsis during osteosynthesis was increas...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s002640050074
更新日期:1996-01-01 00:00:00
abstract::First metatarsophalangeal joint replacement is an alternative surgical procedure to arthrodesis in the treatment of moderate-to-severe hallux rigidus. However, few studies have been published about functional outcome after joint reconstructive procedures for hallux rigidus. The purpose of this study was to assess clin...
journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-009-0935-6
更新日期:2010-10-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/BF00179704
更新日期:1991-01-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
doi:10.1007/s00264-009-0728-y
更新日期:2010-02-01 00:00:00
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journal_title:International orthopaedics
pub_type: 杂志文章
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更新日期:2007-08-01 00:00:00