Abstract：
:As a micro-engineered biomimetic system to replicate key functions of living organs, organ-on-a-chip (OC) technology provides a high-throughput model for investigating complex cell interactions with both high temporal and spatial resolutions in biological studies. Typically, microscopy and high-speed video cameras are used for data acquisition, which are expensive and bulky. Recently, compressed sensing (CS) has increasingly attracted attentions due to its extremely low-complexity structure and low sampling rate. However, there is no CS solution tailored for tempo-spatial information acquisition. In this paper, we propose tempo-spatial CS (TS-CS), a unified CS architecture for OC stream, which achieves significant cost reduction and truly combines sensing with compression along the temporal and spatial domains. We point out that TS-CS can consistently achieve better performance by exploiting tempo-spatial compressibility in OC data. To this end, we comprehensively evaluate the system performance by employing four different bases for CS. With comparison to the traditional way, we show that TS-CS always obtains better recovery result with a throughput bound and can achieve around throughput improvement under a reconstruction demand by applying discrete cosine transform matrix as the basis.
journal_name
IEEE J Biomed Health Informjournal_title
IEEE journal of biomedical and health informaticsauthors
Song C,Wang A,Lin F,Asmani M,Zhao R,Jin Z,Xiao J,Xu Wdoi
10.1109/JBHI.2017.2775559subject
Has Abstractpub_date
2018-03-01 00:00:00pages
325-334issue
2eissn
2168-2194issn
2168-2208journal_volume
22pub_type
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