Abstract:
:Patients undergoing a bone marrow stem cell transplant (BMT) face various risk factors. Analyzing data from past transplants could enhance the understanding of the factors influencing success. Records up to 120 measurements per transplant procedure from 1751 patients undergoing BMT were collected (Shariati Hospital). Collaborative filtering techniques allowed the processing of highly sparse records with 22.3% missing values. Ten-fold cross-validation was used to evaluate the performance of various classification algorithms trained on predicting the survival status. Modest accuracy levels were obtained in predicting the survival status (AUC = 0.69). More importantly, however, operations that had the highest chances of success were shown to be identifiable with high accuracy, e.g., 92% or 97% when identifying 74 or 31 recipients, respectively. Identifying the patients with the highest chances of survival has direct application in the prioritization of resources and in donor matching. For patients where high-confidence prediction is not achieved, assigning a probability to their survival odds has potential applications in probabilistic decision support systems and in combination with other sources of information.
journal_name
IEEE J Biomed Health Informjournal_title
IEEE journal of biomedical and health informaticsauthors
Taati B,Snoek J,Aleman D,Ghavamzadeh Adoi
10.1109/JBHI.2013.2274733subject
Has Abstractpub_date
2014-01-01 00:00:00pages
21-7issue
1eissn
2168-2194issn
2168-2208journal_volume
18pub_type
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