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Synchronization and Registration of Cine Magnetic Resonance and Dynamic Computed Tomography Images of the Heart.

Abstract：

:The synchronization and registration of dynamic computed tomography (CT) and magnetic resonance images (MRI) of the heart is required to perform a combined analysis of their complementary information. We propose a novel method that synchronizes and registers intrapatient dynamic CT and cine-MRI short axis view (SAX). For the synchronization step, a normalized cross-correlation curve is computed from each image sequence to describe the global cardiac dynamics. The time axes of these curves are then warped using an adapted dynamic time warping (DTW) procedure. The adaptation constrains the time deformation to obtain a coherent warping function. The registration step then computes the rigid transformation that maximizes the multiimage normalized mutual information of DTW-synchronized images. The DTW synchronization and the multiimage registration were evaluated using dynamic CT and cine-SAX acquisitions from nine patients undergoing cardiac resynchronization therapy. The distance between the end-systolic phases after DTW was used to evaluate the synchronization. Mean errors, expressed as a percentage of the RR-intervals, were 3.9% and 3.7% after adapted DTW synchronization against 10.8% and 11.3% after linear synchronization, for dynamic CT and cine-SAX, respectively. This suggests that the adapted DTW synchronization leads to a coherent warping of cardiac dynamics. The multiimage registration was evaluated using fiducial points. Compared to a monoimage and a two-image registration, the multiimage registration of DTW-synchronized images obtained the lowest mean fiducial error showing that the use of dynamic voxel intensity information improves the registration.

journal_name

IEEE J Biomed Health Inform

journal_title

IEEE journal of biomedical and health informatics

authors

Betancur J,Simon A,Langella B,Leclercq C,Hernandez A,Garreau M

doi

10.1109/JBHI.2015.2453639

subject

Has Abstract

pub_date

2016-09-01 00:00:00

pages

1369-76

issue

5

eissn

2168-2194

issn

2168-2208

journal_volume

20

pub_type

杂志文章

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