Abstract：
:Laryngopharyngeal Reflux (LPR) should be considered as part of extraesophageal reflux (EER). This reflux involves respiratory structures other than, or in addition to, the oesophagus. A new medical device for the treatment of gastric reflux, including LPR, has been launched in Italy: Marial®. Therefore, the aim of the present survey was to analyse the prescriptive behaviour both considering the past or current treatments and clinical features during a specialist routine visit. The current survey was conducted in 86 Otorhinolaryngological centers, distributed in all of Italy. Globally, 4.418 subjects [47% males and 53% females, 50.1 (14.5) years-of-age] were visited. The visits included laryngoscopy, Reflux Finding Score (RFS) and Reflux Symptom Index (RSI) questionnaires. The total RSI median score was 15 (12-19) and the total median RFS value was 10 (8-12). Interestingly, a significant change in the new drug prescription was observed (p<0.0001): over two-third of patients (67%) received Marial® as monotherapy, whereas PPI plus add-on were prescribed to almost one-third of the patients. PPI alone was prescribed in less than 1%. In conclusion, LPR is a common disorder characterized by typical signs and symptoms; LPR patients may be correctly identified and scored by evidence-based criteria. In addition, the present survey reported that LPR treatment has been considerably changed by the introduction of a new medical device.
journal_name
J Biol Regul Homeost Agentsjournal_title
Journal of biological regulators and homeostatic agentsauthors
Gelardi M,Silvestri M,Ciprandi G,The Relief Study Group: F. Aielli, P. Alessandrini, G. Allosso, S. Angelillo, A. Anni, G. Antoniacomi, S.E. Aragona, A. Armone Caruso, F. Asprea, R. Azzaro, G. Balata, C. Bellini, D. Benedetto, R. Bernardi, M. Buccsubject
Has Abstractpub_date
2018-01-01 00:00:00pages
9-19issue
1 Suppl. 2eissn
0393-974Xissn
1724-6083journal_volume
32pub_type
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journal_title：Journal of biological regulators and homeostatic agents
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