Orthodontic forces modulate insulin-like growth factor binding protein-5 changes in gingival crevicular fluid.

Abstract:

:Orthodontic tooth movement results from the response of the periodontal tissue to orthodontic force, which leads to modeling and remodeling of the surrounding alveolar bone. The response is considered to occur through the activation of specific signaling pathways, many of which are known, all acting to ultimately result in tooth movement. Much is known about the actions of these two cells, and the signaling pathways that affect them, both in bone and orthodontic literature, however, to date, little work has been carried out to examine the effect of the insulin-like growth factor binding proteins (IGFBP) in orthodontics. Therefore, we investigated the presence of IGFBP-5 in the gingival crevicular fluid (GCF) of 6 healthy subjects, and assessed the effects of orthodontic treatment on the levels and molecular state of this protein.

authors

Ballini A,Santacroce L,Cantore S,Saini R,Mastrangelo F,Desiate A,Scacco S

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

1235-1240

issue

4

eissn

0393-974X

issn

1724-6083

pii

42

journal_volume

30

pub_type

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