Effective treatment of narcolepsy-like symptoms with high-frequency repetitive transcranial magnetic stimulation: A case report.

Abstract:

RATIONALE:Narcolepsy is a rare sleep disorder with disrupted sleep-architecture. Clinical management of narcolepsy lies dominantly on symptom-driven pharmacotherapy. The treatment role of repetitive transcranial magnetic stimulation (rTMS) for narcolepsy remains unexplored. PATIENT CONCERNS:In this paper, we present a case of a 14-year-old young girl with excessive daytime sleepiness (EDS), cataplexy and hypnagogic hallucinations. DIAGNOSES:After excluding other possible medical conditions, this patient was primarily diagnosed with narcolepsy. INTERVENTIONS:The patient received 25 sessions of high-frequency rTMS over the left dorsolateral prefrontal cortex (DLPFC). OUTCOMES:The symptoms of EDS and cataplexy significantly improved after rTMS treatment. Meanwhile, her score in the Epworth sleep scale (ESS) also remarkably decreased. LESSONS:This case indicates that rTMS may be selected as a safe and effective alternative strategy for treating narcolepsy-like symptoms. Well-designed researches are warranted in future investigations on this topic.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Lai JB,Han MM,Xu Y,Hu SH

doi

10.1097/MD.0000000000008645

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

e8645

issue

46

eissn

0025-7974

issn

1536-5964

pii

00005792-201711170-00054

journal_volume

96

pub_type

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