Comprehensive analysis of biomarkers for prostate cancer based on weighted gene co-expression network analysis.

abstract：:Alpha-fetoprotein (AFP) has not played a large role in the surveillance of hepatocellular carcinoma due to inadequate sensitivity and specificity for active chronic hepatitis or cirrhosis. The aim of this study was to evaluate the diagnostic accuracy of AFP in small hepatocellular carcinomas after hepatitis C virus er...

journal_title：Medicine

authors： Minami T,Tateishi R,Kondo M,Nakagomi R,Fujiwara N,Sato M,Uchino K,Enooku K,Nakagawa H,Asaoka Y,Kondo Y,Moriya K,Shiina S,Koike K

更新日期：2015-06-01 00:00:00

abstract：:Cell and animal experiments have found that in addition to being a retinol transporter, Stimulated by Retinoic Acid 6 (STRA6) also functions as a surface signaling receptor by which retinol regulates insulin responses. Several studies revealed that the STRA6 gene may contribute to the pathogenesis of type 2 diabetes m...

journal_title：Medicine

authors： Hu S,Yan J,You Y,Yang G,Zhou H,Li X,Liao X,Tan H

更新日期：2019-03-01 00:00:00

abstract：RATIONALE:Unilateral manifestation of lymphedema during everolimus therapy has been described only rarely, mostly in transplant recipients. PATIENT CONCERNS:We report the first case of a patient who developed unilateral abdominal lymphedema, during a short period of everolimus treatment for renal cancer. DIAGNOSIS:Th...

journal_title：Medicine

authors： Halamkova J,Kazda T,Adamkova-Krakorova D,Rybnickova S,Kiss I,Demlova R

更新日期：2020-10-16 00:00:00

abstract：:The purpose of the study was to investigate the relationship between corneal deformation amplitude (DA), which is the amount of corneal displacement at highest degree of concavity measured by Corvis Scheimpflug Technology (ST), and various optic nerve head parameters in patients with primary open-angle glaucoma (POAG)...

journal_title：Medicine

authors： Jung Y,Park HL,Park CK

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Alzheimer disease (AD) is a common neurodegenerative disorder with distinct pathological features, with aging considered the greatest risk factor. We explored how aging contributes to increased AD risk, and determined concurrent and coordinate changes (including genetic and phenotypic modifications) commonly...

journal_title：Medicine

authors： Zheng JJ,Li WX,Liu JQ,Guo YC,Wang Q,Li GH,Dai SX,Huang JF

更新日期：2018-07-01 00:00:00

abstract：:Churg-Strauss Syndrome (CSS) complicated with cardiogenic shock is rare. Few case reports have described successful treatment of this rare disease. However, no one has reported on the application of mechanical life support with extracorporeal membrane oxygenation (ECMO) to treat this life-threatening disease.A 36-year...

journal_title：Medicine

authors： Cui N,Su L,Wang H,Long Y,Pang C,Yang F,Liu D

更新日期：2015-10-01 00:00:00

abstract：RATIONALE:Abdominal wall defects are common after tumor resection. PATIENT CONCERNS:We report an 83-year-old male patient with recurrent tumors in his abdomen, and who had an incision wound that could not be directly closed. Mesh was not suitable because the wound was infected. DIAGNOSES:Abdominal wall defect result ...

journal_title：Medicine

authors： Chen Q,Liu Q,Suo Y,Xie Q

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The digestive tract malignancies are a series of malignant tumor with high morbidity and mortality. Traditional Chinese medicine (TCM) combined with chemotherapy drugs interventions have been applied for the treatment of malignant tumors in Asian countries for dacades. This study aimed to assess the effectiv...

journal_title：Medicine

authors： Song Q,Zhang J,Wu Q,Li G,Leung EL

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Intrahepatic cholestasis of pregnancy (ICP) is a specific pregnancy-related disorder without standard medical therapies. Ursodeoxycholic acid (UDCA) is the most used medicine, but the efficacy and safety of UDCA remain uncertain. Several meta-analyses had been made to assess the effects of UDCA in ICP. Howev...

journal_title：Medicine

authors： Kong X,Kong Y,Zhang F,Wang T,Yan J

更新日期：2016-10-01 00:00:00

abstract：RATIONALE:Nonocclusive mesenteric ischemia (NOMI) is a life-threatening disorder; prompt diagnosis is vital. Surgical treatment is often required, but some cases can be treated conservatively. We herein report an extremely rare case wherein protein-losing enteropathy (PLE) developed after conservative treatment of NOMI...

journal_title：Medicine

authors： Shima T,Ozeki M,Kinoshita T,Honda K,Inoue H,Morita S

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Early and/or late onset in patients with brain injury (BI) is associated with a poorer prognosis, and phenytoin (PHT) is standard of care to prevent seizures. Levetiracetam (LEV), an alternative antiepileptic drug, is associated with less cognitive disruption. The purpose of this study was to evaluate the sa...

journal_title：Medicine

authors： Zhao L,Wu YP,Qi JL,Liu YQ,Zhang K,Li WL

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:According to the national census, China has gradually become an aging society; moreover, aging has become an irreversible worldwide trend in the twenty-first century. Aging can lead to decreased physical function, mobility, cardiopulmonary function and quality of life (QOL). The feasibility and benefits of c...

journal_title：Medicine

authors： Jia X,Jiang C,Tao J,Li Y,Zhou Y,Chen LD

更新日期：2018-08-01 00:00:00

abstract：:Repair of medial meniscus posterior root tear (MMPRT) is considered as an effective early intervention strategy for osteoarthritis. We aimed at evaluating whether or not single-photon emission computed tomography/computed tomography (SPECT/CT) could predict the treatment outcome.Eleven patients with MMPRT who underwen...

journal_title：Medicine

authors： Whi W,Park JY,Choi H,Paeng JC,Cheon GJ,Kang KW,Lee DS,Han HS

更新日期：2020-07-02 00:00:00

abstract：:This article compares the clinical characteristics and prognosis of young patients in different age groups with liver cancer (LC). In this retrospective study, we searched the Surveillance, Epidemiology, and End Results population-based database and identified 2641 patients who had been diagnosed with LC between 1988 ...

journal_title：Medicine

authors： Zhang W,Jiang R,Hou J,Sun B

更新日期：2015-03-01 00:00:00

abstract：:The long-term cardiovascular outcomes of a population-based cohort presenting to the emergency department (ED) with chest pain and classified with a clinical risk stratification algorithm are not well documented. The Olmsted County Chest Pain Study is a community-based study that included all consecutive patients pres...

journal_title：Medicine

authors： Farkouh ME,Aneja A,Reeder GS,Smars PA,Bansilal S,Lennon RJ,Wiste HJ,Razzouk L,Traverse K,Holmes DR Jr,Mathew V

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Aberrant activation of the immune system has been reported in asymptomatic hyperuricemia (HUA) patients. However, very few studies have elucidated the role of natural killer (NK) cells in this disease. METHODS:In this study, we evaluated the relationship between NK cells and HUA in 16 control subjects and 2...

journal_title：Medicine

authors： Gao L,Jiang Y,Wang Y,Qu X,Li L,Lou X,Wang Y,Guo H,Liu Y

更新日期：2018-12-01 00:00:00

abstract：:In this study, a constant pressure stimulus was applied on the 3 joints (first [p1], second [p2], and third [p3] joints) of 4 fingers (index, middle, ring, and little fingers), and the activation areas within Brodmann area 2 (BA 2) were compared for these different fingers and joints by using functional magnetic reson...

journal_title：Medicine

authors： Choi MH,Kim HS,Baek JH,Lee JC,Park SJ,Jeong UH,Gim SY,Kim SP,Lim DW,Chung SC

更新日期：2015-09-01 00:00:00

abstract：:The aim of this study was to evaluate the efficacy of dexmedetomidine in combination with sufentanil or butorphanol for postoperative analgesia in patients undergoing laparoscopic resection of a gastrointestinal tumor.This quasi-experimental trial was conducted in Nanchang, China, from January 2014 to December 2015. E...

journal_title：Medicine

authors： Zhang XK,Chen QH,Wang WX,Hu Q

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:To compare superb microvascular imaging with power Doppler imaging for evaluating joint lesion scores in rheumatoid arthritis based on high quality clinical cohort or case control studies. METHODS:We searched Medline (via PubMed), Web of Science, Cochrane Library, Embase, and Chinese Biomedical Literature D...

journal_title：Medicine

authors： Lin M,Wang C

更新日期：2020-09-11 00:00:00

abstract：:The Smith-Magenis syndrome (SMS) is a complex and rare congenital condition that is characterized by minor craniofacial anomalies, short stature, sleep disturbances, behavioral, and neurocognitive abnormalities, as well as variable multisystemic manifestations. Little is reported about spinal deformity associated with...

journal_title：Medicine

authors： Li Z,Shen J,Liang J,Sheng L

更新日期：2015-05-01 00:00:00

abstract：RATIONALE:Hemangioblastoma (HB) is a benign tumor that is typically located in the subtentorial region of the brain. HB that originates from dura mater is extremely rare. PATIENT CONCERNS:Herein, we reported a single case of a patient who presented with dizziness and headache lasting for 1 year that progressively aggr...

journal_title：Medicine

authors： Bian B,Zhang B,Zhou H,Tian J,Wang Z,Wang J

更新日期：2019-11-01 00:00:00

abstract：INTRODUCTION:Contracture of dacryocyst by an implanted lacrimal silicone tube is rare. This report describes a unique case of secondary dacryocystitis and the contracture of dacryocyst caused by a lacrimal silicone tube that was placed in the lacrimal system for 10 years. PATIENT CONCERNS:A 63-year-old female was diag...

journal_title：Medicine

authors： Li L,Lai Z,Huang W,Xu F,Wu Y

更新日期：2020-11-06 00:00:00

abstract：:Atrial remodeling plays a significant role during the progression of atrial fibrillation (AF). Left atrial wall thickness (LAT) is a subjective and easily acquirable indicator referring to structural remodeling. Therefore, we aimed to investigate the association between LAT and atrial remodeling substrate, and to expl...

journal_title：Medicine

authors： Zuo K,Li K,Liu M,Li J,Liu X,Liu X,Zhong J,Yang X

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Programmed death receptor-1 (PD-1)/programmed death ligand 1 (PD-L1) inhibitors have been demonstrated to improve the prognosis of patients with advanced non-small cell lung cancer (NSCLC) compared with chemotherapy. However, there were still some non-responders. Thus, how to effectively screen the responder...

journal_title：Medicine

authors： Huang Y,Shen A

更新日期：2020-08-21 00:00:00

abstract：:The process of determining the level of care and specific postacute care facility for stroke patients has not been adequately studied. The objective of this study was to better understand the factors that influence postacute care decisions by surveying stroke discharge planners. Requests were sent to discharge planner...

journal_title：Medicine

authors： Magdon-Ismail Z,Sicklick A,Hedeman R,Bettger JP,Stein J

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Healthcare workers (HCWs) were at the frontline during the battle against coronavirus. Understanding and managing their fears and anxieties may hold lessons for handling future outbreaks. However, the experiences and perceptions risk of HCWs from coronavirus still remains to be controversial. Thus, the objec...

journal_title：Medicine

authors： Chen P,Lei J,Chen F,Zhou B

更新日期：2020-05-01 00:00:00

abstract：:Human serotonin receptor 4 (HTR4) encodes a 5-HT4 receptor involved in learning, memory, depression, anxiety, and feeding behavior. The aim of this study was to investigate the association between the deoxyribonucleic acid (DNA) methylation of HTR4 promoter and autism spectrum disorder (ASD), a disease characterized b...

journal_title：Medicine

authors： Hu Z,Ying X,Huang L,Zhao Y,Zhou D,Liu J,Zhong J,Huang T,Zhang W,Cheng F,Duan S

更新日期：2020-01-01 00:00:00

abstract：:Dyslipidemia is one of the most important factors for coronary artery disease (CAD). The atherogenic index of plasma (AIP), a new comprehensive lipid index, might be a strong marker for predicting the risk of CAD.A hospital-based case-control study including 2936 CAD patients and 2451 controls was conducted in a Chine...

journal_title：Medicine

authors： Cai G,Shi G,Xue S,Lu W

更新日期：2017-09-01 00:00:00

abstract：:The present study provides a basic outline of the care and support that family caregivers offer to people affected by neuromuscular diseases.To determine the presence of burden in caregivers of people with neuromuscular diseases who use a wheelchair and to establish whether the presence of burden is influenced by cont...

journal_title：Medicine

authors： Pousada T,Groba B,Nieto-Riveiro L,Pazos A,Díez E,Pereira J

更新日期：2018-06-01 00:00:00

abstract：:Recent studies have investigated the most efficacious dose of intravenous tissue plasminogen activator (IV-tPA) for acute ischemic stroke (AIS) patients. There remains no definitive consensus concerning the superior efficacious IV-tPA dose (standard- vs. low-dose), prompting us to perform a meta-analysis comparing the...

journal_title：Medicine

authors： Liu MD,Ning WD,Wang RC,Chen W,Yang Y,Lin Y,Hu DH,Lau WB,Qu Y

更新日期：2015-12-01 00:00:00