Abstract:
:Alpha-fetoprotein (AFP) has not played a large role in the surveillance of hepatocellular carcinoma due to inadequate sensitivity and specificity for active chronic hepatitis or cirrhosis. The aim of this study was to evaluate the diagnostic accuracy of AFP in small hepatocellular carcinomas after hepatitis C virus eradication to determine the optimal cutoff value. We conducted a case-control study of 29 cases and 58 controls, matched for age, gender, and platelet counts. The AFP cutoff was 5 ng/mL in patients after hepatitis C virus eradication and 17 ng/mL in those without hepatitis C virus eradication. The areas under the receiver operating characteristic curve were 0.86 (95% confidence interval, 0.76-0.96) in patients after hepatitis C virus eradication and 0.83 (95% confidence interval, 0.74-0.91) in those without hepatitis C virus eradication. In patients after hepatitis C virus eradication, the sensitivity and specificity of AFP levels were 24.1% and 100%, respectively, using a cutoff value of 17 ng/mL. Using a lower cutoff value of 5 ng/mL, the sensitivity increased to 75.9%, although the specificity decreased to 89.0%. AFP is a specific tumor marker for the diagnosis of hepatocellular carcinoma after hepatitis C virus eradication when using the optimal cutoff value of 5 ng/mL.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Minami T,Tateishi R,Kondo M,Nakagomi R,Fujiwara N,Sato M,Uchino K,Enooku K,Nakagawa H,Asaoka Y,Kondo Y,Moriya K,Shiina S,Koike Kdoi
10.1097/MD.0000000000000901subject
Has Abstractpub_date
2015-06-01 00:00:00pages
e901issue
23eissn
0025-7974issn
1536-5964pii
00005792-201506020-00011journal_volume
94pub_type
杂志文章相关文献
MEDICINE文献大全abstract::This study is to determine accuracy of abdominal ultrasound and nuclear magnetic resonance imaging (MRI) for placenta accreta in the second and third trimester of pregnancy and to define the most relevant features of abdominal ultrasound and MRI for placenta accreta prediction.Between September 2012 and September 2018...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017908
更新日期:2020-01-01 00:00:00
abstract::The public sector scale-up of antiretroviral therapy (ART) in South Africa commenced in 2004. We aimed to describe the hospital-level disease burden and factors contributing to morbidity and mortality among hospitalized HIV-positive patients in the era of widespread ART availability. Between June 2012 and October 2013...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002269
更新日期:2015-12-01 00:00:00
abstract:RATIONALE:Choroidal detachment is a major postoperative complication of trabeculectomy. Postoperative choroidal detachment occurs with low intraocular pressure (IOP), and is naturally resolved by elevation of IOP. We report a case of chronic chorioretinal detachment (CRD) in the eye with uveitic glaucoma after trabecul...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018652
更新日期:2020-01-01 00:00:00
abstract:RATIONALE:Tuberculosis remains a serious menace to the health of people. Isolated hepatic tuberculosis is rare and pancreatic tuberculosis is extremely rare. The preoperative diagnosis of pancreatic tuberculosis remains a great challenge. PATIENT CONCERNS:A 58-year-old Asian woman was referred to our hospital for eval...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000012255
更新日期:2018-09-01 00:00:00
abstract::To evaluate the timing, feasibility, and necessity of early laparoscopic cholecystectomy (LC) in the management of patients with acute calculous cholecystitis complicated with hepatic dysfunction.The clinical data of 60 patients with acute calculous cholecystitis complicated with hepatic dysfunction treated from Janua...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020239
更新日期:2020-06-12 00:00:00
abstract:BACKGROUND:Anterior cruciate ligament rupture is a common motor system injury, and the most effective treatment is anterior cruciate ligament reconstruction (ACLR). Choosing the right graft is an important factor to ensure the success of the surgery. Current research shows that the clinical effect of autologous ligamen...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022832
更新日期:2020-10-23 00:00:00
abstract:BACKGROUND:Celiac disease is an autoimmune enteropathy characterized by an aberrant immune response to ingested gluten in genetically predisposed individuals. Studies have pointed to a rising prevalence of celiac disease in recent decades. Changes in diet and use of medication that may impact the gut microbiome have be...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000021488
更新日期:2020-08-28 00:00:00
abstract:BACKGROUND:The role of real-time elastography (RTE)-targeted biopsy in the detection and diagnosis of prostate cancer (PCa) remains controversial. METHODS:We searched Medline, Embase, and Cochrane Library from inception to July 31, 2017 and used the Quality Assessment of Diagnostic Accuracy Studies (QUADAS-2) tool to ...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000010220
更新日期:2018-03-01 00:00:00
abstract:INTRODUCTION:The odontogenic keratocyst (OKC), previously known as keratocystic odontogenic tumor has been the most disputable pathologies of the maxillofacial region. Patients with OKC are often asymptomatic but may present with pain, swelling, or discharge. Despite the aggressive nature, previous literature as early ...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000017987
更新日期:2019-12-01 00:00:00
abstract::Pheochromocytoma and paraganglioma (PPG) are rare and late-diagnosed catecholamine secreting tumors, which may be associated with unrecognized and/or severe cardiomyopathies. We performed a computer-assisted systematic search of the electronic Medline databases using the MESH terms "myocarditis," "myocardial infarctio...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000002198
更新日期:2015-12-01 00:00:00
abstract::Time resolved magnetic resonance angiography with interleaved stochastic trajectories (TWIST) allows for identification of tumor feeding arteries and arteriovenous shunt (AVS). We used TWIST to obtain number of feeding arteries (NFA) and detect AVS for 43 cases of pathology-confirmed soft tissue tumors. We compared no...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016346
更新日期:2019-07-01 00:00:00
abstract::Intussusception is common emergency condition in children. Pneumatic or hydrostatic reduction (HR) is considered the first-choice management strategy in cases lacking indications for surgical intervention. Generally, sedatives are not used in children undergoing interventional radiology procedures. Surgical management...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018956
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:The use of hysteroscopy for the diagnosis and treatment of uterine and endometrial abnormalities is often associated with postoperative pain. This randomized controlled trial aimed to assess the efficacy of preoperative intravenous (IV) lidocaine in reducing pain after hysteroscopy. METHODS:In total, 138 pa...
journal_title:Medicine
pub_type: 杂志文章,随机对照试验
doi:10.1097/MD.0000000000022751
更新日期:2020-10-16 00:00:00
abstract::The aim of this study was to elucidate the relationship between spinal cord injury (SCI) and the risk of peripheral arterial disease (PAD) in a cohort study with a large representative sample.The National Health Insurance Database was used to select patients who were diagnosed from 2000 to 2010. Patients with a histor...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001655
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:Alzheimer disease (AD) is a common neurodegenerative disorder with distinct pathological features, with aging considered the greatest risk factor. We explored how aging contributes to increased AD risk, and determined concurrent and coordinate changes (including genetic and phenotypic modifications) commonly...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000011343
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:To investigate the efficacy and safety of acupoint injection of Bacillus Calmette-Guerin polysaccharide nucleic acid (BCG-PSN) in the treatment of chronic urticaria (CU). METHODS:The following databases will be searched from their inception: Medline, Embase, Pubmed, Web of Science, Cochrane Central Register...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019924
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Effective treatment of low back pain (LBP) originating in the lumbar and sacroiliac joints is difficult to achieve. The objective of the current study was to compare the clinical effectiveness of radiofrequency (RF) neurotomy versus conservative nonsurgical approaches for the management of chronic lumbar and...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000016230
更新日期:2019-06-01 00:00:00
abstract::The purpose of the present study was to investigate the efficacy and safety of radiotherapy for patients with oligometastases from colorectal cancer (CRC).This was a retrospective cross-sectional study. Patients with liver and/or lung oligometastatic lesions from CRC treated with curative-intent radiotherapy in West C...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012601
更新日期:2018-10-01 00:00:00
abstract::This study aimed to evaluate the psychological distress and associated risk factors for distress among patients with gastric epithelial neoplasm undergoing endoscopic submucosal dissection (ESD).A total of 91 patients treated with ESD for gastric epithelial neoplasm between May 2015 and June 2016 were prospectively en...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000013912
更新日期:2018-12-01 00:00:00
abstract:RATIONALE:The sciatic nerve runs a predictable course combining L4-S3 nerve roots through the true pelvis and under the greater sciatic notch. There are reports of bony protuberances from the sacrum and ilium in cases of spinal dysraphism; however advanced imaging, treatment, or outcomes are not described. There are no...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009770
更新日期:2018-03-01 00:00:00
abstract::To investigate whether the control of morning blood pressure (MBP) reflects the control of blood pressure (BP) in other periods (daytime, nighttime and 24-hour) and to assess whether morning BP displays a closer association with subclinical target organ damage (TOD) than the BP measured in other periods.One thousand o...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019278
更新日期:2020-02-01 00:00:00
abstract::Subcutaneous tissue is a rare site of metastasis, accounting for only 1-2% of all lung neoplasms. Positron emission tomography (PET) using ¹⁸F-fluorodeoxyglucose (FDG) has been reported to increase the diagnostic accuracy of subcutaneous metastasis. A 58-year-old woman presented with complaints of dry coughing, in whi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000851
更新日期:2015-05-01 00:00:00
abstract::The World Health Organization and United Nations Children's Fund's Baby-Friendly Hospital Initiative is aimed at the global promotion, protection and support of breastfeeding. In this study, we compared breastfeeding-related information received, knowledge and behaviours among postpartum women in Baby-Friendly Hospita...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017737
更新日期:2019-11-01 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000002241.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/01.md.0000479433.86506.88
更新日期:2016-01-08 00:00:00
abstract::This study aimed to investigate the myocardial protective effect of liquid sodium phosphocreatine cardiac arrest in extracorporeal circulation surgery treating infants with atrial septal defects.Eighty-four infants with atrial septal defects who required extracorporeal circulation surgery treatment at our hospital fro...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020934
更新日期:2020-07-10 00:00:00
abstract::We aimed to obtain overall and regional estimates of hypertension prevalence, and to examine the pattern of this disease condition across different socio-demographic characteristics in low-and middle-income countries. We searched electronic databases from inception to August 2015. We included population-based studies ...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000001959
更新日期:2015-12-01 00:00:00
abstract::Disabled-2 (Dab2) is a clathrin and cargo-binding endocytic adaptor protein that plays a role in cellular trafficking of low-density lipoprotein receptor (LDLR). However, little is known about its involvement in coronary artery disease (CAD). Here, we aimed to investigate the association between Dab2 single-nucleotide...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020924
更新日期:2020-07-02 00:00:00
abstract:RATIONALE:Lymphatic embolization is a minimally invasive treatment option for managing chyle leakage after nodal dissection in the neck. After the procedure, the embolic material may cause foreign body granulomatous lymphadenitis and can be a diagnostic challenge for radiologists because of sonographic similarity to me...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012744
更新日期:2018-10-01 00:00:00
abstract::To evaluate the relationship between endometrial thickness during fresh in vitro fertilization (IVF) cycles and the clinical outcomes of subsequent frozen embryo transfer (FET) cycles.FET cycles using at least one morphological good-quality blastocyst conducted between 2012 and 2013 at a university-based reproductive ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009689
更新日期:2018-01-01 00:00:00
abstract:RATIONALE:Multiple primary malignancies can occur in the same organ or in multiple organs or systems. Likewise, they can occur simultaneously or successively. Based on the timing of the diagnosis, they are classified as multiple synchronous (i.e., concurrent) or metachronous (i.e., successive) primary malignancies. The...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011107
更新日期:2018-06-01 00:00:00