Eosinophilic esophagitis in an octogenarian: A case report and review of the literature.

Abstract:

INTRODUCTION:Eosinophilic esophagitis (EoE) is a chronic, immune/antigen-mediated disease characterized clinically by symptoms related to esophageal dysfunction and histologically by a marked eosinophilic infiltrate in the esophageal mucosa. What was once considered a rare disease has nowadays become one of the most frequent esophageal diseases in the Western countries, occupying a place just next to the gastroesophageal reflux disease. EoE etiology and pathogenesis remain largely unknown, although most studies consider that allergic and genetic factors play the most important role. METHODS:We report the case of EoE in an elderly male (octogenarian), giving a brief review of the current data related to epidemiology, pathogenesis, diagnosis, and treatment of the disease. RESULTS:Dysphagia to solid foods was the leading symptom, and endoscopic findings included white exudates, longitudinal furrows, and concentric mucosal rings, all suggestive for EoE. Diagnosis relied on histological findings in esophageal mucosal biopsies (>30 eosinophils per high power field).He was treated with topical steroids for 8 weeks, symptoms improved gradually and the patient remained in remission at the 8-month follow-up. CONCLUSION:This case emphasizes that EoE may occur in very old patients and gastroenterologists should have a high index of suspicion of this disorder in any elderly with dysphagia and endoscopic relevant features.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Trifan A,Stoica O,Chihaia CA,Danciu M,Stanciu C,Singeap AM

doi

10.1097/MD.0000000000005169

subject

Has Abstract

pub_date

2016-10-01 00:00:00

pages

e5169

issue

41

eissn

0025-7974

issn

1536-5964

pii

00005792-201610110-00054

journal_volume

95

pub_type

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