Recent advances in corneal collagen cross-linking.

Abstract:

:Corneal collagen cross-linking has become the preferred modality of treatment for corneal ectasia since its inception in late 1990s. Numerous studies have demonstrated the safety and efficacy of the conventional protocol. Our understanding of the cross-linking process is ever evolving, with its wide implications in the form of accelerated and pulsed protocols. Newer advancements in technology include various riboflavin formulations and the ability to deliver higher fluence protocols with customised irradiation patterns. A greater degree of customisation is likely the path forward, which will aim at achieving refractive improvements along with disease stability. The use of cross-linking for myopic correction is another avenue under exploration. Combination of half fluence cross-linking with refractive correction for high errors to prevent post LASIK regression is gaining interest. This review aims to highlight the various advancements in the cross-linking technology and its clinical applications.

journal_name

Indian J Ophthalmol

authors

Sachdev GS,Sachdev M

doi

10.4103/ijo.IJO_648_17

subject

Has Abstract

pub_date

2017-09-01 00:00:00

pages

787-796

issue

9

eissn

0301-4738

issn

1998-3689

pii

IndianJOphthalmol_2017_65_9_787_214653

journal_volume

65

pub_type

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