A novel cardiovascular death prediction model for Chinese individuals: A prospective cohort study of 381,963 study participants.

Abstract:

BACKGROUND AND AIMS:We aimed at developing a novel risk prediction model for death from cardiovascular disease (CVD) for Chinese individuals, based upon a large cohort from Taiwan. METHODS:This Chinese cohort came from Taiwan, with 381,963 individuals free from CVD, recruited from a private health surveillance program. With a median follow-up of 8.8 years, 1894 CVD deaths out of a total of 10,829 deaths were identified by linking cohort ID with the National Death File. RESULTS:A novel CVD death risk prediction model for Chinese individuals was established from this cohort. An increase in the resting heart rate was the statistically independent predictor in this model. The discriminatory accuracy was measured by generating the receiver operating characteristic (ROC) curve, and the area under the ROC curve was 0.913 (95% CI = 0.907 to 0.920). CONCLUSIONS:A novel cardiovascular death prediction model with high predictability for Chinese individuals was demonstrated in the present study.

journal_name

Atherosclerosis

journal_title

Atherosclerosis

authors

Hu WS,Lee JH,Tsai MK,Wen CP

doi

10.1016/j.atherosclerosis.2017.07.016

subject

Has Abstract

pub_date

2017-09-01 00:00:00

pages

19-28

eissn

0021-9150

issn

1879-1484

pii

S0021-9150(17)31191-7

journal_volume

264

pub_type

杂志文章
  • MicroRNA-27a/b regulates cellular cholesterol efflux, influx and esterification/hydrolysis in THP-1 macrophages.

    abstract:RATIONALE:Macrophage cholesterol homeostasis maintenance is the result of a balance between influx, endogenous synthesis, esterification/hydrolysis and efflux. Excessive accumulation of cholesterol leads to foam cell formation, which is the major pathology of atherosclerosis. Previous studies have shown that miR-27 (mi...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2014.02.008

    authors: Zhang M,Wu JF,Chen WJ,Tang SL,Mo ZC,Tang YY,Li Y,Wang JL,Liu XY,Peng J,Chen K,He PP,Lv YC,Ouyang XP,Yao F,Tang DP,Cayabyab FS,Zhang DW,Zheng XL,Tian GP,Tang CK

    更新日期:2014-05-01 00:00:00

  • Paraoxonase 1 (PON1) inhibits monocyte-to-macrophage differentiation.

    abstract:OBJECTIVE:To analyze paraoxonase 1 (PON1) effect on monocyte-to-macrophage differentiation. METHODS AND RESULTS:THP-1 monocytic cell-line and mouse peritoneal macrophages (MPM) were studied. Markers for monocytes differentiation included: morphological changes, CD11b and CD36 expression, and cellular oxidative stress....

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2011.06.054

    authors: Rosenblat M,Volkova N,Ward J,Aviram M

    更新日期:2011-11-01 00:00:00

  • Effect of KC-9432, a new hypolipidemic compound, on high density lipoprotein cholesterol in rats.

    abstract::KC-9432 (a new hypolipidemic compound, alpha-[p-(p-chlorobenzoyl) phenoxy-alpha-cyclohexyl acetic acid ethyl ester) was studied in rats for its effect on plasma lipid and lipoprotein levels. KC-9432 was particularly effective in hyperlipidemia in rats fed with a diet containing 2% cholesterol and 1% sodium cholate. Th...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(80)90097-0

    authors: Seri K,Sato R,Hamazaki Y,Yamamoto T,Ishiyama N

    更新日期:1980-09-01 00:00:00

  • Di-oleoyl phosphatidylcholine (PC-18:1) stimulates paraoxonase 1 (PON1) enzymatic and biological activities: in vitro and in vivo studies.

    abstract:OBJECTIVE:Paraoxonase 1 (PON1) is a high-density lipoprotein (HDL)-associated enzyme which possess anti-atherogenic properties. Our aim was to analyze the effect of HDL phospholipids on HDL-associated paraoxonase (PON1) catalytic and biological activities. METHODS AND RESULTS:In HDL isolated from di-oleoyl-phosphatidy...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2008.05.016

    authors: Efrat M,Rosenblat M,Mahmood S,Vaya J,Aviram M

    更新日期:2009-02-01 00:00:00

  • Effects of lipids and lipoproteins on thrombosis and rheology.

    abstract::Atherosclerotic plaque rupture and erosions precipitate thrombus formation and may lead to an acute ischemic syndrome. Lipids and lipoproteins modulate the expression and/or function of thrombotic, fibrinolytic and rheologic factors, and thereby influence hemostasis and potential tissue damage resulting from vascular ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,评审

    doi:10.1016/s0021-9150(98)00144-0

    authors: Rosenson RS,Lowe GD

    更新日期:1998-10-01 00:00:00

  • Research integrity and publication ethics.

    abstract::The basic principle for professional conduct of science in all countries and all disciplines is honesty towards oneself and towards others. Therefore it is utmost important that the scientific community prevents scientific misconduct by fostering research integrity. This commentary reports on the experience of a Germa...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2010.01.050

    authors: Beisiegel U

    更新日期:2010-10-01 00:00:00

  • Cartilage oligomeric matrix protein (COMP) in murine brachiocephalic and carotid atherosclerotic lesions.

    abstract:OBJECTIVE:To investigate the hypothesis that COMP can influence the morphology, stability and size of murine atherosclerotic lesions. METHODS:ApoE- and ApoE/COMP-knockout mice were fed a high-fat diet to develop atherosclerotic plaques at lesion sites of three different types; inflammatory and fibrous plaques induced ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2014.07.029

    authors: Bond AR,Hultgårdh-Nilsson A,Knutsson A,Jackson CL,Rauch U

    更新日期:2014-10-01 00:00:00

  • The protective effect of resveratrol on vascular aging by modulation of the renin-angiotensin system.

    abstract:BACKGROUND AND AIMS:This study evaluated the effects of resveratrol on arterial aging and the renin-angiotensin system (RAS) in mice and vascular smooth muscle cells (VSMCs). METHODS:Aging mice were divided into control and resveratrol groups. Histological changes, inflammation, oxidative stress, RAS components, and t...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2018.01.043

    authors: Kim EN,Kim MY,Lim JH,Kim Y,Shin SJ,Park CW,Kim YS,Chang YS,Yoon HE,Choi BS

    更新日期:2018-03-01 00:00:00

  • Molecular and clinical characterization of a series of patients with childhood-onset lysosomal acid lipase deficiency. Retrospective investigations, follow-up and detection of two novel LIPA pathogenic variants.

    abstract:BACKGROUND AND AIMS:Childhood/Adult-onset Lysosomal Acid Lipase Deficiency (LAL-D) is a recessive disorder due to loss of function variants of LAL, the enzyme which hydrolyses cholesteryl esters, derived from internalized apoB containing lipoproteins. The disease is characterized by multi-organ involvement including th...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.atherosclerosis.2017.08.021

    authors: Pisciotta L,Tozzi G,Travaglini L,Taurisano R,Lucchi T,Indolfi G,Papadia F,Di Rocco M,D'Antiga L,Crock P,Vora K,Nightingale S,Michelakakis H,Garoufi A,Lykopoulou L,Bertolini S,Calandra S

    更新日期:2017-10-01 00:00:00

  • Serial F-18-FDG PET/CT distinguishes inflamed from stable plaque phenotypes in shear-stress induced murine atherosclerosis.

    abstract:BACKGROUND:Detection of inflamed atherosclerotic plaques is of crucial importance. The carotid artery cuff-model in ApoE(-/-) mice results in shear-stress induced atherosclerosis with inflamed plaques upstream (US) and 'stable' plaques downstream (DS) of the cuff. We evaluated the potential of F-18-FDG PET/CT to differ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2014.03.008

    authors: Wenning C,Kloth C,Kuhlmann MT,Jacobs AH,Schober O,Hermann S,Schäfers MA

    更新日期:2014-06-01 00:00:00

  • The advantage of high-resolution MRI in evaluating basilar plaques: a comparison study with MRA.

    abstract:OBJECTIVE:Intracranial atherosclerosis (ICAS) is a major cause of ischemic stroke; however it is rather neglected. Vessel wall visualization by high resolution magnetic resonance imaging (HRMRI) might provide more accurate information. METHODS:A total of 219 consecutive patients with acute ischemic stroke underwent MR...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2012.07.037

    authors: Kim YS,Lim SH,Oh KW,Kim JY,Koh SH,Kim J,Heo SH,Chang DI,Lee YJ,Kim HY

    更新日期:2012-10-01 00:00:00

  • Cell proliferation in normal and atherosclerotic human aorta: proliferative splash in lipid-rich lesions.

    abstract::Local accumulation of cells (hypercellularity) in the intima of the arterial wall as a result of cell proliferation is recognized as one of the major manifestations of human atherosclerosis. In the present study we have used a monoclonal antibody against PCNA to identify the proliferative activity, in uninvolved intim...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/s0021-9150(98)00044-6

    authors: Orekhov AN,Andreeva ER,Mikhailova IA,Gordon D

    更新日期:1998-07-01 00:00:00

  • Carnitine palmitoyltransferase activity in mitochondrial fractions isolated from aortas of rabbits fed cholesterol-supplemented diets.

    abstract::beta-Oxidation of long-chain fatty acids increases many-fold in atherosclerotic aortas; this may be due to an increase in the activity of the mitochondrial enzyme hexadecanoyl-CoA: carnitine O-hexadecanoyltransferase EC 2.3.1.23 (trivial name: carnitine palmitoyltransferase, CPT). To investigate this possibility, an a...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(79)90102-3

    authors: Gillies PJ,Bell FP

    更新日期:1979-09-01 00:00:00

  • Adiponectin is associated with increased mortality and heart failure in patients with stable ischemic heart disease: data from the Heart and Soul Study.

    abstract:OBJECTIVE:Serum adiponectin protects against incident ischemic heart disease (IHD). However, in patients with existing IHD, higher adiponectin levels are paradoxically associated with worse outcomes. We investigated this paradox by evaluating the relationship between adiponectin and cardiovascular events in patients wi...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.atherosclerosis.2011.11.038

    authors: Beatty AL,Zhang MH,Ku IA,Na B,Schiller NB,Whooley MA

    更新日期:2012-02-01 00:00:00

  • Myocardial morphology in rabbits exposed to various gas-phase constituents of tobacco smoke--an ultrastructural study.

    abstract::Rabbits were continuously exposed to 200 ppm carbon monoxide. Using the same criteria as applied by earlier investigators for morphological myocardial damage, no histotoxic effect on myocardial morphology could be demonstrated when electron-microscopic investigations were performed blindly. Similarly, exposure to 0.5 ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(81)90037-x

    authors: Hugod C

    更新日期:1981-10-01 00:00:00

  • Fasting plasma glucose and subsequent cardiovascular disease among young adults: Analysis of a nationwide epidemiological database.

    abstract:BACKGROUND AND AIMS:Using a nationwide epidemiological database, we aimed to clarify the association of fasting plasma glucose (FPG) with subsequent cardiovascular disease (CVD) risk among young adults. METHODS AND RESULTS:Medical records of 1,180,062 young adults (20-49 years old) without a prior history of CVD and w...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2020.12.024

    authors: Kaneko H,Itoh H,Kiriyama H,Kamon T,Fujiu K,Morita K,Michihata N,Jo T,Takeda N,Morita H,Yasunaga H,Komuro I

    更新日期:2021-01-16 00:00:00

  • Arteriosclerosis in the African elephant: Part 2. Medial sclerosis.

    abstract:SUMMARY:A type of spontaneous arteriosclerosis, described as medial sclerosis and quite distinct from atherosclerosis, was found in the aortas, coronary arteries and aortic branch arteries of free-living elephants (Loxodonta africana) in Uganda and Kenya. The lesions took the form of calcified fibrotic plaques in the i...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(75)90093-3

    authors: McCullagh KG

    更新日期:1975-01-01 00:00:00

  • A brief review paper of the efficacy and safety of atorvastatin in early clinical trials.

    abstract::Preclinical and clinical data on atorvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, indicate that it has superior activity in treating a variety of dyslipidemic disorders characterized by elevations in low-density lipoprotein cholesterol (LDL-C) and/or triglycerides. Results for p...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,评审

    doi:10.1016/s0021-9150(97)06066-8

    authors: Bakker-Arkema RG,Best J,Fayyad R,Heinonen TM,Marais AD,Nawrocki JW,Black DM

    更新日期:1997-05-01 00:00:00

  • Impact of alcohol drinking on acetylcholine-induced coronary artery spasm in Korean populations.

    abstract:BACKGROUND AND AIMS:Generally, immoderate alcohol consumption is associated with variant angina and accepted as one of the risk factors for coronary artery spasm (CAS), but evidence is lacking in this regard. The aim of this study is to evaluate the impact of alcohol consumption and drinking pattern on CAS by acetylcho...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2017.11.032

    authors: Sohn SM,Choi BG,Choi SY,Byun JK,Mashaly A,Park Y,Jang WY,Kim W,Choi JY,Park EJ,Na JO,Choi CU,Lim HE,Kim EJ,Park CG,Seo HS,Oh DJ,Rha SW

    更新日期:2018-01-01 00:00:00

  • Lipids, risk factors and ischaemic heart disease.

    abstract::Over 200 risk factors for cardiovascular disease (CVD) have now been identified. Among these, the three most important are (1) abnormal lipids, including the fact that there are more than 15 types of cholesterol-containing lipoproteins and four different types of triglyceride-rich particles, some of which are very ath...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,评审

    doi:10.1016/0021-9150(96)05851-0

    authors: Castelli WP

    更新日期:1996-07-01 00:00:00

  • Vascular risk factors, vascular disease, lipids and lipid targets in patients with familial dysbetalipoproteinemia: a European cross-sectional study.

    abstract:BACKGROUND:Familial dysbetalipoproteinemia (FD), also known as type III hyperlipoproteinemia, is a genetic dyslipidemia characterized by elevated very low density lipoprotein (VLDL) and chylomicron remnant particles that confers increased risk of cardiovascular disease (CVD). The objective of this study was to evaluate...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.atherosclerosis.2015.02.046

    authors: Koopal C,Retterstøl K,Sjouke B,Hovingh GK,Ros E,de Graaf J,Dullaart RP,Bertolini S,Visseren FL

    更新日期:2015-05-01 00:00:00

  • Thoracic aortic atherosclerosis in patients with aortic regurgitation.

    abstract:OBJECTIVE:Hemodynamic forces are potential determinants of aortic atherosclerosis. Aortic regurgitation (AR) alters the flow pattern in the aorta. However, the association between AR and aortic atherosclerosis is not well known. METHODS:We assessed the presence, extent and distribution of atherosclerotic lesions in th...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2011.05.026

    authors: Shimoni S,Zilberman L,Edri O,Bar I,Goland S,Gendelman G,Swissa M,Livshitz S,Paz O,Ayzenberg O,George J

    更新日期:2011-09-01 00:00:00

  • Aortic response to relaxing agents in Watanabe heritable hyperlipidemic (WHHL) rabbits of different age.

    abstract::Serum and aortic tissue cholesterol levels in parallel with aortic relaxation to endothelium-dependent and independent drugs were determined in Watanabe heritable hyperlipidemic (WHHL) rabbits in comparison with New Zealand (N.Z.) normocholesterolemic rabbits, aged 4-14 months. Serum cholesterol was elevated (626 +/- ...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(91)90063-9

    authors: Chinellato A,Banchieri N,Pandolfo L,Ragazzi E,Froldi G,Norido F,Caparrotta L,Fassina G

    更新日期:1991-08-01 00:00:00

  • 360His polymorphism of the apolipoproteinA-IV gene and plasma lipid response to energy restricted diets in overweight subjects.

    abstract::Obesity is commonly associated with high rates of cardiovascular disease (CVD). Weight loss in obese subjects reduces risk factors for CVD but this response is not uniform. Genetic factors could be involved in this variability. The 360His polymorphism of apolipoproteinA-IV (apoA-IV) influences the lipid response to fa...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/s0021-9150(99)00367-6

    authors: Heilbronn LK,Noakes M,Morris AM,Kind KL,Clifton PM

    更新日期:2000-05-01 00:00:00

  • In vivo macrophage-specific RCT and antioxidant and antiinflammatory HDL activity measurements: New tools for predicting HDL atheroprotection.

    abstract::The beneficial therapeutic effects of raising HDL cholesterol are proving difficult to confirm in humans. The evaluation of antiatherogenic functions of HDL is an important area of research which includes the role of HDL in reverse cholesterol transport (RCT), especially macrophage-specific RCT, and its antioxidant an...

    journal_title:Atherosclerosis

    pub_type: 杂志文章,评审

    doi:10.1016/j.atherosclerosis.2008.12.044

    authors: Escolà-Gil JC,Rotllan N,Julve J,Blanco-Vaca F

    更新日期:2009-10-01 00:00:00

  • Benefits of salmon eating on traditional and novel vascular risk factors in young, non-obese healthy subjects.

    abstract:AIM:The present clinical study tested the hypothesis that oil-rich fish consumption improves CHD risk factors. METHODS:Forty-eight (16 men) non-obese, healthy adults aged 20-55, consumed 125 g/day of salmon for a 4-week period followed by a 4-week period with no-fish (41 completers). Subjects were instructed to mainta...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2006.06.018

    authors: Lara JJ,Economou M,Wallace AM,Rumley A,Lowe G,Slater C,Caslake M,Sattar N,Lean ME

    更新日期:2007-07-01 00:00:00

  • Hemodynamically-induced increase in soluble collagen in the anastomosed veins of experimental arteriovenous fistulae.

    abstract::External jugular veins that had been subjected to the hemodynamic stresses produced by experimental arteriovenous anastomosis developed 2% increased total protein contents and 17% increased collagen contents. When the stressed veins were homogenized and extracted with saline solutions, statistically significant increa...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(76)90004-6

    authors: Smith RA,Stehbens WE,Weber P

    更新日期:1976-05-01 00:00:00

  • Association of glucose metabolism, smoking and cardiovascular risk factors with incident peripheral arterial disease: the DESIR study.

    abstract:AIMS:We determined the 6-year incidence of peripheral arterial disease (PAD) in a French population and assessed the association of glucose metabolism, smoking, cardiovascular risk factors and physical activity with incident PAD. METHODS:Participants from the French Data from a Epidemiological Study on the Insulin Res...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2006.02.017

    authors: Tapp RJ,Balkau B,Shaw JE,Valensi P,Cailleau M,Eschwege E,DESIR Study Group.

    更新日期:2007-01-01 00:00:00

  • Effects of dietary sunflowerseed oil and marine oil on platelet membrane fluidity, arterial thrombosis, and platelet responses in rats.

    abstract::The relationships among platelet membrane fluidity, arterial thrombosis tendency, and platelet aggregation and prostanoid formation were investigated after feeding rats diets enriched in (n-6) or (n-3) polyunsaturated fatty acids. For at least 8 weeks, rats were fed a control diet containing 5 energy % (en%) sunflower...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/0021-9150(86)90101-2

    authors: Rand ML,Hennissen AA,Hornstra G

    更新日期:1986-12-01 00:00:00

  • Serum tissue inhibitor of metalloproteinases-1 and higher risk features of coronary plaque: a volumetric multivessel intravascular ultrasound study.

    abstract:AIMS:The purpose of this study was to determine the relationship between higher-risk features of coronary plaque and serum levels of matrix metalloproteinase (MMP) family enzymes in the stable angina patients. METHODS AND RESULTS:In 36 patients, 75 coronary lesions were assessed by intravascular ultrasound. For each o...

    journal_title:Atherosclerosis

    pub_type: 杂志文章

    doi:10.1016/j.atherosclerosis.2006.08.045

    authors: Kruk M,Kalińczuk L,Pregowski J,Przyłuski J,Janas J,Chmielak Z,Demkow M,Debski A,Ciszewski A,Otto B,Witkowski A,Ruzyłło W

    更新日期:2007-10-01 00:00:00