Abstract：
:Fungal prosthetic joint infection is a rare complication in total joint arthroplasty. There are no established guidelines for management of these infections. We present a case of a 53-year-old male with a hip joint prosthesis co-infected with Candida tropicalis and Staphylococcus haemolyticus. A two-stage exchange arthroplasty was performed. The patient underwent implant removal, debridement, irrigation with saline solution and application of cement spacer impregnated with vancomycin followed by aggressive antimicrobial treatment in first stage. Complete eradication of infection was demonstrated by negative culture of sonicated cement spacer fluid and negative 16S rRNA and 18S rRNA gene PCR of sonicate fluid, synovial fluid and periprosthetic tissue samples. He underwent second-stage revision hip arthroplasty after 9 months of the first stage. At the latest follow-up, there was no evidence of recurrence of infection. This case illustrates the utility of sonication of biomaterials and molecular techniques for microbiological confirmation of absence of infection in staged surgeries which is required for a successful outcome.
journal_name
Mycopathologiajournal_title
Mycopathologiaauthors
Sebastian S,Malhotra R,Pande A,Gautam D,Xess I,Dhawan Bdoi
10.1007/s11046-017-0177-xsubject
Has Abstractpub_date
2018-06-01 00:00:00pages
579-584issue
3eissn
0301-486Xissn
1573-0832pii
10.1007/s11046-017-0177-xjournal_volume
183pub_type
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