The effect of platelet-rich plasma on reducing blood loss after total knee arthroplasty: A systematic review and meta-analysis.

Abstract:

BACKGROUND:Efficacy and safety of platelet-rich plasma (PRP) compared with control for preventing postoperative bleeding after total knee arthroplasty (TKA) is controversial. We performed a meta-analysis of randomized controlled trials (RCTs) to determine whether PRP might reduce blood loss and improve function following TKA. METHODS:PubMed, Medline, Embase, Web of Science, and the Cochrane Library were searched to identify RCTs comparing PRP with control for patients undergoing unilateral TKA. The mean difference (MD) of total blood loss, hemoglobin (Hb) level, Hb drop, drain volume, range of motion (ROM), Western Ontario and McMaster Osteoarthritis Index (WOMAC) scores, length of hospital stay (LOS), and odds ratios of transfusion rate and postoperative complications in the PRP and control groups were pooled throughout the study. Relevant data were meta-analyzed using RevMan v5.3. RESULTS:Six RCTs involving 529 patients were included (208 PRP vs. 321 controls). The application of PRP in TKA had a significantly less calculated total blood loss (MD = -98.11; 95% confidence interval [CI]: -153.63 to -42.59, P = .0005) and lower Hb drop (MD = -0.34; 95% CI: -0.59 to -0.09, P = .008) than the control in the early postoperative period while decreasing the LOS (MD = -2.12; 95% CI: -3.47 to -0.76, P = .002). No significant differences were seen in drain volume, Hb level, transfusion rate, ROM, WOMAC scores, and complications between the 2 groups (P > .05). CONCLUSIONS:Our meta-analysis suggests that PRP appears to be effective in reducing postoperative blood loss and lowering Hb drop without increasing the risks of postoperative complications after TKA. However, owing to the variation of included studies, no firm conclusions can be drawn.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Ma J,Sun J,Guo W,Li Z,Wang B,Wang W

doi

10.1097/MD.0000000000007262

subject

Has Abstract

pub_date

2017-06-01 00:00:00

pages

e7262

issue

26

eissn

0025-7974

issn

1536-5964

pii

00005792-201706300-00028

journal_volume

96

pub_type

杂志文章,meta分析,评审

相关文献

MEDICINE文献大全
  • Risk of secondary cancers in women with breast cancer and the influence of radiotherapy: A national cohort study in Taiwan.

    abstract::Breast cancer is the most common cancer in women worldwide; thus, the prolongation of survival, and the incidence and risk factors, including radiotherapy, for developing secondary malignancies are important. We compared the incidence of secondary and new primary cancers in women with breast cancer (CA) and well-match...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005556

    authors: Lin CY,Chen SH,Huang CC,Weng SF,Lee ST,Guo HR,Kuo SC,Su SB

    更新日期:2016-12-01 00:00:00

  • Long-term outcomes of surgery alone versus surgery following preoperative chemoradiotherapy for early T3 rectal cancer: A propensity score analysis.

    abstract::Recently, a few studies have raised the question of whether preoperative chemoradiotherapy (PCRT) is essential for all T3 rectal cancers. This case-matched study aimed to compare the long-term outcomes of surgery alone with those of PCRT + surgery for magnetic resonance imaging (MRI)-assessed T3ab (extramural depth of...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000006362

    authors: Cho SH,Choi GS,Kim GC,Seo AN,Kim HJ,Kim WH,Shin KM,Lee SM,Ryeom H,Kim SH

    更新日期:2017-03-01 00:00:00

  • Efficacy of percutaneous vertebroplasty treatment of spinal tumors: A meta-analysis.

    abstract:OBJECTIVE:To evaluate the function of percutaneous vertebroplasty (PVP) treatment to pain relief and life quality for patients with spinal tumors. METHODS:Articles about the researches on the treatment of spinal tumors by PVP in PubMed, Embase, and the Chinese Biomedical Literature database from January 1, 2015 to Dec...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000009575

    authors: Qi L,Li C,Wang N,Lian H,Lian M,He B,Bao G

    更新日期:2018-01-01 00:00:00

  • Erratum: Risk of sudden sensorineural hearing loss in stroke patients: A 5-year nationwide investigation of 44,460 patients: Erratum.

    abstract::[This corrects the article DOI: 10.1097/MD.0000000000004841.]. ...

    journal_title:Medicine

    pub_type: 已发布勘误

    doi:10.1097/MD.0000000000006217

    authors:

    更新日期:2017-02-17 00:00:00

  • Dose-Effectiveness Relationships Determining the Efficacy of Ibandronate for Management of Osteoporosis: A Meta-Analysis.

    abstract::The purpose of this study was to perform a meta-analysis on the efficacy of ibandronate by evaluating the effect sizes of different dosing regimens.Major electronic databases were searched from 1985 to February 2015. A random effects meta-analysis was performed in STATA.Data from 34 studies (13,639 patients) were incl...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000001007

    authors: Hou Y,Gu K,Xu C,Ding H,Liu C,Tuoheti Y

    更新日期:2015-07-01 00:00:00

  • High-energy focused extracorporeal shock wave therapy for bone marrow edema syndrome of the hip: A retrospective study.

    abstract::The objective of this retrospective study was to evaluate the efficacy of high-energy focused extracorporeal shock wave therapy (HF-ESWT) on painful bone marrow edema syndrome (BMES) of the hip and shorten the natural course of disease.Thirty-four consecutive patients with BMES of the hip were treated with HF-ESWT in ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000019747

    authors: Zhang L,Cui Y,Liang D,Guan J,Liu Y,Chen X

    更新日期:2020-04-01 00:00:00

  • Takotsubo syndrome triggered by change in position in a patient with thoracic vertebral fracture: A case report.

    abstract:RATIONALE:Takotsubo syndrome (TTS) is characterized by recovery of wall motion abnormalities and acute left ventricular dysfunction, which are often caused by acute physical or emotional stressors. It is rarely reported that TTS can be precipitated by change in position in the patient in the operating room. We report a...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000024088

    authors: Zhang Z,Kong H,Zhang SY,Guan TT

    更新日期:2021-01-15 00:00:00

  • D-lactic acidosis. A review of clinical presentation, biochemical features, and pathophysiologic mechanisms.

    abstract::This report describes a case of d-lactic acidosis observed by the authors and then reviews all case reports of d-lactic acidosis in the literature in order to define its clinical and biochemical features and pathogenetic mechanisms. The report also reviews the literature on metabolism of d-lactic acid in humans. The c...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/00005792-199803000-00001

    authors: Uribarri J,Oh MS,Carroll HJ

    更新日期:1998-03-01 00:00:00

  • Comparison of the effectiveness of autologous grafts for anterior cruciate ligament reconstruction: A protocol for an overview of systematic review and network meta-analysis.

    abstract:BACKGROUND:Anterior cruciate ligament rupture is a common motor system injury, and the most effective treatment is anterior cruciate ligament reconstruction (ACLR). Choosing the right graft is an important factor to ensure the success of the surgery. Current research shows that the clinical effect of autologous ligamen...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000022832

    authors: Jin JX,Fang PZ,Hu ZW,Chen JL,Wang RR,Wang X

    更新日期:2020-10-23 00:00:00

  • A rare case report of a saddle pulmonary embolism presenting with high grade fevers, responsive to anticoagulation.

    abstract:RATIONALE:Pulmonary embolism can manifest by a myriad of clinical symptoms. High grade fever is a rare presentation of thromboembolic phenomenon. PATIENT CONCERNS:A middle aged woman presented with high grade fevers. DIAGNOSES:Patient remained febrile despite broad spectrum antibiotics. All cultures were negative. CT...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010002

    authors: Saad M,Shaikh DH,Adrish M

    更新日期:2018-03-01 00:00:00

  • Impressive long-term response with chemo-endocrine therapy in a premenopausal patient with metastatic breast cancer: A case report.

    abstract:RATIONALE:Patients with, or who develop, metastatic breast cancer have a 5-year relative survival of about 25%. Endocrine therapy clearly improves outcomes in patients with estrogen receptor-positive breast cancer. In the metastatic setting, the primary goal of treatment is to maintain long-term disease control with go...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000020396

    authors: Maltoni R,Palleschi M,Gallerani G,Bravaccini S,Cecconetto L,Melegari E,Altini M,Rocca A

    更新日期:2020-06-12 00:00:00

  • Clinical efficacy of oral immunoglobulin Y in infant rotavirus enteritis: Systematic review and meta-analysis.

    abstract:BACKGROUND:Rotavirus (RV) can cause vomiting and diarrhea in infants and children, and could be treated clinically with immunoglobulin Y (IgY), which is an immunoglobulin extracted from chicken yolk. There is no systematic evaluation of immunoglobulin in the treatment of rotavirus enteritis. Therefore, we systematicall...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000016100

    authors: Wang X,Song L,Tan W,Zhao W

    更新日期:2019-07-01 00:00:00

  • Capillary hemangioma arising from the lesser omentum in an adult: A case report.

    abstract:RATIONALE:Although capillary hemangiomas, common lesions involving the proliferation of small capillary vessels and a single layer of endothelial cells, can arise in any organ, they are rarely reported in the greater or lesser omentum. Here in, we report a case of capillary hemangioma arising from the lesser omentum in...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000018693

    authors: Nagano H,Goi T,Taguchi S,Tsubaki T,Tsuchiyama T,Uematsu H,Noriki S

    更新日期:2020-01-01 00:00:00

  • A case report of lupus erythematosus tumidus converted from discoid lupus erythematosus.

    abstract:RATIONALE:Lupus erythematosus tumidus (LET) is an uncommon type of cutaneous lupus erythematosus (CLE) that is rarely associated with other forms of lupus erythematosus. PATIENT CONCERNS:We report a 62-year-old Chinese man presented with recurrent erythematous facial plaques for 1 year and a low-grade fever for 1 week...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010375

    authors: Chen X,Wang S,Li L

    更新日期:2018-04-01 00:00:00

  • The effect of wide resection margin in patients with intrahepatic cholangiocarcinoma: A single-center experience.

    abstract:INTRODUCTION:Prognosis of intrahepatic cholangiocarcinoma (ICC) remained poor despite the multitude advancement of medical care. Resection margin status is one of the few modifiable factors that a surgeon could possibly manipulate to alter the disease outcome. However, the significance of margin status and margin width...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000004133

    authors: Ma KW,Cheung TT,She WH,Chok KSH,Chan ACY,Ng IOL,Chan SC,Lo CM

    更新日期:2016-07-01 00:00:00

  • Mild encephalopathy with a reversible splenial lesion mimicking transient ischemic attack: A case report.

    abstract:BACKGROUND:Reversible splenial lesion syndrome (RESLES) is a newly recognized syndrome, and a reversible progress associated with transiently reduced diffusion lesion in the splenium of the corpus callosum (SCC) is the typical pathological finding. The routine clinical symptoms include mildly altered states of consciou...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000005258

    authors: Dong K,Zhang Q,Ding J,Ren L,Zhang Z,Wu L,Feng W,Song H

    更新日期:2016-11-01 00:00:00

  • An ovarian Leydig cell tumor of ultrasound negative in a postmenopausal woman with hirsutism and hyperandrogenism: A case report.

    abstract:RATIONALE:The incidence of severe hyperandrogenism associated with masculinity in women is very low. While rare and difficult to diagnose, androgen secreting tumors should be suspected in women with hyperandrogenism and hirsutism, especially in the postmenopausal population. Herein we present one case of ovarian Leydig...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000010093

    authors: Chen M,Zhou W,Zhang Z,Zou Y,Li C

    更新日期:2018-03-01 00:00:00

  • Evaluation of the efficacy of Conbercept in the treatment of diabetic macular edema based on OCTA.

    abstract:BACKGROUND:Diabetic macular edema (DME) can cause severe vision impairments for patients with diabetes. Recently, Conbercept has shown efficacy on DME with 3-monthly loading dose injection and pro re nata (PRN, 3+PRN) thereafter in retrospectivetrials. Furthermore, there are some other approaches have been recommended ...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000021992

    authors: Ba T,Zhou L,Zhang H,Zhang X,Guo S,Li H,Tian H,Caihan Q,Bai G,Zhou J,Qi L,Zhang X,Zhang G

    更新日期:2020-08-28 00:00:00

  • Effectiveness of extracorporeal shock-wave therapy for frozen shoulder: A protocol for a systematic review of randomized controlled trial.

    abstract:BACKGROUND:This systematic review aims to explore the effectiveness and safety of extracorporeal shock-wave therapy (ESWT) for patients with frozen shoulder. METHODS:The sources of Cochrane Central Register of Controlled Trials, EMBASE, MEDLINE, Cumulative Index to Nursing and Allied Health Literature, Web of Science,...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000014506

    authors: Cao DZ,Wang CL,Qing Z,Liu LD

    更新日期:2019-02-01 00:00:00

  • A retrospective study of transcutaneous vagus nerve stimulation for poststroke epilepsy.

    abstract:BACKGROUND:This study assessed the effect transcutaneous vagus nerve stimulation (TVNS) for poststroke epilepsy (PSE). METHODS:Fifty-two patients with PSE were included in this study. Twenty-seven patients received TVNS, 30 minutes each session, once daily, twice weekly for a total of 4 weeks; and were assigned to the...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011625

    authors: Song GF,Wang HY,Wu CJ,Li X,Yang FY

    更新日期:2018-08-01 00:00:00

  • Diamond-shaped patch technique for right hepatic vein reconstruction in living-donor liver transplant: A simple method to prevent stenosis.

    abstract::Patency of the right hepatic vein (RHV) of the liver graft is essential for successful living-donor liver transplant (LDLT). We developed a simple technique for RHV reconstruction that does not require the use of cadaveric veins or additional time to prevent stenosis.Of 159 patients who underwent LDLT at our instituti...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000011815

    authors: Lee TB,Choi BH,Yang KH,Ryu JH,Park YM,Chu CW

    更新日期:2018-08-01 00:00:00

  • Cirrhosis and frailty assessment in elderly patients: A paradoxical result.

    abstract::The frailty represents a key determinant of elderly clinical assessment, especially because it allows the identification of risk factors potentially modifiable by clinical and therapeutic interventions. The frailty assessment in elderly patients usually is made by using of Fried criteria. However, to assess the frailt...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000018501

    authors: Federico A,Caprio GG,Dalise AM,Barbieri M,Dallio M,Loguercio C,Paolisso G,Rizzo MR

    更新日期:2020-01-01 00:00:00

  • Effect of mGluR7 on proliferation of human embryonic neural stem cells.

    abstract::This study is to investigate the effect of metabotropic glutamate receptor 7 (mGluR7) on the proliferation of human embryonic neural stem cells (NSCs) and its molecular mechanism.Human embryonic NSCs were isolated. The pCMV2-GV146-GFP-mGluR7 plasmid was transfected to over-express mGluR7 while mGluR7 siRNA was transfe...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000014683

    authors: Zhang J,Zhao J,Chen Y,Shi H,Huang X,Wang Y,Wang Y,Wei Y,Xue W,Han J

    更新日期:2019-03-01 00:00:00

  • Dietary fat intake and endometrial cancer risk: A dose response meta-analysis.

    abstract::Since body fatness is a convincing risk factor for endometrial cancer, dietary fat intake was speculated to be associated with endometrial cancer risk. However, epidemiological studies are inconclusive. We aimed to conduct a meta-analysis to assess the associations between dietary fat intake and endometrial cancer ris...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/MD.0000000000004121

    authors: Zhao J,Lyu C,Gao J,Du L,Shan B,Zhang H,Wang HY,Gao Y

    更新日期:2016-07-01 00:00:00

  • Familial Mediterranean fever: report of a large family, review of the literature, and discussion of the frequency of amyloidosis.

    abstract::Familial Mediterranean Fever is a rare disease which usually begins in childhood and occurs primarily among persons of Mediterranean ancestry. It is characterized by short, self-limited, febrile episodes that may occur alone or with inflammation of serosal surfaces. Some individuals may exhibit an erysipilas-like eryt...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Meyerhoff J

    更新日期:1980-01-01 00:00:00

  • Reevaluation of Neoadjuvant Chemotherapy for Esophageal Squamous Cell Carcinoma: A Meta-Analysis of Randomized Controlled Trials Over the Past 20 Years.

    abstract::The effect of neoadjuvant chemotherapy on the survival of patients with thoracic esophageal squamous cell carcinomas (ESCCs) remains controversial. The optimal management strategy for resectable ESCCs varies regionally based on local randomized controlled trials. A systematic review and meta-analysis was conducted to ...

    journal_title:Medicine

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/MD.0000000000001102

    authors: Zheng Y,Li Y,Liu X,Sun H,Wang Z,Zhang R

    更新日期:2015-07-01 00:00:00

  • Functional analysis of cell-free RNA using mid-trimester amniotic fluid supernatant in pregnancy with the fetal growth restriction.

    abstract::The prediction and monitoring of fetal growth restriction (FGR) fetuses has become with the use of ultrasound. However, these tools lack the fundamental evidence for the growth of fetus with FGR excluding pathogenic factors.Amniotic fluid samples were obtained from pregnant women for fetal karyotyping and genetic diag...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000009572

    authors: Cho HY,Cho Y,Shin YJ,Park J,Shim S,Jung Y,Shim S,Cha D

    更新日期:2018-01-01 00:00:00

  • Bacillus Calmette-Guérin (BCG) infection following intravesical BCG administration as adjunctive therapy for bladder cancer: incidence, risk factors, and outcome in a single-institution series and review of the literature.

    abstract::Bacillus Calmette-Guérin (BCG) is the most effective intravesical immunotherapy for superficial bladder cancer. Although generally well tolerated, BCG-related infectious complications may occur following instillation. Much of the current knowledge about this complication comes from single case reports, with heterogene...

    journal_title:Medicine

    pub_type: 杂志文章,评审

    doi:10.1097/MD.0000000000000119

    authors: Pérez-Jacoiste Asín MA,Fernández-Ruiz M,López-Medrano F,Lumbreras C,Tejido Á,San Juan R,Arrebola-Pajares A,Lizasoain M,Prieto S,Aguado JM

    更新日期:2014-10-01 00:00:00

  • Peritoneal epithelioid angiosarcoma: A case report.

    abstract:INTRODUCTION:Peritoneal angiosarcoma is an extremely rare sarcoma (0.01287% incidence per 100,000) with an aggressive course and a poor prognosis. In this case, the manifestation of peritoneal angiosarcoma was ascites, which caused difficulty in early diagnosis and the diagnosis of peritoneal angiosarcoma, was made onl...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000012054

    authors: Chen WJ,Wu IC,Wu CC,Yu FJ

    更新日期:2018-09-01 00:00:00

  • The pancreatic juice length in the stent tube as the predicting factor of clinical relevant postoperative pancreatic fistula after pancreaticoduodenectomy.

    abstract::Several risk factors for pancreatic fistula had been widely reported, but there was no research focusing on the exocrine output of remnant gland.During the study period of January 2015 to September 2016, 82 patients accepted pancreaticoduodenectomy (PD, end-to-end dunking pancreaticojejunostomy with internal stent tub...

    journal_title:Medicine

    pub_type: 杂志文章

    doi:10.1097/MD.0000000000008451

    authors: Wang H,Xiu D,Tao M

    更新日期:2017-11-01 00:00:00