HLA-DRB3*02:61Q , a novel HLA-DRB3 allele identified in a volunteer bone marrow donor.

abstract：:Adverse drug reactions (ADRs) are a common cause of hospital admissions (up to 19%), with the majority of cases due to off-target predictable drug effects (type A reactions). However, idiosyncratic drug-induced immune activated (type B) reactions contribute to a range of hypersensitivity reactions, with T-cell-mediate...

journal_title：HLA

authors： Mullan KA,Anderson A,Illing PT,Kwan P,Purcell AW,Mifsud NA

更新日期：2019-06-01 00:00:00

abstract：:One nucleotide substitution in codon 126 of HLA-C*01:02:01:01 results in a novel allele, HLA-C*01:02:43. ...

journal_title：HLA

authors： Yang KL,Li CC,Lin PY

更新日期：2020-11-01 00:00:00

abstract：:The killer cell lectin-like receptor B1 (KLRB1) gene encodes for CD161 expressed by different subsets of leukocytes involved in the development of acute liver transplant rejection. The single nucleotide polymorphism (SNP) 503T>C (rs1135816) in the KLRB1 gene represents a missense mutation modifying functional properti...

journal_title：HLA

authors： Thude H,Rother S,Sterneck M,Klempnauer J,Nashan B,Schwinzer R,Koch M

更新日期：2018-01-01 00:00:00

abstract：:Characterization of the novel HLA-C*15:228 and HLA-C*04:434 alleles in two Greek individuals of Cretan origin. ...

journal_title：HLA

authors： Batsali A,Latsoudis H,Vatsiou S,Stylianakis E,Papadaki HA

更新日期：2020-11-26 00:00:00

abstract：:Monitoring of donor-specific HLA antibodies (DSA) has become part of the clinical routine in kidney transplantation. This paper gives a brief overview on data from the Collaborative Transplant Study (CTS) and the Heidelberg Transplant Center on the clinical relevance of post-transplant DSA monitoring in patients under...

journal_title：HLA

authors： Süsal C,Aykut G,Morath C,Fichtner A,Unterrainer C,Scherer S,Tran TH,Mehrabi A,Zeier M,Tönshoff B

更新日期：2019-12-01 00:00:00

abstract：:One nucleotide substitution at residue 266 of HLA-DRB1*12:02:01:01 results in a new allele, HLA-DRB1*12:67. ...

journal_title：HLA

authors： Yang KL,Lin PY

更新日期：2017-11-01 00:00:00

abstract：:Two nucleotide replacements within HLA-B*40:01:01 result in the novel allele, HLA-B*40:01:45. ...

journal_title：HLA

authors： Yang KL,Lin PY

更新日期：2017-11-01 00:00:00

abstract：:HLA-DPA1*02:15 differs from HLA-DPA1*02:06 by one nucleotide substitution in codon 218 in exon 4. ...

journal_title：HLA

authors： Blouin L,Andreani M,Locatelli F,Guidicelli G,Visentin J

更新日期：2019-08-01 00:00:00

abstract：:The new HLA-B*39:01:01:04 allele differs from HLA-B*39:01:01 by a C → T substitution in intron 1. ...

journal_title：HLA

authors： Kwok J,Ho JC,Chan YS,Soormally A,Marsh SG

更新日期：2017-02-01 00:00:00

abstract：:The novel HLA-A*02:952 allele, first described in a potential bone marrow donor from Brazil. ...

journal_title：HLA

authors： Vianna R,Lopes G,Villela AP,Villas-Boas PR,Porto LC

更新日期：2021-01-28 00:00:00

abstract：:A*31:74: one nucleotide change resulting in a new motif ACG at codon 29 in HLA-A. ...

journal_title：HLA

authors： Li X,Zhuang Y,Zhao C

更新日期：2019-07-01 00:00:00

abstract：:One nucleotide replacement at codon 145 of HLA-B*15:01:01:01 results in a new allele, HLA-B*15:192. ...

journal_title：HLA

authors： Yang KL,Lin PY

更新日期：2018-06-01 00:00:00

abstract：:Genomic full-length sequence of HLA-A*11:172 was identified by a group-specific sequencing approach from China. ...

journal_title：HLA

authors： Xu YP,Yang H,Hong WX

更新日期：2018-10-01 00:00:00

abstract：:HLA-DRB3*02:142 differs from HLA-DRB3*02:02:01:02 by one nucleotide substitution in codon 98 in exon 3. ...

journal_title：HLA

authors： Cargou M,Andreani M,Galluccio T,Guidicelli G,Visentin J

更新日期：2020-06-01 00:00:00

abstract：:We have developed a protocol regarding the genomic characterization of the MICA gene by next generation sequencing (NGS). The amplicon includes the full length of the gene and is about 13 kb. A total of 156 samples were included in the study. Ninety-seven of these samples were previously characterized at MICA by legac...

journal_title：HLA

authors： Zou Y,Duke JL,Ferriola D,Luo Q,Wasserman J,Mosbruger TL,Luo W,Cai L,Zou K,Tairis N,Damianos G,Pagkrati I,Kukuruga D,Huang Y,Monos DS

更新日期：2020-10-01 00:00:00

abstract：:HLA-B*15:326 has one base substitution at position 176G>A in exon 2 compared with HLA-B*15:01:01:01. ...

journal_title：HLA

authors： Chen NY,Zhang W,He JJ,He J,Zhu FM

更新日期：2016-03-01 00:00:00

abstract：:The new HLA-B*15:583 and DRB1*11:279 alleles identified in Buryat and Russian individuals, respectively. ...

journal_title：HLA

authors： Loginova M,Makhova O,Kutyavina S,Paramonov I,Zarubin M

更新日期：2021-01-20 00:00:00

abstract：:HLA-E, a class I nonclassical HLA molecule, is expressed in all tissues and is involved in the regulation of both innate (by interaction with the CD94/NKG2 receptor expressed mainly in NK cells) and adaptive immunity (by interaction with T CD8+ cells), suggesting a possible role in the solid organ transplantation cont...

journal_title：HLA

authors： de Miranda BLM,Gelmini GF,Risti M,Hauer V,da Silva JS,Roxo VMMS,Bicalho MDG,Malheiros D

更新日期：2020-05-01 00:00:00

abstract：:Seven novel HLA-C alleles were detected using two next-generation sequencing technologies. ...

journal_title：HLA

authors： Senoussi O,Dard C,Buhler S,Bardy B,Masson D

更新日期：2020-07-01 00:00:00

abstract：:The new kidney allocation system in the United States has improved deceased donor transplant rates among candidates with high calculated panel reactive antibodies (CPRAs). Probability analysis predicts a very low transplant rate as the CPRA approaches 100%. This study sought to determine if the rate of deceased donor ...

journal_title：HLA

authors： Keith DS

更新日期：2020-01-01 00:00:00

abstract：:The novel allele HLA-C*16:123N has a single nucleotide difference with HLA-C*01:02:01:01 in exon 2. ...

journal_title：HLA

authors： Al Yafei Z,Alvares MS,Alkatheeri LM,Al Mahri A,ElGhazali G

更新日期：2019-06-01 00:00:00

abstract：:DRB1*15:175 differs from DRB1*15:01:01:02 by one nucleotide substitution at position 233 in exon 2. ...

journal_title：HLA

authors： Genebrier S,Elsermans V,Nivet C,Chérel M,Renac V

更新日期：2020-12-01 00:00:00

abstract：:One of the fundamental hallmarks of cancer is the incapacity of the immune system to eliminate malignancy. Cytotoxic T-lymphocyte antigen-4 (CTLA-4) and lymphocyte activation gene-3 (LAG-3) are considered major inhibitory immune checkpoints expressed on T cells. In this study, we investigated mRNA expression of CTLA-4...

journal_title：HLA

authors： Radwan SM,Elleboudy NS,Nabih NA,Kamal AM

更新日期：2020-07-01 00:00:00

abstract：:Nucleotide replacement at residue 12 of HLA-C*08:22 results in a novel allele, HLA-C*08:178. ...

journal_title：HLA

authors： Yang KL,Lin PY

更新日期：2019-06-01 00:00:00

abstract：:New HLA alleles found in the Finnish population: A*03:283N, A*68:167, C*03:327 and C*03:361. ...

journal_title：HLA

authors： Polvi A,Peräsaari J,Linjama T,Saarinen T,Koskela S,Voorter CEM,Jaatinen T

更新日期：2018-01-01 00:00:00

abstract：:HLA-A*11:141 has 1 nucleotide change from HLA-A*11:01:01 at position 470G>C. ...

journal_title：HLA

authors： Liu YY,Li GY,Tang ZH,Wu KL,Guo ZH

更新日期：2017-10-01 00:00:00

abstract：:One nucleotide substitution at nucleotide 594 of HLA-DRB1*14:54:01:01 results in a novel allele, HLA-DRB1*14:227. ...

journal_title：HLA

authors： Yang KL,Li CC,Lin PY

更新日期：2021-02-01 00:00:00

abstract：:HLA-B*40:338N differs from HLA-B*40:01:01 by a single nucleotide substitution at position 843C>A. ...

journal_title：HLA

authors： He J,Dong LN,Wang F,Wang W,Zhu FM

更新日期：2018-04-01 00:00:00

abstract：:Routine HLA typing in clinical practice encompassing solid organ and hematopoietic stem cells transplantation programs, disease association typing, volunteer marrow donor typing and population studies, provided a large dataset for studying HLA allele polymorphism in the Croatian population which led to the identificat...

journal_title：HLA

authors： Burek Kamenaric M,Maskalan M,Grubic Z,Stingl Jankovic K,Zunec R

更新日期：2020-07-01 00:00:00

abstract：:HLA-B*15:476 differs from HLA-B*15:01:01:01 by one nucleotide substitution at codon 299 in exon 5. ...

journal_title：HLA

authors： Ralazamahaleo M,Elsermans V,Top I,Guidicelli G,Visentin J

更新日期：2018-12-01 00:00:00