Detection of a novel HLA-DRB1*12 variant, HLA-DRB1*12:67, in a Taiwanese individual.

abstract：:Adverse drug reactions (ADR) can be broadly categorised as either on-target or off-target. On-target ADRs arise as a direct consequence of the pharmacological properties of the drug and are therefore predictable and dose-dependent. On-target ADRs comprise the majority (>80%) of ADRs, relate to the drug's interaction w...

journal_title：HLA

authors： Redwood AJ,Pavlos RK,White KD,Phillips EJ

更新日期：2018-01-01 00:00:00

abstract：:HLA-A*02:934 has one nucleotide change from HLA-A*02:01:01:01 at nucleotide 308. ...

journal_title：HLA

authors： Ananeva A,Shaihutdinova A,Andryushkina A,Shagimardanova E

更新日期：2020-11-26 00:00:00

abstract：:The novel allele, HLA-B*15:388, was identified in a Chinese bone marrow donor by sequence-based typing. ...

journal_title：HLA

authors： Han B,Zhu YL,Guo QM,Pang ST,Feng ZH

更新日期：2018-02-01 00:00:00

abstract：:DRB1*15:175 differs from DRB1*15:01:01:02 by one nucleotide substitution at position 233 in exon 2. ...

journal_title：HLA

authors： Genebrier S,Elsermans V,Nivet C,Chérel M,Renac V

更新日期：2020-12-01 00:00:00

abstract：:A single nucleotide change in HLA-DPA1*01:03:01:01 results in the novel null allele, HLA-DPA1*01:29N. ...

journal_title：HLA

authors： Keppen C,Therie D,Keppen J,Khamo V,Kanga U

更新日期：2020-01-01 00:00:00

abstract：:We have developed a protocol regarding the genomic characterization of the MICA gene by next generation sequencing (NGS). The amplicon includes the full length of the gene and is about 13 kb. A total of 156 samples were included in the study. Ninety-seven of these samples were previously characterized at MICA by legac...

journal_title：HLA

authors： Zou Y,Duke JL,Ferriola D,Luo Q,Wasserman J,Mosbruger TL,Luo W,Cai L,Zou K,Tairis N,Damianos G,Pagkrati I,Kukuruga D,Huang Y,Monos DS

更新日期：2020-10-01 00:00:00

abstract：:HLA are functional in cancer immunosurveillance in adaptive and innate immunity pathways. In unrelated hematopoietic stem cell transplantation (HSCT) in 688 patients with hematological malignancies we compared antitumor efficacy of transplant in three models including the level of: (a) donor-recipient HLA class I mism...

journal_title：HLA

authors： Graczyk-Pol E,Rogatko-Koros M,Nestorowicz K,Gwozdowicz S,Mika-Witkowska R,Pawliczak D,Zubala M,Szlendak U,Witkowska A,Tomaszewska A,Nasilowska-Adamska B,Szczepinski A,Wojcik M,Halaburda K,Nowak J

更新日期：2018-12-01 00:00:00

abstract：:A*30:154 differs from A*30:01:01:01 by one nucleotide substitution at codon 39 in exon 2 from C to A. ...

journal_title：HLA

authors： Zhong XX,Quan ZR,Zeng XH,Zhang CL,Wu WD

更新日期：2020-11-01 00:00:00

abstract：:One of the fundamental hallmarks of cancer is the incapacity of the immune system to eliminate malignancy. Cytotoxic T-lymphocyte antigen-4 (CTLA-4) and lymphocyte activation gene-3 (LAG-3) are considered major inhibitory immune checkpoints expressed on T cells. In this study, we investigated mRNA expression of CTLA-4...

journal_title：HLA

authors： Radwan SM,Elleboudy NS,Nabih NA,Kamal AM

更新日期：2020-07-01 00:00:00

abstract：:HLA-B*08:242 differs from HLA-B*08:01:01:01 in codons 33 and 36 of exon 2. ...

journal_title：HLA

authors： Alburaq M,AlSebaiheen F,Alblaihed A,Alshubaili A,Hajeer AH

更新日期：2019-10-01 00:00:00

abstract：:The killer cell lectin-like receptor B1 (KLRB1) gene encodes for CD161 expressed by different subsets of leukocytes involved in the development of acute liver transplant rejection. The single nucleotide polymorphism (SNP) 503T>C (rs1135816) in the KLRB1 gene represents a missense mutation modifying functional properti...

journal_title：HLA

authors： Thude H,Rother S,Sterneck M,Klempnauer J,Nashan B,Schwinzer R,Koch M

更新日期：2018-01-01 00:00:00

abstract：:HLA-B*07:381 differs from B*07:02:01:01 by one nucleotide substitution at position 1046 in exon 7. ...

journal_title：HLA

authors： Genebrier S,Elsermans V,Texeraud E,Bertrand G,Renac V

更新日期：2020-12-01 00:00:00

abstract：:HLA-B*13:69 allele differs from B*13:02:01 by one nucleotide substitution at position 628 from A to C. ...

journal_title：HLA

authors： Zheng JW,Xie JH,Sun Y,Jiang YQ,Xiang D

更新日期：2016-09-01 00:00:00

abstract：:One nucleotide replacement at residue 221 of HLA-B*15:18:01:01 results in a new allele, HLA-B*15:414. ...

journal_title：HLA

authors： Yang KL,Lin PY

更新日期：2017-04-01 00:00:00

abstract：:HLA-C*03:02:17 differs from HLA-C*03:02:02:01 by one nucleotide substitution at position 393. ...

journal_title：HLA

authors： Zhang LQ,Xiao Y,Zhou XY,Cai JP

更新日期：2018-04-25 00:00:00

abstract：:One nucleotide substitution at nucleotide 594 of HLA-DRB1*14:54:01:01 results in a novel allele, HLA-DRB1*14:227. ...

journal_title：HLA

authors： Yang KL,Li CC,Lin PY

更新日期：2021-02-01 00:00:00

abstract：:One nucleotide replacement at nucleotide 811 of HLA-A*02:01:01:01 results in a new allele, HLA-A*02:692. ...

journal_title：HLA

authors： Zhu YL,Han B,Chi XY,Hu B,Feng ZH

更新日期：2018-01-01 00:00:00

abstract：:Mixed connective tissue disease (MCTD) is a systemic autoimmune disease, originally defined as a connective tissue inflammatory syndrome with overlapping features of systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), polymyositis/dermatomyositis (PM/DM) and systemic sclerosis (SSc), characterized by the pr...

journal_title：HLA

authors： Paradowska-Gorycka A,Stypińska B,Olesińska M,Felis-Giemza A,Mańczak M,Czuszynska Z,Zdrojewski Z,Wojciechowicz J,Jurkowska M

更新日期：2016-01-01 00:00:00

abstract：:B*44:476 differs from B*44:03:01:01 by one nucleotide substitution at position 934 in exon 5. This article is protected by copyright. All rights reserved. ...

journal_title：HLA

authors： Genebrier S,Elsermans V,Texeraud E,Bertrand G,Renac V

更新日期：2020-08-14 00:00:00

abstract：:The novel allele HLA-C*16:123N has a single nucleotide difference with HLA-C*01:02:01:01 in exon 2. ...

journal_title：HLA

authors： Al Yafei Z,Alvares MS,Alkatheeri LM,Al Mahri A,ElGhazali G

更新日期：2019-06-01 00:00:00

abstract：:B*35:460Q differs from B*35:03:01:01 by one nucleotide substitution at position 406 in exon 3. ...

journal_title：HLA

authors： Genebrier S,Elsermans V,Nivet C,Chérel M,Renac V

更新日期：2020-08-10 00:00:00

abstract：:The new HLA-B*15:583 and DRB1*11:279 alleles identified in Buryat and Russian individuals, respectively. ...

journal_title：HLA

authors： Loginova M,Makhova O,Kutyavina S,Paramonov I,Zarubin M

更新日期：2021-01-20 00:00:00

abstract：:One nucleotide substitution at residue 19 of HLA-C*03:03:01:01 results in a novel allele, HLA-C*03:227. ...

journal_title：HLA

authors： Yang KL,Lin PY

更新日期：2017-04-01 00:00:00

abstract：:HLA-C*02:185 differs from HLA-C*02:02:02:01 by one nucleotide substitution at codon 180 in exon 3. ...

journal_title：HLA

authors： Dard C,Senoussi O,Elsermans V,Bardy B,Masson D

更新日期：2020-09-01 00:00:00

abstract：:HLA-DRB3*02:02:25 differs from HLA-DRB3*02:02:01:02 by one nucleotide substitution in codon 116 in exon 3. ...

journal_title：HLA

authors： Cargou M,Andreani M,Troiano M,Ralazamahaleo M,Visentin J

更新日期：2020-09-01 00:00:00

abstract：:Innate lymphoid cells (ILCs) are a new class of immune cells that include natural killer (NK) cells and appear to be the innate counterparts to CD4(+) helper T cells and CD8(+) cytotoxic T cells based on developmental and functional similarities. Like T cells, both NK cells and other ILCs also show connections to the ...

journal_title：HLA

authors： Robinette ML,Colonna M

更新日期：2016-01-01 00:00:00

abstract：:HLA-C*06:66 differs from HLA-C*06:02:01:01 in codon 151 in exon 3. ...

journal_title：HLA

authors： Baek IC,Choi EJ,Shin DH,Kim HJ,Kim TG

更新日期：2018-11-01 00:00:00

abstract：:The novel KIR3DL3*04802 allele differs from the closest allele KIR3DL3*04801 by a single synonymous mutation. ...

journal_title：HLA

authors： Deng ZH,Zhang GB,Chen R

更新日期：2017-01-01 00:00:00

abstract：:Allogeneic stem cell transplantation is a form of immunotherapy that has increased the chances of survival for patients with relapsed leukemia and high risk leukemia in remission. The major obstacles are graft-vs-host disease (GVHD) involving vital organs and infections. A most efficacious prophylaxis of GVHD is by de...

journal_title：HLA

authors： Kolb HJ

更新日期：2017-05-01 00:00:00

abstract：:The role of de novo donor-specific anti-human leukocyte antigen (anti-HLA) antibodies (dnDSA) within the pathways leading to graft failure remains not fully understood. We investigated 56 patients who were transplanted between 2002 and 2014 with kidney graft failure (cases), for a possible association of development o...

journal_title：HLA

authors： Castro A,Malheiro J,Tafulo S,Dias L,Martins LS,Fonseca I,Beirão I,Castro-Henriques A,Cabrita A

更新日期：2017-11-01 00:00:00