当前位置： SCI文献检索 > JOURNAL OF ASSISTED REPRODUCTION AND GENETICS期刊下所有文献 > Could monopronucleated ICSI zygotes be considered for transfer? Analysis through time-lapse monitoring and PGS.

Could monopronucleated ICSI zygotes be considered for transfer? Analysis through time-lapse monitoring and PGS.

Abstract：

PURPOSE:The purpose of this study was to investigate the chromosomal constitution and the developmental potential of intracytoplasmic sperm injection (ICSI) deriving embryos displaying a single pronucleus at the zygote stage. METHODS:Eighty-eight embryos from single pronucleus (1PN) two polar bodies (2PB) ICSI zygotes from 64 preimplantational genetic screening (PGS) cycles (October 2012-December 2014), were retrospectively analyzed. Zygotes were cultured in a time-lapse incubator. Embryo biopsy was performed on day 3 and genetic analysis approached by array comparative genomic hybridization. RESULTS:Chromosomal analysis revealed that 17% (15/88) of embryos derived from 1PN 2PB zygotes were diagnosed as euploid. After blastomere biopsy at day 3, the blastocyst rate at day 5 was 3.4% (3/88). Only 2.3% (2/88) euploid blastocysts were obtained. In two couples and after counseling and patient agreement, the transfer of a euploid blastocyst from a 1PN 2PB ICSI zygote was performed resulting in the birth of a healthy child. CONCLUSIONS:These results open the possibility to consider embryos coming from 1PN 2PB ICSI zygotes for transfer when no other embryos from 2PN 2PB ICSI zygotes are available and if a PGS diagnosis of euploidy is obtained. Confirmation of biparental inheritance is strongly recommended.

journal_name

J Assist Reprod Genet

journal_title

Journal of assisted reproduction and genetics

authors

Mateo S,Vidal F,Parriego M,Rodríguez I,Montalvo V,Veiga A,Boada M

doi

10.1007/s10815-017-0937-z

subject

Has Abstract

pub_date

2017-07-01 00:00:00

pages

905-911

issue

7

eissn

1058-0468

issn

1573-7330

pii

10.1007/s10815-017-0937-z

journal_volume

34

pub_type

杂志文章

相关文献

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS文献大全
  • Is there any evidence for immunologically mediated or immunologically modifiable early pregnancy failure?

    abstract：PURPOSE:Human reproduction is an inefficient process. There is a high rate of loss of early pregnancies, often before the mother (or physician) knows she is pregnant. Genetic abnormalities can explain much of the wastage, but can it explain all of the failures? As embryos bear paternal and embryonic antigens foreign to...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,评审

    doi：10.1023/a:1021788024214

    authors： Clark DA

    更新日期：2003-02-01 00:00:00

  • Extracellular microRNA profiling in human follicular fluid: new biomarkers in female reproductive potential.

    abstract：:MicroRNAs (miRNAs) are small, about 22 nucleotides, non-coding RNAs which regulate a wide range of gene expression during post-transcriptional stage. They are released into intra- and extracellular microenvironments and play vital roles in different physiological and pathological pathways. Due to easy accessibility, d...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,评审

    doi：10.1007/s10815-020-01860-0

    authors： Qasemi M,Amidi F

    更新日期：2020-08-01 00:00:00

  • Efficacy of low-dose human chorionic gonadotropin (hCG) in a GnRH antagonist protocol.

    abstract：PURPOSE:To examine the efficacy of low-dose hCG using a GnRH antagonist protocol. METHODS:Prospective randomized study was performed at the Kyono Ladies Clinic. One hundred ninety-two women (<40 -years old, <3 previous cycles) were randomly assigned to GnRH agonist (buserelin) long protocol (LP, n = 66), GnRH antagoni...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s10815-006-9036-2

    authors： Koichi K,Yukiko N,Shima K,Sachiko S

    更新日期：2006-05-01 00:00:00

  • "One for Sorrow, Two for Joy?": American embryo transfer guideline recommendations, practices, and outcomes for gestational surrogate patients.

    abstract：:In January 2016, Melissa Cook, a California gestational surrogate experiencing a multiple-birth pregnancy following the in vitro fertilization (IVF) transfer of three embryos comprised of donor eggs and sperm provided by the intended father, went to the media when the intended father requested that she undergo a fetal...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,评审

    doi：10.1007/s10815-017-0885-7

    authors： White PM

    更新日期：2017-04-01 00:00:00

  • Endometriosis does not affect live birth rates of patients submitted to assisted reproduction techniques: analysis of the Latin American Network Registry database from 1995 to 2011.

    abstract：PURPOSE:The purpose of this study is to compare the results of ART treatment in patients with and without endometriosis in a large cohort of patients from different centers over an extented period of time. METHODS:This retrospective study is using data from patients undergoing 27,294 cycles of IVF/ICSI treatment betwe...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-018-1214-5

    authors： Murta M,Machado RC,Zegers-Hochschild F,Checa MA,Sampaio M,Geber S

    更新日期：2018-08-01 00:00:00

  • Reproductive ovarian testing and the alphabet soup of diagnoses: DOR, POI, POF, POR, and FOR.

    abstract：:There are large variations in the number of oocytes within each woman, and biologically, the total quantity is at its maximum before the woman is born. Scientific knowledge is limited about factors controlling the oocyte pool and how to measure it. Within fertility clinics, there is no uniform agreement on the diagnos...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,评审

    doi：10.1007/s10815-017-1058-4

    authors： Pastore LM,Christianson MS,Stelling J,Kearns WG,Segars JH

    更新日期：2018-01-01 00:00:00

  • Intracytoplasmic injection using spermatids and subsequent pregnancies: round versus elongated spermatids.

    abstract：:The purpose of this clinical trial study was to report the outcome of intracytoplasmic injection of round (RS) and elongated (ES) spermatids retrieved from the testis of nonobstructive men. Seven and three cycles using RS and ES injections were performed, respectively. Only one cycle utilizing the late stage of ES (Sd...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 临床试验,杂志文章

    doi：10.1023/a:1014447731630

    authors： Khalili MA,Aflatoonian A,Zavos PM

    更新日期：2002-02-01 00:00:00

  • The influence of uterine position on pregnancy rates with in vitro fertilization-embryo transfer.

    abstract：:We found no difference in clinical pregnancy rates following IVF-ET in women with anteverted versus retroverted uteri. Patients can be reassured that the probability of clinical pregnancy following IVF-ET is not compromised by uterine position. ...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/BF02215722

    authors： Agarwal SK,Coe S,Buyalos RP

    更新日期：1994-07-01 00:00:00

  • A distribution of two SNPs in exon 10 of the FSHR gene among the women with a diminished ovarian reserve in Ukraine.

    abstract：PURPOSE:To evaluate the association between phenotype and follicle stimulating hormone receptor (FSHR) genotype in women with ovarian dysfunction and patients with "poor response" to gonadotropin stimulation of ovulation. METHODS:FSHR gene SNPs were analyzed by PCR and RFLP. "Poor responders" (ovarian dysfunction) gro...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-008-9279-1

    authors： Livshyts G,Podlesnaja S,Kravchenko S,Sudoma I,Livshits L

    更新日期：2009-01-01 00:00:00

  • Vitamin D and assisted reproduction: should vitamin D be routinely screened and repleted prior to ART? A systematic review.

    abstract：PURPOSE:To review the current literature regarding the role of vitamin D status in pregnancy outcomes in women undergoing assisted reproductive technology (ART) and to assess cost-effectiveness of routine vitamin D deficiency screening and repletion prior to initiation of ART. METHODS:A systematic literature review wa...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,评审

    doi：10.1007/s10815-014-0407-9

    authors： Pacis MM,Fortin CN,Zarek SM,Mumford SL,Segars JH

    更新日期：2015-03-01 00:00:00

  • Eleven healthy live births: a result of simultaneous preimplantation genetic testing of α- and β-double thalassemia and aneuploidy screening.

    abstract：PURPOSE:To evaluate the efficacy of preimplantation genetic testing (PGT) for α- and β-double thalassemia combined with aneuploidy screening using next-generation sequencing (NGS). METHODS:An NGS-based PGT protocol was performed between 2017 and 2018 for twelve couples, each of which carried both α- and β-thalassemia ...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-020-01732-7

    authors： Chen D,Shen X,Wu C,Xu Y,Ding C,Zhang G,Xu Y,Zhou C

    更新日期：2020-03-01 00:00:00

  • IL-1β predicts IVF outcome: a prospective study.

    abstract：PURPOSE:Retrospective cohort studies have shown a relationship between maternal serum interleukin-1β (IL-1β) and interleukin-1 receptor antagonist (IL-1Ra) levels and in vitro fertilization (IVF) cycle outcome. The objective of this investigation was to explore the correlation between serum IL-1β and/or IL-1Ra levels o...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-018-1296-0

    authors： Kreines FM,Nasioudis D,Minis E,Irani M,Witkin SS,Spandorfer S

    更新日期：2018-11-01 00:00:00

  • Zona thinning with noncontact diode laser in patients aged < or = 37 years with no previous failure of implantation: a prospective randomized study.

    abstract：PURPOSE:Zona thinning (ZT) is a technique used to improve pregnancy rates among patients > or = 38 years old and/or patients presenting previous implantation failure. The objective of the study was to determine whether ZT has a beneficial effect on patients younger than 37 years who are undergoing the first ICSI attemp...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1023/a:1026481729632

    authors： Baruffi RL,Mauri AL,Petersen CG,Ferreira RC,Coelho J,Franco JG Jr

    更新日期：2000-11-01 00:00:00

  • Beneficial effect of desialylated erythropoietin administration on the frozen-thawed canine ovarian xenotransplantation.

    abstract：PURPOSE:The main drawback of ovarian cryopreservation followed by transplantation is that a large proportion of follicles are lost after transplantation. Thus, effects of erythropoietin (EPO) and desialylated EPO administration on the frozen-thawed canine ovarian xenotransplantation were examined. METHODS:The protecti...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-008-9271-9

    authors： Suzuki H,Ishijima T,Maruyama S,Yanagimoto Ueta Y,Abe Y,Saitoh H

    更新日期：2008-11-01 00:00:00

  • Pelvic abscess complicating an in vitro fertilization pregnancy and review of the literature.

    abstract：INTRODUCTION:In vitro fertilisation has become a very common procedure in the infertility practice due to both accessibility and good success rates. DISCUSSION:Complications, however, are constant reminders that no procedure is totally safe. In this paper, we present a case of IVF pregnancy that presented with pelvic ...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-008-9222-5

    authors： Al-Kuran O,Beitawi S,Al-Mehaisen L

    更新日期：2008-07-01 00:00:00

  • Human oocyte maturity in vivo determines the outcome of blastocyst development in vitro.

    abstract：PURPOSE:To date, the impact of oocyte maturity at aspiration on the blastocyst formation in vitro has not been fully evaluated. This study was undertaken to assess the influence of oocyte maturity in patients undergoing in vitro fertilization and blastocyst transfer program. METHODS:A total of 1278 oocytes derived fro...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1023/b:jarg.0000013651.37866.0c

    authors： Lin YC,Chang SY,Lan KC,Huang HW,Chang CY,Tsai MY,Kung FT,Huang FJ

    更新日期：2003-12-01 00:00:00

  • Assisted reproduction counseling in women aged 40 and above: a cohort study.

    abstract：PURPOSE:Fertility treatment in women aged ≥40 year old remains difficult and controversial. All available studies in older women report results of one specific method of ART, i.e. IUI, IVF/ICSI or oocyte donation, and success rates are always published per attempt but never per patient. Randomized studies are not avail...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-013-0085-z

    authors： De Brucker M,Tournaye H,Haentjens P,Verheyen G,Collins J,Camus M

    更新日期：2013-11-01 00:00:00

  • A proteomic analysis of human follicular fluid: comparison between fertilized oocytes and non-fertilized oocytes in the same patient.

    abstract：PURPOSE:Human follicular fluid constitutes the microenvironment of follicles and includes various biological active proteins that can affect follicle growth and oocyte fertilization. Conducting proteomic evaluations of human follicular fluid may be helpful for identifying potential biomarkers possibly possessing a pred...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-013-0004-3

    authors： Bayasula,Iwase A,Kobayashi H,Goto M,Nakahara T,Nakamura T,Kondo M,Nagatomo Y,Kotani T,Kikkawa F

    更新日期：2013-09-01 00:00:00

  • Meta-analysis of the association of AhR Arg554Lys, AhRR Pro185Ala, and ARNT Val189Val polymorphisms and endometriosis risk in Asians.

    abstract：PURPOSE:Several studies have suggested an association between the polymorphisms AhR Arg554Lys, AhRR Pro185Ala, and ARNT Val189Val and endometriosis, but results have been inconclusive. The aim of the present study was to assess these associations by meta-analysis. METHODS:Eligible literatures were retrieved from PubMe...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,meta分析

    doi：10.1007/s10815-015-0505-3

    authors： Zheng NN,Bi YP,Zheng Y,Zheng RH

    更新日期：2015-07-01 00:00:00

  • Gene expression of transforming growth factor-alpha in human endometrium during decidualization.

    abstract：PURPOSE:We previously reported the gene expression of epidermal growth factor (EGF) in the process of decidualization in the human endometrium. This study was undertaken to investigate the biological significance of transforming growth factor-alpha (TGF-alpha), which shares a significant sequence homology with EGF, in ...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/BF02766113

    authors： Taga M,Sakakibara H,Suyama K,Ikeda M,Minaguchi H

    更新日期：1997-04-01 00:00:00

  • Adjusted mitochondrial DNA quantification in human embryos may not be applicable as a biomarker of implantation potential.

    abstract：OBJECTIVE:To evaluate the feasibility of adjusted mitochondrial DNA quantification in human embryos as a biomarker for implantation potential. DESIGN:Double-blind, observational, prospective analysis of an Asian population in a single university-affiliated in vitro fertilization center. A total of 1617 embryos derived...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-019-01542-6

    authors： Lee YX,Chen CH,Lin SY,Lin YH,Tzeng CR

    更新日期：2019-09-01 00:00:00

  • Variability in follicular fluid high density lipoprotein particle components measured in ipsilateral follicles.

    abstract：PURPOSE:The purpose of this study was to examine the biological variability of follicular fluid (FF) high density lipoprotein (HDL) particle components measured in ipsilateral ovarian follicles. METHODS:We collected FF from two ipsilateral follicles among six women undergoing in vitro fertilization (IVF). We measured ...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-016-0648-x

    authors： Kim K,Bloom MS,Fujimoto VY,Bell EM,Yucel RM,Browne RW

    更新日期：2016-03-01 00:00:00

  • Identification of common mechanisms between endometriosis and ovarian cancer.

    abstract：PURPOSE:To determine common molecular markers between endometriosis and ovarian cancer. METHODS:Patients included women who underwent laparoscopic excision of ovarian endometriotic lesions (n = 7), healthy non-pregnant women with normal pelvises, who underwent excision of normal peritoneum (n = 7). Two epithelial ovar...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-011-9573-1

    authors： Meng Q,Sun W,Jiang J,Fletcher NM,Diamond MP,Saed GM

    更新日期：2011-09-01 00:00:00

  • Diagnostic laparoscopy in primary and secondary infertility.

    abstract：PURPOSE:Our purpose was to compare the diagnostic efficacy of laparoscopy between primary and secondary infertility and to define a subgroup in which the positive findings are low. METHODS:A retrospective review of the cases of 206 infertile women who underwent laparoscopy was conducted. RESULTS:Eighty-two (39.8%) pa...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1023/a:1022578019260

    authors： Hovav Y,Hornstein E,Almagor M,Yaffe C

    更新日期：1998-10-01 00:00:00

  • Endometrial preparation for in vitro oocyte maturation: early use of estrogen increases endometrial tissue and requires lower daily dosage: a cross over trial in 'mock' cycles.

    abstract：PURPOSE:Determine if estrogen used since the beginning of the menstrual flow could improve endometrial tissue compared to standard endometrial preparation for in vitro maturation cycles. METHODS:Twenty polycystic ovary syndrome women were submitted to two estrogen therapy schedules: standard schedule; estrogen began o...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章,随机对照试验

    doi：10.1007/s10815-006-9042-4

    authors： Martins Wde P,dos Reis RM,Ferriani RA,de Araújo CH,Nastri CO,Filho FM

    更新日期：2006-05-01 00:00:00

  • Study of the optimum time for human chorionic gonadotropin-ovum pickup interval in in vitro fertilization.

    abstract：OBJECTIVE:To study the optimum time for ovum pickup after human chorionic gonadotropin (hCG) injection in in vitro fertilization. DESIGN:Prospective randomized study. SETTING:The Egyptian IVF-ET center. PATIENTS:Ninety couples with male factor infertility enrolled for intracytoplasmic sperm injection, divided into t...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1007/BF02215712

    authors： Mansour RT,Aboulghar MA,Serour GI

    更新日期：1994-10-01 00:00:00

  • Positive association of Apolipoprotein E4 polymorphism with recurrent pregnancy loss in Iranian patients.

    abstract：PROBLEM:Numerous lines of evidence implicate Apolipoprotein E (Apo E) in lipid metabolism during pregnancy. Hence, a role for its polymorphism has been envisaged in recurrent pregnancy loss (RPL) considering major structural and functional differences between different Apo E genotypes. METHOD OF STUDY:A case control s...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-012-9897-5

    authors： Asgari N,Akbari MT,Zare S,Babamohammadi G

    更新日期：2013-02-01 00:00:00

  • The prevalence of ureaplasma urealyticum, mycoplasma hominis, chlamydia trachomatis and neisseria gonorrhoeae infections, and the rubella status of patients undergoing an initial infertility evaluation.

    abstract：PURPOSE:To determine the prevalence of positive test for Ureaplasma urealyticum (UU), Mycoplasma hominis (MH), Chlamydia trachomatis (CT), Neisseria gonorrhoeae (NG) infections, and their corresponding Rubella status when undergoing workup for infertility. METHODS:Retrospective chart review to determine infection stat...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-007-9192-z

    authors： Imudia AN,Detti L,Puscheck EE,Yelian FD,Diamond MP

    更新日期：2008-01-01 00:00:00

  • Obesity results with smaller oocyte in in vitro fertilization/intracytoplasmic sperm injection cycles-a prospective study.

    abstract：BACKGROUND:Obesity is associated with several fertility disorders. This prospective cohort study was designed to evaluate the effect of body mass index (BMI) (kg/m2) on oocyte diameter and treatment. METHODS:Women undergoing in vitro fertilization (IVF) with intracytoplasmic sperm injection (ICSI) were enrolled in the...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-017-0975-6

    authors： Atzmon Y,Shoshan-Karchovsky E,Michaeli M,Aslih N,Shrem G,Ellenbogen A,Shalom-Paz E

    更新日期：2017-09-01 00:00:00

  • Aneuploidy across individual chromosomes at the embryonic level in trophectoderm biopsies: changes with patient age and chromosome structure.

    abstract：PURPOSE:To characterize each chromosome's risk for being involved in embryonic aneuploidy. METHODS:This is a retrospective cohort study conducted at a single, academic center. The cohort consisted of 15,169 consecutive trophectoderm biopsies which then underwent comprehensive chromosome screening utilizing validated r...

    journal_title：Journal of assisted reproduction and genetics

    pub_type： 杂志文章

    doi：10.1007/s10815-014-0333-x

    authors： Franasiak JM,Forman EJ,Hong KH,Werner MD,Upham KM,Treff NR,Scott RT

    更新日期：2014-11-01 00:00:00