Abstract:
BACKGROUND:Today, despite the many advances in early detection of diseases, cancer patients have a poor prognosis and the survival rates in them are low. Recently, microarray technologies have been used for gathering thousands data about the gene expression level of cancer cells. These types of data are the main indicators in survival prediction of cancer. This study highlights the improvement of survival prediction based on gene expression data by using machine learning techniques in cancer patients. METHODS:This review article was conducted by searching articles between 2000 to 2016 in scientific databases and e-Journals. We used keywords such as machine learning, gene expression data, survival and cancer. RESULTS:Studies have shown the high accuracy and effectiveness of gene expression data in comparison with clinical data in survival prediction. Because of bewildering and high volume of such data, studies have highlighted the importance of machine learning algorithms such as Artificial Neural Networks (ANN) to find out the distinctive signatures of gene expression in cancer patients. These algorithms improve the efficiency of probing and analyzing gene expression in cancer profiles for survival prediction of cancer. CONCLUSION:By attention to the capabilities of machine learning techniques in proteomics and genomics applications, developing clinical decision support systems based on these methods for analyzing gene expression data can prevent potential errors in survival estimation, provide appropriate and individualized treatments to patients and improve the prognosis of cancers.
journal_name
Iran J Public Healthjournal_title
Iranian journal of public healthauthors
Bashiri A,Ghazisaeedi M,Safdari R,Shahmoradi L,Ehtesham Hsubject
Has Abstractpub_date
2017-02-01 00:00:00pages
165-172issue
2eissn
2251-6085issn
2251-6093journal_volume
46pub_type
杂志文章,评审abstract:BACKGROUND:Bladder cancer is the most frequent genitourinary malignancy in Iran. Environmental and genetic factors are the two factors linked with bladder cancer expansion. The aim of this study was to investigate the role of PTEN gene and environmental risk factors on the progression and prognosis of bladder cancer. ...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2014-01-01 00:00:00
abstract:Background:We aimed to determine the level of computer game addiction and loneliness among 9-10-yr-old children. Methods:The study was conducted with 4th-grade students at a primary school, located at the city center, during 2017-2018 academic years. There was no sampling in the research, all 4th-grade students of the...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2018-10-01 00:00:00
abstract:Background:To survey the prevalence of potential drug-drug interactions (DDIs) between anticancer drugs and non-anticancer drugs and evaluate the risk factors associated with these drug-drug interactions in China. Methods:All discharged patients in the Department of Oncology were collected from Jun to Dec in 2016 with...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2019-03-01 00:00:00
abstract:Background:β-thalassemia is characterized by reduced synthesis of the hemoglobin beta chain that results in microcytic hypochromic anemia and reduced amounts of hemoglobin A (HbA) on hemoglobin analysis. β-thalassemias are caused by mutations in the β-globin gene, inherited in an autosomal recessive manner. Determining...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate the trends in mortality from road traffic accidents (RTA) in Fars Province, southern Iran. METHODS:The Age and sex-standardized mortality rate attributed to RTA from 2004 to 2010 in Fars Province was calculated using world standard population. We also used linear reg...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:There are more than 350 wastewater treatment plants distributed across different parts of Oman. Some of them produce large quantities of domestic sewage sludge, particularly this study focused on characterizing domestic sludge of six treatment plants that may contain various pollutants, therefore the proper ...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:Iodine is essential element in thyroid hormones synthesis and normal growth and development of the brain. Milk and iodine concentrations can be appropriate indicator of body iodine status; in this study, we evaluated the concentrations of urine and milk iodine in newborns and their mothers. METHODS:In a cro...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Regarding the need for scientific development and achievement our national goals, it is clear that international cooperation has the main role in this way. Here is a report on what we have done during past almost 10 years (2001-2011) in the field of international medical research activities in Deputy Ministr...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
abstract::Nowadays, medical tourism reports impressive growth in terms of number of persons, income and number of countries involved in cross-border flows. So this study was undertaken to clarify entrepreneurship opportunities and bio-ethics boundaries in medical tourism. For tourism entrepreneurs, these outgoing flows related ...
journal_title:Iranian journal of public health
pub_type: 杂志文章,评审
doi:
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:The objective was to measure the sensitivity of a group of physicians regarding the ethics-related situations, which they faced during patient care and treatment. METHODS:All of 306 physicians who joined the Turkish Army for compulsory military service in December 2008 were included in the study. A "Moral S...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Chinese medical workers suffer from a high incidence of mental health problems, resulting in reduced efficiency, increased medical malpractice, rising medical costs, and other issues. The effective alleviation of mental health problems among medical workers is therefore an important focus of research and soc...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:We aimed to study the curative effects of botulinum A toxin (BTX-A) on the treatment of post-herpetic neuralgia (PNH). METHODS:We enrolled 58 PNH patients and treated them with hypodermic injection of BTX-A in Xiangyang No.1 People's Hospital, Hubei University of Medicine, Hubei, China. We measured and comp...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:Fascioliasis, caused by Fasciola hepatica and F. gigantica, is one of the most important plant and water borne disease in Iran. This study aimed to determine the prevalence of fascioliasis and intestinal helminthes in inhabitants of rural areas of Boyer-Ahmad in Kohgiluyeh and Boyer-Ahmad province in Southwe...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2015-11-01 00:00:00
abstract:Background:This paper investigated the impact of hospitals' horizontal integration in the Czech Republic on the cost behavior. The aim of the research was to examined the hospitals costs in specific environment of region hospitals at NUTS 3 level (Nomenclature of Units for Territorial Statistics) - Administrative Regio...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2019-11-01 00:00:00
abstract::Herein we report three married women referred to Dermatology Clinic of Loghman Hakim Hospital, Tehran, Iran in 2017 for evaluation and treatment of genital warts. Two patients were complaining of flat-topped papules on their labia major and the third one was presented with asymptomatic papillary projections on her ves...
journal_title:Iranian journal of public health
pub_type:
doi:
更新日期:2019-06-01 00:00:00
abstract::Mendelian susceptibility to mycobacterial diseases (MSMD) is a rare inheritance syndrome, characterized by a disseminated infection with mycobacterium in children following BCG vaccination at birth. Regarding the vaccination program in Iran, it may consider as a public health problem. The pathogenesis of MSMD is depen...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:Transition into parenthood is a major developmental life event and is very significant because development in infanthood is affected by the transition process of mothers parenting an infant. This study aimed to develop the assessment tool for transition process of high risk infant's caregiver in Korea. METH...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2016-02-01 00:00:00
abstract::Background Cutaneous leishmaniasis is the most common form of leishmaniasis caused by flagellate protozoa of the genus Leishmania transmitted by sand fly bites. Old World leishmaniasis is endemic in the Mediterranean Sea and the neighbouring countries. We believe, that this case is interesting by the fact that we had ...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2013-12-01 00:00:00
abstract:Background:We aimed to investigate the polluted working environment triggers oxidative stress and alter enzymatic antioxidant activity by a short-term interval. Methods:The experimental study, performed in 2014, involved 94 workers from the Velenje Coalmine in Slovenia, arranged into three groups according to a number...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2019-07-01 00:00:00
abstract:Background:As dyslipidemia is a preventable risk factor for Coronary heart disease (CHD), precise estimation of its prevalence and determinants is crucial for proper development of health actions. This population-based study aimed at investigating the socioeconomic, dietary and psychological determinants of dyslipidemi...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:According to importance of cirrhosis of the liver and the lack of information about the economic burden of the disease, we performed this study to estimate the economic burden of liver Cirrhosis in Iran in 2011. METHODS:The cost-of-illness method, based on the human capital theory, has been used. Both direc...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Immune responses play critical roles in the leishmaniasis eradication. IL-10 is a key regulator of immune responses, and the polymorphisms within its promoter region are associated with alteration in its expression. Therefore, this study was designed to examine the correlation between polymorphism at the -10...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:The Ministry of Health and Medical Education of Iran, along with the country movement towards achievements of Iran's Vision 2025 put compilation of the health system reform plan on its agenda. In this article, we are trying to show the method we used for developing this plan and how this method considered th...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
abstract:Background:The incidence of chronic diseases, such as cardiovascular disease, diabetes, overweight, obesity, cancer and other diseases has been increasing. It is a huge challenge to public health industry about how to provide risk intervention and preventive medical services and explore advanced technology platform for...
journal_title:Iranian journal of public health
pub_type: 杂志文章,评审
doi:
更新日期:2019-06-01 00:00:00
abstract:BACKGROUND:Metabolic syndrome (MS) is defined as a pattern of metabolic disorders including central obesity, insulin resistance or hyperglycemia, high blood pressure, and dyslipidemia. Many studies show a clear relationship between diet and components of MS. The aim of the current study was to identify barriers to adhe...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Metabolic syndrome (MS) is emerging as a serious public health problem in Korea. The purpose of this study was to examine the effects of 12 weeks of combined exercise training on body composition and MS factors in obese Korean female college students. METHODS:Subjects were randomly assigned to exercise (n =...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract:Background:Korean traditional nuruk, consisting of a variety of microorganisms, is widely used in traditional liquor materials. The present study evaluated the antimicrobial activity of strains isolated from Korean traditional nuruk in 2016. Methods:The strain was isolated from Korea traditional nuruk and performed an...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2018-11-01 00:00:00
abstract:Background:To investigate the determinants of smoking behavior among Iranian adolescents applying the Prototype/Willingness (P/W) Model. Methods:In this cross-sectional study, a self-administered P/W model-based questionnaire was completed between 760 randomly selected adolescents (high school students and dropouts) i...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2018-09-01 00:00:00
abstract::Since it was first diagnosed in 1914 in Marrakesh, schistosomiasis has been a public health problem in Morocco for decades. A national control program launched in 1982 has led to a considerable reduction in the incidence and morbidity associated with the disease. Consequently, the program has shifted from disease cont...
journal_title:Iranian journal of public health
pub_type: 杂志文章,评审
doi:
更新日期:2014-09-01 00:00:00
abstract:Background:The analysis of the residual contents of heavy and toxic metals in foodstuff especially milk could be an important indicator of safety, quality, and level of pollution of the region in which the milk was produced. Therefore, the present investigation was carried out to assess human health risk of residues le...
journal_title:Iranian journal of public health
pub_type: 杂志文章
doi:
更新日期:2018-08-01 00:00:00