Abstract：
BACKGROUND:Immune responses play critical roles in the leishmaniasis eradication. IL-10 is a key regulator of immune responses, and the polymorphisms within its promoter region are associated with alteration in its expression. Therefore, this study was designed to examine the correlation between polymorphism at the -1082 position of the IL-10 gene and visceral leishmaniasis (VL). METHODS:The IL-10 -1082 polymorphism and anti-Leishmania antibody titration were examined in 110 patients with clinical presentation of VL and seropositive for the Leishmania (group 1), 74 seropositive patients but without clinical presentation (group 2) and 113 healthy controls (group 3) using the PCR-RFLP and immunofluorescence techniques, respectively. RESULTS:The polymorphism at IL-10 -1082 (A/G) position was significantly associated with VL and A/G genotype was significantly higher in VL patients when compared to the groups 2 and 3 (P< 0.001). However, the results demonstrated that the A and G alleles were not associated with VL (P= 0.263). CONCLUSIONS:Previous investigations have shown that the polymorphism at the -1082 position of the IL-10 gene can influence its expression and also it has been proved that IL-10 level was increased during VL. Our results suggest that the A/G genotype may be considered as a risk factor for VL.
journal_name
Iran J Public Healthjournal_title
Iranian journal of public healthauthors
Hajilooi M,Ahmadi A,Lotfi P,Matini M,Jafari D,Bazmani A,Momeni Msubject
Has Abstractpub_date
2014-08-01 00:00:00pages
1107-12issue
8eissn
2251-6085issn
2251-6093journal_volume
43pub_type
杂志文章abstract：BACKGROUND:An explosion of research has been done in discovering how human health is affected by environmental factors. I will discuss the impacts of environmental cancer causing factors and how they continue to cause multiple disruptions in cellular networking. Some risk factors may not cause cancer. Other factors ini...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:Congenital toxoplasmosis is associated with variable complications including encephalitis, microcephaly, hydrocephaly, hepatitis, lymphadenopathy and even intrauterine death. Presence of Toxoplasma gondii in human placenta may induce congenital infection. The aim of this study was to determine the genotypes ...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2013-06-01 00:00:00
abstract：BACKGROUND:Limited studies have focused on the association between the protein tyrosine phosphates non-receptor type 22 (PTPN22) genetic polymorphisms and Juvenile idiopathic arthritis (JIA) susceptibility in different populations, but the results were inconclusive. Therefore, this meta-analysis of PTPN22 polymorphism ...
journal_title：Iranian journal of public health
pub_type： 杂志文章,评审
doi：
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:The purpose of this study was to determine the level of heat stress to construction workers using Thermal Work Limit (TWL) and Wet Bulb Globe Temperature (WBGT) indices and by measuring Urine Specific Gravity (USG) among construction workers in Iran and comparing the appropriateness of these indices for meas...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2014-04-01 00:00:00
abstract：BACKGROUND:Urogenital mycoplasmas are potentially pathogenic species causing genitourinary tract infections that may be initially asymptomatic but can progress and lead to severe complications and threaten reproductive health. However, the overall prevalence rate of this bacterium and its probable impacts on fertility ...
journal_title：Iranian journal of public health
pub_type： 杂志文章,评审
doi：
更新日期：2016-04-01 00:00:00
abstract：BACKGROUND:Group B streptococcus (GBS) is one of the most important cause of morbidity and mortality among newborns especially in developing countries. It has been shown that the screening approach rather than the identification of maternal clinical risk factors for early-onset neonatal GBS disease is more effective in...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：Background:Vitamin D might be promising to serve as an adjunctive therapy for pulmonary tuberculosis (TB). However, the results remained controversial. We conducted a systematic review and meta-analysis to evaluate the efficacy and safety of vitamin D in patients with pulmonary TB. Methods:Medline, SCOPUS, Google Scho...
journal_title：Iranian journal of public health
pub_type： 杂志文章,评审
doi：
更新日期：2018-04-01 00:00:00
abstract：:Coccidian protozoa of Cyclospora cayetanensis are obligate intracellular apicomplexan parasites that infect the mucosal epithelium of the small intestine of immunocompetent and immunocompromised persons. A 25- years old woman from around, Tehran with complaint of faintness and fatigue with HIV positive/AIDS confirmed ...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND:Neural tube defects (NTD) are one of the leading causes of infant mortality worldwide. This study was designed to determine the prevalence of NTDs among native Fars ethnic groups during 1998-2005, and to identify maternal and demographic factors associated with NTDs. METHODS:We performed a descriptive cross...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND:The aim of the present study was to evaluate the capability of helminths to absorb heavy metals in comparison with that of the host tissues. METHODS:We compared the concentration of cadmium (Cd) and chromium (Cr) in urban rats and in their harboring helminthes -Moniliformis moniliformis, Hymenolepis diminut...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:Child with Down's syndrome is an individual who is suitable and eligible to receive early intervention services. This study aimed to measure the family outcome among parents of Down syndrome children, on the impact of receiving early intervention and identify the factors influencing it. METHODS:A cross sect...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2013-09-01 00:00:00
abstract：Background:The National Health Insurance Service (NHIS) conducted a screening test to detect chronic diseases such as hypertension and diabetes in Korea. This study evaluated the effects of health screening for DM on pharmacological treatment. Methods:The data from qualification and the General Health Screening in 201...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2018-02-01 00:00:00
abstract：:Mendelian susceptibility to mycobacterial diseases (MSMD) is a rare inheritance syndrome, characterized by a disseminated infection with mycobacterium in children following BCG vaccination at birth. Regarding the vaccination program in Iran, it may consider as a public health problem. The pathogenesis of MSMD is depen...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2016-02-01 00:00:00
abstract：Background:We aimed to evaluate the efficacy of mineral trioxide aggregate (MTA) in the treatment of endodontic disease. Methods:Oversell, 384 patients with endodontic disease treated in Xuzhou Stomatological Hospital, Xuzhou, China, from June 2015 to June 2017 were selected, and randomly divided into four groups with...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2019-04-01 00:00:00
abstract：Background:Pseudoexfoliation syndrome (XFS) is pathogenetically related to exfoliative glaucoma (XFG), which is the most common type of secondary glaucoma. We aimed to investigate the relationship between LOXL1 SNPs (rs1048661, rs3825942) and XFS and/or XFG in a cohort of Iranian subjects. Methods:This cross-sectional...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:Iodine is essential element in thyroid hormones synthesis and normal growth and development of the brain. Milk and iodine concentrations can be appropriate indicator of body iodine status; in this study, we evaluated the concentrations of urine and milk iodine in newborns and their mothers. METHODS:In a cro...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2014-10-01 00:00:00
abstract：Background:The incidence of chronic diseases, such as cardiovascular disease, diabetes, overweight, obesity, cancer and other diseases has been increasing. It is a huge challenge to public health industry about how to provide risk intervention and preventive medical services and explore advanced technology platform for...
journal_title：Iranian journal of public health
pub_type： 杂志文章,评审
doi：
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:The present study aimed to identify the spatial distribution of tuberculosis and determine the TB control program parameters in the regions supervised by Shiraz University of Medical Sciences in 2006-2012. METHODS:The present ecological study was performed on 1797 TB patients in Shiraz University in 2006-20...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2015-09-01 00:00:00
abstract：Background:Unwanted pregnancy is a type of unplanned pregnancy that can endanger health of mother and child. This study aimed to determine the prevalence of unwanted pregnancy and its associated factors and consequences in Iran. Methods:This cross-sectional study was conducted in regions with low, moderate and high ri...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：10.18502/ijph.v49i8.3897
更新日期：2020-08-01 00:00:00
abstract：Background:β-thalassemia is characterized by reduced synthesis of the hemoglobin beta chain that results in microcytic hypochromic anemia and reduced amounts of hemoglobin A (HbA) on hemoglobin analysis. β-thalassemias are caused by mutations in the β-globin gene, inherited in an autosomal recessive manner. Determining...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:Detection of Plasmodium vivax specific antibodies with serological tests could be a valuable tool for epidemiological researches. Whereas P. vivax cannot be simply obtained in vitro, serological tests using total or semi-purified antigens are infrequently used. Given this restriction, the present study inves...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2015-01-01 00:00:00
abstract：BACKGROUND:Students emotional health and bullying behavior are receiving greater attention worldwide due to their long-term effects on students' health. The purpose of this study was to examine the relationships between perceived school climate, peer support, teacher support, school pressure and emotional health and bu...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2014-11-01 00:00:00
abstract：BACKGROUND:Rotaviruses cause diarrhea in infants and young children worldwide. Rotavirus outer capsid protein, VP7 is major neutralizing antigen that is important component of subunit vaccine to prevent rotavirus infection. Many efforts have been done to produce recombinant VP7 that maintain native characteristics. We ...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:Transition into parenthood is a major developmental life event and is very significant because development in infanthood is affected by the transition process of mothers parenting an infant. This study aimed to develop the assessment tool for transition process of high risk infant's caregiver in Korea. METH...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND:Cattle can be considered as an important source for herbicides through nutrition. Therefore, herbicide residue in animal products is a potential human exposure to herbicides causing public health problems in human life. Triazines are a group of herbicides primarily used to control broadleaf weeds in corn and...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2011-12-01 00:00:00
abstract：Background:The recognition of patient safety is now occupying a prominent place on the health policy agenda since medical errors can result in adverse events. The existence of confusing drug names is one of the most common causes of medication errors. In Iran, the General Office of Trademarks Registry (GOTR), for four ...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:Quality of life in post-menopausal women and menopausal symptoms are closely related concepts. Influence health education policy in order to promote health and adopt a menopause lifestyle requires alternative strategies, including health training programs with community - based interventions. The current stu...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2012-01-01 00:00:00
abstract：Background:There is no published study evaluating the performance of cumulative sum (CUSUM) algorithm on meningitis data with limited baseline period. This study aimed to evaluate the CUSUM performance in timely detection of 707 semi-synthetic outbreak days. Methods:Simulated outbreaks were generated using syndromic d...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2017-10-01 00:00:00
abstract：Background:This population-based study aimed at investigating the prevalence and associated factors of over-weight /obesity and abdominal obesity in Iran. Methods:The study population consists of 2818 inhabitant of the urban and regional area of East-Azerbaijan, Iran in 2015. The weight, height and waist circumference...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:The purpose of the present study was to evaluate the inequality of geographical distribution of non-cardiac intensive care beds in Iran using the Gini coefficient. METHODS:The population information of Iran's provinces in 2006 was obtained from The Statistical Center of Iran and the number of non-cardiac in...
journal_title：Iranian journal of public health
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
