Iron Mapping in Multiple Sclerosis.

Abstract:

:Increased iron deposition in cerebral deep gray matter has been considered a global marker for neurodegeneration in multiple sclerosis (MS); it scales with disease duration and severity. Iron accumulation in white matter and MS lesions might be more directly related to disease activity and has been discussed as a contributor to the inflammatory and neurodegenerative cascade. New insights into iron and MS are expected from MR imaging. We discuss findings from MR iron mapping proposed. Because of the confounding magnetic properties of myelin, iron mapping in white matter remains an unresolved issue.

journal_name

Neuroimaging Clin N Am

authors

Ropele S,Enzinger C,Fazekas F

doi

10.1016/j.nic.2016.12.003

subject

Has Abstract

pub_date

2017-05-01 00:00:00

pages

335-342

issue

2

eissn

1052-5149

issn

1557-9867

pii

S1052-5149(16)30127-7

journal_volume

27

pub_type

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