Serum from plasma rich in growth factors regenerates rabbit corneas by promoting cell proliferation, migration, differentiation, adhesion and limbal stemness.

abstract：PURPOSE:Tissue inhibitors of metalloproteinases (TIMPs) block the catalysis by matrix metalloproteinases (MMPs) and have additional biologic activities, including regulation of cell growth and differentiation, apoptosis, angiogenesis and oncogenesis. We investigated the expression levels of all the four human TIMPs and...

journal_title：Acta ophthalmologica

authors： Abu El-Asrar AM,Ahmad A,Bittoun E,Siddiquei MM,Mohammad G,Mousa A,De Hertogh G,Opdenakker G

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:Graves' ophthalmopathy (GO) involves autoimmune process resulting in proptosis, congestion, oedema and diplopia. Werner's NOSPECS classification and clinical activity score (CAS) of GO cannot objectively describe the inflammatory status. Digital infrared thermal imaging (DITI) detects local temperature and may ...

journal_title：Acta ophthalmologica

authors： Shih SR,Li HY,Hsiao YL,Chang TC

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:To compare the efficacy and visual outcomes after femtosecond laser small incision lenticule extraction (SMILE) and femtosecond laser-assisted laser in situ keratomileusis (FS-LASIK) in correcting high myopia. METHODS:This prospective, randomized study included patients who underwent SMILE or FS-LASIK for the ...

journal_title：Acta ophthalmologica

authors： Qian Y,Chen X,Naidu RK,Zhou X

更新日期：2020-03-01 00:00:00

abstract：:Our review aims to provide an update of management protocols for congenital nasolacrimal duct obstruction (CNDO). Although early probing performed before the age of 1 year was traditionally recommended, many reports have since confirmed high frequencies of spontaneous resolution during the first year of life. Accordin...

journal_title：Acta ophthalmologica

authors： Takahashi Y,Kakizaki H,Chan WO,Selva D

更新日期：2010-08-01 00:00:00

abstract：PURPOSE:To assess the trend patterns and gender disparity in global burden of vision loss due to diabetic retinopathy (DR) by year, age, region and socioeconomic status using prevalence and years lived with disability (YLDs) from Global Burden of Disease (GBD) study 2017. METHODS:Prevalence and YLDs data of vision los...

journal_title：Acta ophthalmologica

authors： Xu Y,Wang A,Lin X,Xu J,Shan Y,Pan X,Ye J,Shan PF

更新日期：2020-10-29 00:00:00

abstract：PURPOSE:To describe the retinal structure of a group of patients affected by methylmalonic aciduria with homocystinuria cblC type, caused by mutations in the MMACHC gene, using spectral domain optical coherence tomography (SD-OCT). METHODS:Young patients (n = 11, age 0-74 months) with cblC disease, detected by newborn...

journal_title：Acta ophthalmologica

authors： Bacci GM,Donati MA,Pasquini E,Munier F,Cavicchi C,Morrone A,Sodi A,Murro V,Garcia Segarra N,Defilippi C,Bussolin L,Caputo R

更新日期：2017-12-01 00:00:00

abstract：PURPOSE:To investigate the cerebrospinal fluid (CSF) dynamics along the entire optic nerve (ON) in patients with normal-tension glaucoma (NTG). METHODS:Retrospective analysis of computed tomographic (CT) cisternographies in Caucasian patients with NTG. Fifty-six patients (99 of 112 eyes) fulfilled the diagnostic crite...

journal_title：Acta ophthalmologica

authors： Pircher A,Montali M,Wostyn P,Pircher J,Berberat J,Remonda L,Killer HE

更新日期：2018-08-01 00:00:00

abstract：PURPOSE:To examine the patient's subjective visual sensations during cataract surgery performed under topical anaesthesia. METHODS:Prospective, non-randomized, cohort study. One hundred and thirty-two patients were interviewed by standard questionnaire within 1 hr of uncomplicated cataract surgery performed under topi...

journal_title：Acta ophthalmologica

authors： Biró Z,Schvöller M

更新日期：2008-12-01 00:00:00

abstract：PURPOSE:Proliferative diabetic retinopathy (PDR) is characterized by ischaemia- and inflammation-induced neovascularization, but the pathological vascular differentiation in PDR remains poorly characterized. Here, endothelial progenitor and growth properties, as well as potential lymphatic differentiation, were investi...

journal_title：Acta ophthalmologica

authors： Loukovaara S,Gucciardo E,Repo P,Vihinen H,Lohi J,Jokitalo E,Salven P,Lehti K

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:To establish whether or not the dynamics of saccadic eye movements are significantly changed in patients with different stages of thyroid-associated ophthalmopathy (TAO) and, subsequently, if analysis of saccades could serve as an additional diagnostic tool for early detection of inflammatory activity in TAO. ...

journal_title：Acta ophthalmologica

authors： Schworm HD,Bolzani R,Benassi M,Tallstedt L,Rydberg A,Lennerstrand G,Ygge J

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Primary open-angle glaucoma (POAG) is the main cause of irreversible blindness worldwide. Matrix metalloproteinases (MMPs) and their regulators (TIMPs and ILs) have been extensively studied as POAG risk factors. Recent reports have showed several single-nucleotide polymorphisms (SNPs) for MMPs, TIMPs and ILs...

journal_title：Acta ophthalmologica

authors： Markiewicz L,Majsterek I,Przybylowska K,Dziki L,Waszczyk M,Gacek M,Kaminska A,Szaflik J,Szaflik JP

更新日期：2013-11-01 00:00:00

abstract：:A growing number of studies have reported a link between vascular damage and glaucoma based on optical coherence tomography angiography (OCTA) imaging. This multitude of studies focused on different regions of interest (ROIs) which offers the possibility to draw conclusions on the most discriminative locations to diag...

journal_title：Acta ophthalmologica

authors： Bekkers A,Borren N,Ederveen V,Fokkinga E,Andrade De Jesus D,Sánchez Brea L,Klein S,van Walsum T,Barbosa-Breda J,Stalmans I

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:To examine the movement of air injected in the cornea in simulated deep anterior lamellar keratoplasty (DALK), from the needle tip to the formation of different types of big bubbles (BB) and to ascertain how air travels through the stroma and pre-Descemet's layer [Dua's layer (PDL)] to create a type-1 (air betw...

journal_title：Acta ophthalmologica

authors： Dua HS,Faraj LA,Kenawy MB,AlTaan S,Elalfy MS,Katamish T,Said DG

更新日期：2018-02-01 00:00:00

abstract：PURPOSE:To examine visual acuity, refraction and ocular status before, during and after hyperbaric oxygen therapy (HBOT). METHODS:Twenty-nine patients underwent 40 standard protocol HBOT treatments. In all subjects, refraction and best corrected visual acuity were measured at baseline and after ten, 20, 30 and 40 trea...

journal_title：Acta ophthalmologica

authors： Riedl P,Škiljić D,Arnell P,Wannholt R,Zetterberg M,Andersson Grönlund M

更新日期：2019-09-01 00:00:00

abstract：PURPOSE:To evaluate the safety and efficacy of 1.5% dexamethasone nanoparticle (DexNP) drops in eyes with non-infectious uveitic macular oedema and vitritis. METHODS:In a prospective pilot study, DexNP drops were administered four times a day for 4 weeks followed by drops tapering over a period of another 4 weeks. Fol...

journal_title：Acta ophthalmologica

authors： Shulman S,Jóhannesson G,Stefánsson E,Loewenstein A,Rosenblatt A,Habot-Wilner Z

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:Elevated intra-ocular pressure (IOP) has been identified as a major risk factor for glaucoma. Additionally, extensive literature depicts a vascular dysfunction to exist in these patients. However, a large ocular blood flow-oriented trial to integrate these findings in the clinical setting is lacking. This study...

journal_title：Acta ophthalmologica

authors： Abegão Pinto L,Willekens K,Van Keer K,Shibesh A,Molenberghs G,Vandewalle E,Stalmans I

更新日期：2016-09-01 00:00:00

abstract：PURPOSE:To report normative data on visual acuity (VA) for near and distance, refraction, ocular alignment, ocular motility and stereo acuity in a cohort of children aged 4.5-7 years. METHODS:A total of 950 children with normal development from the municipality of Roskilde, Denmark, were invited to participate in an o...

journal_title：Acta ophthalmologica

authors： Sandfeld L,Weihrauch H,Tubaek G,Mortzos P

更新日期：2018-06-01 00:00:00

abstract：PURPOSE:To report our experience in endoscopic dacryocystorhinostomy in treating nasolacrimal duct obstruction over a 14-year period. METHODS:Retrospective case series carried out over a 14-year period from 1999 to 2014. A total of 624 endoscopic dacryocystorhinostomy procedures were performed in 442 patients who were...

journal_title：Acta ophthalmologica

authors： Coumou AD,Genders SW,Smid TM,Saeed P

更新日期：2017-02-01 00:00:00

abstract：:Vitreomacular traction resulting from lacking, incomplete or anomalous posterior vitreous detachment is suspected to play a crucial role in the pathogenesis of different forms of age-related macular degeneration (AMD) along with the known mechanisms. It is probable that the fundamental pathomechanisms of AMD formation...

journal_title：Acta ophthalmologica

authors： Schulze S,Hoerle S,Mennel S,Kroll P

更新日期：2008-08-01 00:00:00

abstract：PURPOSE:To determine the molecular genetic cause in previously unreported probands with optic atrophy from the United Kingdom, Czech Republic and Canada. METHODS:OPA1 coding regions and flanking intronic sequences were screened by direct sequencing in 82 probands referred with a diagnosis of bilateral optic atrophy. D...

journal_title：Acta ophthalmologica

authors： Liskova P,Tesarova M,Dudakova L,Svecova S,Kolarova H,Honzik T,Seto S,Votruba M

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of the ultrasonic circular cyclocoagulation procedure in patients with open-angle glaucoma naïve of previous filtering surgery. METHODS:Prospective non-comparative interventional clinical study conducted in five French University Hospitals. Thirty eyes of 30 patients with op...

journal_title：Acta ophthalmologica

authors： Aptel F,Denis P,Rouland JF,Renard JP,Bron A

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To examine whether real-world clinical patients with macular oedema (MO) receiving intravitreal antivascular endothelial growth factor (VEGF) therapy have a higher mortality compared with a matched reference population. METHODS:A population-based, retrospective cohort study of 26 386 patients from Finland, fro...

journal_title：Acta ophthalmologica

authors： Loukovaara S,Haukka J

更新日期：2021-01-02 00:00:00

abstract：PURPOSE:This study aimed to investigate whether mild laser treatment of soft drusen maculopathy might reduce the incidence of choroidal neovascularization (CNV) and/or significantly reduce loss of visual acuity compared with outcomes in a control group. METHODS: A total of 135 patients (mean age 70.4 years) were rando...

journal_title：Acta ophthalmologica

authors： Frennesson CI,Bek T,Jaakkola A,Nilsson SE,Prophylactic Laser Treatment Study Group.

更新日期：2009-11-01 00:00:00

abstract：PURPOSE:To investigate the value of posterior keratometry in the assessment of surgically induced astigmatic change (AC) in cataract surgery, with particular emphasis on the influence of test-retest variability. METHODS:Seventy-seven eyes of 77 cataract patients scheduled for routine cataract surgery were enrolled. Al...

journal_title：Acta ophthalmologica

authors： Klijn S,van der Sommen CM,Sicam VA,Reus NJ

更新日期：2016-08-01 00:00:00

abstract：PURPOSE:To assess the effects of multifocal soft contact lenses (MF SCLs) used for myopia control on visual acuity (VA) and subjective quality of vision. METHODS:Twenty-four young adult myopes had baseline high and low-contrast VAs and refractions measured and quality of vision assessed by the Quality of Vision (QoV) ...

journal_title：Acta ophthalmologica

authors： Kang P,McAlinden C,Wildsoet CF

更新日期：2017-02-01 00:00:00

abstract：PURPOSE:To examine agreement between intraocular pressure (IOP) measurements made using the rebound tonometer Icare ic200 (RT200) and the Perkins handheld applanation tonometer (PAT) in patients with primary congenital glaucoma (PCG). The impacts of several covariables on measurements using the two devices were also as...

journal_title：Acta ophthalmologica

authors： Morales-Fernandez L,Pérez-García P,Saenz-Frances F,Molero-Senosiain M,Garcia-Saenz S,Dora Mendez C,Santos Bueso E,Garcia-Feijoo J,Martinez-de-la-Casa JM

更新日期：2020-12-23 00:00:00

abstract：:To review binocular and accommodative disorders documented after corneal or intraocular refractive surgery, in normal healthy prepresbyopic patients. A bibliographic revision was performed; it included works published before 1st July 2017 where accommodation and/or binocularity was assessed following any type of refra...

journal_title：Acta ophthalmologica

authors： García-Montero M,Albarrán Diego C,Garzón-Jiménez N,Pérez-Cambrodí RJ,López-Artero E,Ondategui-Parra JC

更新日期：2019-03-01 00:00:00

abstract：PURPOSE:The aim of this study was to assess the brain regions associated with impaired performance in a virtual, dynamic collision avoidance task, in a group of patients with homonymous visual field defects (HVFDs) because of unilateral vascular brain lesions. METHODS:Overall task performance was quantitatively assess...

journal_title：Acta ophthalmologica

authors： Papageorgiou E,Hardiess G,Wiethölter H,Ackermann H,Dietz K,Mallot HA,Schiefer U

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:To investigate the coexistence of ocular microvascular and systemic macrovascular abnormalities in early stage, newly diagnosed and previously untreated normal tension glaucoma patients (NTG). METHODS:Retinal vascular reactivity to flickering light was assessed in 19 NTG and 28 age-matched controls by means of...

journal_title：Acta ophthalmologica

authors： Mroczkowska S,Ekart A,Sung V,Negi A,Qin L,Patel SR,Jacob S,Atkins C,Benavente-Perez A,Gherghel D

更新日期：2012-11-01 00:00:00

abstract：PURPOSE:This study aimed to investigate the retinal thickness analyser (RTA) as a means to identify the presence of cystoid macular oedema (CMO) in children with uveitis, whether the course of CMO can be monitored using this method, and whether there is a trend towards a correlation between macular oedema and visual ac...

journal_title：Acta ophthalmologica

authors： Maca SM,Garhofer G,Kiss C,Barisani-Asenbauer T

更新日期：2008-05-01 00:00:00