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Radiation-Induced Organizing Pneumonia: A Characteristic Disease that Requires Symptom-Oriented Management.

Abstract：

:Radiation-induced organizing pneumonia (RIOP) is an inflammatory lung disease that is occasionally observed after irradiation to the breast. It is a type of secondary organizing pneumonia that is characterized by infiltrates outside the irradiated volume that are sometimes migratory. Corticosteroids work acutely, but relapse of pneumonia is often experienced. Management of RIOP should simply be symptom-oriented, and the use of corticosteroids should be limited to severe symptoms from the perspective not only of cost-effectiveness but also of cancer treatment. Once steroid therapy is started, it takes a long time to stop it due to frequent relapses. We review RIOP from the perspective of its diagnosis, epidemiology, molecular pathogenesis, and patient management.

journal_name

Int J Mol Sci

journal_title

International journal of molecular sciences

authors

Otani K,Seo Y,Ogawa K

doi

10.3390/ijms18020281

subject

Has Abstract

pub_date

2017-01-27 00:00:00

issue

2

issn

1422-0067

pii

ijms18020281

journal_volume

18

pub_type

杂志文章,评审

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