Abstract:
:It has been suggested that future application of stem-cell derived gametes (SCD-gametes) might lead to the possibility for same-sex couples to have genetically related children. Still, for this to become possible, the technique of gamete derivation and techniques of reprogramming somatic cells to a pluripotent state (directly or via somatic cell nuclear transfer) would have to be perfected. Moreover, egg cells would have to be derived from male cells and sperm cells from female cells, which is believed to be particularly difficult, if not impossible. We suggest a more plausible scenario to provide same-sex couples with the possibility to parent a child who is genetically related to both parents. Although technical feasibility is an advantage (also in terms of safety), disadvantages are that cooperation of a donor of the opposite sex is still required and that the partners are genetically linked to the resulting child in a different degree. However, since in our scenario the donor's genetic contribution would not outweigh any of the parents' genetic contribution, this alternative route may ease the fear for a possible parental claim by the donor. Like many other applications in the field of infertility treatment, the goal to create SCD-gametes for reproductive purposes is largely based on the high value attributed to genetic parenthood. Although we believe that genetic relatedness is neither a necessary nor a sufficient condition for 'good' parenthood, we do believe that many people may consider our scenario a welcome alternative.
journal_name
J Med Ethicsjournal_title
Journal of medical ethicsauthors
Segers S,Mertes H,Pennings G,de Wert G,Dondorp Wdoi
10.1136/medethics-2016-103863subject
Has Abstractpub_date
2017-10-01 00:00:00pages
688-691issue
10eissn
0306-6800issn
1473-4257pii
medethics-2016-103863journal_volume
43pub_type
杂志文章abstract::The aim of regenerative medicine is to reconstruct tissue that has been lost or pathologically altered. Therapeutic cloning seems to offer a method of achieving this aim; however, the ethical debate surrounding human therapeutic cloning is highly controversial. Artificial parthenogenesis-obtaining embryos from unferti...
journal_title:Journal of medical ethics
pub_type: 历史文章,杂志文章,评审
doi:10.1136/jme.2004.010199
更新日期:2005-12-01 00:00:00
abstract::Coercion and pressure in mental healthcare raise moral questions. This article focuses on moral questions raised by the everyday practice of pressure and coercion in the care for the mentally ill. In view of an example from literature-the story of Ulysses and the Sirens-several ethical issues surrounding this practice...
journal_title:Journal of medical ethics
pub_type: 杂志文章,多中心研究
doi:10.1136/jme.2005.015545
更新日期:2007-10-01 00:00:00
abstract::The editorial in the September 1982 issue of this journal and many articles before and since have addressed the problem of informed consent. Is it possible? Is it a useful concept? Is there anything new to be said about it? In this article the basic rationale of the rule (patient autonomy) is explained and the extent ...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.9.2.69
更新日期:1983-06-01 00:00:00
abstract::In a recent article, Udo Schuklenk and Suzanne van de Vathorst argued in favour of a legal option of physician-assisted death for patients with 'treatment-resistant' depression. In this commentary, I contend that their argument neglects the important consideration of the professional integrity of physicians. In light ...
journal_title:Journal of medical ethics
pub_type: 评论,杂志文章
doi:10.1136/medethics-2015-103060
更新日期:2015-11-01 00:00:00
abstract:PURPOSE:Explore public attitudes towards the trade-offs between justice and medical outcome inherent in organ allocation decisions. BACKGROUND:The US Task Force on Organ Transplantation recommended that considerations of justice, autonomy and medical outcome be part of all organ allocation decisions. Justice in this c...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.2006.018291
更新日期:2008-02-01 00:00:00
abstract::Conflict is an important consideration in the intensive care unit (ICU). In this setting, conflict most commonly occurs over the 'best interests' of the incapacitated adult patient; for instance, when families seek aggressive life-sustaining treatments, which are thought by the medical team to be potentially inappropr...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/medethics-2020-106177
更新日期:2020-07-06 00:00:00
abstract:OBJECTIVES:To analyse the decision making for end of life care for patients with cancer at a teaching hospital in Japan at two periods 10 years apart. DESIGN AND SETTING:Retrospective study conducted in a 550 bed community teaching hospital in Okinawa, Japan. PATIENTS:There were 124 terminally ill cancer patients (45...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.2003.000125
更新日期:2004-06-01 00:00:00
abstract::In a recent article in this journal, Anna Christensen raises an 'Epicurean challenge' to Don Marquis' much-discussed argument for the immorality of abortion. According to Marquis' argument, abortion is pro tanto morally wrong because it deprives the fetus of 'a future like ours'. Drawing on the Epicurean idea that dea...
journal_title:Journal of medical ethics
pub_type: 评论,杂志文章
doi:10.1136/medethics-2019-105771
更新日期:2020-04-01 00:00:00
abstract::This paper considers the ethics of routine antenatal HIV testing and the role of informed consent within such a policy in order to decide how we should proceed in this area--a decision that ultimately rests on the relative importance we give to public health goals on the one hand and respect for individual autonomy on...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.2006.018861
更新日期:2007-08-01 00:00:00
abstract::This opinion piece aims to situate the placebo effect within the field of psychiatric treatment. To accomplish this, the placebo is explored at the centre of an often heated debate between three discrete perspectives: the clinical trial researcher, the placebo researcher and the clinician. Each occupational perspectiv...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/medethics-2013-101410
更新日期:2014-06-01 00:00:00
abstract::In an earlier article in this journal, I advanced five ethical arguments in favour of a voluntary, unpaid system of blood donation. In his reply to my article, Hugh McLachlan criticised one of those arguments, namely, the argument that an unpaid system promotes altruism and social solidarity. In this reply to Dr. McLa...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.24.4.255
更新日期:1998-08-01 00:00:00
abstract:OBJECTIVES:To compare the perceptions of physician executives and clinicians regarding ethical issues in Saudi Arabian hospitals and the attributes that might lead to the existence of these ethical issues. DESIGN:Self-completion questionnaire administered from February to July 1997. SETTING:Different health regions i...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.25.1.51
更新日期:1999-02-01 00:00:00
abstract::This is the first contribution to a new JME column, "At the coalface," to which readers are invited to relate ethical problems they have encountered in their work. An adolescent patient requested that the author, a general practitioner, certify that he was medically fit to box. Toon attempted to dissuade him from bo...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.14.2.69
更新日期:1988-06-01 00:00:00
abstract::Translational research is now a critically important current in academic medicine. Researchers in all health-related fields are being encouraged not only to demonstrate the potential benefits of their research but also to help identify the steps through which their research might be 'made practical'. This paper consid...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.2009.029785
更新日期:2010-04-01 00:00:00
abstract::The increasing availability of DNA-based diagnostic tests has raised issues about whether these should be applied to the population at large in order to identify, treat or prevent a range of diseases. DNA tests raise concerns in the community for several reasons. There is the possibility of stigmatisation and discrimi...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.25.2.209
更新日期:1999-04-01 00:00:00
abstract::This paper investigates the medical law and ethics (MEL) learning needs of Foundation doctors (FYs) by means of a national survey developed in association with key stakeholders including the General Medical Council and Health Education England. Four hundred sevnty-nine doctors completed the survey. The average self-re...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/medethics-2019-105961
更新日期:2020-04-10 00:00:00
abstract:OBJECTIVE:Adolescents have had very limited access to research on biomedical prevention interventions despite high rates of HIV acquisition. One concern is that adolescents are a vulnerable population, and trials carry a possibility of harm, requiring investigators to take additional precautions. Of particular concern ...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/medethics-2012-100821
更新日期:2013-12-01 00:00:00
abstract::Principles of autonomy and self-determination have been upheld as vital to modern-day medical and ethical practice. However, the complexities of current health care and changes in the expectation of some patients and their families justify a review of such concepts. Their limitations and relativities may suggest that ...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.15.1.12
更新日期:1989-03-01 00:00:00
abstract::The traditional view that having a personality disorder, unlike other mental disorders, is not usually reason enough to consider a person incompetent to make healthcare decisions is challenged. The example of a case in which a woman was treated for a physical disorder without her consent illustrates that personality d...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.2007.023341
更新日期:2008-10-01 00:00:00
abstract::What happens when we discover that a severely mentally handicapped girl, resident under our care, is heavily pregnant? What options are open to us in her management? What are the legal and ethical issues involved? How do we ensure that she receives the best possible care and protection and will the involvement of the ...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.15.4.197
更新日期:1989-12-01 00:00:00
abstract::The Handicap Division of the Society for the Protection of the Unborn Child (SPUC) organized picketing of Britain's Medical Research Council to protest against trials of multivitamin supplementation for high-risk pregnant women to prevent development of spina bifida in the fetus. The trials have been condemned by man...
journal_title:Journal of medical ethics
pub_type: 新闻
doi:10.1136/jme.10.3.165
更新日期:1984-09-01 00:00:00
abstract::We propose a principle of sustainability to complement established principles used for justifying healthcare resource allocation. We argue that the application of established principles of equal treatment, need, prognosis and cost-effectiveness gives rise to what we call negative dynamics: a gradual depletion of the v...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/medethics-2020-106644
更新日期:2021-02-01 00:00:00
abstract::The most publicly justifiable application of human cloning, if there is one at all, is to provide self-compatible cells or tissues for medical use, especially transplantation. Some have argued that this raises no new ethical issues above those raised by any form of embryo experimentation. I argue that this research is...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.25.2.87
更新日期:1999-04-01 00:00:00
abstract::One of the central arguments given to resist testing currently healthy, asymptomatic children for adult-onset diseases is that they may be psychologically harmed by the knowledge gained from such tests. In this discussion I examine two of the most serious arguments: children who are tested may face limited futures, an...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.2006.019802
更新日期:2008-04-01 00:00:00
abstract::With the recent developments in the Human Genome Mapping Project and the new technologies that are developing from it there is a renewal of concern about eugenic applications. Francis Galton (b1822, d1911), who developed the subject of eugenics, suggested that the ancient Greeks had contributed very little to social t...
journal_title:Journal of medical ethics
pub_type: 传,历史文章,杂志文章
doi:10.1136/jme.24.4.263
更新日期:1998-08-01 00:00:00
abstract::This point of view compares the issue of informed patient consent primarily as it operates in Australia and the United Kingdom. It affords an overview, also, of the applicable law in the United States and Canada. It particularly focuses on the legal test to be applied to patient consent as established in the Bolam cas...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.21.1.5
更新日期:1995-02-01 00:00:00
abstract:OBJECTIVES:to assess physicians' and patients' views in Saudi Arabia (KSA) towards involving the patient versus the family in the process of diagnosis disclosure and decision-making, and to compare them with views from the USA and Japan. DESIGN:A self-completion questionnaire (used previously to study these issues in ...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.2006.019638
更新日期:2008-04-01 00:00:00
abstract::In this article, we discuss the ethical dimensions for the prescribing behaviours of opioids for a chronic pain patient, a scenario commonly witnessed by many physicians. The opioid epidemic in the USA and Canada is well known, existing since the late 1990s, and individuals are suffering and dying as a result of the e...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/medethics-2018-105099
更新日期:2019-04-01 00:00:00
abstract::The author responds to Professor Kottow's criticisms, explaining numerous errors and misconceptions. ...
journal_title:Journal of medical ethics
pub_type: 评论,杂志文章
doi:10.1136/jme.25.4.344
更新日期:1999-08-01 00:00:00
abstract:OBJECTIVES:To explore attitudes and reasoning among Swedish physicians and the general public regarding the withdrawal of life-sustaining treatment at a competent patient's request. DESIGN:A vignette-based postal questionnaire including 1202 randomly selected individuals in the county of Stockholm and 1200 randomly se...
journal_title:Journal of medical ethics
pub_type: 杂志文章
doi:10.1136/jme.2009.034967
更新日期:2010-05-01 00:00:00