Melorheostosis with recurrent soft-tissue components: a histologically confirmed case.

Abstract:

:Melorheostosis is a very rare disorder characterized by irregular cortical thickening seen on radiographs. In this paper, we present a case of melorheostosis with microscopically confirmed soft-tissue components. The patient was a 51-year-old man who complained of severe pain in the lateral aspect of his right knee. The excision of an ossified soft-tissue lesion relieved intractable pain that had lasted 20 years. Microscopically, the cortex of the affected fibula was composed of thick compact bone and the soft-tissue component consisted of dense compact bone without endochondral ossification. The presence of soft-tissue osseous nodules around the joints is one of the specific conditions for melorheostosis and should be differentiated from synovial chondromatosis. The ossified soft-tissue lesion in our patient is to our knowledge the first reported case of the histologically confirmed soft-tissue component of melorheostosis, which differs from that of synovial chondromatosis.

journal_name

Skeletal Radiol

journal_title

Skeletal radiology

authors

Hasegawa S,Kanda S,Imada H,Yamaguchi T,Akiyama T

doi

10.1007/s00256-016-2562-9

subject

Has Abstract

pub_date

2017-03-01 00:00:00

pages

399-404

issue

3

eissn

0364-2348

issn

1432-2161

pii

10.1007/s00256-016-2562-9

journal_volume

46

pub_type

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