Abstract:
OBJECTIVE:To explore the link between a patient acceptable symptom state (PASS) and patient-perceived impact in rheumatoid arthritis (RA) and psoriatic arthritis (PsA). METHODS:This was a cross-sectional study of unselected patients with definite RA or PsA. Pain, functional capacity, fatigue, coping, and sleep disturbance were assessed using a numeric rating scale (0-10) and compared between patients in PASS or not (Cohen's effect sizes). The domains of health associated with PASS status were assessed by multivariate forward logistic regression, and PASS thresholds were determined using the 75th percentile method and receiver operating characteristic analyses. RESULTS:Among 977 patients (531 with RA, 446 with PsA), the mean ± SD age was 53.4 ± 13.2 years, mean ± SD disease duration was 11.2 ± 10.0 years, and 637 (65.8%) were women. In all, 595 patients (60.9%) were in PASS; they had lower symptom levels, and all domains of health except sleep disturbance discriminated clearly between patients in PASS or not (effect sizes 0.73-1.45 in RA and 0.82-1.52 in PsA). In multivariate analysis, less pain and better coping were predictive of being in PASS. Odds ratios were: RA pain 0.80 (95% confidence interval [95% CI] 0.67-0.96), PsA pain 0.63 (95% CI 0.52-0.75), RA coping 0.84 (95% CI 0.74-0.96), and PsA coping 0.83 (95% CI 0.71-0.97). The cutoffs of symptom intensity (range 0-10), corresponding to PASS for the 5 domains of health and the 2 diseases were similar, i.e., approximately 4-5. CONCLUSION:In RA and PsA, PASS was associated with the 5 domains of health analyzed, and in particular with less pain and better coping.
journal_name
Arthritis Care Res (Hoboken)journal_title
Arthritis care & researchauthors
Puyraimond-Zemmour D,Etcheto A,Fautrel B,Balanescu A,de Wit M,Heiberg T,Otsa K,Kvien TK,Dougados M,Gossec Ldoi
10.1002/acr.23176subject
Has Abstractpub_date
2017-10-01 00:00:00pages
1504-1509issue
10eissn
2151-464Xissn
2151-4658journal_volume
69pub_type
杂志文章abstract:OBJECTIVE:To assess the frequency of fibromyalgia syndrome (FMS), depression, and sleep disorders in patients with granulomatosis with polyangiitis (Wegener's) (GPA). METHODS:The London Fibromyalgia Epidemiologic Study Screening Questionnaire (LFESSQ), Symptom Intensity Scale, Epworth Sleepiness Scale (ESS), and the B...
journal_title:Arthritis care & research
pub_type: 杂志文章
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journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究,随机对照试验
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journal_title:Arthritis care & research
pub_type: 杂志文章
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abstract:OBJECTIVE:Rheumatoid arthritis (RA) is the most common inflammatory disorder affecting the cervical spine. The purpose of this study was to characterize the atloaxial involvement with magnetic resonance imaging (MRI) in patients with early RA at the moment of diagnosis and after 18 months of a tight control therapy. M...
journal_title:Arthritis care & research
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更新日期:2011-11-01 00:00:00
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journal_title:Arthritis care & research
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更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:Smoking has been associated with increased systemic lupus erythematosus (SLE) risk, but the biologic basis for this association is unknown. We investigated whether women's smoking was positively associated with SLE-associated pro-inflammatory chemokines/cytokines, [stem cell factor (SCF), B-lymphocyte stimul...
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更新日期:2017-04-01 00:00:00
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更新日期:2013-08-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2015-10-01 00:00:00
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更新日期:2018-03-01 00:00:00
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更新日期:2019-02-01 00:00:00
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journal_title:Arthritis care & research
pub_type: 杂志文章
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更新日期:2015-07-01 00:00:00
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更新日期:2016-06-01 00:00:00
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journal_title:Arthritis care & research
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更新日期:2019-10-01 00:00:00
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journal_title:Arthritis care & research
pub_type: 杂志文章,多中心研究
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更新日期:2010-05-01 00:00:00
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journal_title:Arthritis care & research
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更新日期:2015-01-01 00:00:00
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journal_title:Arthritis care & research
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更新日期:2019-12-01 00:00:00
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更新日期:2020-07-23 00:00:00
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更新日期:2012-02-01 00:00:00
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